Clinical trials: Hip Infection
Prosthetic-joint Infection
The Effect of Peri-Operative Adjunctive Probiotics on Immunological Markers in Cases of Prosthetic Joint Infection of the Hip and Knee
The purpose of this study is to determine whether probiotics in addition to standard of care (SOC) can improve immunological markers following treatment for prosthetic joint infection (PJI).
- Trial name
- NCT06919913
- Testing
- Culturelle Digestive Daily Probiotic Capsule
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- NYU Langone Health
Low Back Pain
Effects of Magnetic Tape Over Hip Cutaneous Nerves in Patients With Low Back Pain
A tape is applied over the inguinal skin nerves in people with low back pain. When placing the experimental tape, mobility should be improved and when the area is cooled with the tape, rotation should be limited again by…
- Trial name
- NCT04845477
- Testing
- Magnetic tape, Kinesiology tape
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Francisco Selva
Surgical Site Infection, Unplanned Fracture-Related Reoperation
Pre-operative Alcohol Skin Solutions in Fractured Extremities
The prevention of infection is an important goal influencing peri-operative care of extremity fracture patients. Standard practice in the operative management of extremity fractures includes sterile technique and pre-operative…
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture, Closed Lower Extremity Fracture
- Trial name
- PREPARE (NCT03523962)
- Testing
- DuraPrep, ChloraPrep
- Where
- 27 sites in United States, Canada
- Volunteers
- 8,485 people
- Sponsor
- University of Maryland, Baltimore
Hip Fractures, Covid19
COVID-19 Pandemic on Health Care and Rehabilitation Outcomes
Fragility fracture is easily associated with a clinical worsening of patients in terms of quality of life and disability in the medium and long term.
- Trial name
- HIP COVID (NCT04882670)
- Where
- Italy
- Volunteers
- 360 people
- Sponsor
- Istituto Ortopedico Rizzoli
SARS-CoV2 Infection, Hip Fractures
Hip Fracture and COVID-19
Hip fracture in the elderly is a worldwide public health issue and a medical challenge for early postoperative rehabilitation. More than 2 million people are treated annually with an annual incidence between 100 and 300/100,000…
- Conditions
- SARS-CoV2 Infection, Hip Fractures, Surgery
- Trial name
- COLCOVID (NCT04944329)
- Testing
- Hip fracture surgery
- Where
- France
- Volunteers
- 73,661 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Osteoarticular Infection
Efficacy of Dalbavancin in Osteoarticular Infections Associated With Hip and Knee Replacements
Osteoarticular infections associated with hip and knee prostheses require optimal surgical and medical management to maximize the rate of therapeutic success. Antibiotic therapy should be administered for a period of 12 weeks.
- Trial name
- PRODALBA (NCT05046860)
- Testing
- Dalbavancin
- Where
- 4 sites in France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Sepsis, Osteoporotic Hip Fracture
Prediction of Mortality and Morbidity After Hip Fracture Using Monocyte Distribution Width (MDW)
Hip fracture is a common injury in older adults and is often associated with serious complications, longer hospital stays, and increased risk of death.
- Conditions
- Sepsis, Osteoporotic Hip Fracture, Hip Fracture
- Trial name
- MDW (NCT07350785)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- National and Kapodistrian University of Athens
Infection Prosthesis Hip and Knee, Infection, Prosthesis Related
Results of Extended Versus Single Dose Antibiotic Prophylaxis In Orthopedic Revision Arthroplasty in Nijmegen.
The goal of this randomized control trial is to investigate the superiority of 5 days (extended) versus a single dose of cefazolin prophylaxis in revision arthroplasty of the hip and knee.
- Conditions
- Infection Prosthesis Hip and Knee, Infection, Prosthesis Related, Joint Infection, Infection, Surgical Site
- Trial name
- REViSION (NCT06402591)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 751 people
- Sponsor
- Radboud University Medical Center
Urinary Tract Infections
A Trial of Different Methods for Bladder Drainage in Hip Surgery Patients
The aim of the project is to evaluate differences between intermittent and indwelling catheterisation in patients with hip surgery.
- Trial name
- NCT01333254
- Testing
- Intermittent urinary catheterisation
- Where
- Sweden
- Volunteers
- 170 people
- Sponsor
- Region Örebro County
Hip Fractures, Pneumonia
The Effect of Zoledronate on the Prevention of Pneumonia in Hip Fracture Patients
Nitrogen-containing bisphosphonates (N-BPs; such as alendronate and zoledronate) are commonly used in the treatment of osteoporosis and fracture prevention, in which zoledronate has a proven better efficacy than alendronate.
- Trial name
- Zoo-P (NCT05743179)
- Testing
- Zoledronate
- Where
- 5 sites in Hong Kong
- Volunteers
- 2,692 people
- Sponsor
- The University of Hong Kong
Prosthetic Joint Infection
Tissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee Arthroplasty
This study will investigate TNP-2092 distribution into joint tissues in participants undergoing a total hip arthroplasty (THA) or a total knee arthroplasty (TKA).
