Clinical trials: Heart Rate Variability (ANS Function)
Obstructive Sleep Apnea
Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea
The purpose of this study is to determine if vitamin D supplement and SGLT-2 inhibitor treatment combination can improve cardiovascular risks in patients with OSA and hypertension, on top of lifestyle modification, before…
- Trial name
- D3DOSA (NCT06690723)
- Testing
- Dapagliflozin (Forxiga), Vitamin D3 ( Colecalciferol), Vitamin D3 plus Dapagliflozin
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- University Malaysia Sarawak
Healthy, Swimming
EFFECTS OF FOAM ROLLING ON HRV IN ELITE SWIMMERS
The present study aimed to evaluate the effects of foam rolling (FR) on recovery by examining selected time-domain and frequency-domain heart rate variability (HRV) parameters in elite swimmers following intensive interval sprint…
- Conditions
- Healthy, Swimming, Autonomic Nervous System Function, Recovery
- Trial name
- HRV-SWIMMING (NCT07641062)
- Testing
- Swimming+FoamRollingRecovery, SwimmingRecovery
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Uludag University
Resistant Hypertension, Medication Adherence
Heart Rate Variability and Medication Adherence in Resistant Hypertension
This single-center, cross-sectional observational study examines the relationship between adherence to antihypertensive therapy - verified objectively by therapeutic drug monitoring (TDM) - and heart rate variability (HRV) in…
- Conditions
- Resistant Hypertension, Medication Adherence, Autonomic Nervous System
- Trial name
- HRV-HYP-1 (NCT07707583)
- Testing
- Heart rate variability recording (Polar H10) ·, Therapeutic drug monitoring (antihypertensive drug levels), Questionnaires (MARS-CZ, PHQ-9, SF-36, IPAQ)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Atopic Dermatitis
Comprehensive Investigation of Heart Rate Variability as a Measure of the Autonomic Nervous System in Atopic Dermatitis
The purpose of this research is to study heart rate patterns in people with moderate to severe atopic dermatitis and how itching affects those patterns.
- Trial name
- NCT00691366
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Coronary Artery Disease
AI ANC Headphones in Rotational Atherectomy
Background: Rotational atherectomy (RA) generates high-intensity drilling noise concentrated around 3000 Hz, creating a distinctive auditory stressor that may exacerbate perioperative anxiety and autonomic dysregulation in…
- Trial name
- ANC-RA (NCT07707843)
- Testing
- AI-Powered Active Noise-Cancelling Headphones (Sony WH-1000XM6)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University
Posttraumatic Stress Disorder (PTSD), Depression - Major Depressive Disorder
To Investigate the Change of Brain and Autonomic Function From Different Protocols of Repeated Transcranial Magnetic Stimulation Therapy for Patients With Post-traumatic Stress Disorder Comorbid Major Depressive Disorder
This study aims to investigate the immediate neurophysiological and autonomic effects of two noninvasive brain stimulation protocols-prolonged intermittent theta-burst stimulation (prolonged iTBS) and high-frequency repetitive…
- Trial name
- NCT07327385
- Testing
- Prolonged Intermittent Theta-Burst Stimulation (prolonged iTBS), High-Frequency Repetitive Transcranial Magnetic Stimulation (HF-rTMS)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Healthy
Cardiac Autonomic Functions During Head-out Immersion and During Head Down Tilt
Head down tilt (HDT) was widely used to simulate microgravity effects on cardiovascular system. HDT could be a suitable model of water immersion (WI) which is also used to simulate the cardiovascular effects of microgravity and…
- Trial name
- IMMERSION (NCT00515645)
- Testing
- Head-down tilt and immersion
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Functional Neurological Disorder
Clinical Evaluation of HRV Biofeedback in Functional Neurological Disorders Compared to Placebo
Evaluation of the clinical effects of the Heart Rate Variability biofeedback training with patients suffering from Functional neurological Disorders compared with placebo.
- Trial name
- HRV_BFB_FND (NCT06422819)
- Testing
- Heart rate variability Biofeedback [HRV-BFB], Pseudo HRV-BFB
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Urinary Bladder, Overactive
The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled Trial
The optimal medication for women with nocturia remains uncertain. This clinical trial aimed to determine the most effective medication for women with overactive bladder and nocturia.
- Trial name
- NCT07114640
- Testing
- Mirabegron 25mg, Solifenacin 5 mg, Tolterodine 4 mg
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Far Eastern Memorial Hospital
Long COVID, Heart Rate Variability (HRV)
Effects os Physiotherapeutic Rehabilitation on Function Autonomic and Inflammatory in Patients With Long Covid
Introduction: Long COVID is characterized by persistent symptoms that persist for weeks or months after the acute phase of infection, with a significant impact on the cardiovascular and autonomic systems.
