Clinical trials: Heart Rate Fast
Long QT Syndrome, Sudden Cardiac Death
Electromechanical Profiling of the Long-QT Syndrome (LQTS)
High-resolution, non-invasive electromechanical mapping in genotyped long-QT syndrome patients and healthy controls at baseline and during smart provocation.
- Conditions
- Long QT Syndrome, Sudden Cardiac Death, Ventricular Tachycardia
- Trial name
- EMLoQ (NCT04074122)
- Testing
- Adenosine and epinephrine, isoprenaline provocation
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Postural Orthostatic Tachycardia Syndrome, Hypocapnia
Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia
Postural tachycardia syndrome (POTS) is the most common chronic cause of postural lightheadedness, and upright confusion afflicting many Americans, mostly young women.
- Conditions
- Postural Orthostatic Tachycardia Syndrome, Hypocapnia, Hyperventilation
- Trial name
- NCT05923840
- Testing
- Chemoreflex Testing, Baroreflex testing, Orthostatic stress testing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Arrhythmias, Cardiac
Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic
Biorepository of blood and or tissue samples from patients presenting with cardiac arrhythmia syndromes.
- Trial name
- NCT00921986
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Ventricular Tachycardia
Anesthetic Management in Patients Undergoing Epicardial Ablation
The study is a retrospective study and is descriptive in nature. In this study, the investigators aimed to emphasize the importance of anesthesia management by cardiac risk assessment of patients undergoing epicardial ablation…
- Trial name
- NCT06538987
- Testing
- percutaneous epicardial ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Abdominal Pain
Heart Rate Variability in Children With a Functional Gastrointestinal Disorder
The current study is designed to assess relationships between anxiety/stress, autonomic nervous system balance, and electrical activity in the stomach before and after eating/drinking in children with abdominal pain.
- Trial name
- NCT00195975
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Postural Tachycardia Syndrome
fMRI in Postural Tachycardia Syndrome
Postural tachycardia syndrome (POTS) is one of the most common forms of chronic orthostatic intolerance in the United States. This is a disabling disorder characterized by an excessive increase in heart rate upon standing that is…
- Trial name
- POTS (NCT04137757)
- Testing
- Lower Body Negative Pressure
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autonomic Failure, Dysautonomia
Concentration and Attentional Deficits in POTS and Other Autonomic Neuropathies
People with POTS, autoimmune autonomic neuropathy (AAN), pure autonomic failure (PAF), SFN and Ehlers Danlos Syndrome (EDS) do not only suffer from orthostatic symptoms such as dizziness, headache, neck pain, blurred vision or…
- Conditions
- Autonomic Failure, Dysautonomia, Cognitive Impairment, Ehlers-Danlos Syndrome
- Trial name
- POTSKog (NCT03681080)
- Testing
- leg crossing
- Where
- Germany
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Torsades de Pointes
A Study to Evaluate How VI-0521 Affect Cardiac Repolarization in Healthy Male and Female Volunteers
Determine whether VI-0521 has an effect on the electrical activity of the heart in healthy subjects. Find out how much VI-0521 is in the blood and any potential side effects on ECG's of healthy subjects after taking the study…
- Trial name
- TQT (NCT00839891)
- Testing
- VI-0521
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Postural Tachycardia Syndrome, Orthostatic Intolerance
Peripheral Dopamine in Postural Tachycardia Syndrome
The purpose of the proposed research is to determine how changes in kidney dopamine (DA) activity influence urinary sodium excretion.
