Clinical trials: Heart Disease, Coronary
Heart Failure, Ischemic Cardiomyopathy
Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure.
The aim of the study is to investigate safety and efficacy of intramyocardial implantation of allogeneic mesenchymal stem cells in patients with end-stage ischemic cardiomyopathy undergoing left ventricular assist device…
- Trial name
- NCT01759212
- Testing
- Allogeneic stem cells implantation
- Where
- Greece
- Volunteers
- 1 people
- Sponsor
- AHEPA University Hospital
Reperfusion Injury, Myocardial
The Role of Colchicine in Reducing The Rate of Myocardial Reperfusion Injury
The goal of this clinical trial is to investigate the role of colchicine in reducing the rate of myocardial reperfusion injury in patients with ST-elevation myocardial infarction after primary percutaneous coronary intervention.
- Trial name
- NCT05734612
- Testing
- Colchicine
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Indonesia
Heart Failure
Decision Support System for Diagnosis and Progression of Heart Failure
Heart failure (HF) is a complex clinical syndrome associated with impaired heart function, poor quality of life for patients and high healthcare costs.
- Trial name
- STRATIFYHF (NCT06377319)
- Testing
- Cardiac Output Response to Stress (CORS) test
- Volunteers
- 1,600 people
- Sponsor
- Coventry University
Heart Failure, Congestive
Heart Failure, Functional and Cognitive Decline, and Psychiatric Symptoms in Nursing Home Patients
Heart failure is very common in the elderly, in whom it may lead to functional and intellectual problems. Functional problems include loss in the ability to perform basic tasks of daily living such as bathing or dressing.
- Trial name
- NCT00182065
- Where
- Canada
- Volunteers
- 586 people
- Sponsor
- McMaster University
Atrial Fibrillation
Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation
The purpose of this study is to evaluate the safety and effectiveness of empirical posterior wall isolation (PWI), left atrial appendage electrical isolation (LAAEI) and coronary sinus isolation (CSI) when compared to pulmonary…
- Trial name
- PLEA (NCT04216667)
- Testing
- Catheter ablation
- Where
- 16 sites in United States, Argentina and 5 more
- Volunteers
- 124 people
- Sponsor
- Montefiore Medical Center
Coronary Artery Disease, Acute Coronary Syndrome
Bioresorbable Polymer-Coated EES in Patients at High Bleeding Risk Undergoing PCI Followed by 1-Month DAPT
Objective: To evaluate the safety of bioresorbable polymer-coated everolimus-eluting Synergy® stent followed by 1-month dual antiplatelet therapy in patients at high-bleeding risk.
- Trial name
- POEM (NCT03112707)
- Testing
- Aspirin, P2Y12 inhibitor
- Where
- Italy
- Volunteers
- 1,023 people
- Sponsor
- Humanitas Hospital, Italy
Coronary Artery Disease Left Main
Imaging and Physiology for Intermediate Left Main Stem Stenosis
The present research aims to determine the impact of stenoses in downstream vessels on the FFR and iFR measurements of left main coronary artery (LMCA) stenoses of intermediate severity as determined by coronary angiography.
- Trial name
- VIP-LMS (NCT04531007)
- Testing
- iFR/ FFR/ IVUS/ OCT
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Cardiac Arrest, Anoxic Encephalopathy
TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation
The purpose of this study is to estimate the effect of medical treatment of electro-encephalographic status epilepticus on neurological outcome of patients with postanoxic encephalopathy after cardiac arrest.
- Conditions
- Cardiac Arrest, Anoxic Encephalopathy, Status Epilepticus
- Trial name
- TELSTAR (NCT02056236)
- Testing
- Anti-epileptic drugs, No anti-epileptic drugs
- Where
- 11 sites in Belgium, Netherlands
- Volunteers
- 172 people
- Sponsor
- University of Twente
Rheumatic Heart Disease
Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System
The first primary objective of this study is to determine the diagnostic performance (sensitivity and specificity) of primary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation…
- Trial name
- ADD-RHD 2B (NCT05668611)
- Testing
- Primary Training Phase, Primary Assessment Phase, Primary Screening Phase
- Where
- Uganda
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Heart Failure
Evalutation of a Hybrid Care Pathway With Remote MONitoring for Heart Failure
Heart failure is a long-term condition in which the heart cannot pump blood as well as it should. People with heart failure often need to be admitted to hospital when their symptoms suddenly get worse, which affects their quality…
- Trial name
- HARMONY-HF (NCT07680634)
- Testing
- Hybrid heart failure care pathway
- Where
- 7 sites in Netherlands
- Volunteers
- 6,000 people
- Sponsor
- St. Antonius Hospital
Heart Failure, Type 2 Diabetes
Optimizing In-hospital Use of Evidence-based Therapies for Patients With Cardio-Renal-Metabolic Disease
This study will be a prospective randomized implementation trial for patients hospitalized with heart failure, chronic kidney disease, and/or type 2 diabetes mellitus within Duke University Medical Center.
- Conditions
- Heart Failure, Type 2 Diabetes, Chronic Kidney Diseases
- Trial name
- IMPLEMENT-CRM (NCT05781334)
- Testing
- Virtual Consult Intervention
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Duke University
Respiratory Disorder, Heart Disorder
Clinical Validation of Tele-stethoscope System Digital
Acute respiratory infections and other respiratory and cardiology diseases like COPD or heart failure are important causes of morbidity and mortality around the world.
- Trial name
- TeleCáceres (NCT03596541)
- Testing
- Heart and Respiratory Auscultation of an open real-time tele-stethoscopy system (EHAS-Fundatel digital stethoscope)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Coronary Heart Disease
The Comparative Study of OCT，Gemstone CT and 320-detector Row Spiral CT for Evaluating Restenosis of Coronary Artery Stent
In-stent restenosis is a major reason of coronary heart disease recurrence .Even in drug eluting stent(DES), Restenosis rate could be up to 10% in diabetes and complex lesions though it was about 3-5% in general.
- Trial name
- NCT02219594
- Testing
- CT image for patient with suspected in-stent restenosis
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xuzhou Central Hospital
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Heart Failure, Diastolic, Heart Failure，Congestive
PREFERS (Preserved and Reduced Ejection Fraction Epidemiological Regional Study) Stockholm Heart Failure Study
Heart failure (HF) with preserved (HFpEF) or reduced (HFrEF) ejection fraction is associated with poor prognosis and quality of life.
- Trial name
- PREFERS (NCT03671122)
- Testing
- Cardiac imaging in the PREFERS and CABG PREFERS cohorts, Biomarker analysis in the PREFERS and CABG PREFERS chorts, Cardiac biopsies in the CABG PREFERS cohort
- Where
- Sweden
- Volunteers
- 683 people
- Sponsor
- Karolinska Institutet
Heart Failure
Experience in Being With Advanced Heart Failure Patients
The purpose of this study is to explore the experience in being with advanced Heart failure patients.
- Trial name
- NCT02437331
- Where
- Taiwan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Heart Failure
Optimal Programming to Improve Mechanical Indices, Symptoms and Exercise in Cardiac Resynchronization Therapy.
This international study is assessing if repeat adjustment of the timing between the three leads in a cardiac resynchronization therapy (CRT) defibrillator will increase the likelihood of benefit (symptoms and heart function)…
- Trial name
- OPTIMISE-CRT (NCT00489177)
- Testing
- A, B
- Where
- Canada
- Volunteers
- 461 people
- Sponsor
- University of Calgary
Takotsubo Cardiomyopathy, Sexual Dysfunction
Mindfulness-based Sex Therapy on Patients With Takotsubo Cardiomyopathy
Takotsubo cardiomyopathy (TC) is a type of non-ischemic cardiomyopathy in which there is a sudden temporary weakening of the myocardium. . In a recent study, women report more sexual dysfunction than men after 1 year after TC.
- Trial name
- NCT03372577
- Testing
- Mindfulness-Based Sex Therapy, Treatment as usual
- Where
- Iran
- Volunteers
- 450 people
- Sponsor
- Qazvin University Of Medical Sciences
Heart Failure
Electronic Transmission of Laboratory and Adherence Records of Heart Failure Patients to General Practitioners Screen
Patients with heart failure (HF) need multiple guideline-directed medications to control the systolic and/or diastolic ventricular dysfunction.
- Trial name
- LabAdhDoc (NCT04326101)
- Testing
- Transmission of adherence records
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Artery Ectasia
Endothelial Function in Patients With Ectatic Compared to Normal Coronary Arteries
The aim of this study is to show the frequency of endothelial dysfunction in patients suffering from ectatic coronary arteries as compared to those who have normal coronary arteries.
- Trial name
- NCT00548457
- Where
- Israel
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
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