Clinical trials: Hip Infection
Delirium, Confusion
Improving Safety of Diagnosis and Therapy in the Inpatient Setting
To improve the safety of diagnosis and therapy for a set of conditions and undifferentiated symptoms for hospitalized patients, the investigators will employ a set of methods and tools from the disciplines of systems engineering…
- Conditions
- Delirium, Confusion, Mental Status Change, Back Pain
- Trial name
- PSLL2-0 (NCT04393909)
- Testing
- Diagnostic Uncertainty Educational Curriculum, Diagnostic Timeout, Patient Diagnostic (Dx) Questionnaire
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Brigham and Women's Hospital
Fracture, Infection
A Geriatric Home Visit Program to Reduce Post-Hip Fracture Complications
The overall goal of the project is to reduce the incidence of post hip fracture morbidity and mortality by conducting geriatric fellow periodic home visits.The assessment will be multidisciplinary and will include assessments of…
- Conditions
- Fracture, Infection, Depression, Gait Instability
- Trial name
- NCT02058329
- Testing
- Home Visit
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Northwell Health
Prosthetic Joint Infection
68Ga-citrate PET/CT for the Diagnosis of Chronic Prosthetic Hip or Knee Infection
Diagnosis of chronic prosthetic joint infection (PJI) can be difficult. 68Ga-citrate Positron Emission Tomography/Computed Tomography (PET/CT) has been recently developed and has many advantages such as high resolution and low…
- Trial name
- Gal-I-TEP (NCT04938193)
- Testing
- 68Ga-citrate PET/CT
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Bordeaux
Surgical Wound Infection
Bacterial Colonization With and Without Iodophor-impregnated Adhesive Drapes in Hip Surgery: a Prospective, Randomized Trial
This is a prospective, randomized control trial evaluating the efficacy of iodophor-impregnated adhesive drapes for reducing bacterial count in hip surgery.
- Trial name
- NCT02919410
- Testing
- iodophor-impregnated adhesive drapes, No adhesive drapes
- Sponsor
- Rothman Institute Orthopaedics
Septic Arthritis
Short Term Results of Pediatric Septic Hip Arthritis Management in Assiut University Hospitals
Detect short term results of pediatric septic hip arthritis and its risk factors
- Trial name
- NCT05780697
- Testing
- Surgery of Drainage of septic hip arthritis
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infection, Debridement With Prosthesis Retention
Treatment Results on Patients With Debridement and Prosthesis Retention in the Hip
This study presents the investigators results on patients treated for infection in the implemented hip prosthesis. Debridement and prosthesis retention is the method, followed by antibiotic treatment.
- Trial name
- NCT00757445
- Where
- Norway
- Volunteers
- 105 people
- Sponsor
- Sorlandet Hospital HF
Prosthetic Joint Infections of Hip, Bacteriophage Therapy
Bacteriophage Therapy for Staphylococcus Lugdunensis Prosthetic Joint Infection
This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Staphylococcus lugdunensis prosthetic joint infection of the hip.
- Trial name
- NCT07461337
- Testing
- Five phage anti-Staphylococcus aureus bacteriophage cocktail
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Calgary
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Patient Oriented Discharge Summary Impact Study
Improving the patient experience has become a major focus of quality improvement efforts in Ontario and in health systems worldwide.
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Pneumonia, Hip Fracture
- Trial name
- PODS (NCT02673892)
- Testing
- Patient Oriented Discharge Summary
- Where
- Canada
- Volunteers
- 581 people
- Sponsor
- University Health Network, Toronto
Prosthetic Joint Infection
Study to Evaluate Safety and Activity of TRL1068 in Prosthetic Joint Infections
TRL1068 is expected to eliminate the pathogen-protecting biofilm in the prosthetic joint and surrounding tissue, thus making these pathogens substantially more susceptible to established antibiotic treatment regimens.
- Trial name
- NCT04763759
- Testing
- TRL1068, a human monoclonal antibody
- Where
- 9 sites in United States
- Volunteers
- 15 people
- Sponsor
- Trellis Bioscience LLC
Prosthetic Joint Infections
[124I]FIAU PET-CT Scanning in Patients With Pain in a Prosthetic Knee or Hip Joint
This protocol will evaluate the sensitivity and specificity of [124I]FIAU as a diagnostic imaging agent for the detection of prosthetic joint infections in patients.
- Trial name
- PJI (NCT01705496)
- Testing
- [124I]FIAU
- Where
- 10 sites in United States
- Volunteers
- 23 people
- Sponsor
- BioMed Valley Discoveries, Inc
HIV Infections
HIP: HIV Intervention for Providers
The purpose is to encourage Provider participants to evaluate high risk HIV transmission behaviors and offer prevention messages to their HIV+ patients which will, in turn, reduce rates of unprotected anal and/or vaginal sex with…
- Trial name
- NCT00164398
- Testing
- HIP: HIV Intervention for Providers
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Femur Fracture, Periprosthetic Fracture of Hip
Dose-Response Association Between Cerclage Wire Number and Infection Risk
The purpose of this dual-center retrospective study is to investigate the relationship between the number of metallic cerclage wires used in femoral fracture surgery and the risk of developing deep infections.
- Conditions
- Femur Fracture, Periprosthetic Fracture of Hip, Periprosthetic Fracture of the Femur, Surgical Site Infection (SSI)
- Trial name
- C-INFECT (NCT07434258)
- Testing
- 1 Metallic Cerclage Wiring, 2 metalic cerclage wire, 3 metalic cerclage wire
- Volunteers
- 148 people
- Sponsor
- Istanbul University
Hip Prosthesis Infection
Contribution of a Clinical Pathway for the Treatment of Hip Prosthesis Infections
The main objective is to determine the contribution of a clinical pathway to improve the effectiveness of medico-surgical management of hip prosthesis infections in terms of clinical cure.
- Trial name
- OSCAR-PH (NCT02660268)
- Testing
- Clinical Pathway
- Where
- 7 sites in France
- Volunteers
- 164 people
- Sponsor
- University Hospital, Grenoble
Joint (Knee or Hip Replacement), Infection as Complication of Medical Care
Swiss Revision Cohort
This study follows patients with infections after a joint replacement over time. During follow-up, treatment outcomes are carefully measured to determine whether the infection can be cured.
- Trial name
- REVCO (NCT07473089)
- Testing
- Revision for periprosthetic joint infections of the hip, knee, shoulder, elbow or ankle
- Where
- 5 sites in Switzerland
- Volunteers
- 329 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Bone Loss, Hip Prosthesis Infection
Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)
In this prospective multicenter study, a population of adult individuals consecutively treated for revision hips, requiring a custom-made acetabular implant for non-oncological reasons, will be included.
- Conditions
- Bone Loss, Hip Prosthesis Infection, Arthroplasty Complications
- Trial name
- CustomPN (NCT06527664)
- Testing
- custom-made acetabular implant
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection
To determine if oral antibiotic treatment with CEM-102 and Rifampin is as effective and safe as the standard of care antibiotic therapy for the treatment of hip and knee prosthetic joint or spacer infections
- Conditions
- Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Infected Spacers
- Trial name
- NCT01756924
- Testing
- CEM-102, IV or Oral standard of care antibiotics, Rifampin
- Where
- 13 sites in United States
- Volunteers
- 14 people
- Sponsor
- Arrevus Inc.
Wound Healing Time, Total Hip Arthroplasty (THA)
Wound Healing, Dressing Type, and Dressing Change Frequency in THA
Surgical wound complications following primary total hip arthroplasty remain a significant clinical challenge despite advances in wound care technologies.
- Trial name
- CAP-HIP (NCT07655388)
- Testing
- VACUTEX™ wound dressing, Octenisept® wound care dressing
- Where
- Serbia
- Volunteers
- 90 people
- Sponsor
- Clinical Center of Vojvodina
Sonication, Total Hip Replacement
Biofilm Investigation on Bearing Components of Explanted Hip Joint Prosthesis
In this study the investigators sonicate the bearing components of the explanted hip prosthesis which allows highly sensitive detection of in vivo biofilms (qualitatively and quantitatively).
- Conditions
- Sonication, Total Hip Replacement, Biofilm
- Trial name
- NCT02853461
- Testing
- Sonication, Microbiological analysis
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Charite University, Berlin, Germany
Prosthetic-joint Infection, Dysbiosis
Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee
Prosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty (TJA) of the hip and knee. Standard of care (SOC) treatment includes surgery and antimicrobials.
- Trial name
- NCT06636669
- Testing
- Probiotic, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- Boston Medical Center
Hip Fractures, Hypotension on Induction
Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study.
Background During anaesthesia for repair of a broken hip, many patients experience low blood pressure. There have been many studies showing that patients who experience low blood pressure during anaesthesia are at increased risk…
- Conditions
- Hip Fractures, Hypotension on Induction, Intraoperative Hypotension, Acute Kidney Injury
- Trial name
- iSTABILISE (NCT04051073)
- Testing
- Continuous non-invasive blood pressure monitoring
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust