Clinical trials: Hemodialysis Access
Hemodialysis Access Failure
Three-dimensional (3D) Printed Hemodialysis Vascular Model
Infiltration of a surgically-placed hemodialysis vascular access (HVA) is recognized as a major contributor to the high hospital re-admission rate in dialysis-dependent patients.
- Trial name
- NCT05096416
- Testing
- The three-dimensional (3D) printed hemodialysis vascular model
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Patency, Infection
Prevention of Dialysis Catheter Malfunction With Prophylactic Use of a Taurolidine Containing Urokinase
The objective of our study is to investigate whether the substitution of the standard locking solution with a locking solution containing taurolidine and urokinase weekly (Taurolock ™ U 25,000 - www.taurolock.com ) reduces the…
- Trial name
- NCT02036255
- Testing
- Taurolidine Urokinase, Taurolidine Heparin
- Where
- 9 sites in Belgium
- Volunteers
- 68 people
- Sponsor
- Universitair Ziekenhuis Brussel
Hemodialysis Patient, Hemodialysis Catheter
The Effect of Arteriovenous Fistula Care Training Given to Hemodialysis Patients on Quality of Life, Comfort and Self-Care Behaviours
This study will be conducted to evaluate the effect of Arterio-Venous Fistula (AVF) care training given to hamodialysis patients on quality of life, comfort and self-care behaviours.
- Trial name
- Fistula care (NCT06959914)
- Testing
- Training group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kafkas University
End Stage Renal Disease (ESRD), Vascular Access Complication
Autologous Adipose Derived Mesenchymal Stem Cells (AMSC) in Reducing Hemodialysis Arteriovenous Fistula Failure
The aim of this phase 1 study is to determine the role of autologous adipose derived mesenchymal stem cells in the reduction of hemodialysis arteriovenous fistula failure when applied during the time of surgical creation.
- Trial name
- NCT02808208
- Testing
- Single Application of Adipose Derived Mesenchymal Stem Cells (AMSC), Two Applications of Adipose Derived Mesenchymal Stem Cells (AMSC)
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Mayo Clinic
Chronic Kidney Diseases, Pain, Procedural
Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients
For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety.
- Conditions
- Chronic Kidney Diseases, Pain, Procedural, Arteriovenous Fistula
- Trial name
- NCT07700680
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
End Stage Renal Failure on Dialysis
Vienna Vascular Access Studied on Exchange of Dialysis Catheters for Shunts Where Feasible
We will conduct a cross-section analysis regarding patients with catheter-based vascular Access (VA) in Vienna. Collected data will include demographic and clinical information such as age, gender, co-morbidities and imaging data…
- Trial name
- ViennaACTSNOW (NCT05704140)
- Testing
- Catheter based Dialysis
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Wilhelminenspital Vienna
End Stage Renal Disease
Xeltis Hemodialysis Access (aXess) Conduit: aXess-E Study
A prospective, single arm, non-randomized feasibility study to confirm the safety and performance of the Xeltis Hemodialysis Access conduit, aXess-E, in subjects older than 18 years with end-stage renal disease, who plan to…
- Trial name
- NCT06329310
- Testing
- aXess-E conduit
- Where
- 2 sites in Portugal, Serbia
- Volunteers
- 20 people
- Sponsor
- Xeltis
Dysfunction of Hemodialysis Vascular Access (Fistula and Graft)
Drug-Eluting Balloon Angioplasty for the Treatment of Hemodialysis Vascular Access Stenosis (DEBAVAS)
Paclitaxel is an antiproliferative drug that can limit vascular intimal hyperplasia. Paclitaxel-coated balloons already have indications in the treatment of peripheral arterial disease.
- Trial name
- B3AV (NCT02408822)
- Testing
- PTA Balloon dilatation catheter Advance® (Cook® Medical), Drug-eluting PTA Balloon dilatation catheter Advance® 18 PTX®
- Where
- 3 sites in France
- Volunteers
- 52 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Arteriovenous Fistula Renal Dialysis Devices Obstruction
Primary Patency in Post-angioplasty Dysfunctional Arteriovenous Fistula in Renal Dialysis: Paclitaxel-releasing PTA Balloon Catheter vs PTA Balloon
In recent years the use of paclitaxel releasing percutaneous transluminal angioplastic (PTA) balloon catheter is spreading in vascular pathology, mainly in stenosis infrainguinal arteries.
