Clinical trials: Hip
Hip Surgery, Femoral Neck Fractures
Comparison of Lumbar Erector Spinae Plane Block and Spinal Anesthesia in Hip and Proximal Femur Surgery
Hip and proximal femur surgeries are commonly performed in elderly patients and require anesthetic techniques that provide adequate surgical anesthesia while minimizing the need for additional opioid administration.
- Trial name
- L-ESP-HIP Stud (NCT07427082)
- Testing
- Ultrasound-Guided Lumbar Erector Spinae Plane Block (L4), Spinal Anesthesia (L4-L5)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Gaziantep City Hospital
Total Hip Arthroplasty, Postoperative Pain
PENG, Suprainguinal Fascia Iliaca Block, and Control After Total Hip Arthroplasty
Total hip arthroplasty can cause significant pain after surgery. Regional anesthesia techniques, such as the pericapsular nerve group (PENG) block and the suprainguinal fascia iliaca plane block, may help reduce postoperative…
- Trial name
- NCT07879521
- Testing
- Pericapsular nerve group (PENG) block, Suprainguinal Fascia Iliaca Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Uludag University
Knee Osteoarthristis, Hip Osteoarthritis
Clinical Validation of SMARTDIAGO for Remote Functional Assessment of Musculoskeletal Conditions
Clinical validation of SMARTDIAGO, an artificial intelligence-based system for remote functional assessment of patients with musculoskeletal disorders and functional frailty.
- Conditions
- Knee Osteoarthristis, Hip Osteoarthritis, Spine Disease, Shoulder Disease
- Trial name
- SMARTDIAGO (NCT07880210)
- Testing
- SMARTDIAGO Remote Functional Assessment
- Where
- 2 sites in Chile
- Volunteers
- 350 people
- Sponsor
- University of Chile
Neurologic Diseases, Arthropathy of Knee
Experience of Use and Biopsychosocial Effects of Robotic and Virtual Reality Devices in Neuromotor Rehabilitation
The implementation of virtual reality (VR) and robotic devices in neuromotor rehabilitation has so far provided promising evidence in terms of efficacy throughout different clinical populations.
- Conditions
- Neurologic Diseases, Arthropathy of Knee, Arthropathy of Hip
- Trial name
- NCT05399043
- Testing
- Multidisciplinary Conventional Neuromotor Rehabilitation, Technology-based Rehabilitation
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Hip Fractures
Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture
The purpose of this study is to determine if patients with hip fractures who undergo cryoablation of the PENG have improved pain control 30 days from surgery when compared to those who have a fascia iliaca catheter.
- Trial name
- NCT06278987
- Testing
- PENG block and cryoablation, fascia iliaca compartment block
- Sponsor
- University of Minnesota
Primary Osteoarthritis, Cartilage Degeneration
DEXA Bone Density Analysis of the CoreHip® Prosthesis System
The goal of this interventional post-market follow-up study is to evaluate radiological changes in the diaphyseal bone density (Gruen Zones 3 and 4) within 24 months postoperative in patients treated with CoreHip® primary…
- Conditions
- Primary Osteoarthritis, Cartilage Degeneration, Osteoarthritis, Hip, Inflammatory Arthritis
- Trial name
- CODEX (NCT06632301)
- Testing
- Primary hip replacement with cementless stem
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Aesculap AG
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck
Z1 Hip System: Post-Market Clinical Follow Up Study
The objectives of this study are to confirm the early to mid- term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi- and primary total hip arthroplasty.
- Conditions
- Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
- Trial name
- NCT07104279
- Testing
- Z1 Femoral Hip System
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Greater Trochanteric Pain Syndrome, Greater Trochanteric Pain Syndrome of Both Lower Limbs
ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain
The goal of this clinical trial is to evaluate the safety and analgesic performance of the ReneuRx™ device in subjects with moderate to severe chronic lateral hip pain compared to subjects receiving treatment with corticosteroid…
- Conditions
- Greater Trochanteric Pain Syndrome, Greater Trochanteric Pain Syndrome of Both Lower Limbs, Lateral Hip Pain
- Trial name
- RENEU (NCT07568015)
- Testing
- Triamcinolone acetate, ReneuRx
- Where
- 11 sites in United States
- Volunteers
- 100 people
- Sponsor
- Brixton Biosciences, Inc.
Pain, Postoperative, Muscle Weakness
Low-Volume Pericapsular Nerve Group (PENG) Block With Dexamethasone vs Standard-Volume PENG Block After Total Hip Arthroplasty
The goal of this clinical trial is to compare two regimens of the pericapsular nerve group (PENG) block, an ultrasound-guided injection of local anaesthetic targeting the nerves supplying the front of the hip joint, for…
- Conditions
- Pain, Postoperative, Muscle Weakness, Arthroplasty, Replacement, Hip
- Trial name
- NCT07855341
- Testing
- Pericapsular nerve group (PENG) block, Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Osteoarthritis (Knee / Hip), Sarcopenia
Preoperative Muscle Stiffness, Functional Reserve, and Postoperative Quality of Recovery in Lower Extremity Arthroplasty
In elderly patients undergoing arthroplasty surgery, postoperative recovery quality is closely related to preoperative physical reserve. Sarcopenia and reduced muscle quality can increase postoperative complications.
- Conditions
- Osteoarthritis (Knee / Hip), Sarcopenia, Postoperative Recovery
- Trial name
- PRE-QoR (NCT07879209)
- Testing
- Handgrip Strength (HGS) Measurement, Ultrasound Shear Wave Elastography (SWE)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Osteoarthritis, Hip, Arthritis
Longterm-Evaluation of Vitelene® Against Standard
The purpose of this randomised prospective multicenter longterm study is to evaluate the survival rate of the implant, wear and periprosthetic osteolysis of highly cross-linked polyethylene with and without addition of Vitamin E…
- Trial name
- VITAS (NCT01713062)
- Testing
- Vitelene, XLPE
- Where
- 6 sites in Germany
- Volunteers
- 400 people
- Sponsor
- Aesculap AG
Intertrochanteric Femur Fracture, Hip Fracture Surgeries
Inflammatory Indices, Early Mortality, and ICU Stay in Geriatric PFN Patients
This retrospective observational cohort study aims to evaluate the association between preoperative and postoperative inflammatory indices and early postoperative outcomes in geriatric patients undergoing proximal femoral nailing…
- Conditions
- Intertrochanteric Femur Fracture, Hip Fracture Surgeries, Geriatric Anesthesia
- Trial name
- PFN-RAR (NCT07607886)
- Where
- Turkey (Türkiye)
- Volunteers
- 233 people
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Cognitive Dysfunction, Alzheimer Disease
Tau Pathology in the Brain After Hip or Knee Replacement Surgery
The goal of this observational study is to study whether major surgery is linked to changes in the brain that are typical of Alzheimer's disease.
- Conditions
- Postoperative Cognitive Dysfunction, Alzheimer Disease, Tauopathies, Neuroinflammation
- Trial name
- TAU-PET (NCT07871487)
- Testing
- Hip or Knee Arthroplasty Under Spinal Anesthesia
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University Hospital
Fall Injury, Hip Fractures
Fall, Fracture and Frailty
This project aims to improve the global outcome for an aging individual after a traumatic fall, through identifying conditions contributing to a fall and promoting recovery and rehabilitation.
- Conditions
- Fall Injury, Hip Fractures, Risk Reduction, Osteoporosis, Osteopenia
- Trial name
- FFF (NCT05712252)
- Where
- Sweden
- Volunteers
- 1,200 people
- Sponsor
- Region Skane
Cerebral Palsy, Hip Surgery Corrective
Tranexamic Acid to Reduce Blood Loss After Varus Derotation Osteotomy
TABLO (Tranexamic Acid to reduce Blood Loss after varus derotation Osteotomy) is a clinical trial of postoperative tranexamic acid vs placebo in non-ambulatory children with cerebral palsy (CP) undergoing reconstructive hip…
- Conditions
- Cerebral Palsy, Hip Surgery Corrective, Tranexamic Acid Use, Blood Loss, Surgical
- Trial name
- TABLO (NCT07672158)
- Testing
- Tranexamic Acid (IV)
- Where
- Australia
- Volunteers
- 52 people
- Sponsor
- Murdoch Childrens Research Institute
Hip Fractures, In-hospital Mortality
Mortality and Predictors of In-hospital Mortality Among Geriatric Patients With Hip Fracture
To assess the incidence of in-hospital mortality among geriatric patients with hip fractures and to identify its potential predictors
- Trial name
- NCT07873918
- Volunteers
- 141 people
- Sponsor
- Assiut University
Atypical Femur Fracture
Quebec Registry for Atypical Femur Fractures
Bisphosphonates are recommended as first-line agents to reduce fracture risk in patients with osteoporosis and have in general an excellent safety profile.
- Trial name
- NCT02150850
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- McGill University
Arthrosis, Traumatic Arthritis
The Medacta International SMS Post-Marketing Surveillance Study
This is a Post-Marketing Surveillance of SMS femoral stem prosthesis.
- Conditions
- Arthrosis, Traumatic Arthritis, Rheumatoid Polyarthritis, Congenital Hip Dysplasia
- Trial name
- NCT02748408
- Testing
- SMS femoral stem
- Where
- 4 sites in Austria, Italy and 2 more
- Volunteers
- 550 people
- Sponsor
- Medacta International SA
Hip Arthritis, Hip Disease
MDR - PMCF Study for Taperloc Complete Stems
The objective of this consecutive series PMCF study is to collect data confirming safety, performance, and clinical benefits of the Taperloc Complete stems when used for primary or revision total hip arthroplasty (implants) at…
- Conditions
- Hip Arthritis, Hip Disease, Hip Fractures, Hip Injuries
- Trial name
- NCT04028687
- Testing
- Taperloc Complete Stem
- Where
- 3 sites in United States
- Volunteers
- 820 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Hip, Avascular Necrosis of Hip
Avenir Complete Post-Market Clinical Follow-Up Study
The main objectives of this study are to confirm the long-term safety, performance and clinical benefits the Avenir Complete femoral stem and its instrumentation when used in primary total, hemi, and revision hip arthroplasty.
- Conditions
- Osteoarthritis, Hip, Avascular Necrosis of Hip, Avascular Necrosis of the Femoral Head, Post-traumatic; Arthrosis
- Trial name
- NCT04731077
- Testing
- Avenir Complete Femoral Stem
- Where
- 9 sites in United States, Denmark and 4 more
- Volunteers
- 275 people
- Sponsor
- Zimmer Biomet