Clinical trials: High Risk Sex Behavior
Unsafe Sex, Risk-Taking
Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men and Using Oral Tenofovir Disoproxil Fumarate/ Emtricitabine (TDF/FTC) for HIV Pre-Exposure Prophylaxis (PrEP)
The study ANRS 174 Doxyvac is a clinical trial that will use Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex with Men and using oral TDF/FTC for HIV Pre-Exposure Prophylaxis (PrEP) and…
- Trial name
- DOXYVAC (NCT04597424)
- Testing
- Experimental: doxycycline, Bexsero® vaccine
- Where
- 9 sites in France
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
PSA, Unprotected Sex
Promoting CSD500 Use Among Women in Established Relationships
Globally, women in established relationships remain at risk for unintended pregnancy and sexually transmitted infections (STIs), including HIV.
- Trial name
- NCT02934620
- Testing
- CSD500 Condom, Standard Condom, Condom Counseling
- Where
- Vietnam
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University
HIV, Sexually Transmitted Diseases
Prevention of HIV and STDs in Drug Using Women
Women Teaching Women (WTW) is proposed by a team of Washington University investigators who have focused on HIV prevention efforts among out-of-treatment injecting drug users (IDUs) and crack cocaine users, since 1988.
- Conditions
- HIV, Sexually Transmitted Diseases, Substance Abuse
- Trial name
- WTW (NCT01235091)
- Testing
- NIDA Cooperative Agreement Standard Intervention plus HIV/STD testing, Standard Intervention plus Well-Woman Exam, Standard Intervention plus Well-Woman Exam and Peer-Delivered Intervention
- Volunteers
- 501 people
- Sponsor
- Washington University School of Medicine
Anal Cancer, Squamous Intraepithelial Lesions
Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis
This study aims to learn more about anal cancer risk in men who have sex with men (MSM) who are using Pre-Exposure Prophylaxis (PrEP) to prevent HIV.
- Conditions
- Anal Cancer, Squamous Intraepithelial Lesions, HSIL, High Grade Squamous Intraepithelial Lesions, LSIL, Low-Grade Squamous Intraepithelial Lesions
- Trial name
- SCOPE (NCT07029152)
- Testing
- Anal smear, Self-administered questionnaire, EQ-5D-5L questionnaire
- Where
- 8 sites in Belgium
- Volunteers
- 296 people
- Sponsor
- Universitair Ziekenhuis Brussel
Unprotected Sex, Contraceptive Usage
The Evaluation of Pulse: A Mobile Health App and Teen Pregnancy Prevention Program
This study uses a randomized controlled design to evaluate the efficacy of a new mobile app, Pulse, in reducing the incidence of unprotected sex among young women.
- Conditions
- Unprotected Sex, Contraceptive Usage, Reproductive and Sexual Health Care Utilization
- Trial name
- NCT03253783
- Testing
- Pulse
- Where
- United States
- Volunteers
- 1,304 people, healthy volunteers welcome
- Sponsor
- Healthy Teen Network
Sexual Dysfunctions, Psychological, High Risk Pregnancy
Sexual Function Changes in High-Risk Pregnancies
Sexual Function Changes in High-Risk Pregnancies
- Conditions
- Sexual Dysfunctions, Psychological, High Risk Pregnancy, Sexual Behavior
- Trial name
- NCT05093647
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Unsafe Sex
MyLife MyStyle Evaluation Project
The purpose of the MyLife MyStyle Evaluation Project is to determine whether the MyLife MyStyle group-level intervention reduces HIV sexual-risk behaviors among 18- to 29-year-old African American men who have sex with men (MSM).
- Trial name
- MLMS (NCT01640392)
- Testing
- MyLife MyStyle group-level intervention
- Where
- United States
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- Los Angeles County Department of Public Health
HIV Infections, Depression
Bupropion For Reducing High-Risk Behaviors in Depressed Men Who Have Sex With Men (MSM)
The primary purpose of this study was to test the whether high-risk, HIV-seronegative persons with mild-to-moderate depression would be more likely to adopt protective behavior change when provided with pharmacotherapy for their…
- Trial name
- NCT00285584
- Testing
- Bupropion
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- NYU Langone Health
Serologic Response of Syphilis, Early Syphilis
Comparisons of Serologic Response of Early Syphilis
Syphilis and HIV are prone to occur concomitantly and the two diseases share several modes of acquisition and risk factors such as men who have sex with men (MSM), sexual workers, intravenous drug users, previous history of…
- Conditions
- Serologic Response of Syphilis, Early Syphilis, High Risk Behavior
- Trial name
- NCT01944358
- Where
- 2 sites in Taiwan
- Volunteers
- 1,128 people
- Sponsor
- National Taiwan University Hospital
HIV
Diagnostic of Human Immunodeficiency Virus (HIV) and Other Sexual Transmission Diseases (STD) in High Risk Populations: Men Who Have Sex With Men (MSM) Users of Chemsex
The main objective is to offer diagnostic tests for HIV, HCV and other STD in the risk group of men having sex with men (MSM) users of Chemsex
- Trial name
- Care_ChemS (NCT03546140)
- Volunteers
- 500 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Stigma, Social
Project Orleu: Reducing Intersectional and HIV Stigma Among Health Care Providers and High Risk Women Who Use Drugs in Kazakhstan
Suboptimal linkage to and retention in HIV prevention and care is prevalent among high-risk women who use or inject drugs in both the US and globally, including high HIV incidence contexts like Kazakhstan; addressing HIV and…
- Trial name
- NCT06932796
- Testing
- Health Care Provider Stigma Training and Clinic-Based Messaging Campaign
- Where
- Kazakhstan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Columbia University
Unsafe Sex, Risk Reduction
Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)
The goal of this study is to develop and test a program to help Black men who have sex with men and women reduce their chances of getting or giving HIV infection to their sex partners.