- Trial name
- NCT00685919
- Testing
- Carbidopa
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Ventricular Tachycardia
Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS)
Medtronic is sponsoring the Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS) to further confirm safety and effectiveness of ventricular iATP therapy in routine clinical practice, following commercial release of…
- Trial name
- NCT04496518
- Testing
- Intrinsic Antitachycardia Pacing (iATP) Therapy
- Where
- 92 sites in United States, France and 7 more
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Medtronic
Postural Orthostatic Tachycardia Syndrome, Postural Tachycardia Syndrome
Autoimmune Basis for Postural Tachycardia Syndrome
The purpose of this study is to see if some people with postural tachycardia syndrome (POTS) have higher levels of immune proteins (autoantibodies) directed against receptors of the autonomic nervous system, and if these…
- Conditions
- Postural Orthostatic Tachycardia Syndrome, Postural Tachycardia Syndrome, Tachycardia, Arrhythmias, Cardiac
- Trial name
- NCT02725060
- Testing
- phenylephrine, isoproterenol, 25 micro-Ci of radiation
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
HRV, Psychological Adaptation
Weight Cut Stress: the Hidden Struggle Beyond Fight Day
This study investigated the effects of rapid weight-cutting on stress in elite kickboxers by analyzing Heart Rate Variability (HRV) and subjective stress levels using a Visual Analog Scale (VAS).
- Trial name
- NCT06860204
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Postural Orthostatic Tachycardia Syndrome
Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)
This is an observational study to deeply phenotype the disorder of POTS using multiple testing modalities.
- Trial name
- NCT06292104
- Testing
- multimodal diagnostic testing
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Fever, Heart Rate, Fetal (FHR)
Acetaminophen for Fetal Tachycardia: a Randomized Pilot Trial
The most common cause of fetal tachycardia is maternal fever. Fetal tachycardia often precedes the maternal fever, and fetal tachycardia confounds the interpretation of electronic fetal monitoring (EFM), increasing the rate of…
- Trial name
- NCT00377832
- Testing
- Acetaminophen 975 mg
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Postural Orthostatic Tachycardia Syndrome (POTS), Fibromyalgia (FM)
Auto-immune Contribution in Symptom-based Sensory and Autonomic Disorders
Postural Orthostatic Tachycardia Syndrome (PoTS) is a condition where the heart rate increases when standing up, causing symptoms like dizziness and fainting.
- Trial name
- ACSSAD (NCT06992531)
- Testing
- Questionnaire and Physical Exam, Nerve conduction studies, Microneurography
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- King's College London
Arrhythmias, Cardiac, Atrial Fibrillation
Clinical Cohort Study - TRUST
The "Long-term Outcome and Predictors for Recurrence after Medical and Interventional Treatment of Arrhythmias at the University Heart Center Hamburg" (TRUST) study is an investor-initiated, single-center, prospective clinical…
- Conditions
- Arrhythmias, Cardiac, Atrial Fibrillation, Atrial Flutter, Ventricular Tachycardia
- Trial name
- TRUST (NCT05521451)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Postural Tachycardia Syndrome
Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
This study is being conducted to see how people with Postural tachycardia syndrome (POTS) make sense of the things they see. The information may help doctors to learn more about how the different parts of people's brains…
- Trial name
- NCT05618054
- Testing
- Looming task
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Syncope
Evaluation of Chronic Orthostatic Intolerance
This study will conduct tests with patients with primary chronic orthostatic intolerance (COI) to learn more about this disorder of the autonomic nervous system.
- Trial name
- NCT00069693
- Where
- 3 sites in United States, Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tachycardia, Postural Orthostatic Tachycardia Syndrome
Pathophysiology of Orthostatic Intolerance
The purpose of this study is to describe the mechanism of orthostatic intolerance, relying on cardiovascular physiological studies.
- Trial name
- NCT00608725
- Testing
- DAXOR, QSweat, Intrinsic Heart Rate
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Satish R. Raj
Postural Orthostatic Tachycardia Syndrome (POTS), Healthy
POTS-FLOW: Interplay Between Gut Hormones and Autonomic Postprandial Blood Flow Regulation in Patients With POTS
This study will describe the interplay between the gut hormones GIP and CCK and their regulation of blood flow to the large vessels in patients with Postural Orthostatic Tachycardia Syndrome (POTS) and GIP, CCK and GLP-1 in…
- Trial name
- GA22 (NCT07019519)
- Testing
- GIPR antagonist, GLP-1R antagonist, CCK agonist
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen