Clinical trials: High-Flow Nasal Cannula
Hypoxic Respiratory Failure
Diaphragmatic Ultrasound to Predict the Therapeutic Effect of High-flow Nasal Cannula Oxygen Therapy
Follow-up was conducted for every patient requiring high-flow nasal cannula oxygen therapy in district 1 of the Intensive Care Department of Chenzhou NO.1 People's Hospital.
- Trial name
- NCT06336265
- Testing
- Diaphragm ultrasound
- Volunteers
- 269 people
- Sponsor
- Xingui Dai
Chronic Obstructive Pulmonary Disease (COPD)
High-flow Nasal Cannula Therapy for Stable Chronic Obstructive Pulmonary Disease (COPD)
This is a prospective, randomized crossover study for evaluation of the efficacy and safety of long-term nocturnal high-flow nasal cannula therapy with the myAIRVO2® in stable COPD patients with stage 2-4 of the Global Initiative…
- Trial name
- NCT02545855
- Testing
- High-flow nasal cannula therapy, Home oxygen therapy (HOT)
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Gastroscopy
High Flow Nasal Cannula in Patients Undergoing Gastroscopy
During gastroscopy, the insertion of the fiberscope and gastric distension required to perform the examination may induce modifications to respiratory mechanics, respiratory effort and breathing pattern.
- Trial name
- NCT05693298
- Testing
- High Flow Nasal Cannula, Conventional Oxygen Therapy
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University Magna Graecia
COPD Exacerbations, Acute Hypercapnic Respiratory Failure
HFNC vs. NIV in Acute COPD Exacerbations
The investigators investigated the efficacy and safety of High Flow Nasal Cannula (HFNC) at different flow rates compared to non-invasive ventilation (NIV) in patients presenting to the emergency department (ED) with acute…
- Conditions
- COPD Exacerbations, Acute Hypercapnic Respiratory Failure, Respiratory Failure
- Trial name
- HFNCstdy (NCT06495086)
- Testing
- NIV, HFNC-30, HFNC-50
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Haseki Training and Research Hospital
Severe Obesity Design as BMI > 35kg/m2
Preoxygenation Optimisation in Obese Patients
Oro-tracheal intubation in operating room in obese patients with BMI > 35kg/m2 remains a critical event. The aim of this study is to determine whether Nasal High Flow Therapy by nasal cannula Optiflow® is more efficient than the…
- Trial name
- PREOPTI-POOP (NCT03106441)
- Testing
- High flow oxygen therapy by nasal cannula. Optiflow®, Facial mask oxygenation in BIPAP ventilation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Acute Respiratory Failure, Acute-on-chronic Respiratory Failure
VICOR Study-High Frequency Chest Wall Oscillations (HFCWO) in Patients With Acute Respiratory Failure and Hypersecretion
The study aims to evaluates if the treatment with HFCWO Via The Vest® Airway Clearance System, in addition to standard care in critically ill patients admitted in the Respiratory Intensive Care Unit for acute respiratory failure…
- Conditions
- Acute Respiratory Failure, Acute-on-chronic Respiratory Failure, Airway Clearance Impairment
- Trial name
- VICOR2 (NCT05751707)
- Testing
- High Frequency Chest Wall Oscillations via The Vest® Airway Clearance System
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- Raffaele Scala
Endoscopic Ultrasound
High Flow Nasal Cannula Compared to Standard Oxygen for Endoscopic Ultrasound
The purpose of the study is to evaluate the use of high flow nasal cannula versus standard oxygen therapy for high-risk patients undergoing endoscopy procedures.
- Trial name
- NCT06704867
- Testing
- High flow nasal cannula
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Transmission, Patient Professional, High-flow Nasal Cannula
Investigate the Aerosol Particle Distribution During Aerosol Generating Procedures
Massive number of clinicians were infected during the outbreak of COVID-19, which raised the concerns of utilizing "aerosol generating procedures", particularly the use of high-flow nasal cannula, noninvasive ventilation…
- Trial name
- NCT04353531
- Testing
- High-flow nasal cannula, Surgical mask, bronchoscopy examination
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rush University Medical Center
Hypoxemia, Gastric Cancer (Diagnosis)
High-Flow Nasal Cannula Oxygenation During Sedated Gastrointestinal Endoscopy in Patients With Chronic Obstructive Pulmonary Disease
Hypoxemia is the most common adverse event during propofol sedation for gastrointestinal endoscopy in patients with chronic obstructive pulmonary disease (COPD) due to diminished pulmonary reserve.
- Conditions
- Hypoxemia, Gastric Cancer (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD), Esophageal Cancer
- Trial name
- NCT07791979
- Testing
- High-flow nasal cannula
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhejiang University
Critically Illness
The Efficiency of HHHFNC Between Unheated Oxygen Therapy in Difficult Weaning Patients After Extubation in RCC
The purpose of this study is to assess the efficacy of Heated Humidified High-Flow Nasal Cannula compared with noninvasive positive-pressure ventilation in the prevention of extubation failure in patients with prolonged…
- Trial name
- HHHFNC (NCT04564859)
- Testing
- Heated Humidified High-Flow Nasal Cannula
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Postoperative Atelectasis, Bariatric Surgery Candidate
Can the Effects of High Flow Nasal Cannula Oxygenation on Postoperative Atelectasis be Evaluated With Lung Ultrasound
Evaluate the effects of high-flow nasal oxygen therapy on atelectasis in the perioperative period by lung ultrasound (LUS) in bariatric surgery patients.
- Conditions
- Postoperative Atelectasis, Bariatric Surgery Candidate, Ultrasound Therapy; Complications
- Trial name
- NCT03828513
- Testing
- High flow nasal cannula oxygen is applied, High flow nasal cannula oxygen is not applied
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
COPD
High Flow Nasal Cannula and Aerobic Capacity Training
The aim of this study is to compare exercise capacity in Chronic Obstructive Pulmonary Disease (COPD) patients before and after an 8 week pulmonary rehabilitation program.
- Trial name
- NCT02973945
- Testing
- High Flow Nasal Cannula, The Venturi Mask
- Where
- Argentina
- Volunteers
- 60 people
- Sponsor
- Hospital Italiano de Buenos Aires
Premature; Infant
Comparing of High Flow Nasal Cannula Versus Cpap for Initial Respiratory Stabilisation of Very Premature Infants
Non-invasive continuous positive airway pressure (CPAP) stabilizes premature newborns, but its optimal pressure is unknown. High-flow nasal cannula (HFNC) is an alternative that minimizes trigeminal stimulation but lacks precise…
- Trial name
- SIMPLSAFE3 (NCT06543589)
- Testing
- High-flow-nasal-cannula
- Volunteers
- 443 people
- Sponsor
- Charles University, Czech Republic
Chronic Obstructive Pulmonary Disease
HFNC Effect on BCSS in Patients With COPD
The primary objective of this study is to look for a correlation between the use of high-flow nasal cannula in the outpatient setting in patients with previous chronic obstructive pulmonary disease exacerbation and the change in…
- Trial name
- COPD (NCT02825043)
- Testing
- High-Flow Nasal Cannula
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Oklahoma
Acute Respiratory Failure
Effects of a New Interface for NIV on Respiratory Drive
This pilot physiologic randomized cross-over study was designed to investigate if, in patients with hARF, a new device combining high-flow oxygen through nasal cannula (HFNC) and continuous positive airway pressure (CPAP) reduces…
- Trial name
- NCT04619667
- Testing
- High Flow Nasal Cannula (HFNC), Continuous Positive Airway Pressure (CPAP)
- Volunteers
- 22 people
- Sponsor
- University Magna Graecia
Acute Hypoxemic Respiratory Failure, High-flow Nasal Cannula Oxygen
Modified HFNC Therapy for ARF Patients Undergoing Flexible Bronchoscopy
Acute respiratory failure (AFR) is a serious condition that requires prompt and appropriate intervention to prevent further deterioration and improve outcomes.
- Trial name
- NCT05759832
- Testing
- Modified HFNC oxygen therapy, Non-rebreathing reservoir mask
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Beijing Chao Yang Hospital
Respiratory Distress Syndrome in Premature Infant
Physiological Changes With High-Flow Nasal Cannula
To measure changes in physiologic parameters in extremely low birthweight (ELBW) infants on high-flow nasal cannula compared to nasal continuous positive airway pressure (nCPAP).
- Trial name
- NCT03700606
- Testing
- High flow nasal cannula, Nasal CPAP
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Sharp HealthCare
Respiratory Disease
Comparison of Oxygen Adminstration by Nasal Cannula and High Flow Cannula During Bronchoscopy
Randomized controled trial to compare oxygen desaturation during fiberoptic bronchoscopy using oxygen administered with nasal prongs and high flow nasal cannula.
- Trial name
- NCT03976167
- Testing
- Oxygen administration with Common nasal cannula, Oxygen administration with high flow nasal cannula, device Airvo2 Fisher and Pykel
- Volunteers
- 108 people
- Sponsor
- Hospital Son Espases
Carbon Monoxide Poisoning
The Role of High-flow Nasal Cannula Therapy in the Treatment of Acute Carbon Monoxide Poisoning
The aim of the study is to test whether oxygen therapy delivered through high-flow nasal cannula devices in patients admitted to the emergency department for acute carbon monoxide poisoning is superior to the non-rebreathing…
- Trial name
- NCT03818841
- Testing
- High-flow nasal cannula device, Non-rebreathing oxygen mask group
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
Healthy Volunteers
Examining the Effects of Nasal High Flow Oxygen Therapy Compared to Non-invasive Ventilation in Health Volunteers
Respiratory failure is characterized by low levels of oxygen and high levels of carbon dioxide in the blood which causes difficulty breathing.
- Trial name
- NCT03902639
- Testing
- Phase 1 and 2, Phase 3
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto