Clinical trials: Helping Behavior
Heart Failure, Cardiac Failure
Clinical Trial to Evaluate the the ReliantHeart HeartAssist 5® VAD System in Patients Awaiting Heart Transplantation
The purpose of the study is to evaluate the safety and effectiveness of the ReliantHeart HeartAssist 5® VAD System in patients listed for heart transplantation and at risk of death from refractory end-stage heart failure.
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Heart Failure, Left-sided
- Trial name
- NCT02205411
- Testing
- HeartAssist 5® VAD System, Control VAD
- Where
- 14 sites in United States
- Volunteers
- 17 people
- Sponsor
- ReliantHeart Inc.
Ventricular Tachycardia, End-stage Heart Failure
Ventricular Tachycardia Ablation in LVAD Patients
The CHANNELED-Registry is a multicenter retrospective study to (1) systematically assess the mechanism and origin of ventricular tachycardia in patients with end-stage heart failure carrying an left ventricular assist device…
- Conditions
- Ventricular Tachycardia, End-stage Heart Failure, Ventricular Arrythmia, LVAD (Left Ventricular Assist Device)
- Trial name
- CHANNELED (NCT06063811)
- Testing
- Ablation
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Köln
Sterility, Female, Reproductive Technology, Assisted
Prothrombotic Biomarkers and Ovarian Stimulation
The aim of this study is to assess the impact of different protocols used for ovarian stimulation during in vitro fertilization procedures (IVF) on prothrombotic biomarkers (blood coagulation markers associated with…
- Trial name
- HEMOSTIM (NCT04188444)
- Testing
- Blood test
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people
- Sponsor
- University Hospital, Geneva
Healthy Person
Effect of Soft Robotic Exosuit Assistance in Healthy People
This study aims to find out what effect there is on the difference in energy use efficiency and gait analysis when walking while wearing knee and hip assist robots based on flexible power structures for normal people.
- Trial name
- NCT05693233
- Testing
- EXO On, EXO Off, EXO Removed treadmill (Uphill_incline 10°) walking and simultaneous evaluation
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Thrombosis, Blood Coagulation Disorder
Dynamics of Platelet Activation in Patients With Ventricular Assist Device (VAD)
Consenting patients with end-stage heart failure that are implanted with/candidates for implant of a short-term/durable mechanical circulatory support device (e.g.: percutaneous microaxial pumps (Impella), extracorporeal membrane…
- Conditions
- Thrombosis, Blood Coagulation Disorder, Platelet Thrombus, Platelet Dysfunction Due to Aspirin
- Trial name
- PASVAD (NCT03255928)
- Testing
- PAS assay, TGT
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Palliative Care, Kidney Failure, Chronic
A Communication Tool to Assist Older Adults Facing Dialysis Choices
The purpose of this study is to test the effect of the "Best Case/Worse Case" (BC/WC) communication tool on receipt of palliative care and intensity of treatment at the end of life, quality of life, and quality of communication…
- Conditions
- Palliative Care, Kidney Failure, Chronic, Decision Making, Decision Support Techniques
- Trial name
- NCT04466865
- Testing
- Best Case/Worst Case communication tool training
- Where
- 11 sites in United States
- Volunteers
- 407 people
- Sponsor
- University of Wisconsin, Madison
Heart Failure, Ventricular Assist Device
Influence of Telemonitoring on the Management of LVAD-patients
The current study aims to investigate whether telemedical monitoring in patients with terminal heart failure and an implanted left ventricular assist device (LVAD) has an influence on LVAD-associated complications…
- Conditions
- Heart Failure, Ventricular Assist Device, Telemedicine
- Trial name
- NCT04613401
- Testing
- questionnaire (observational study)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital, Essen
Respiratory Failure
Pressure Support Ventilation (PSV) Versus Neurally Adjusted Ventilator Assist (NAVA) During Acute Respiratory Failure (ARF)
Acute respiratory failure (ARF) is a life-threatening emergency which occurs due to impaired gas exchange. In the US, the number of hospitalisations owing to acute respiratory failure was 1,917,910 in the year 2009.(1) The…
- Trial name
- NCT03271671
- Testing
- NAVA during Non invasive ventilation, PSV during Non invasive ventilation
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Obstructive Sleep Apnea
Device-Assisted Oropharyngeal Rehabilitation in Obstructive Sleep Apnea Patients Using Continuous Positive Airway Pressure
The goal of this clinical trial is to evaluate the effectiveness of device-assisted oropharyngeal rehabilitation (OPR) in improving upper airway muscle function and reducing obstructive sleep apnea (OSA) severity in adult…
- Trial name
- NCT06999746
- Testing
- Control, Oropharyngeal Exercise, Continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Cheng-Kung University Hospital
Accidental Falls, Injuries
The Safety Integration Stakeholders (SAINTS) Program to Integrate Worker and Patient Safety in Oregon Rural Hospitals
The safety integration stakeholders (saints) program to integrate worker and patient safety in Oregon rural hospitals. The rationale is that the saints program will positively impact outcomes by identifying and training peer…
- Trial name
- SAINTS (NCT06302088)
- Testing
- SAINTS program
- Volunteers
- 240 people
- Sponsor
- Oregon Health and Science University
Essential Hypertension, Metabolic Cardiovascular Syndrome
Technological Innovation in the Virtual Assistance of Patients With Uncontrolled Arterial Hypertension - Hyper 2
The purpose of this study is to evaluate the effectiveness of the use of artificial intelligence in home monitoring in patients with uncontrolled arterial hypertension.
