Clinical trials: Hernia, Inguinal
Hernia, Inguinal, Flat Foot
The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population
Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial to evaluate the efficacy and safety of local anesthetic Chloroprocaine at two different concentrations ( at 1% and 2%) in a pediatric…
- Trial name
- NCT03918798
- Testing
- Chloroprocaine 1% Injectable Solution, Chloroprocaine 2% Injectable Solution
- Where
- 9 sites in Italy, Spain
- Volunteers
- 164 people
- Sponsor
- Sintetica SA
Inguinal Hernia Repair, Postoperative Pain
Visually Guided TAP Block in Laparoscopic TAPP Hernia Repair
This prospective, randomized clinical study aims to evaluate the effectiveness of the Transversus Abdominis Plane (TAP) block performed under direct laparoscopic vision in reducing postoperative pain and improving recovery after…
- Conditions
- Inguinal Hernia Repair, Postoperative Pain, TAP Block
- Trial name
- VIS-TAP-TAPP (NCT07264699)
- Testing
- Laparoscopic Transversus Abdominis Plane (TAP) Block with Bupivacaine
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Hernia, Inguinal, Inguinal Hernia
Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia Surgery
The goal of this observational study is to learn how the length of pneumoperitoneum during laparoscopic inguinal hernia surgery may affect changes in blood bicarbonate levels.
- Trial name
- TAPPHCO3 (NCT07473583)
- Testing
- Laparoscopic Inguinal Hernia Repair (TAPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Haseki Training and Research Hospital
Cholecystitis, Liver Neoplasms
Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room
This study aims to evaluate the feasibility and accuracy of a non-contact, camera-based physiological monitoring technology in a perioperative setting (including anesthesia induction, surgery, and recovery).Conventional vital…
- Conditions
- Cholecystitis, Liver Neoplasms, Cholelithiasis, Inguinal Hernia
- Trial name
- IBPM (NCT07473687)
- Testing
- Non-contact rPPG software
- Where
- Taiwan
- Volunteers
- 315 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Postoperative Pain, Inguinal Hernia
No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair
The investigators hypothesize that not prescribing opioids after uncomplicated, outpatient IHR will be non-inferior to prescribing opioids (5 tablets of Oxycodone, 5mg; or surgeon preference for intolerance) with respect to…
- Trial name
- NCT05929937
- Testing
- Opioids, No opioids
- Where
- 8 sites in United States, Canada
- Volunteers
- 904 people
- Sponsor
- Clayton Petro
Patent Processus Vaginalis, Inguinal Hernia
Natural History of Infants With Patent Processus Vaginalis
This will be a multi-center prospective observational study of all patients who undergo laparoscopic pyloromyotomy. Subjects who have PPV will be followed up to just before their 18th birthday through annual phone calls or emails…
- Trial name
- HxPPV (NCT03042858)
- Testing
- Infants with PPV, Infants without PPV
- Where
- United States
- Volunteers
- 801 people
- Sponsor
- Children's Mercy Hospital Kansas City
Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery
Preemptive IV Ibuprofen for Neurocognitive Recovery and Analgesic Needs After Inguinal Hernia Surgery
The primary objective of this study is to evaluate the effects of preemptive intravenous ibuprofen administration on delayed neurocognitive recovery (dNCR), postoperative pain management, and the overall quality of recovery in…
- Conditions
- Inguinal Hernia Unilateral, Delayed Neurocognitive Recovery, Postoperative Pain, Neuroinflammation
- Trial name
- IBU-COG (NCT07424001)
- Testing
- Ibuprofen (400 mg x 4)
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mehmet Çiğdem
Postoperative Pain
Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)
This is a Phase 3, randomized, double-blind, saline placebo- and active-controlled, multicenter study to evaluate the analgesic efficacy and safety of HTX 011 administered via local administration into the surgical site in…
- Trial name
- NCT03237481
- Testing
- HTX-011, Bupivacaine HCl, Luer-lock applicator
- Where
- 24 sites in United States, Belgium
- Volunteers
- 418 people
- Sponsor
- Heron Therapeutics
Postoperative Pain
Phase 2 Herniorrhaphy Study for Opioid Elimination
This is a Phase 2, open-label study in subjects undergoing unilateral open inguinal herniorrhaphy.
- Trial name
- NCT03695367
- Testing
- HTX-011, Luer lock applicator, Vial access device
- Where
- 5 sites in United States
- Volunteers
- 63 people
- Sponsor
- Heron Therapeutics
Inguinal Hernia
PRO-RSTAP: Effect of TAP and RS Blocks on Recovery After Inguinal Hernia Surgery (PRO-RSTAP)
Inguinal hernia repair is a common surgical procedure, often performed as day-case surgery. Despite standardized surgical techniques, postoperative pain may delay recovery and occasionally lead to unplanned hospital admission.
- Trial name
- PRO-RSTAP (NCT07423910)
- Testing
- Transversus abdominis plane block (TAP block), Rectus sheath block (active), Ropivacaine
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Urinary Retention, Inguinal Hernia
Study to Prevent Postoperative Urinary Retention
Post-operative urinary retention (POUR) is a common complication after inguinal hernia repair with a reported incidence up 34%. It can be described as the inability to initiate urination or properly empty one's bladder following…
- Trial name
- STOP-POUR (NCT04491526)
- Testing
- TAMSULOSIN Mepha Ret Depocaps 0.4 mg, Control Intervention
- Where
- Switzerland
- Volunteers
- 312 people
- Sponsor
- Antonio Nocito, MD
Inguinal Hernia
Treatment of Occult Inguinal Hernias
Inguinal hernias are a common surgical problem. Best management of occult inguinal hernias, defined as hernias unable to be felt on physical exam, is unknown.
- Trial name
- NCT04815707
- Testing
- Occcult hernia repair
- Where
- 2 sites in United States
- Volunteers
- 252 people
- Sponsor
- The University of Texas Health Science Center, Houston
Inguinal Hernia Unilateral, Postoperative Wound Inflammation
Postoperative Ozonated Oil Dressing After Open Inguinal Hernia Repair: A Randomized Pilot Trial
This study looks at whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery.
- Trial name
- OZONE-HERNIA (NCT07328698)
- Testing
- ozonated oil, Standard Sterile Dressing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Nigde Omer Halisdemir University
Inguinal Hernia
Mesh Fixation Methods in Laparoscopic Hernia Repair: Glue vs. Sutures vs. Tacks
This study is a clinical trial that aims to compare three different methods for securing a surgical mesh during a specific type of groin (inguinal) hernia repair surgery.
- Trial name
- RCT (NCT07401082)
- Testing
- Cyanoacrylate Surgical Adhesive Fixation, Suture Mesh Fixation, Helical Titanium Tack Fixation
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Mesh, Inguinal Hernia
Mesh Design for Open Inguinal Hernia
Inguinal hernia repair is the most common operation performed by general surgeons worldwide, surgical repair is the only established definitive treatment for inguinal hernia with multiple variable described approaches, Since…
- Trial name
- NCT07386067
- Testing
- new mesh design for inguinal hernia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Children, Hernia, Inguinal
Comparing Inhalation and Total Intravenous Anesthesia Methods
This study compares the effects of anesthesia using target-controlled infusion (TCI) and inhalation methods on pediatric patients undergoing inguinal hernia repair.
- Trial name
- TIVA-IHA (NCT06467279)
- Testing
- Target Controlled İnfusion, Inhalation anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Inguinal Hernia Repair
Modified vs. Conventional Laparoscopic TAPP for Inguinal Hernia
This study aims to compare the outcomes of two laparoscopic techniques for repairing inguinal hernias: the modified tumescent technique (MT-TAPP) and the conventional laparoscopic transabdominal preperitoneal technique (CL-TAPP).
- Trial name
- NCT07373314
- Testing
- Modified Tumescent Laparoscopic TAPP (MT-TAPP) for the first group., Conventional Laparoscopic TAPP (CL-TAPP)
- Volunteers
- 60 people
- Sponsor
- University of Health Sciences Lahore
Postoperative Pain, Inguinal Hernia
Comparison of Local Anesthetic Infiltration and Different Fascial Plane Blocks in Inguinal Hernia Repair
In this study, quadratus lumborum block (QLB), transversus abdominis plane (TAP) block, and local anesthetic infiltration will be performed preoperatively in patients who will undergo unilateral inguinal herniorrhaphy operation…
- Conditions
- Postoperative Pain, Inguinal Hernia, Local Infiltration, Quality of Recovery
- Trial name
- NCT05847842
- Testing
- Anterior quadratus lumborum block, Transversus abdominis plane block, Local infiltration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Eskisehir Osmangazi University
Inguinal Hernias
Prospective, Randomized, Controlled Trial Comparing Self-Gripping and Conventional Mesh in Laparoscopic Totally Extra Peritoneal Inguinal Hernia Repair
This study is a single-center, prospective, randomized controlled trial designed to compare clinical outcomes between self-gripping mesh and conventional mesh with limited tacker fixation in laparoscopic totally extraperitoneal…
- Trial name
- NCT07350187
- Testing
- Self-gripping mesh (Progrip™), Conventional mesh with tacker fixation (Parietex™)
- Where
- South Korea
- Volunteers
- 95 people
- Sponsor
- Chungnam National University Hospital
Patients Undergoing Laparoscopic Inguinal Hernia Repair
The Effect of Cold Vapor on Dyspnea, Thirst, Nausea, and Physiological Parameters in the PACU After Laparoscopic Inguinal Hernia Surgery
Cold vapor application is considered a promising intervention with the potential to alleviate side effects associated with anesthesia and surgery in the postoperative period.
- Trial name
- NCT07273162
- Testing
- Cold Vapor
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- TC Erciyes University