Clinical trials: Heart Failure, Unspecified
Heart Failure
Evaluation of Automatic Threshold Algorithms
This study will evaluate the PaceSafe Right Ventricular Autothreshold (RVAT) and Left Ventricular Autothreshold (LVAT) features for AUTOGEN Cardiac Resynchronization Therapy Defibrillator (CRT-D) devices.
- Trial name
- CAPTIVATE (NCT02097290)
- Testing
- CRT-D
- Where
- 36 sites in United States
- Volunteers
- 216 people
- Sponsor
- Boston Scientific Corporation
Obstructive Sleep Apnea
Benefit of Cheyne-Stokes Respiration Remote Monitoring in CPAP-treated Patients With Obstructive Sleep Apnea to Detect Early Events of Heart Failure.
Obstructive sleep apnea (OSA) syndrome affects 40-60% of patients presenting with cardiovascular diseases. Cheyne-Stokes respiration is a type of central apnea characterised by the presence of at least three consecutive episodes…
- Trial name
- NCT03592108
- Testing
- CSR remote monitoring
- Where
- France
- Volunteers
- 555 people
- Sponsor
- Groupe Medical de Pneumologie, Polyclinique Saint-Laurent
Coronary Heart Disease, Heart Failure
Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 7.5 Years Follow-up
Since the introduction of antiretroviral therapy life expectancy of HIV-infected persons is rising. Different cohorts are observing an increased risk for cardiovascular diseases in this aging HIV-infected population.
- Conditions
- Coronary Heart Disease, Heart Failure, HIV, AIDS
- Trial name
- NCT01667068
- Testing
- Comprehensive non invasive cardiovascular examination
- Where
- 6 sites in Germany
- Volunteers
- 1,481 people
- Sponsor
- University Hospital, Essen
Heart
Kinesthetic Exercises on Adults
The aim of this study is to determine the possible effect of kinesthetic brain exercises on cognitive function in patients with heart failure.
- Trial name
- NCT07417748
- Testing
- Kinesthetic brain exercises, Cardiorespiratory Physiotherapy, Heart Failure drugs
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ege University
Advanced Heart Failure, Acquired Heart Disease
TORCH-LATAM-004: Regional Advanced-Therapy Pathways for Adults With Acquired or Structural Heart Disease
TORCH-LATAM-004 is a pragmatic stepped-wedge cluster randomized trial evaluating a regional pathway for adults with advanced heart failure secondary to acquired or structural heart disease who may require heart or combined…
- Conditions
- Advanced Heart Failure, Acquired Heart Disease, Structural Heart Disease, Heart Transplantation
- Trial name
- TORCH-004 (NCT07826078)
- Testing
- TORCH Adult Advanced Therapies Pathway (TORCH-AATP)
- Volunteers
- 360 people
- Sponsor
- CardioVision International Tech, S.A.S. de C.V.
Heart Failure
Heart Failure Optimization at Home to Improve Outcomes (Hozho): A Pragmatic Clinical Trial in Navajo Nation
Heart failure causes significant morbidity and mortality, particularly in Navajo Nation. There are well-established evidence of improved mortality and lower heart failure hospitalizations with certain pharmacotherapies for heart…
- Trial name
- Hozho (NCT05792085)
- Testing
- EHR-based GDMT Optimization
- Where
- 2 sites in United States
- Volunteers
- 103 people
- Sponsor
- University of Pennsylvania
COPD, Heart Failure
Personalized Experiences to Inform Improved Communication for Minorities With Life Limiting Illness
The purpose of this research is to develop patient-centered palliative care interventions to improve patient-provider communication and Quality of Life (QoL) of ethnic and racial minority patients living with life-limiting…
- Conditions
- COPD, Heart Failure, Cancer
- Trial name
- NCT03391115
- Testing
- Storytelling Intervention for Patient Participants, Storytelling Intervention for Nurse Participants
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Heart Failure (HF)
SchlaHF-XT-Register. Sleep Disordered Breathing in Heart Failure Register
The SchlaHF XT Registry is a longitudinal study of patients with heart failure (HF). The study aims to understand the importance of diagnosis and treatment of sleep disordered breathing (SDB) on HF with the following questions…
- Trial name
- NCT02301689
- Where
- Germany
- Volunteers
- 4,749 people
- Sponsor
- ResMed
Heart Failure NYHA Class I, Heart Failure NYHA Class II
Cycle Ergometer Training and Heart Failure on Heart Rate Recovery and Mind Fullness
To evaluate the effects of cycle ergometer training on heart rate recovery in Newyork Heart Association (NYHA) class I and II heart patients.
- Trial name
- NCT04741191
- Testing
- Cycle ergometer training, Conventional therapy
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Heart Failure, Left Bundle-Branch Block
Optimised MultiSite Pacing Vector Study
The objective of this clinical investigation is to evaluate the clinical benefits of an MultiSite pacing (MSP) with patient specific left ventricular vector optimization in patients receiving cardiac resynchronization therapy…
- Conditions
- Heart Failure, Left Bundle-Branch Block, Systolic Dysfunction
- Trial name
- NCT03938090
- Testing
- Optimised MultiSite Pacing, Standard biventricular pacing
- Where
- United Kingdom
- Sponsor
- Barts & The London NHS Trust
Heart Failure
Acorai Machine Learning Generalization (MLG) Study
Acorai is developing a non-invasive monitoring system for the estimation of intracardiac hemodynamic parameters in patients with suspected or confirmed heart failure, and/or pulmonary hypertension, who require hemodynamic…
- Trial name
- CAPTURE-HF (NCT05835024)
- Testing
- Acorai Sensor Data Collection (ASDC) system 1.0 - Phase 1, Acorai Sensor Data Collection (ASDC) system 1.0 - Phase 2
- Where
- 18 sites in United States, Belgium and 4 more
- Volunteers
- 1,602 people, healthy volunteers welcome
- Sponsor
- Acorai AB
Heart Failure, Congestive Heart Failure
Safety and Feasibility of the WhiteSwell System"
Early feasibility study to evaluate safety and performance of the WhiteSwell System in the treatment of fluid overload in hospitalized patients with acutely decompensated heart failure.
- Trial name
- SWIFTHF (NCT02863796)
- Testing
- WhiteSwell System
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- WhiteSwell, Limited
Heart Failure
BRING-UP 3 Heart Failure
The aim of this observational study is to assess the level of adherence to guideline recommendations regarding the management of patients with Heart Failure with Reduced Ejection Fraction (HFrEF); - the safety profile of the…
- Trial name
- BRING-UP3HF (NCT06279988)
- Where
- 187 sites in Italy
- Volunteers
- 10,000 people
- Sponsor
- Heart Care Foundation
Heart Failure, Left-Sided Heart Failure
CardioMEMS HF System Post Approval Study
The purpose of the CardioMEMS HF System Post Approval Study (PAS) is to evaluate the use of the CardioMEMS HF System in patients with NYHA class III heart failure in a commercial setting.
- Conditions
- Heart Failure, Left-Sided Heart Failure, Congestive Heart Failure
- Trial name
- NCT02279888
- Testing
- CardioMEMS HF System
- Where
- United States
- Volunteers
- 1,214 people
- Sponsor
- Abbott Medical Devices
Cardiovascular Diseases, Coronary Disease
Dobutamine Echocardiography In Patients With Ischemic Heart Failure Evaluated for Revascularization
To define the role of the assessment of myocardial viability with dobutamine echocardiography (DE) in the clinical evaluation and selection of the best treatment for a high-risk subset of patients with coronary artery disease.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Failure, Heart Failure, Congestive
- Trial name
- DECIPHER (NCT00074724)
- Testing
- Coronary Artery Bypass, Modern medical management, Dobutamine echocardiography
- Volunteers
- 319 people
- Sponsor
- Medstar Health Research Institute
Heart Failure, Hyperuricemia
Long-term Prednisone Use for End-stage Heart Failure
Patients with advanced (ACCF/AHA stage D) heart failure and hyperuricemia have high one-year mortality. Currently, there was no evidence-based therapy such as mechanically assisted circulatory support available in China.
- Trial name
- NCT02282683
- Testing
- prednisone
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Hebei Medical University
Heart Failure
Impact of Interval Training on Sympathetic Hyperactivity and Vascular Function
In this study, the investigators are testing the hypothesis that reduction in sympathetic activity would be greater following high-intensity interval training (HIIT) than moderate-intensity continuous training (MICT) and…
- Trial name
- NCT04248894
- Testing
- Exercise training of High Intensity, Exercise training of Moderate Intensity, Untraining
- Where
- 2 sites in Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo General Hospital
Heart Failure, Chronic Kidney Diseases
DKK3 for Prognosis and Monitoring of GFR Decline in Heart Failure
The individual course of chronic kidney disease (CKD) may vary, and improved methods for identifying which patients will experience estimated glomerular filtration rate (eGFR) decline are needed.
- Trial name
- NCT04111094
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 290 people
- Sponsor
- University of Giessen
Chronic Heart Failure, Iron Deficiency, Latent
The Prevalence of Iron Deficiency and the Effectiveness of Ferinject® in Patients With HFpEF (ID-HFpEF)
Observational cohort randomized controlled study to study the influence of correction of ID by intravenous injection of ferric carboxymaltose (Ferinject®) on quality of life indicators, functional status in a cohort of patients…
- Trial name
- ID-HFpEF (NCT05793996)
- Testing
- Ferinject, Diet therapy
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Heart Failure, Medication Optimization
Optimizing Heart Failure Therapies Among Patients With Limited Access in Denver
Numerous pharmacotherapies have been proven to reduce mortality and hospitalization rates for heart failure with reduced ejection fraction (HFrEF) patients.
- Trial name
- NCT07435662
- Testing
- Pharmacy follow up
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Denver Health and Hospital Authority
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