- Conditions
- Long COVID, Heart Rate Variability (HRV), Cardiac Biomarkers, Inflammatory Biomarkers
- Trial name
- LongCovidRehab (NCT07046208)
- Testing
- physiothreapy protocol
- Volunteers
- 58 people
- Sponsor
- Universidade do Estado do Pará
BPPV, Stress and Anxiety
Heart Rate Variability in Benign Paroxysmal Positional Vertigo
Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular disorder. Although the pathophysiology of BPPV is mainly attributed to the displacement of otoconia within the semicircular canals, recent…
- Trial name
- BPPV-HRV (NCT07472998)
- Testing
- Short-term HRV measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Diabetes Mellitus, Autonomic Diseases
Glycemic Responses and of the Autonomic Cardiac Function in Diabetes Type-2 Women Post Resistance Exercise
The aim of this study was to investigate and correlate the glucose responses and VFC 24 hours after resistance exercise (RE) sessions at different intensities in women with type 2 diabetes (DM-2).
- Trial name
- NCT02645448
- Testing
- Resistance Exercise
- Volunteers
- 12 people
- Sponsor
- Universidade Federal do vale do São Francisco
Post-Concussion Syndrome
Post-concussion Syndrome and Chiropractic
This proof-of-concept trial will explore the effects of manual chiropractic adjustments on nervous system function in individuals with post-concussion syndrome.
- Trial name
- PCS (NCT06151184)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Life University
Major Depressive Disorder
Intradermal Acupuncture as an Adjunct to SSRI Tapering in Major Depressive Disorder
This randomized controlled trial aims to evaluate the clinical efficacy of intradermal acupuncture as an adjunctive intervention to assist selective serotonin reuptake inhibitor (SSRI) dose reduction or discontinuation in adult…
- Trial name
- NCT07390981
- Testing
- Selective Serotonin Reuptake Inhibitors (SSRIs), Intradermal Acupuncture
- Volunteers
- 114 people
- Sponsor
- First People's Hospital of Hangzhou
Phototherapy, Autonomic Nervous System
Effects of Phototherapy Associated With Sprint and Squat Training on Cardiac Autonomic Modulation
Recent studies have shown positive results in the application of phototherapy for the improvement of performance and acceleration of the healing process of the body homeostasis.
- Conditions
- Phototherapy, Autonomic Nervous System, Training
- Trial name
- NCT03566186
- Testing
- Phototherapy, Passive recovery
- Where
- Brazil
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Paulista University
Improvement of Functional Capacity., Improvement of Quality of Life.
Effect of a Program of Deep Inspiration Combined to Expiratory Positive Airway Pressure in Asthmatic
The purpose of this study is to determine the effects of a deep inspiration combined to expiratory positive airway pressure protocol on respiratory function, quality of life, exercise tolerance and heart rate variability in…
- Conditions
- Improvement of Functional Capacity., Improvement of Quality of Life., Improvement of Cardiovascular Autonomic Control.
- Trial name
- NCT01643421
- Testing
- Deep inspiration and positive expiratory airway pressure
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities
Electrocardiographic Autonomic Function Measures in Mechanically Ventilated Patients
This research proposal has two main objectives. The first is to increase understanding of the underlying physiological interactions that occur between the cardiovascular, pulmonary, and ANS during transition between positive…
- Conditions
- Disorders of the Autonomic Nervous System, Cardiovascular Abnormalities, Respiratory Disorders
- Trial name
- NCT00844935
- Where
- United States
- Sponsor
- University of California, San Francisco
Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control.
Effects of Inspiratory Muscle Training on Cardiovascular Function in Hypertension.
The purpose of this study is to determine inspiratory muscle training effects on blood pressure, functional capacity and quality of life in hypertensive patients.
- Conditions
- Reduction of Blood Pressure in Hypertensive Patients., Improvement of Cardiovascular Autonomic Control., Improvement of Functional Capacity., Improvement of Quality of Life.
- Trial name
- TREMVEN (NCT01250444)
- Testing
- Inspiratory Muscle Training
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Chronic Migraine, Headache
Comprehensive Approach to Lifestyle Modification in Chronic Migraine
Migraine is a highly prevalent neurological disorder and one of the leading causes of disability worldwide, substantially affecting quality of life and individuals during their most productive years.
- Trial name
- CALM-Migraine (NCT07802860)
- Testing
- Comprehensive Lifestyle Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Occupational Stress, Sleep Quality
Curcumin Nano Patch and Autonomic Function in Shift-Working Healthcare Professionals
This randomized, open-label, placebo-controlled crossover study compares a curcumin-containing patch with a cooling placebo patch without curcumin in healthcare professionals who work rotating shifts.
- Trial name
- NCT07910279
- Testing
- Curcumin Nano Patch
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital