Clinical trials: Hernia
Hernia, Wound Infection
Suture Techniques to Reduce the Incidence of The inCisional Hernia
The objective of the study is reduction of the incidence of the most frequent complication of abdominal surgery, incisional hernia.
- Conditions
- Hernia, Wound Infection, Burst Abdomen, Pain
- Trial name
- STITCH (NCT01132209)
- Testing
- Closure of the abdominal wall after midline incisions
- Where
- Netherlands
- Volunteers
- 576 people
- Sponsor
- Erasmus Medical Center
Incisional Hernia
Reducing the Incidence of Incisional Hernia After Stoma Closure Using a Prophylactic Mesh
Background: Preliminary studies have shown that application of a prophylactic mesh during stoma closure reduces the incidence of incisional hernia at site of stoma closure.
- Trial name
- PROMESH (NCT04510558)
- Testing
- Stoma closure with non-resorbable mesh (ULTRAPRO Advanced Mesh, Ethicon, Johnson & Johnson) in the sublay position, Stoma closure without mesh
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Hernia Incisional Ventral
Management Of Large Incisional Hernia, Double Mesh Modification Of Chevrel's Technique Versus On Lay Mesh Hernioplasty
comparison between two groups of large midline incisional hernia, the first group managed by double mesh modification of chevrel's technique the second one managed by conventional onlay mesh repair
- Trial name
- NCT04430816
- Testing
- double mesh modification of chevrel's technique, on lay mesh hernioplasty
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Zagazig University
Inguinal Hernia Bilateral, Postoperative Pain
M-TAPA vs OSTAP for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the postoperative analgesic efficacy of M-TAPA block and OSTAP block in patients undergoing laparoscopic inguinal hernia repair.
- Trial name
- NCT07522853
- Testing
- Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA), Oblique Subcostal Transversus Abdominis Plane Block (OSTAP), Standard Analgesia use (paracetamol, contramal)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Primary Unilateral Inguinal Hernia
SIngle Port vs Standard TEP for Primary Inguinal Hernia Repair
This study is carried out to determine if laparoscopic inguinal TEP repair of the hernia using a mesh carried out with only 1 port (hole) results in the reduction of post- operative pain and use of painkillers, shorter hospital…
- Trial name
- LESSTEP (NCT02302937)
- Testing
- Group A will undergo laparoscopic TEP inguinal hernia repair with 3 ports (10 mm , and 2 ports of 5 mm ), Group B will undergo laparoscopic TEP inguinal hernia repair with a single port
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Parastomal Hernia
Trial Concerning the Frequency of Parastomal Hernia With or Without a Mesh
Specific aim: To compare patients with colostomies with or without mesh at the primary operation. Primary endpoint is the incidence of parastomal hernia requiring surgery.
- Trial name
- STOMAMESH (NCT00917995)
- Testing
- Polypropylene Mesh, density 25-40g/square meter
- Where
- Sweden
- Volunteers
- 241 people
- Sponsor
- Norrbottens Lans Landsting
Ventral Hernia
Laparoscopic Ventral Hernia Repair by Heavy Weight or Lighter Weight Mesh (COMPOSIX-trial)
1. General antibiotic prophylaxis: cefazoline (Cefacidal™) 2 gram iv administered 30 minutes before surgery 2. Laparoscopic surgery at least 5 cm overlap (mesh diameter should exceed hernia size by at least 10 cm) with or without…
- Trial name
- NCT00573105
- Testing
- Laparoscopic Ventral hernia repair by heavy weight mesh, Laparoscopic Ventral hernia repair by lighter weight mesh
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- University Hospital, Ghent
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Pain, Postoperative, Analgesia
Comparison of Postoperative Analgesic Efficacy of Caudal Block Versus Spinal Block With Levobupivacaine for Inguinal Hernia in Children
Neuraxial analgesia may improve postoperative outcomes for high-risk children who are susceptible to respiratory complications (e.g. post-operative apnea).
- Trial name
- NCT05117281
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hernia of Abdominal Wall, Biologic Mesh
Abdominal Wall Repair With Strattice in Germany: a Cohort Study
Incisional hernia is the most frequently seen long term complication in surgery causing much morbidity and even mortality in patients.
