Clinical trials: High Risk of Stroke
Cardiac Disease
Impact of High Mechanical Index Ultrasound Impulses on Left Ventricular Stroke Volume With Intravenous Microbubbles
This study will investigate whether applying high mechanical index (MI) impulses from a diagnostic ultrasound transducer when using ultrasound enhancing agent (UEA) microbubble infusion will result in subclinical improvement in…
- Trial name
- MI (NCT05700032)
- Testing
- high MI impulses, low MI impulses
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Atrial Fibrillation, Stroke
Wearable ECG for AF Screening and Stroke Risk Assessment
This study aims to evaluate the application of wearable ECG garments in atrial fibrillation (AF) screening and stroke risk assessment.
- Trial name
- NCT06907264
- Testing
- Wearable ECG Garment for Continuous Atrial Fibrillation Screening and Stroke Risk Assessment
- Where
- 2 sites in China
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Hypertension, Coronary Disease
Analyzing How Genetics May Affect Response to High Blood Pressure Medications
High blood pressure is one of the most common health problems in the United States. There are many medications to treat high blood pressure, but there is a large variance in how people respond to these medications.
- Conditions
- Hypertension, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00563901
- Where
- 2 sites in United States
- Volunteers
- 37,939 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Stroke
Non-Invasive Brain Stimulation
The study focusses on utilizing neuroimaging modalities, including Electroencephalography (EEG) and Functional Magnetic Resonance Imaging (fMRI) to study the impact of non-invasive brain stimulation on the prefrontal cortex…
- Trial name
- NCT04318522
- Testing
- Transcranial Direct Current Stimulator
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Heart Diseases
Identifying Genes That May Increase the Risk for Heart Disease in African Americans
Heart disease and stroke disproportionately affect African Americans in the United States. These conditions are likely caused by both environmental and genetic factors.
- Trial name
- NCT00344136
- Where
- United States
- Volunteers
- 5,302 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Swimming, Coordination Lack
Swimming Economy in Swimmers and Paraswimmers as a Function of SR(Stroke Rate) and V(Velocity) Manipulations (NePTUNE-3)
The competitive swimming and open water swimming events are scheduled for the 2024 Paris Olympic and Paralympian Games. Generally associated with a non-neglectable number of medals in the last Olympics, swimming performance…
- Conditions
- Swimming, Coordination Lack, Oxygen Consumption, Lactic Acid Blood Increased
- Trial name
- NePTUNE-3 (NCT05011591)
- Testing
- Swimming economy
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Rouen Normandie
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Diabetes Mellitus, Type 2, Metabolic Syndrome X
Meta-analyses of Impotrant Food Sources of Sugars and Incident Cardiometabolic Diseases
There is an urgent need for stronger evidence to support recommendations for the role of sugars in diabetes and related cardiometabolic diseases.
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Syndrome X, Hypertension, Cardiovascular Diseases
- Trial name
- NCT02702375
- Testing
- Fructose-containing Sugars
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke, High Blood Pressure
Chronic Effect of Mat Pilates on Neuromotor, Cardiovascular Functions and Inflammatory Markers in Individuals Post-Stroke Stroke and High Blood Pressure
The Pilates method aims to develop conscious control of body movements. In the literature there are studies that relate the method to postural stabilization, joint rehabilitation, treatment of low back pain, cancer and chronic…
- Trial name
- NCT06241339
- Testing
- Mat Pilates
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Stroke
Effect of Multisite High-definition Transcranial Direct Current Stimulation Targeting Sensorimotor Network
Transcranial direct current stimulation (tDCS) has been applied to facilitate cortical excitability in stroke populations, as increasing evidence suggests that clinical recovery from stroke is attributed to neuroplastic…
- Trial name
- NCT06648954
- Testing
- multisite HD-tDCS, Conventional tDCS
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke, Cramp
The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability
In the present project, the investigators aim at proposing innovative ways of investigating spinal motoneuron hyperexcitability to counteract the associated impairments by using wide pulse high frequency neuromuscular electrical…
- Conditions
- Stroke, Cramp, Restless Legs Syndrome, Healthy Volunteers
- Trial name
- MnHyperex (NCT05908214)
- Testing
- wide pulse high frequency neuromuscular electrical stimulation training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Acute Stroke, Transient Ischemic Attack
The Recurrence Study
The primarily goal of the research is to better understand progression of disease in patients who present with an acute stroke to the Hamad General Hospital (HGH) stroke and Transient Ischemic Attack (TIA) clinic.
- Trial name
- NCT03244215
- Testing
- Corneal Confocal Imaging, Magnetic resonance Imaging, Blood sample
- Where
- Qatar
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Exertional Heat Illness, Hydration Status
Comparing Risk of Heat Illness Based on Peak Core Temps During Preseason Football Camp Across 3 Different Age Levels
To collect field data in professional, collegiate, and high school football players to determine how they respond physiologically to the rigors of preseason training environment.
- Trial name
- NCT01954537
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pneumonia, Urinary Tract Infection
Identification of Admission High Risk Elderly
Objective: The study aim to establish high risk admission model and readmission model for elderly in Taiwan. Method: Investigators compare the clinical, epidemiological, and socioeconomic characteristics of admitted patients…
- Conditions
- Pneumonia, Urinary Tract Infection, Stroke
- Trial name
- NCT01934426
- Where
- Taiwan
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stroke, Myocardial Infarction
Predictors of Blood Pressure Control and Associations With Cardiovascular Diseases in Individuals With High Blood Pressure: a CALIBER Study
Current guidelines for the clinical management of hypertension in adults recommend to achieve and maintain blood pressure levels of <140/90 mmHg.
- Conditions
- Stroke, Myocardial Infarction, Stable Angina Pectoris, Heart Failure
- Trial name
- NCT02285322
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Neurologic Disorder, Parkinson Disease
High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners
Individuals with and without neurologic diagnoses greatly benefit from participation in regular exercise but the majority are physically inactive.
- Conditions
- Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida
- Trial name
- SHIFT-AR (NCT05951985)
- Testing
- HIFT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Stroke
Clinical Relevance of the HD sEMG Signals in the Post-stroke Rehabilitation
The goal of this clinical trial is to learn about the WPM-SEMG-V2 device (Wireless Portable and Multi-Channel, WPM) designated to acquire high-density (HD) surface electromyography (sEMG) signals in healthy volunteers and…
- Trial name
- NCT05849896
- Testing
- Acquisition of HD sEMG signals using the WPM-SEMG device
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alain Kaelin
MACE, Atrial Fibrillation (AF)
throMboembolic Risk Associated To High atrIal Fibrillation riSk
Cardiovascular diseases are the leading cause of mortality from treatable conditions in the European Union and the second from preventable causes, with a standardized mortality rate of 257.8 deaths per 100,000 inhabitants.
- Conditions
- MACE, Atrial Fibrillation (AF), Quality-adjusted Life-years, Electronic Health Records
- Trial name
- MATHIAS (NCT07441759)
- Testing
- AI_MATHIAS
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Stroke
Perturbed-balance Training During Treadmill Walking for Stroke Subjects
A control and a post-stroke subject with right-side chronic hemiparesis were studied. The post-stroke subject underwent 30 sessions of balance-perturbed training while walking on an instrumented treadmill where the Balance…
- Trial name
- BALANCESI (NCT03285919)
- Testing
- Balance Assessment Robot (BAR™)
- Where
- Slovenia
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia