Clinical trials: Heart Infarction
ACS - Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI
MCG Discovery Study in Emergency Departments
This prospective discovery study is designed to demonstrate the feasibility of using an unshielded, mobile MCG device in an Emergency Department (ED) setting.
- Trial name
- NCT06095557
- Testing
- Sponsor MCG device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- SB Technology, Inc.
Coronary Artery Disease With Myocardial Infarction
Comparison of 2 Hemostasis Techniques After Transradial Coronary
Randomized clinical trial to compare radial artery patency after transradial coronary catheterization using 2 different hemostasis techniques.
- Trial name
- NCT02873871
- Testing
- Standardized compressive dressing, Hemostasis with TerumoBand®
- Where
- Brazil
- Volunteers
- 600 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Arrythmia -Myocardial Infarction
Identification of Risk Factors for the Occurrence of High-grade Rhythm Disorders in Patients With ST-segment Elevation Myocardial Infarction (STEMI)
The goal of this study is to identify the risk factors for the occurrence of arrythmia in patient with stemi in prehospital management.
- Trial name
- STEMI (NCT05040919)
- Testing
- collection of medical and socio-demographic data
- Where
- France
- Volunteers
- 652 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Acute Myocardial Infarction (AMI)
Effectiveness of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitor Initiation Before Percutaneous Coronary Intervention on Acute Myocardial Infarction Patients
The goal of this clinical trial is to learn if drug tafolecimab works to treat participants with acute myocardial infarction (AMI) scheduled for primary percutaneous coronary intervention (PCI).
- Trial name
- IMPROVE-AMI (NCT06683131)
- Testing
- Tafolecimab
- Where
- 13 sites in China
- Volunteers
- 1,160 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
ST-segment Elevation Myocardial Infarction (STEMI)
EARLY-MYO-CMR Registry
The purpose of this registry is to depict the myocardial tissue characteristics in STEMI patients by CMR and other cardiac imaging modalities and to assess the prognostic value of imaging-derived indices.
- Trial name
- NCT03768453
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- RenJi Hospital
Acute Coronary Syndrome
Veliflapon (DG-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina
The purpose of this study is to determine if veliflapon (DG-031)can prevent a heart attack or stroke in African American patients with a history of unstable angina or myocardial infarction.
- Trial name
- NCT00353067
- Testing
- veliflapon (DG-031)
- Where
- 11 sites in United States
- Volunteers
- 3,450 people
- Sponsor
- deCODE genetics
Myocardial Infarction
Stem Cell Therapy to Improve Myocardial Function in Patients With Acute Myocardial Infarction
The purpose of the study is to compare the efficiency of a sorted subpopulation of CD34+/CXCR4+ cells and unselected bone marrow-derived progenitor cells in the treatment of patients with acute myocardial infarction and a low…
- Trial name
- NCT00316381
- Testing
- Autologous bone marrow-derived stem cells
- Where
- 4 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Silesian School of Medicine
Acute Myocardial Infarction
Nationwide Trends in Incidence, Healthcare Utilization, and Mortality in Hospitalized Acute Myocardial Infarction Patients in Taiwan
This was a retrospective study using the Taiwan's National Health Insurance Research Database (NHIRD). The study employed two study designs for different purposes as follows: A cross-sectional analysis was conducted to explore…
- Trial name
- NCT05974397
- Where
- Taiwan
- Volunteers
- 124,018 people
- Sponsor
- Novartis Pharmaceuticals
Myocardial Infarction (MI)
Contribution of Myocardial Perfusion Imaging in the Initial Assessment of Acute Coronary Syndromes Without ST Elevation for the Diagnosis of Myocardial Infarction or Differential Diagnoses
Patients with myocardial infarction require invasive treatment involving coronary angiography to confirm the diagnosis and, in most cases, treatment by angioplasty/stenting.
- Trial name
- APRICOT (NCT07112820)
- Testing
- perfusion ultrasound
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Aortic Stenosis, Chemotherapy Induced Systolic Dysfunction
Fibrosis in Chronic and Delayed Myocardial Infarction
In this study the investigators aim to examine the role that fibrosis plays in heart conditions such as aortic stenosis , chemotherapy-induced cardiotoxicity and carcinoid syndrome .
- Conditions
- Aortic Stenosis, Chemotherapy Induced Systolic Dysfunction, Carcinoid Syndrome
- Trial name
- FCDMI (NCT05756608)
- Testing
- 68Ga-FAPI and 18F-AlF-FAPI PET-MR
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Coronary Artery Disease
Personal Genomics for Preventive Cardiology
The purpose of this study is to see if providing information to a person on their inherited (genetic) risk of cardiovascular disease (CVD) helps to motivate that person to change their diet, lifestyle or medication regimen to…
- Trial name
- NCT01406808
- Testing
- genetic risk score for coronary risk factors
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myocardial Infarction Postoperative, Myocardial Injury
Myocardial Infarction in the Perioperative Setting
Acute myocardial infarction (AMI) is a significant complication following non-cardiac surgery. The investigators sought to evaluate incidence of perioperative AMI, its preoperative and intraoperative risk factors and the outcomes…
- Conditions
- Myocardial Infarction Postoperative, Myocardial Injury, Intraoperative Complications, Intraoperative Hypotension
- Trial name
- MIPS (NCT03837535)
- Testing
- Surgery
- Where
- Sweden
- Volunteers
- 400,742 people
- Sponsor
- Karolinska University Hospital
Acute Coronary Syndrome
Characteristics and Consequences of Coronary Angiograms Performed in Intensive Care Patients
Coronary angiography is a key examination in the management of many patients hospitalized in intensive care units. The most frequent indication remains the performance of a gesture of unblocking of part of the coronary network in…
- Trial name
- Coro-ICU (NCT05529810)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Atrial Fibrillation, Stroke
Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
Demonstrating the pathophysiological link between Left Atrial (LA) and Left Atrial Appendage (LAA) pathology and embolic strokes in non-Atrial Fibrillation (AF) individuals represents a major advance in stroke prevention…
- Conditions
- Atrial Fibrillation, Stroke, Stroke, Cardiovascular, Vascular Cognitive Impairment
- Trial name
- NCT04769310
- Testing
- Cardiac and Brain MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Tulane University
STEMI - ST Elevation Myocardial Infarction
Century Clot-Guided Prophylactic Rivaroxaban for Post STEMI Complicating Left Ventricular Thrombus
To manage the ST-segment elevation myocardial infarction (STEMI) caused by plaque rupture, triggers platelet activation/aggregation and thrombin generation, requires dual (platelet and coagulation) pathway inhibition.
- Trial name
- NCT06013020
- Testing
- NOAC+DAPT, DAPT
- Where
- China
- Volunteers
- 374 people
- Sponsor
- Zunyi Medical College
Myocardial Infarction, Coronary Artery Disease
A Randomized Evaluation of First-dollar Coverage for Post-MI Secondary Preventive Therapies
The objective of this randomized trial is to evaluate the effect of providing full prescription drug coverage (i.e. no co-pays, co-insurance or deductibles) for statins, beta-blockers, angiotensin converting enzyme inhibitors and…
- Trial name
- MI FREEE (NCT00566774)
- Testing
- Full drug coverage, Usual coverage
- Where
- United States
- Volunteers
- 5,860 people
- Sponsor
- Brigham and Women's Hospital
Myocardial Infarction (MI), Cardiac Rehabilitation
Eccentric Exercise Rehabilitation After Myocardial Infarction
This clinical trial will evaluate a two-week eccentric exercise program conducted as part of comprehensive cardiac rehabilitation in patients after a heart attack (myocardial infarction).
- Trial name
- ECCENTRIC-MI (NCT07729410)
- Testing
- Standard Inpatient Cardiac Rehabilitation, Eccentric Cycling Exercise
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Ventricular Tachycardia, Myocardial Infarction
Cardiac Radioablation for VT
The goal of this interventional study is to determine the minimum dose necessary for successful cardiac radioablation of refractory ventricular tachycardia (VT) and to study the utility of target volume definition using Delayed…
- Trial name
- NCT06593418
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Corewell Health East
Cardiogenic Shock, Peripartum Cardiomyopathy
"Treatment Use of ECMO In Pregnancy or Peripartum Patient."
The goal of this study is to describe the use of ECMO (Extracorporeal Membrane Oxygenation) in the pregnant or peripartum patient.
- Conditions
- Cardiogenic Shock, Peripartum Cardiomyopathy, Complication, Pregnancy
- Trial name
- NCT04144660
- Testing
- Extracorporeal Membrane Oxygenation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Sarah Thordsen
Myocardial Infarction
Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevation Myocardial Infarction (STEMI) Patients
Several recent trials (1,2) suggest that all STEMI patients receiving fibrinolysis in non-PCI centres should be routinely transferred for elective early PCI within 24 hours from hospitalization, with no additive risk of major…
- Trial name
- NCT01014182
- Where
- United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
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