Clinical trials: Hernia, Incisional
Ventral Hernia
A Prospective, Observational Study Utilizing Phasix™ Mesh During Ventral and Incisional Hernia Repair Surgery
The objective of this study is to collect efficacy, safety and utility data with Phasix™ Mesh in ventral and incisional repair procedures by evaluating the following: 1.
- Trial name
- NCT01863030
- Testing
- Phasix mesh implant
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- John Roth
Incisional Hernia
Impact Evaluation of Incisional Hernia on Muscular and Postural Function
Purpose of study is to assess perioperative functional parameters of the anterior abdominal wall muscles and postural control status in patients with large and giant incisional hernias in a controlled diagnostic study.
- Trial name
- IHMPF-1 (NCT05990647)
- Testing
- Dynamometric tension assessment, Postural balance, Assessment of the hernia defect size
- Where
- Uzbekistan
- Volunteers
- 95 people
- Sponsor
- Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov
Hernia Incisional
The Mesh-RTL Project, for Prevention of Incisional Hernia
Introduction: By definition, the laparotomy is a surgical incision into the abdomen cavity performed to examine the abdominal and retroperitoneal organs.
- Trial name
- RTL (NCT04134455)
- Testing
- Mesh reinforcement, RTL reinforcement
- Where
- Mexico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Ventral and Ventral Insicional Hernia
LVHR Multicenter Study
The study aims to prove differences or equalities in outcome for patients operated with laparoscopic ventral hernia repair with different methods of fixation of mesh and with or without approximation of defect prior to…
- Trial name
- NCT00455299
- Testing
- Laparoscopic ventral hernia repair
- Where
- 2 sites in Norway
- Volunteers
- 156 people
- Sponsor
- Oslo University Hospital
Hernia, Ventral
Incisional Hernia Progression Over Time
This is a prospective multicenter study of patients diagnosed with a medium to giant incisional hernia (transverse defect >7 cm). Patients referred to the surgical outpatient clinic are invited to participate in the study.
- Trial name
- INPRO (NCT02616718)
- Testing
- Repeated computed tomography scan of abdomen
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Bispebjerg Hospital
Incisional Hernia
Does the Use of Prophylactic Mesh Reduce Incisional Hernia?
Incisional hernia is a common condition after abdominal surgery. Because linea alba has less vascularity, incisional hernia more common in midline incisions. It is seen in the general population between 11-20%.
- Trial name
- NCT04700956
- Testing
- primary abdominal closure, abdominal closure with prophylactic mesh
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Konya City Hospital
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Effect of Irrigation Pressure on Postoperative Complications and Surgical Field Clarity in Unilateral Biportal Endoscopic Surgery
This study is being done to find out if the height of the fluid bag and the direction of the surgical cut affect the pressure of the fluid used during unilateral biportal endoscopic (UBE) spine surgery.
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Degenerative Disease
- Trial name
- NCT07837427
- Testing
- Unilateral Biportal Endoscopic Surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fan Zhang
Umbilical Hernia Repair, Epigastric Hernia Repair
Outpatient Department Repair of Small Primary Ventral Hernias
Ventral hernias are among the most common conditions requiring surgical intervention. Due to their benign nature, elective repairs of primary ventral hernias are usually given low priority for planned surgery.
- Conditions
- Umbilical Hernia Repair, Epigastric Hernia Repair, Primary Ventral and Incisional Hernia Repair
- Trial name
- OPD-R (NCT07351760)
- Testing
- Outpatient department repair
- Where
- Sweden
- Volunteers
- 37 people
- Sponsor
- Karolinska Institutet
Incisional Hernia of Anterior Abdominal Wall
Study on the Efficacy of Prophylactic on Lay Mesh in Preventing Post-operative Hernia in Liver Transplant Patients
Study Design: Single-blinded, randomized, prospective clinical trial. Study Population: End-stage liver disease patients' candidates for liver transplantation.
- Trial name
- NCT04512469
- Testing
- Low molecular weight mesh
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Incisional Hernia, Parastomal Hernia
Ventral Hernia Improvement of Treatment and Life
The goal of this clinical trial called the VITAL study is to learn if surgery has a positive impact on the quality of life in patients with incisional or parastomal hernia.
- Conditions
- Incisional Hernia, Parastomal Hernia, Ventral Hernia
- Trial name
- VITAL (NCT06864377)
- Testing
- Quality of life questionnair
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Line Marker
Wound Infection, Incisional Hernia
PDS*Plus and Wound Infections After Laparotomy
The aim of this study is to ascertain if the use of PDS plus® reduces the number of wound infections and incisional hernia after midline and transverse laparotomy comparing to polyglactin suture.
- Trial name
- PDS*plus (NCT00998907)
- Testing
- PDS plus, PDS II
- Where
- Germany
- Volunteers
- 1,042 people
- Sponsor
- University Hospital, Saarland
Open Abdomen, Fascial Closure
Vacuum Assisted Wound Closure (VAWC) and Mesh Mediated Fascial Traction
The purpose of this multicenter trial is to prospectively evaluate a novel combination of vacuum assisted wound closure (VAWC) and mesh mediated fascial traction for closure of open abdomens.
- Trial name
- NCT00494793
- Testing
- VAWC and mesh mediated fascial traction
- Where
- 5 sites in Sweden
- Volunteers
- 111 people
- Sponsor
- Skane University Hospital
Abdominal Aortic Aneurysm, Morbid Obesity
Pilot Study on the Effectiveness and Safety of OPTILENE® SILVER MESH ELASTIC in Prevention of Surgical Site Infection (SSI) and Incisional Hernia (IH)
The aim of the study is to describe the effectiveness of Optilene® Silver Mesh Elastic on prevention of surgical site infection (SSI) at 6 months follow-up in patients undergoing urgent laparotomy by collecting clinical data on…
- Trial name
- SSIHLVER (NCT06547138)
- Testing
- Prophylactic mesh
- Where
- 5 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Aesculap AG
Incisional Hernia, Abdominal Wall Defect
Stepwise for the Treatment of Lateral Incisional Hernias
The best approach for lateral incisional hernia is not known. Posterior component separation (reverse TAR) offers the possibility of using the retromuscular space for medial extension of the challenging preperitoneal plane.
- Conditions
- Incisional Hernia, Abdominal Wall Defect, Abdominal Wall Hernia, Hernia
- Trial name
- NCT05205213
- Testing
- Surgical Technique (lateral retromuscular preperitoneal)
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Henares University Hospital
Ventral Incisional Hernia
Ultrasound Assessment of Ventral Hernia Defects
Quantitative radiographic imaging holds promise as a novel and innovative strategy to assess ventral hernia patients. Assessing abdominal wall changes surrounding ventral hernia using shear wave velocity values measured with…
- Trial name
- NCT03043079
- Testing
- Ultrasound Acoustic Radiation Forced Impulse Shear Wave Velocity
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Incisional Hernia Repair, Ventral Hernia Repair
Comparative Evaluation of Preoperative Preparation Methods in Patients With Large Incisional Hernias
Patients with large, complex, or giant incisional hernias often require advanced preoperative optimization to facilitate safe abdominal wall reconstruction and reduce postoperative complications.
- Trial name
- AWR-PREP (NCT07549113)
- Testing
- Botulinum Toxin A (Botox ), Progressive Preoperative Pneumoperitoneum, Combined Preoperative Preparation
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital
Incisional Hernia of Anterior Abdominal Wall, Dehiscence Wound
Prevention of Incisional Hernia With Mesh-suture at Umbilical Trocar Site.
Incisional hernia related to the umbilical trocar site is probably the most frequent complication after laparoscopic surgical procedures.
- Conditions
- Incisional Hernia of Anterior Abdominal Wall, Dehiscence Wound, Wound Infection
- Trial name
- INDURATE (NCT06251583)
- Testing
- duramesh suture
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Miguel A ngel Garci-a Urena
Neoplasms Malignant, Rectal Cancer
Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection
The goal of this clinical trial is to compare the efficacy of using polypropylene mesh for hernia prevention after stoma closure in patients with colorectal cancer and non-mesh repair.
- Conditions
- Neoplasms Malignant, Rectal Cancer, Hernia Incisional, Surgery
- Trial name
- ProMeLAR (NCT05939687)
- Testing
- mesh, non-mesh
- Where
- Russia
- Volunteers
- 142 people
- Sponsor
- Blokhin's Russian Cancer Research Center
Incisional Hernia
Long-term Follow-up of Incisional Hernia Repaired With Intraperitoneal Mesh
The intraperitoneal repair has been proven safe for the repair of incisional hernia and is accepted, together with the subfascial or retromuscular repair as the "gold-standard" for the repair of incisional hernia.
- Trial name
- NCT00891254
- Testing
- Implant of a prosthetic mesh
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Cirujanos la Serena
Incisional Ventral Hernia, Recurrent Ventral Hernia
Modified "Open Intraperitoneal Mesh" Technique of Incisional Ventral Hernia Repair
Ventral hernias, primary and recurrent, are major surgical challenge. We aim to investigate efficacy of modified technique of ventral hernias repair: an "open intraperitoneal mesh" technique.
- Trial name
- NCT01953302
- Testing
- modified "open mesh technique"
- Where
- Croatia
- Volunteers
- 124 people
- Sponsor
- Varazdin General Hospital