- Trial name
- Power (NCT01376895)
- Testing
- PROJECT POWER, Power Health
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Pregnancy, Sexually Transmitted Diseases
Randomized Evaluation of a Multi-Component, Rights-Based Sexuality Education Initiative for High School Students
This study examines the effectiveness of the Sexuality Education Initiative (SEI), a comprehensive, multi-component, rights-based sexuality education program developed and implemented by Planned Parenthood Los Angeles for high…
- Trial name
- SEI (NCT02009046)
- Testing
- SEI Classroom Curriculum, Control Classroom Curriculum, SEI Curriculum + 3 School Components
- Where
- United States
- Volunteers
- 1,909 people, healthy volunteers welcome
- Sponsor
- Public Health Institute, California
Sexual Behavior, Unprotected Sex
Protecting Our Future Generation: Promotion of Protective Sexual Health Practices Among Native American Youth and Young Adults Through an Assets-based Self-care Intervention
The aim of this research protocol is to test the efficacy of a self-care intervention through a randomized controlled trial (RCT), for increasing protective sexual health behaviors among youth in the participating Native American…
- Conditions
- Sexual Behavior, Unprotected Sex, Gonorrhea, Chlamydia
- Trial name
- NCT03895320
- Testing
- Sexual Health Risk Assessment, Sexual Health Score, Sexual Health Messaging
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
High-risk Sex
The SPOT Project : Motivational Interviewing in Conjunction With Rapid HIV Testing
In 2009, a team of researchers from Montreal, Canada, implemented SPOT, an intervention aimed at reducing HIV transmission among men who have sex with men by offering rapid HIV testing in a community setting.
- Trial name
- NCT01931345
- Testing
- Motivational Interviewing Counseling, Standard counseling
- Where
- Canada
- Volunteers
- 900 people
- Sponsor
- Université du Québec a Montréal
Sexual Behavior, Unprotected Sex
Evaluation of Manhood 2.0: A Community-Based Teen Pregnancy Prevention Program for Young Men
Manhood 2.0 is a male-only group-level intervention, delivered over 13 hours, based on social cognitive theory, social norm theory, theory of gender and power, and the theory of reasoned action.
- Trial name
- NCT04962802
- Testing
- Manhood 2.0, Post-High School Readiness
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Child Trends
HIV Preexposure Prophylaxis
Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Are at High Risk for HIV-1 Infection (MK-8591-024)
The main purpose of the study is to evaluate the safety and tolerability of oral Islatravir (ISL) once monthly (QM) as Preexposure Prophylaxis (PrEP) in cisgender men who have sex with men (MSM) and transgender women (TGW) who…
- Trial name
- Impower-024 (NCT04652700)
- Testing
- ISL, FTC/TDF, FTC/TAF
- Where
- 25 sites in United States, Brazil and 5 more
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
HIV Infection Primary, Hepatitis, Viral, Human
Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Pre-exposure prophylaxis (PrEP) based on tenofovir represents a considerably new preventive intervention that has shown to significantly decrease the number of HIV infections while it enables early diagnosis of HIV and other…
- Conditions
- HIV Infection Primary, Hepatitis, Viral, Human, Sexually Transmitted Infections, Excluding HIV and Hepatitis
- Trial name
- SeVIHPrEP (NCT05492565)
- Testing
- Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Transgenderism
Evaluation of an Adaptative, Multidisciplinary, Reach-out Program, Facilitating Pre Exposition HIV Prophylaxis (PrEP) Prescription and Retention in Care, in a Group of Trans Womens (TW) at High Risk of HIV Infection.
Evaluation of an adaptative, multidisciplinary, reach-out program, facilitating pre exposition HIV prophylaxis (PrEP) prescription and retention in care, in a group of trans womens (TW) at high risk of HIV infection.
- Trial name
- PrEP à porter (NCT05415930)
- Testing
- Psychosocial assistance, Medical care, Legal-Administrative Assistance
- Volunteers
- 100 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba