Clinical trials: Helping Behavior
Heart Failure
Massage Therapy for Self-efficacy in LVAD Recipients
This pilot study evaluates the role of massage therapy to improve self-efficacy in patients with advanced heart failure who have recently received a left-ventricular assist device.
- Trial name
- NCT04018508
- Testing
- Massage
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medstar Health Research Institute
Behavior, Health
Preventive Reminder Ordering AssistanCe Via Texting for Improved Visit Encounters
A substantial portion of the United States population remains overdue for key screenings, despite availability and insurance coverage of preventive health services.
- Trial name
- PROACTIVE (NCT07636187)
- Testing
- Pre-visit and post-visit patient messaging, Default pended order, EHR communication
- Where
- United States
- Volunteers
- 16,416 people
- Sponsor
- University of Pennsylvania
Right Heart Failure
Predictive Value of Vasodilator Challenge for Right Heart Failure After LVAD Implantation
Prospective evaluation of the predictive value for post-LVAD right ventricular failure (RHF) of pulmonary vasodilator challenge, in addition to current laboratory, echocardiographic and haemodynamic parameters.
- Trial name
- PREVV-RHF-LVAD (NCT05836233)
- Testing
- Pulmonary Vasodilators
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- San Camillo Hospital, Rome
Heart Failure
Self-Management App for Patients With Left-Ventricular Assist Devices
The purpose of this study is to evaluate the use of VAD Care App in an out-patient mechanical circulatory support program. The specific aim for this pilot study is to obtain preliminary efficacy data of the VAD Care App as a…
- Trial name
- NCT03049748
- Testing
- Mobile phone app (VAD Care App), Usual LVAD Care
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Aortic Valve Disease, Mitral Valve Disease
VIenna Pilot Study for Automated Annular Suturing Technology
The objective of this study is to compare surgical outcomes between patients who underwent valve replacement with and without the help of the automated annular suturing technology.
- Trial name
- VIP-RAM (NCT04659655)
- Testing
- automated annular suturing
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Instrumental Delivery, Medical Device
ASSIST Ethiopia: Feasibility Clinical Investigation of the Odonassist™ Medical Device
The Innovation The OdonAssist™ is a medical device for assisted vaginal delivery (AVD), that is defined by the need of additional procedure to facilitate childbirth in order to reduce foetal-maternal risks.
- Conditions
- Instrumental Delivery, Medical Device, Feasibility Study, Acceptability Study
- Trial name
- ASSISTEthiopia (NCT06918509)
- Testing
- OdonAssistTM
- Where
- Ethiopia
- Volunteers
- 20 people
- Sponsor
- Doctors with Africa - CUAMM
Infertility
Impact of Embryo Cryopreservation on Birth Weight
Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement. No study has compared the BW of siblings conceived using the same oocyte/embryo cohort.
- Trial name
- NCT03989843
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
Parenting, Psychosis
Understanding and Helping Families: Parents With Psychosis
The purpose of this trial is to explore parent-child interactions in parents with and without psychosis, and ascertain whether a brief (10 week) supported self-help parenting program offered to parents in their own homes can help…
- Conditions
- Parenting, Psychosis, Schizophrenia
- Trial name
- NCT02622048
- Testing
- Triple P Positive Parenting Programme
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Manual Pressure, Repositioning
Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance
The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower…
- Conditions
- Manual Pressure, Repositioning, Colonoscopy, Colon Polyp
- Trial name
- NCT06496958
- Testing
- CO2 insufflation with an abdominal compression device, Water exchange colonoscopy
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Stroke
Improving Balance and Energetics of Walking Using a Hip Exoskeleton
Robotic lower limb exoskeletons aim to improve or augment limb functions. Automatic modulation of robotic assistance is very important because it can increase the assistive outcomes and guarantee safety when using exoskeletons.
