Clinical trials: Heart Infarction
Acute ST Elevation Myocardial Infarction
Nitrites in Acute Myocardial Infarction
The research question to be addressed is "Does a 2.5 - 5 minute systemic intravenous injection of sodium nitrite administered immediately before opening of the infarct related artery result in significant reduction of ischaemia…
- Trial name
- NIAMI (NCT01388504)
- Testing
- sodium nitrite
- Where
- 3 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Aberdeen
Acute Myocardial Infarction, Women Over 18 and Under 50 Years of Age
WAMIF : Young Women Presenting Acute Myocardial Infarction in France
MI in elderly women seems to share the same pathophysiology than in men, especially plaque rupture associated with conventional risk factors.
- Trial name
- WAMIF (NCT03073447)
- Testing
- Specific blood sample of women under 50 years with acute MI
- Where
- 29 sites in France
- Volunteers
- 324 people
- Sponsor
- French Cardiology Society
Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Acute Coronary Syndromes (ACS)
Occurrence of Severe Cardiac Rhythm and Conduction Disturbances in Emergency Department Patients With Non-ST Elevation Acute Coronary Syndrome
Cardiovascular diseases are the leading cause of death worldwide. Among them, coronary artery disease-especially in its acute form, known as acute coronary syndrome (ACS)-is the most frequent cause of cardiovascular death.
- Conditions
- Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Acute Coronary Syndromes (ACS), Myocardial Infarction, Unstable Angina Pectoris, Sudden Cardiac Death, Stroke, Peripheral Artery Disease
- Trial name
- SurvSCA (NCT07112547)
- Where
- 10 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Coronary Artery Disease With Myocardial Infarction
Korean NIRS-IVUS Multicenter Registry
Heart diseases known as the second cause of death in Koreans are coronary artery diseases such as angina and myocardial infarction. Coronary artery disease occurs when fat components, such as cholesterol, accumulate in the body.
- Trial name
- NCT04619355
- Testing
- NIRS-IVUS
- Where
- South Korea
- Volunteers
- 1,500 people
- Sponsor
- Korea University Anam Hospital
Myocardial Infarction
Multimodality Cardiovascular Imaging for the Translation of Therapies for Vascular Activation After MI
Subjects with urgently reperfused type I myocardial infarction (MI) will be recruited and randomized to receive either placebo or the oral inflammasome (NLRP3) inhibitor dapansutrile.
- Trial name
- NCT05880355
- Testing
- Dapansutrile
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Virginia
Atrial Fibrillation, Myocardial Infarction
Triple or Dual Antithrombotic Therapy After PCI (TRIDUAL-PCI) Coronary Intervention in Patients With Non-valvular Atrial Fibrillation. Real-world Italian Multicenter Registry (TRIDUAL-PCI)
Aim of this study is to describe clinical and procedural characteristics of real-world population initiated on triple antithrombotic therapy (double antiplatelet therapy+anticoagulant) or double antithrombotic therapy (single…
- Conditions
- Atrial Fibrillation, Myocardial Infarction, Anticoagulant-induced Bleeding, Coronary Disease
- Trial name
- TRIDUAL-PCI (NCT04291287)
- Testing
- Antithrombotic Agent
- Where
- Italy
- Volunteers
- 1,500 people
- Sponsor
- Scientific Institute San Raffaele
Acute Myocardial Infarction (AMI)
Artificial Intelligence Scalable Solution for ST Myocardial Infarction
The ASSIST clinical study is an observational, multicenter study to assess the performance of a cloud-based and AI-powered electrocardiogram (ECG) analysis platform, named Willem™, developed to detect Acute Myocardial Infarction…
- Trial name
- ASSIST (NCT06939738)
- Where
- 5 sites in Portugal, Spain
- Volunteers
- 489 people
- Sponsor
- Idoven 1903 S.L.
Myocardial Infarction, Angina
An Observational Study of Cholesterol in Coronary Arteries
In April 2008, a coronary catheter based imaging system, LipiScan, was cleared by the FDA for use in detecting lipid core containing containing plaques of interest (LCP). These plaques are rich in cholesterol.
- Conditions
- Myocardial Infarction, Angina, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- COLOR (NCT00831116)
- Testing
- Intravascular Near Infrared Spectroscopy
- Where
- 22 sites in United States
- Volunteers
- 2,067 people
- Sponsor
- Infraredx
Myocardial Bridge of Coronary Artery, Myocardial Bridge
Myocardialbridge Bypass Graft Surgery Efficacy Verification
Myocardial Bridge Bypass Graft surgery is introduced to relieve the unmedical symptoms of patients with long-segment or deep myocardial bridge, clinical outcomes will be collected to verify the effectiveness of the surgery.
- Conditions
- Myocardial Bridge of Coronary Artery, Myocardial Bridge, Myocardial Bridging, Myocardial Infarction
- Trial name
- NCT06857838
- Testing
- MBBG, MB CABG, MB unroof
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xi'an International Medical Center Hospital
ST Segment Elevation Myocardial Infarction
Italian Multi-center Registry of Self-apposing Coronary Stent in Patients With STEMI
The aim of this registry is to collect clinical data on nitinol self-expanding STENTYS Xposition S™ in order to evaluate the efficacy and safety in patients presenting with ST segment elevation myocardial infarction
- Trial name
- iPOSITION (NCT02979236)
- Testing
- STENTYS Xposition S
- Where
- 8 sites in Italy
- Volunteers
- 250 people
- Sponsor
- UOSD Emodinamica Diagnostica e Interventistica
Myocardial Infarction
CARESS in Acute Myocardial Infarction
The aim of this study conducted in patients with high risk ST-segment elevation AMI admitted to hospitals with no PTCA facilities is to compare the effects on clinical outcome and cost-effectiveness of two reperfusion strategies…
- Trial name
- NCT00220571
- Testing
- Coronary Angioplasty (PTCA)
- Where
- 85 sites in France, Italy and 1 more
- Volunteers
- 600 people
- Sponsor
- Società Italiana di Cardiologia Invasiva
ST Elevation Myocardial Infarction, Colchicine
Effect of Colchicine on MMP-9, NOX2, and TGF-β1 in Myocardial Infarct
Reducing NOX-2, MMP-9, and TGF-β1 Expression in Preventing Ventricular Remodelling Post Acute ST-Segment Elevation Myocardial Infarction using Colchicine (Post Late Reperfusion Percutaneous Coronary Intervention and…
- Conditions
- ST Elevation Myocardial Infarction, Colchicine, Cardiac Remodeling, Ventricular
- Trial name
- NCT05709509
- Testing
- Colchicine, Percutaneous Coronary Intervention, Optimal medical treatment including statin, aspirin, P2Y12 inhibitor, and nitrate.
- Where
- Indonesia
- Volunteers
- 148 people
- Sponsor
- RSD dr. Soebandi
Coronary Arteriosclerosis, Myocardial Infarction
Radial Artery Bypass Graft Study of Tromsø
The purpose of this study is to answer, among others, the following questions: 1) What are the outcomes when using the radial artery as a bypass graft in coronary artery bypass surgery (CABG)? 2) Can multidetector computed…
- Trial name
- NCT00113451
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University Hospital of North Norway
Acute ST Segment Elevation Myocardial Infarction
Study to Evaluate the Effect on Parameters of Systemic Inflammation and Disease Outcomes and Safety of RPH-104 in Subjects With Acute ST-elevation Myocardial Infarction
The goal of the study was to evaluate the effect of single administration of RPH-104 at 80 mg and 160 mg on parameters of systemic inflammation and outcomes of the disease in subjects with ST-segment elevation myocardial…
- Trial name
- NCT04463251
- Testing
- RPH-104 80 mg
- Where
- 11 sites in United States, Russia
- Volunteers
- 102 people
- Sponsor
- R-Pharm Overseas, Inc.
NSTEMI
Incidence of Occluded Culprit Arteries and Impact of Coronary Collaterals on Outcome in Patients With NSTEMI
It is assumed that patients with non-ST-elevation myocardial infarctions (NSTEMI) showing an infero- or posterolateral occluded culprit artery (OCA) during diagnostic angiography frequently elude standard 12-lead…
- Trial name
- NCT01159366
- Testing
- percutaneous coronary intervention
- Where
- Germany
- Volunteers
- 602 people
- Sponsor
- University of Jena
NSTEMI - Non-ST Segment Elevation MI, Unstable Angina
A Multicenter Study on Early Diagnosis of NSTE-ACS Patients Based on Machine Learning Model
Early diagnosis of NSTEMI and UA patients is mainly through the construction of machine learning model.
- Trial name
- NCT04682756
- Testing
- The model of machine learning
- Where
- China
- Volunteers
- 2,500 people
- Sponsor
- First Affiliated Hospital of Xinjiang Medical University
Coronary Heart Disease
The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and Diabetes
In this study, simvastatin combined with Ezeimebum was used to enhance lipid reduction, and IVUS was used to evaluate the volume and composition of coronary plaque before and after treatment.
- Trial name
- NCT03771053
- Testing
- Ezetimibe with simvastatin, Simvastatin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Chinese PLA General Hospital
Coronary Heart Disease, Stroke
The Copenhagen City Heart Study
The Copenhagen City Heart Study is an ongoing cardiovascular population study initiated in 1976 which has examined approximately 25,000 individuals from the general population.
- Conditions
- Coronary Heart Disease, Stroke, Heart Failure, Cancer
- Trial name
- CCHS (NCT02993172)
- Volunteers
- 23,891 people
- Sponsor
- Bispebjerg Hospital
Myocardial Infarction, Fibrosis
Angiogenesis and Fibrosis in Myocardial Infarction
Angiogenesis and fibrosis lie at the heart of a number of fundamental processes responsible for cardiovascular disease. In this proposal, the investigators intend to build upon a highly successful programme of studies exploring…
- Conditions
- Myocardial Infarction, Fibrosis, Neovascularization, Pathologic
- Trial name
- NCT01813045
- Testing
- Cardiac MRI scan, CT-PET scan, CT-coronary angiogram
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
Acute Myocardial Infarction
Evaluate the Safety and Explore Efficacy of Umbilical Cord Mesenchymal Stem Cells in Acute Myocardial Infarction
This study is a first-in-human assessment of safety of using UCMSC in patients with AMI via a combination of IC and IV stem cell administration.
- Trial name
- NCT04056819
- Testing
- Allogeneic umbilical cord mesenchymal stem cells
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Ever Supreme Bio Technology Co., Ltd.