- Trial name
- FISBAL (NCT02565953)
- Testing
- Paclitaxel-releasing PTA balloon catheter, PTA balloon catheter
- Where
- 4 sites in Spain
- Volunteers
- 134 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Arteriovenous Fistula Stenosis, Arteriovenous Fistula
A Prospective, Multi-center Study to Evaluate Efficacy and Safety of BSJ020R in Treatment of AVF for Hemodialysis (RANGER AV Japan Study)
A prospective, multi-center study to evaluate efficacy and safety of BSJ020R in treatment of AVF for hemodialysis
- Conditions
- Arteriovenous Fistula Stenosis, Arteriovenous Fistula, Vascular Access
- Trial name
- NCT06639451
- Testing
- RANGER™ Paclitaxel Coated Balloon Catheter
- Where
- 8 sites in Japan
- Volunteers
- 186 people
- Sponsor
- Boston Scientific Corporation
End-Stage Renal Disease
Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,
- Trial name
- NCT05880537
- Testing
- Nexeon Arterial Venous Allograft
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- LifeNet Health
Hemodyalysis
AVF-MONITOR POC Proof-of-concept Study
This is a proof-of-concept single-centre prospective longitudinal interventional study performed in AVF patients under HD treatment at the Nephrology and Dialysis Department of the ASST-Papa Giovanni XXIII (Bergamo, Italy)…
- Trial name
- AVFMONITOR POC (NCT07318025)
- Testing
- AVF MONITOR
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
The Aim of This Study is to Follow up Short Term "3-6 Months"& Mid Term" 6-12months "Outcomes of Vascular Access" Native and Synthetic "in ESRD Pediatrics
Primary Patency in Pediatric Patients With Hemodialysis Access
Vascular access in the pediatric hemodialysis patients is a challenging,but necessary. It requires proper advance planning to assure that the best permanent access is placeds long life span.
- Trial name
- NCT06034717
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alaa Gameil Abd El-salam Hussien
Kidney Diseases, ESRD
Safety and Efficacy of Angiotech Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
This is a multi-center clinical study in subjects requiring arteriovenous grafts in the upper extremity for hemodialysis access. All subjects will provide informed consent before undergoing any study procedures.
- Trial name
- NCT00448708
- Testing
- Vascular Wrap Paclitaxel-Eluting Mesh, Lifespan® ePTFE Vascular Graft
- Where
- 33 sites in United States
- Volunteers
- 222 people
- Sponsor
- Angiotech Pharmaceuticals
Hemodialysis Access Failure
Immediate-access Arteriovenous Versus Standard Arteriovenous Grafts in Hemodialysis Patients
Arteriovenous fistulae (AVF) are considered the main access for hemodialysis (HD). Arteriovenous grafts (AVGs) are an alternative access modality in patients with exhausted native venous access.
- Trial name
- NCT04388397
- Testing
- Arteriovenous Grafts
- Where
- 2 sites in Egypt
- Volunteers
- 477 people
- Sponsor
- Egyptian Biomedical Research Network
Thrombosis
Improving Arteriovenous Fistula Patency
All vascular access guidelines recommend monitoring and surveillance protocols to prevent vascular access complications in hemodialysis units.
- Trial name
- METTRO (NCT02111655)
- Testing
- Second generation surveillance of AVF, vital signs, physical examination of AVF
- Where
- 5 sites in Spain
- Volunteers
- 212 people
- Sponsor
- Hospital Infanta Sofia
Kidney Failure
Aggrenox Prevention of Access Stenosis
The objective of the study is to determine whether Aggrenox (Boehringer-Ingelheim) prolongs primary unassisted patency in newly created arteriovenous grafts.
- Trial name
- GRAFT (NCT00067119)
- Testing
- Aggrenox
- Where
- 9 sites in United States
- Volunteers
- 649 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
End Stage Renal Disease, Vascular Access Complication
Bicarbonate vs Heparin Catheter Lock in Chronic Hemodialysis Patients
Prospective clinical trial to evaluate the efficacy of catheter lock with bicarbonate vs heparin in chronic hemodialysis patients.
- Conditions
- End Stage Renal Disease, Vascular Access Complication, Catheter Complications, Hemodialysis Access Failure
- Trial name
- BICATH (NCT04054128)
- Testing
- Sodium Bicarbonate 7.5% Injection, Heparin Sodium, 1000 Units/mL Injectable Solution 1
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital General "Dr. Miguel Silva" de Morelia
Hemodialysis, Difficult Vascular Access Cannulation
Pre-Cannulation Ultrasound Vascular Mapping Combined With Handgrip Exercise and Local Cryotherapy in Hemodialysis Patients With Difficult Cannulation
This pilot randomized controlled trial evaluated a multicomponent intervention for adult maintenance hemodialysis patients with difficult vascular access cannulation.
- Trial name
- NCT07842939
- Testing
- Pre-Cannulation Ultrasound Vascular Mapping, Handgrip Exercise, Local Cryotherapy
- Where
- Taiwan
- Volunteers
- 69 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Kidney Diseases, Dialysis; Complications
AVF Awareness Among Advanced CKD Patients
This cross-sectional study aims to assess awareness regarding arteriovenous fistula creation among patients with advanced chronic kidney disease, including pre-dialysis patients and those receiving maintenance hemodialysis, at…
- Conditions
- Chronic Kidney Diseases, Dialysis; Complications, Arteriovenous Fistula, Kidney Failure, Chronic
- Trial name
- NCT07817953
- Volunteers
- 116 people
- Sponsor
- Assiut University