Clinical trials: High-flow Nasal Cannula Oxygen
Healthy
Comparison of Preoxygenation Techniques in Healthy Volunteers With Monitoring of End-tidal Oxygen Fraction (FeO₂) and Oxygen Reserve Index (ORI)
The objective of this physiological study is to compare two preoxygenation techniques (non-invasive ventilation combined with high-flow nasal oxygen versus non-invasive ventilation alone) by monitoring end-tidal oxygen fraction…
- Trial name
- OXYGAME1 (NCT07334041)
- Testing
- Preoxygenation with VNI + OHD, Preoxygenation with VNI
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Pediatric Asthma
High Flow Nasal Cannula Rates in Pediatric Asthma
This is a randomized, open-label, 3-armed feasibility trial will examine conventional oxygen therapy (COT) vs high flow nasal cannula at 4L/min flow vs HFNC at 2L/kg/min flow (max 60L/min) in moderate to severe pediatric asthma…
- Trial name
- NCT06379607
- Testing
- "High Flow" High Flow Nasal Cannula, "Low Flow" High Flow Nasal Cannula
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Critically Illness
The Efficiency of HHHFNC Between Unheated Oxygen Therapy in Difficult Weaning Patients After Extubation in RCC
The purpose of this study is to assess the efficacy of Heated Humidified High-Flow Nasal Cannula compared with noninvasive positive-pressure ventilation in the prevention of extubation failure in patients with prolonged…
- Trial name
- HHHFNC (NCT04564859)
- Testing
- Heated Humidified High-Flow Nasal Cannula
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Healthy Volunteers
Examining the Effects of Nasal High Flow Oxygen Therapy Compared to Non-invasive Ventilation in Health Volunteers
Respiratory failure is characterized by low levels of oxygen and high levels of carbon dioxide in the blood which causes difficulty breathing.
- Trial name
- NCT03902639
- Testing
- Phase 1 and 2, Phase 3
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Healthy Volunteers
Gas Composition in the Hypopharynx During High-flow or Standard Oxygen Therapy Through Face Mask in Healthy Volunteers
The COVID-19 pandemic has become a huge global problem, affecting all spheres of human life, resulting in enormous social, economic consequences and human tragedies.
- Trial name
- O2-OXIMETRY (NCT07019701)
- Testing
- High flow oxygen through nasal cannula and face mask and standard oxygen therapy through non-rebreather face mask, and measurement of oxygen and carbon dioxide fraction in the hypopharynx
- Where
- Russia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Cardiogenic Pulmonary Edema
Helmet CPAP Versus HFNC in Acute Cardiogenic Pulmonary Edema
This study objectively held to compare the physiological outcomes in the non-invasive (NIV) treatment of Acute Cardiogenic Pulmonary Oedema (ACPE) patients in the Emergency Department (ED) delivered by Helmet CPAP (hCPAP) and…
- Trial name
- HCPAPvsHFNC (NCT04005092)
- Testing
- hCPAP versus HFNC
- Where
- Malaysia
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital Raja Permaisuri Bainun
Pediatric
The Effect of Education on Nurses' Knowledge About High-flow Nasal Cannula Oxygen Therapy
This study was conducted to evaluate the oxygen therapy methods used in pediatric services and to specify the roles and responsibilities of nurses in the application of HFNC, which is one of these methods.
- Trial name
- NCT05362279
- Testing
- Training
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Sedation Complication
Comparison of High-Flow Nasal Cannula Oxygen Application and Classic Nasal Cannula Oxygen Application
Recently, sedation practices have increased for diagnostic and interventional procedures for children in non-operating rooms. On the other hand, the rate of respiratory complications especially in non-operating room sedation…
- Trial name
- NCT04472273
- Testing
- high-flow nasal cannula / classic nasal cannula
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
End-Expiratory Lung Impedance, Respiratory Rate
Asymmetrical High Flow Nasal Cannula and End-Expiratory Lung Impedance
Objective: The primary aim is to assess end-expiratory lung impedance (EELI) changes during the application of high-flow oxygen therapy using asymmetric nasal cannulae, comparing conditions with the mouth closed and open in…
- Conditions
- End-Expiratory Lung Impedance, Respiratory Rate, Diaphragm Thickness Fraction, Diaphragm Excursion
- Trial name
- EELI and AHFNC (NCT06674629)
- Testing
- High flow oxygen therapy
- Where
- Argentina
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Argentinian Intensive Care Society
Oxygen, pH
Comparison of the Effects of High-flow Nasal Cannula Oxygen and Jet Ventilation Techniques
Endoscopic microsurgical procedures of the larynx (direct examination-bx, microlaryngeal resection) require the anesthesiologist and surgeon to work in the same area throughout the procedure, and while ventilation is provided…
- Conditions
- Oxygen, pH, End-tidal Carbon Dioxide
- Trial name
- NCT05746949
- Testing
- oxygenization techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul University
High Flow Nasal Cannula
Work of Breathing and Oxygen Saturation in Infants Receiving High Flow Nasal Cannula (HFNC)
The purpose of this study is to compare work of breathing on different levels of high flow respiratory support on infants born between 27 and 37 weeks gestation.
- Trial name
- NCT03529994
- Testing
- Enrollment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Healthy Volunteers
Gas Composition in the Oropharynx During High-flow Oxygen Therapy Through Nasal Cannula in Healthy Volunteers
Observational, randomized studies and their meta-analyses have shown the high effectiveness of high-flow oxygen therapy through nasal cannulas, reaching 50-60% in acute hypoxemic respiratory failure.
- Trial name
- NCT06189716
- Testing
- High flow oxygen through nasal cannula
- Where
- Russia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Bronchoscopy,Oxygen
Modified HFNC Oxygen in Patients Undergoing Bronchoscopy.
The purpose of this study is to determine whether the Modified High-flow nasal cannula is effective in the oxygen of the patients undergoing bronchoscopy.
- Trial name
- NCT02606188
- Testing
- Modified High-flow nasal cannula, nasal cannula
- Where
- China
- Volunteers
- 812 people, healthy volunteers welcome
- Sponsor
- Haichao Li
Coronavirus Infection, Pneumonia, Viral
HFNC Treatment in COVID-19 Pneumonia
coronavirus disease 2019 related pneumonia is causing acute respiratory failure and this is the most common reason for ICU admission. We have several different way for respiratory support.
- Conditions
- Coronavirus Infection, Pneumonia, Viral, Acute Respiratory Failure
- Trial name
- NCT04424836
- Testing
- high flow nasal cannula device
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital