Clinical trials: Hiatus Hernia
Achalasia, Paraesophageal Hernia
Minimally Invasive Surgery of the Gastro-esophageal Junction
This study will assess short and long term outcomes of individuals undergoing minimally invasive surgery of the gastro-esophageal junction (MISGEJ).
- Conditions
- Achalasia, Paraesophageal Hernia, GERD, Epiphrenic Diverticula
- Trial name
- MISGEJ (NCT01799967)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Hiatal Hernia
Miromatrix Biological Mesh for Hiatal Hernia Repair
Miromatrix Medical has developed MIROMESH® - a new, noncrosslinked, acellular mesh derived from the highly vascularized porcine liver.
- Trial name
- NCT02436681
- Testing
- MIROMESH
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Miromatrix Medical Inc.
Gastroesophageal Hernia
Hill-grade Knowledge Via Integrated Neural-network for Gastroscopy
The Hill classification, also known as the Hill grade, is a system used to classify the severity of gastroesophageal valve incompetence, specifically related to gastroesophageal reflux disease (GERD) and hiatal hernia.
- Trial name
- HillKING (NCT06040723)
- Testing
- EndoMind
- Where
- Germany
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Obesity, Hiatal Hernia
Comparative 3-year Study of Nissen-sleeve vs. Sleeve Plus Cruroplasty in Obese Patients With Hiatal Hernia
The success of laparoscopic sleeve gastrectomy (LSG) is not only due to its proven efficacy in the treatment of obesity and associated to comorbidities in the short and long term, but also because it is considered as less…
- Trial name
- HH-N Sleeve (NCT06835790)
- Testing
- Ph-measurement, Questionnaires, gastroduodenal transit
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Elsan
Hiatus Hernia, Gastreoesophageal Reflux Disease
Phrenoesophageal Ligament Reconstruction With Mesh
Introduction: The phrenoesophageal ligament (PEL) is a crucial structure that attaches the esophagus to the diaphragm, allowing for independent movement during respiration and swallowing.
- Trial name
- NCT07251010
- Testing
- Phrenoesophageal Ligament Reconstruction with Mesh: A New Approach to Hiatal Hernia Repair (Alinasser's Technique), Classic approach
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Clinical Trial Aseer
Hernia, Paraesophageal
Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo
We aim to study the impact of perioperative IV lidocaine on postoperative pain control in patients undergoing paraesophageal hernia repair. This is in the context of an established ERAS protocol.
- Trial name
- PEH (NCT04096170)
- Testing
- IV lidocaine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hiatal Hernia, Sleeve Gastrectomy
Laparoscopic Hiatal Hernia Repair With Mesh Cruroplasty
The study you're referring to explores a surgical strategy for patients undergoing Laparoscopic Sleeve Gastrectomy (LSG) who also have a Hiatal Hernia (HH).
- Trial name
- NCT07491003
- Testing
- Hiatal Hernia (HH) repair using mesh cruroplasty during a Laparoscopic Sleeve Gastrectomy (LSG)
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Zagazig University
Hernia, Hernia Abdominal Wall
Image-Guided Herniorrhaphy Study
This pilot clinical study will evaluate the safety and effectiveness of a new image-guided, needle-based approach for repairing abdominal or groin hernias in adults who are unable or unwilling to undergo traditional open or…
- Conditions
- Hernia, Hernia Abdominal Wall, Ventral Hernia, Inguinal Hernia
- Trial name
- NCT07267494
- Testing
- Image-Guided Herniorrhaphy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Hiatal Hernia, Paraesophageal Hernia
Study of Paraesophageal Hernia Repair With Small Intestine Submucosa
In 2006 this research group reported their initial findings of a multi-center prospective trial comparing primary repair and primary repair buttressed with a biologic mesh made from porcine small intestinal submucosa (SIS).
- Trial name
- PEH (NCT00786084)
- Where
- 4 sites in United States
- Volunteers
- 108 people
- Sponsor
- University of Washington
Paraesophageal Hernia
Short Esophagus in Type II-IV Hiatus Hernia
Background: The existence, diagnosis and treatment of short esophagus is one of the controversies of the past which has recently re-emerged.
- Trial name
- SEHH (NCT01587859)
- Testing
- laparoscopic surgery
- Where
- 2 sites in Italy
- Volunteers
- 34 people
- Sponsor
- University of Bologna
Hernia, Paraesophageal Hernia
Randomized, Prospective Controlled Trial of Paraesophageal Hernia Repair With Small Intestinal Submucosa (SIS)
The purpose of this randomized study is to determine whether a type of mesh derived from a layer of pig small intestine (SIS) is of benefit in treating paraesophageal hernias versus standard surgical suture repair.
- Trial name
- NCT00272922
- Testing
- hernia repair
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Cook Group Incorporated
Paraesophageal Hernia
Gastropexy in the Repair of Patients With Paraesophageal Hernias
Patients scheduled for surgery for primary paraesophageal herniation are randomized to either conventional surgical hernia repair or with the addition of gastropexy.
- Trial name
- PEH3 (NCT06107634)
- Testing
- Gastropexy, Paraesophageal hernia repair
- Where
- 6 sites in Sweden
- Volunteers
- 150 people
- Sponsor
- Ersta Diakoni
Hiatal Hernia Large
Recurrence Rate After Laparoscopic Repair of Large Hiatal Hernia
Patients who underwent laparoscopic repair of large hiatal hernias and anterior fundoplication with mesh are examined for their recurrence rate one year after surgery.
- Trial name
- NCT03025932
- Testing
- repair of giant hiatal hernia with mesh and anterior fundoplication
- Volunteers
- 200 people
- Sponsor
- Prof Urs Zingg
Paraesophageal Hernia
Effect of Hernia Sac Excision on Crural Tension in Paraesophageal Hernia Repair
Paraesophageal hernia can cause significant clinical symptoms, including reflux, chest pain, nausea, regurgitation, and even life threatening conditions such as bowel obstruction, and gastric volvulus.
- Trial name
- NCT07197619
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Corewell Health West
Hiatal Hernia
Impact of Biosynthetic Mesh on Paraesophageal Hernia Repair
The aim of this study is to find out if using a certain kind of mesh can reduce the chances of hiatal hernias coming back after anti-reflux surgery.
- Trial name
- NCT06444347
- Testing
- Biosynthetic Mesh, Hiatal Hernia Repair
- Where
- 6 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Hiatal Hernia With Gastroesophageal Reflux Disease, Gastroesophageal Reflux
Complications, Outcomes and Revisions Following Hiatal Hernia Repair With MIROMESH
Investigator will identify a consecutive cohort of patients who have undergone a hiatal hernia repair and are at least 6 months post index procedure.
- Conditions
- Hiatal Hernia With Gastroesophageal Reflux Disease, Gastroesophageal Reflux, GERD
- Trial name
- NCT03735862
- Testing
- Hepatic derived surgical matrix
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Miromatrix Medical Inc.
Gastroesophageal Reflux Disease
True Short Esophagus in Gastroesophageal Reflux Disease
True short esophagus is controversial in surgery for gastroesophageal reflux disease and hiatus hernia. Recently, it was published that extensive esophageal mobilization achieved an esophageal length adequate to perform around…
- Trial name
- NCT03848494
- Testing
- Surgery
- Volunteers
- 311 people
- Sponsor
- University of Bologna
Gastroesophageal Reflux Disease
Antireflux Ablation Therapy (ARAT) Vs Antireflux Mucosectomy (ARMS) In The Management Of Gastroesophageal Reflux Disease
Gastroesophageal reflux disease has a high global prevalence, proton pump inhibitors are the cornerstone in the management but 10-20% of the patients are refractory to these, surgical treatment being an option of treatment in…
- Trial name
- NCT04036942
- Testing
- Ablation of the gastroesophageal junction with hybrid argon plasma, mucosectomy with band of the gastroesophageal junction
- Where
- Mexico
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Hiatal Hernia
Usage of Biological Patch Versus Plastic in the Laparoscopic Repair of Hiatal Hernias
The purpose of this study is to observe the effective and safety in the laparoscopic repair of hiatal hernia using biological patch versus plastic.
- Trial name
- NCT02328248
- Testing
- Biological patch
- Volunteers
- 150 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Paraesophageal Hernia, GERD
Mesh Vs Pledgets for Repair of Paraesophageal Hernia
The goal of this clinical trial is to compare whether the use of Ovitex mesh provides superior reduction in 2-year recurrence compared to pledgeted suture closure (no mesh) for patients undergoing paraesophageal hernia repair at…
- Trial name
- NCT05974722
- Testing
- OviTex Mesh, Pledgeted sutures
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- David Krpata