Clinical trials: Heart Failure, Unspecified
Aortic Valve Disease
SMART - Systems Medicine of Heart Failure
The onset and course of heart failure (HF) is triggered by a complex regulatory network that includes stressors (pressure overload by individual anatomic hemodynamic settings), intrinsic (genes), environmental (regulating…
- Trial name
- NCT03172338
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- German Heart Institute
Heart Failure
Observational Study on the Patient's Ability to Use a Digital Platform in Heart Failure
Heart Failure has a global prevalence of 1 to 3% in the adult population with an incidence of 1 to 20 cases per 1,000 people. Furthermore, HF is often associated with a number of comorbidities (anaemia, arrhythmias, depression…
- Trial name
- CAP-IC (NCT06869408)
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- Persei Vivarium
Heart Failure, Mild Cognitive Impairment
Impact of Yoga on Cognitive Function
Mild cognitive impairment is highly prevalent in patients with heart failure and results in poor well-being and quality of life.
- Trial name
- NCT06434168
- Testing
- Yoga intervention, Control condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Auburn University
Heart Failure With Preserved Ejection Fraction
Risk Factors In Heart Failure Patients With Preserved Ejection Fraction
This study aimed to identify the independent risk factors associated with heart failure readmission, cardiac mortality and all-cause death among patients discharged from Xiangtan Central Hospital with heart failure and preserved…
- Trial name
- RIPE-HF (NCT06487468)
- Volunteers
- 9,419 people
- Sponsor
- Xiangtan Central Hospital
Acute on Chronic Systolic Congestive Heart Failure
Reversible Pulmonary Artery Banding as Simplified Management of End-stage Dilated Left Ventriculopathy in Early Life
The purpose of this study is to: 1) Remodel and restore left ventricular geometry and function. 2) Avoid the need for mechanical circulatory support (MCS) and/or cardiac transplantation (CT).
- Trial name
- NCT02652676
- Testing
- Reversible Pulmonary Artery Banding, GORE-TEX DualMesh EMERGE PLUS Biomaterial
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Loma Linda University
Heart Failure, Systolic Heart Failure
Effects of Postural Balance Exercises in Patients With Heart Failure
In this study, the effects of core stabilization and computerized wobble board exercise training programs on postural balance and functional exercise capacity in patients over 60 years of age with heart failure will be…
- Conditions
- Heart Failure, Systolic Heart Failure, Diastolic Heart Failure
- Trial name
- NCT04937790
- Testing
- Core stabilization group(CSG), Wobble board group (WBG)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Giresun University
Congestive Heart Failure
Electrophysiological Optimization of Left Ventricular Lead Placement in CRT
The purpose of this study is to investigate if "optimal electrical resynchronization" achieved by targeting left ventricular lead placement to the myocardial region with the latest electrical activation combined with post-implant…
- Trial name
- ElectroCRT (NCT02346097)
- Testing
- Cardiac Resynchronization Therapy (St. Jude Qaudripolar LV lead)
- Where
- Denmark
- Volunteers
- 122 people
- Sponsor
- University of Aarhus
Heart Failure With Preserved Ejection Fraction, Renal Denervation
Renal Denervation in Patients With Chronic Heart Failure With Preserved Ejection Fraction
This study aims to explore the potential of RDN as a therapy for HFpEF in a Prospective, Multicenter, Randomized, Blinded, Sham-controlled Study.
- Trial name
- RDN-HFPEF (NCT05715697)
- Testing
- Renal denervation and maintenance of heart failure medications
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xinjiang Medical University
Heart Failure
Education and Supportive Partners Improving Self-Care (ENSPIRE)
The purpose of the Education and Supportive Partners Improving Self-Care (ENSPIRE) study is to compare the effect of a Family Partnership Intervention (FPI) over patient and family education and usual heart failure care on…
- Trial name
- NCT00166049
- Testing
- Family Partnership Intervention (FPI), Patient and Family Education, Usual care with educational material
- Where
- 4 sites in United States
- Volunteers
- 170 people
- Sponsor
- Emory University
Congestive Heart Failure
A Trial of a CPR Video in Heart Failure Patients
This is a randomized controlled trial of a CPR video decision aid in patients with advanced congestive heart failure (CHF).
- Trial name
- NCT01653938
- Testing
- video decision aid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Heart Failure
Multidisciplinary Approach for High Risk Patients Leading to Early Diagnosis of Canadians in Heart Failure
The goal of this study is improve the screening of heart failure and identify patients early who are at risk of heart failure. The main question[s] it aims to answer are: will an electronic health records (EHR) case finding…
- Trial name
- MAPLE-CHF (NCT05859048)
- Testing
- NT-proBNP, AI echocardiogram, electrocardiogram
- Where
- 3 sites in Canada
- Volunteers
- 1,360 people
- Sponsor
- Cardiology Research UBC
Cardiovascular Diseases, Digital
Cardiovascular Digital Health Data Observatory
The COVID-19 health crisis has led to a drastic decrease in the rate of myocardial infarction without the causes being completely identified.
- Conditions
- Cardiovascular Diseases, Digital, Health Data, Observatory
- Trial name
- CADHO (NCT05316025)
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Grenoble
Heart Failure, Congestive, Cardiovascular Diseases
Effects of Exercise Training on Diastolic Heart Function in Postmenopausal Women
This study is a prospective follow-up study to the Dose-Response to Exercise in Women (DREW) study. In DREW, 450 overweight, sedentary postmenopausal women were randomly assigned to either a non-exercise control group or to 1 of…
- Trial name
- NCT00125476
- Testing
- Exercise
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure
Contemporary Modalities in Treatment of Heart Failure
The Contemporary Modalities In Treatment of Heart Failure Registry (COMMIT-HF) is an observational study on an all-comer systolic heart failure population hospitalized in a highly specialized cardiovascular center.
- Trial name
- COMMIT-HF (NCT02536443)
- Where
- Poland
- Volunteers
- 4,000 people
- Sponsor
- Silesian Centre for Heart Diseases
Heart Failure
Levosimendan in High Risk Heart Valve Surgery
Prospective, randomized, double blind study investigating the efficacy of levosimendan in heart failure after cardiac surgery. Study hypothesis: Levosimendan diminishes the need for adrenergic inotropic drugs and morbidity and…
- Trial name
- NCT00154115
- Testing
- levosimendan
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Kuopio University Hospital
Arrhythmia, Cardiovascular Diseases
Digitalis Investigation Group (DIG)
To determine if digitalis had a beneficial, harmful, or no effect on total mortality in patients with clinical heart failure and sinus rhythm.
- Conditions
- Arrhythmia, Cardiovascular Diseases, Heart Diseases, Heart Failure, Congestive
- Trial name
- NCT00000476
- Testing
- digitalis
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Psoriatic Arthritis, Osteoarthitis
CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry
CARTIZ is a prospective observational clinical registry of adults in Mexico receiving tirzepatide (a dual GLP-1/GIP receptor agonist) under an independent clinical indication - typically type 2 diabetes, insulin resistance…
- Conditions
- Psoriatic Arthritis, Osteoarthitis, Knee, Diabetes (DM)
- Trial name
- CARTIZ (NCT07567378)
- Testing
- Tirzepatide
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- JULIO GRANADOS MONTIEL
Pulmonary Hypertension
LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF
This study will evaluate the efficacy of TNX-103 (oral levosimendan) compared with placebo in subjects with PH-HFpEF as measured by the change in 6-Minute Walk Distance (6 MWD; Day 1 to Week 12).
- Trial name
- LEVEL (NCT05983250)
- Testing
- TNX-103
- Where
- 42 sites in United States, Canada
- Volunteers
- 230 people
- Sponsor
- Tenax Therapeutics, Inc.
Abdominal Aortic Aneurysm, Coronary Heart Disease
Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study
Specific cardiovascular diseases, such as stroke and heart attack, have been shown to vary by ethnic group. However, less is known about differences between ethnic groups and a wider range of cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease, Sudden Cardiac Death, Intracerebral Haemorrhage
- Trial name
- NCT02176174
- Volunteers
- 1,068,318 people, healthy volunteers welcome
- Sponsor
- University College, London
Heart Failure
Coping Skills and Heart Failure: Outcomes and Mechanisms
This study will evaluate whether heart failure patients receiving a 16 week telephone delivered, intervention using cognitive behavior therapy to facilitate self-management of heart failure will have better clinical outcomes than…
- Trial name
- COPE-HF (NCT00873418)
- Testing
- Coping skills training
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Duke University
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