- Trial name
- NCT04294862
- Testing
- TNP-2092
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- TenNor Therapeutics Limited
Coxarthrosis
Effects of the Sangvia Blood Collection System on Postoperative Infections in Orthopedic Patients
The purpose of this study is to compare the infection rate in patients receiving/not receiving their own blood, collected during surgery, during and after orthopedic surgery.
- Trial name
- NCT01725724
- Testing
- Autologous blood transfusion, Allogeneic blood transfusion
- Where
- 4 sites in Norway
- Volunteers
- 162 people
- Sponsor
- Haukeland University Hospital
Adverse Reactions to Metal Debris, Infection of Total Hip Joint Prosthesis
Imaging of Joint Replacement Complications by PET/CT
Total hip replacement is the well-established surgical method for treatment of hip osteoarthritis and related diseases. The outcome of the procedure is commonly satisfactory and most patients will not need any revision surgery.
- Conditions
- Adverse Reactions to Metal Debris, Infection of Total Hip Joint Prosthesis, Mechanical Loosening of Prosthetic Joint
- Trial name
- Propeli (NCT01970228)
- Testing
- 68Ga-citrate and 18F-FDG PET/CT imaging
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Turku University Hospital
Bone Diseases, Infectious
Drug Penetration Into Bone After Repeated Oral Administration of Debio 1450 to Patients Undergoing Hip Replacement Surgery
Debio 1450 is being developed for the treatment of staph (staphylococcal) infections. How fast and completely an antibiotic penetrates into bone is used to determine how effective it might be to treat infections related to bones…
- Trial name
- NCT02726438
- Testing
- Debio 1450
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Debiopharm International SA
Hip Arthroplasty
Influence of Sevoflurane and Desflurane on Postoperative Sore Throat
This investigation is planned to compare the incidence and severity of postoperative sore throat according to the use of sevoflurane or desflurane.
- Trial name
- NCT03259672
- Testing
- Sevoflurane, Desflurane
- Volunteers
- 100 people
- Sponsor
- Keimyung University Dongsan Medical Center
Hip Prosthesis Infection
Single-stage Surgery With Antibiotic-loaded Hydrogel Coated Implants Versus Two Stage Surgery for Secondary Prevention of Complex Chronic Periprosthetic Hip Joint Infection
Each year, around 1500 infected Total Hip Arthroplasties (THA) need non-conservative surgery, remaining an issue for patients and healthcare units.
- Trial name
- SINBIOSE-H (NCT04251377)
- Testing
- Defensive Antiadhesive Coating DAC®, Novagenit SRL
- Where
- 14 sites in France
- Volunteers
- 39 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Femoral Neck Fractures, SARS-CoV 2
A Study of Outcomes in Patients With Fractured Neck of Femur During the COVID-19 Pandemic
In early 2020 the evolving COVID-19 Pandemic provided the world and medical community with a generational challenge. As a novel disease, countries were left with strategic decisions and many went into social lockdown.
- Trial name
- NCT04375501
- Testing
- Surgery: Dynamic Hip Screw, hemiarthroplasty, hip replacement, intramedullary nail
- Where
- United Kingdom
- Volunteers
- 442 people
- Sponsor
- Barts & The London NHS Trust
Fracture of Hip, Total Hip Arthroplasty
Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With a Fracture
Aim: To compare the effect of one single dose versus multiple doses of prophylactic antibiotics administered within 24 hours, on the development of PJI after surgery in patients undergoing primary THA due to an acute fracture or…
- Conditions
- Fracture of Hip, Total Hip Arthroplasty, Prosthetic-joint Infection, Fracture Acetabular
- Trial name
- ProHipQ-F (NCT05530174)
- Testing
- Antibiotic dosage practice
- Where
- 36 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Soren Overgaard
Infection of Total Hip Joint Prosthesis
Evaluating Advantages of Prevena After Hip and Knee Arthroplasty
Determine the extent to which application of the Prevena vacuum system to clean surgical incisions immediately following surgical procedure (total hip or total knee arthroplasty) will reduce the rates of: readmission to hospital…
- Trial name
- NCT01854138
- Testing
- Prevena Incision Management System
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- ProMedica Health System
Hip Arthroplasty
Influence of Remifentanil on Postoperative Sore Throat in Patients Undergoing General Anesthesia
This investigation is planned to compare the incidence and severity of postoperative sore throat according to the dose of remifentanil.
- Trial name
- NCT03173339
- Testing
- Endotracheal intubation using laryngoscope, High remifentanil, Low remifentanil
- Where
- South Korea
- Volunteers
- 92 people
- Sponsor
- Keimyung University Dongsan Medical Center