Clinical trials: Hemodialysis-Induced Symptom
Intradialytic Hypotension, Hemodialysis-Induced Symptoms
Timing of Intradialytic Exercise and Its Impact on Intradialytic Hypotension
The objective of this study is to compare the rate of low blood pressure events (Intradialytic Hypotension: IDH) when intradialytic exercise is performed in the first half of the hemodialysis (HD) session as compared to that when…
- Trial name
- NCT03504943
- Testing
- Early Intradialytic Exercise, Late Intradialytic Exercise
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- University of Manitoba
ESRD, Fatigue
The Effect of Blood Flow Rate on Dialysis Recovery Time in Patients Undergoing Maintenance Hemodialysis
A majority of patients with end-stage renal disease (ESRD) on in-center hemodialysis (HD) require several hours to recover from fatigue after an HD session.
- Conditions
- ESRD, Fatigue, Hemodialysis-Induced Symptom
- Trial name
- NCT03943212
- Testing
- Blood Flow Rate Reduction, Control
- Where
- 18 sites in United States
- Volunteers
- 102 people
- Sponsor
- Satellite Healthcare
Anemia, End Stage Renal Disease
16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis
The purpose of this study is to evaluate the hemoglobin response (efficacy), safety, and tolerability of orally administered AKB-6548 in participants with end stage renal disease undergoing chronic hemodialysis.
- Trial name
- NCT02260193
- Testing
- AKB-6548
- Where
- 16 sites in United States
- Volunteers
- 94 people
- Sponsor
- Akebia Therapeutics
Hemodialysis-Induced Symptom
Factors Influencing Hemoglobin Variability and Its Association With Mortality in Hemodialysis Patients
The aim of the study is to investigate the factors influencing hemoglobin variability with inflammatory and nutritional parameters and its associations with all-cause mortality among hemodialysis patients.
- Trial name
- NCT03454906
- Volunteers
- 169 people
- Sponsor
- Baskent University
Anemia, Malnutrition
Environmental Exposure to Lead and Its Health Effects on Patients With Maintenance Hemodialysis
One thousand patients with LHD who have no history of exposure to lead will be observed for 18 months. Blood lead level(BLL), biochemical data, hemoglobin, albumin, Cr, high sensitivity C-reactive protein (HsCRP), and blood cell…
- Conditions
- Anemia, Malnutrition, Inflammation, Lead Poisoning
- Trial name
- NCT00926406
- Testing
- lead chelation therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital
Arteriovenous Fistula, Vascular Diseases
Hand Acceleration Time (HAT) Assessment Before and After Creating an Arteriovenous Fistula (AVF)
The main objectives of this observational study are to compare the results of the sonographic parameter hand acceleration time (HAT) measured before and after creating an arteriovenous fistula (AVF) for hemodialysis and assess if…
- Trial name
- HATs-ACCVAS (NCT06187207)
- Testing
- Hand acceleration time (HAT) measurement
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Universitari de Bellvitge
Hemodialysis Complication, Hemodialysis-Induced Symptom
Evaluation of Curcumin's Effect on Inflammation in Hemodialysis Patients
Programmed ingestion of turmeric has no adverse effects and reduces plasma level of hs-CRP, IL-6 and TNF-α accompanying with increases albumin levels in hemodialysis patients.
- Trial name
- NCT03144882
- Testing
- Curcumin Pill
- Volunteers
- 71 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
End-stage Renal Disease (ESRD), Kidney Disease
Sympathetic Activity in Patients With End-stage Renal Disease on Peritoneal Dialysis
Hypothesis: Patients starting peritoneal dialysis with a glucose-based regimen have high sympathetic activity in response to an increase in leptin and insulin.
- Trial name
- SAPD (NCT01228279)
- Testing
- DIANEAL, EXTRANEAL
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
Chronic Kidney Disease (CKD), Hyperkalemia
Chronic Kidney Disease, Hyperkalemia and Echocardiographic Changes
Patients with CKD ( eGFR \< \<60 mL/min/1,73 m2) presenting to emergency department with isolated hyperkalemia will be study population. Pre and post treatment ECG and echocardiographic findings will be recorded.
- Conditions
- Chronic Kidney Disease (CKD), Hyperkalemia, Hemodialysis
- Trial name
- NCT06635590
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
Opiate Addiction
Opiate Detoxification Using the Combined Hemoperfusion-hemodialysis
The purpose of this study is to determine whether combined hemoperfusion-hemodialysis treatment is an alternative drug-free, effective, and safe treatment for opiate detoxification.
- Trial name
- HPDMT (NCT01021566)
- Testing
- Combined hemoperfusion-hemodialysis, Methadone
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First People's Hospital of Foshan
Efficacy, Team, Adverse Reaction to Drug
Efficacy and Safety of Sertraline in the Treatment of Maintenance Hemodialysis Patients With Depression
Depression is a common mental disorder in patients undergoing maintenance hemodialysis (MHD), which increases the risk of cardiovascular events, hospitalization rates, and mortality, but has not received enough attention from…
- Trial name
- NCT06124417
- Testing
- Sertraline
- Where
- China
- Volunteers
- 125 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Dyspnea; Uremic, End Stage Renal Disease
Dyspnea Assessment in Hemodialysis Patients
Shortness of breath is very common among patients on dialysis for kidney failure; however, its causes are often not understood. This study will explore the lungs and the heart of these patients to determine the causes of…
- Conditions
- Dyspnea; Uremic, End Stage Renal Disease, Chronic Lung Disease, Chronic Heart Disease
- Trial name
- NCT03773991
- Testing
- Lung MRI, Sodium MRI, Chest CT
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
End Stage Renal Failure on Dialysis, Body Fluid Retention
Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- End Stage Renal Failure on Dialysis, Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- CI/HD (NCT02485782)
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, BCM- Body Composition Monitor, Fresenius Medical Care, SCHILLER, BR-102 plus, Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 48 people
- Sponsor
- Medical University of Warsaw
Chronic Kidney Disease
Reducing Hemodialysis Induced Recurrent Brain Injury to Improve Patients' Lives
Patients who receive dialysis for kidney failure suffer severe cognitive impairment. Hemodialysis causes circulatory stress and ischemia, which causes severe brain injury.
- Trial name
- NCT03342183
- Testing
- Intervention Arm, Control Arm
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Renal Failure Chronic Requiring Hemodialysis, Haemodialysis-induced Symptom
Mechanisms of Intradialytic Hypertension
Patients with end-stage renal disease (ESRD) are at significantly higher risk for death due to cardiovascular disease. Those with paradoxical increases in blood pressure (BP) during hemodialysis (HD), defined as intradialytic…
- Conditions
- Renal Failure Chronic Requiring Hemodialysis, Haemodialysis-induced Symptom, Hypertension
- Trial name
- MID-H (NCT01947673)
- Testing
- Mindfulness Meditation, Health Education
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Haemodialysis-induced Symptom
Cerebral Blood Flow During Hemodialysis
The purpose of this study is to evaluate the effect of the hemodialysis procedure on cerebral blood flow (CBF) in elderly maintenance hemodialysis (HD) patients.
- Trial name
- NCT02272985
- Testing
- [15O]H2O PET-CT scan, NIRS (Invos)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
End Stage Renal Disease, Hemodialysis-Induced Symptom
Virtual Reality During Hemodialysis
The main objective of this investigation is to assess if an intradialysis virtual reality exercise-based program results in an improvement in physical function and if it results in high adherence rates to exercise.
- Trial name
- VRHD (NCT03456414)
- Testing
- Virtual reality exercise during hemodialysis
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Cardenal Herrera University
Hemodialysis Complication, Hemodialysis-Induced Symptom
Relationship Between Hemodynamic Change and Fluid Removed During Hemodialysis
Relationship between hemodynamic change and fluid removed during hemodialysis measured by non-invasive monitor
- Trial name
- NCT03901794
- Testing
- Non-invasive hemodynamic monitor
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea, Overhydration
Effect of Intermittent Hemodialysis on Sleep Apnea Syndrome in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of decreasing fluid overload by hemodialysis on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease on intermittent hemodialysis.
- Conditions
- Obstructive Sleep Apnea, Overhydration, End Stage Renal Disease
- Trial name
- SASinHD (NCT01860209)
- Testing
- Hemodialysis
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Sarcopenia, Anemia Associated With Chronic Kidney Disease (CKD)
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients
Sarcopenia, abbreviated as muscle loss, is a prevalent complication among patients with chronic kidney disease (CKD), particularly those with end - stage renal disease (ESRD). It significantly impacts patients' quality of life.
- Conditions
- Sarcopenia, Anemia Associated With Chronic Kidney Disease (CKD), Dialysis Patients
- Trial name
- HIF-PHI (NCT07162090)
- Testing
- Roxadustat, Recombinant human erythropoietin (EPO)
- Volunteers
- 60 people
- Sponsor
- Tianjin Medical University General Hospital