- Conditions
- Essential Hypertension, Metabolic Cardiovascular Syndrome, Heart Disease Risk Factors
- Trial name
- Hyper2 (NCT05843682)
- Testing
- Using the Avatr App
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Sao Paulo General Hospital
Multiple Sclerosis, Performance Enhancement
Effects of DHA in Patients With Multiple Sclerosis
This clinical trial will investigate the effects of combining therapeutic exercise with DHA supplementation in 100 patients with multiple sclerosis using a randomized controlled design.
- Conditions
- Multiple Sclerosis, Performance Enhancement, Supplemental Nutrition Assistance Program Education, Strength Outcomes
- Trial name
- DHAME (NCT07346703)
- Testing
- Docosahexaenoic Acid (DHA) Dietary Supplement, Sunflower Oil
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Transfemoral Amputation, Artificial Limbs
Assist-Knee: Energy-Harvesting Knee Prosthesis
The purpose of this research is to validate the Assist-Knee design and function by collecting pilot data during the stand-to-sit-to-stand transition in transfemoral prosthesis users when using the Assist-Knee to harvest energy…
- Trial name
- NCT04023045
- Testing
- Assist-Knee, Habitual Prosthesis
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Orthocare Innovations, LLC
Parkinson Disease, Deglutition Disorders
Describe to Better Understand, the Mealtime of People With Parkinson's Disease Dependent on Food Intake
The main objective is to describe strategies (verbal, non-verbal (gesture, intonation), and environmental), designed and used by the assisting/aided dyad to feed a dysphagic dependent person by articulating the safe and hedonic…
- Trial name
- AideAlimPark (NCT05898139)
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Toulouse
Osteoarthritis, Knee
Computer-Assisted Total Knee Replacement Kinematics: DePuy Sigma Posterior Cruciate Substituting Knee and the DePuy Sigma RP Rotating Platform Knee
Primary Research Questions: 1. Do patients with knee osteoarthritis (OA) who undergo total knee replacement with a Sigma rotating platform have better clinical outcomes at 2 years post surgery (i.e.
- Trial name
- NCT00375856
- Testing
- DePuy P.F.C.® Sigma Rotating Platform Knee
- Where
- 3 sites in Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Queen's University
Substance Use Disorders, HIV
ASK-PrEP (Assistance Services Knowledge-PrEP)
ASK-PrEP is a two-arm randomized controlled trial (RCT), with a Stepped Care approach, among HIV-negative trans women and men who have sex with men with a substance use disorder (SUD).
- Trial name
- NCT05934877
- Testing
- PrEP navigation + text messaging, Standard of Care, Contingency Management
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Friends Research Institute, Inc.
Aging
The Effect of Exercise With Wearable Walking Assist Robot in Various Environments
This single-blinded, randomized, controlled trial includes 60 healthy adults. The participants were randomized to four different groups.
- Trial name
- NCT04920201
- Testing
- Over-ground walking without GEMS-H, Over-ground walking with GEMS-H with resist mode, Stair ascent with GEMS-H with assist mode
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Hernia
Does Preop Midazolam Maintain Blood Glucose Norms in the Non Diabetic Perioperative Period
This research is being done to investigate if patients who receive a commonly used sedative drug, known as midazolam, are likely to have high blood sugar levels during the stressful period during and immediately after surgery.
- Trial name
- NCT01641653
- Testing
- Normal saline, Midazolam
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Hepatitis C, Chronic, Hepacivirus
Adherence in Patients Receiving PegIntron Pen/Rebetol for Hepatitis C in Conjunction With a Patient Assistance Program (Study P04281)(COMPLETED)
Patients receiving a patient assistance program during therapy for Hepatitis C will be enrolled into this study. All patients will receive PegIntron pen and Rebetol according to label and the patient assistance program.
- Trial name
- NCT00704522
- Testing
- Peginterferon alfa-2b (SCH 54031), Ribavirin (SCH 18908), Patient assistance program
- Volunteers
- 601 people
- Sponsor
- Merck Sharp & Dohme LLC
Breast Cancer Screening, Artificial Intelligence (AI)
A Trial Comparing Screening Mammography With and Without Assistance From Artificial Intelligence for Breast Cancer Detection and Recall Rates in Adult Patients
The goal of this clinical trial is to compare patient-centered outcomes when screening digital breast tomosynthesis (DBT) exams are interpreted with versus without a leading FDA-cleared artificial intelligence (AI)…
- Trial name
- NCT06934239
- Testing
- Artificial intelligence (AI) decision-support tool
- Where
- 6 sites in United States
- Volunteers
- 400,000 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
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