- Trial name
- NCT05447884
- Testing
- A zero impedance mode, controlling a wearable bilateral hip exoskeleton, A personalized optimal assistance mode, controlling a wearable bilateral hip exoskeleton, A free walking mode, without wearing a wearable bilateral hip exoskeleton
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Respiratory Failure
Comparative Effects of Variable Pressure Support, NAVA and PAV
Experimental animal data suggest that increasing breathing pattern variability in mechanical ventilation could be beneficial. Variable ventilation can be induced through the following modes: Neurally Adjust Ventilatory Assist…
- Trial name
- NCT02499276
- Testing
- PSV, NAVA, PAV, Variable-PSV
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Bronchiolitis
Non-Invasive Ventilation Versus Neurally-Adjusted Ventilatory Assistance (NAVA) for the Treatment of Bronchiolitis
This project aims to answer whether the use of a Neurally-Adjusted Ventilatory Assistance mode for non-invasive ventilation in pediatric patients with bronchiolitis results in improved comfort and reduced escalations in therapy…
- Trial name
- NCT06053684
- Testing
- Standard Non-Invasive Mechanical Servo Ventilation, Neurally-Adjusted Ventilatory Assistance (NAVA) Non-Invasive Mechanical Servo Ventilation
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Montefiore Medical Center
Men in Relation, Couple Whose Taken Care in Medical Assisted to Reproduction
Sexuality of the Man Whose Couple is Taken Care of in Medical Assistance to Procreation. Study of Case Witnesses
According to the World Health Organization and the World Association for Sexual Health, sexual health is directly associated with the psychological well-being and quality of life of each individual.
- Trial name
- AMPlaisir (NCT03459326)
- Testing
- IIEF (International Index of Erectile Function questionnaire )
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sepsis, Shock, Septic
Sepsis Assessment in Belgian Emergency Rooms
To validate the use of the Heparin Binding Protein (HBP) concentration to assist in the evaluation of patients admitting to the emergency department with suspected infection.
- Conditions
- Sepsis, Shock, Septic, Severe Sepsis
- Trial name
- SABER (NCT02424721)
- Where
- 4 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Axis Shield Diagnostics Ltd
Heart Failure
Investigation to Optimize Hemodynamic Management of Left Ventricular Assist Devices Using the CardioMEMS™
This observational post market study is intended to characterize hemodynamic-guided management of patients with an existing left ventricular assist device (LVAD) to protocol specified target ranges and its impact on functional…
- Trial name
- INTELLECT 2-HF (NCT03247829)
- Testing
- Hemodynamic management using CardioMEMS HF System
- Where
- 23 sites in United States
- Volunteers
- 101 people
- Sponsor
- Abbott Medical Devices
Chronic Heart Failure, Heart Transplant Recipient
Heart Failure Patient Management and Interventions Using Continuous Patient Monitoring Outside Hospitals and Real-world Data
The goal of this study is to create a digital platform for managing patients with chronic heart failure, those with long-term ventricular assistance, or heart transplant recipients.
- Conditions
- Chronic Heart Failure, Heart Transplant Recipient, Left Ventricular Assist Device
- Trial name
- RETENTION (NCT07008729)
- Testing
- Heart monitoring tools (data revision), Control (Standard treatment)
- Where
- 6 sites in Germany, Greece and 2 more
- Volunteers
- 390 people
- Sponsor
- Puerta de Hierro University Hospital
Heart Failure, Cardiomyopathy
The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation
The main purpose of this research is to determine whether injecting mesenchymal precursor cells (MPC) into the heart during surgery to implant a left ventricular assist device (LVAD) is safe.
- Conditions
- Heart Failure, Cardiomyopathy, Ventricular Dysfunction
- Trial name
- NCT01442129
- Testing
- MPC Intramyocardial injection, Control Solution
- Where
- 11 sites in United States
- Volunteers
- 30 people
- Sponsor
- Deborah Ascheim
Graves' Disease, Thyroid Disease
Shared Decision Making in Graves Disease - Graves Disease (GD) Choice
The investigators' decision aid for patients with GD, GD Choice, will be the result of a user-centered participatory action research involving) synthesis of the best available evidence from the literature and real-world registry…
- Conditions
- Graves' Disease, Thyroid Disease, Hyperthyroidism
- Trial name
- NCT02107794
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Mayo Clinic
Breath Training Styles
Neurological Evidence of Diverse Self-Help Breathing Trainings with Virtual Reality and Bio-Feedback Assistance
The goal of this research is to learn about the neuro-mechanism beneath breath training, mindfulness meditation, or periods of idleness.
- Trial name
- NCT06656741
- Testing
- Resting State, Mindful Breathing, Guided Breathing
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hei-Yin Hydra Ng
Brain (Nervous System) Cancers, Brain Tumor, Primary
3D Decision Support Tool for Brain Tumour Surgery Development and Validation: Observational Study
This observational study (STRATUM-OS) aims to collect the necessary data from a cohort of patients with planned surgery for suspected intra-axial malignant brain tumours (both primary and secondary) following the standard…
- Trial name
- STRATUM-OS (NCT07036783)
- Volunteers
- 320 people
- Sponsor
- Fundación Canaria Instituto de Investigación Sanitaria de Canarias
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