- Conditions
- Hernia of Abdominal Wall, Biologic Mesh, Strattice
- Trial name
- BASE cohort (NCT02168231)
- Testing
- Complex abdominal wall repair Strattice
- Where
- 6 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Erasmus Medical Center
Inguinal Hernia
QOL in Incarcerated Inguinal Hernias: TAPP Vs Open Repair
To determine if there is a difference in the quality of life in between patients who undergoes laparoscopic transabdominal pre-peritoneal (TAPP) or modified Lichtenstein hernioplasty
- Trial name
- NCT02788812
- Testing
- Open modified Lichtenstein repair, Laparoscopic TAPP inguinal hernia repair
- Volunteers
- 100 people
- Sponsor
- Sarawak General Hospital
Gastroschisis
Direct Peritoneal Resuscitation in Gastroschisis
This is a prospective, double-arm study designed to evaluate the tolerability of direct peritoneal resuscitation (DPR) in neonates with gastroschisis.
- Trial name
- NCT03205553
- Testing
- SoC Staged Silo Closure, Peritoneal Dialysis Solution/Dextrose 1.5%
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Arkansas
Gastroschisis
Fetal Repair of Complex Gastroschisis: A Safety and Feasibility Trial
The goal of this clinical trial is to evaluate the safety and feasibility of fetal repair of complex gastroschisis (GS) via a fetoscopic surgical approach by assessing maternal, fetal, neonatal, and infant outcomes in a cohort of…
- Trial name
- NCT05704257
- Testing
- fetoscopy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Congenital Diaphragmatic Hernia
Safety and Efficacy of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia
The purpose of this study is to evaluate the safety and efficacy of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in cases of severe Congenital Diaphragmatic Hernia (CDH).
- Trial name
- NCT06946576
- Testing
- Fetoscopic Endoluminal Tracheal Occlusion (FETO) Procedure
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Oregon Health and Science University
Hernia, Inguinal Hernia
A Clinical Study to Evaluate the Clinical Performance and Safety of LiquiBand FIX8® Versus AbsorbaTack™ for Hernia Mesh Fixation and Peritoneal Closure in Groin Hernia Repair
This is a multi-center, randomized controlled trial of 284 subjects (142 in each group). Patients will be blinded to the fixation method used.
- Conditions
- Hernia, Inguinal Hernia, Femoral Hernia, Groin Hernia
- Trial name
- NCT04009213
- Testing
- LiquiBand FIX8®, AbsorbaTack™
- Where
- 6 sites in United States
- Volunteers
- 284 people
- Sponsor
- Advanced Medical Solutions Ltd.
Low Back Pain, Sciatica
Long-Term Course of Korean Medicine Treatment for Lumbar Disc Herniation
This observational study will assess the long-term course and effect of Korean medicine treatment in lumbar intervertebral disc herniation patients who received integrative Korean medicine treatment for 24 weeks as part of a…
- Conditions
- Low Back Pain, Sciatica, Intervertebral Disc Displacement
- Trial name
- NCT03426215
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Disc Herniation, Postoperative Pain
Comparison of the Effects of Quadratus Lumborum Block and Retrolaminar Block on Postoperative Pain in Lumbar Disc Herniation Surgery
This study aims to compare the analgesic efficacy of quadratus lumborum block (QLB) and retrolaminar block (RLB) in patients undergoing lumbar disc herniation surgery.
- Trial name
- NCT07166250
- Testing
- Quadratus Lumborum Block, Retrolaminar Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli University
Lumbar Disc Herniation, Obstructive Sleep Apnea Risk Management
Daytime vs Evening Rehabilitation in Lumbar Disc Herniation Patients at High Risk for Obstructive Sleep Apnea
Lumbar disc herniation is a common musculoskeletal condition that negatively affects quality of life, physical function, and daily activities.
- Trial name
- REHAB-TIME (NCT07522021)
- Testing
- Physiotherapy and Exercise Program
- Volunteers
- 60 people
- Sponsor
- Mardin Artuklu University
Hiatal Hernia
Biologic Versus Synthetic Mesh for Treatment of Paraesophageal Hernia
The investigators propose a randomized, single blinded controlled trial to compare the use of synthetic versus biologic mesh in hiatal hernia repair, two currently accepted standard of care surgical modalities.
- Trial name
- NCT02242526
- Testing
- Parietex™ Composite Hiatal Mesh, North Haven, CT, Biodesign™ Surgisis® Graft, Cook Medical, Bloomington
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Incisional Hernia, Ventral Hernia
Watchful Waiting of Incisional Hernias
This study is being conducted to gain a better understanding of the quality of life for patients with a diagnosis of primary and recurrent incisional hernias and 1) who decline to have surgery to repair the hernia or 2) patients…
- Conditions
- Incisional Hernia, Ventral Hernia, Umbilical Hernia
- Trial name
- NCT00351455
- Testing
- smoking cessation, tighter diabetic control, diet and exercise program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine