Clinical trials: Hip Joint Disorders
Hip Osteoarthritis
A Prospective Multi-center Study on Total Hip Arthroplasty With E1
The primary objectives of this clinical study include: Evaluate E1 Wear including early bedding-in process, clinical outcomes on patients who received Total Hip Arthroplasty with E1 Compare E1 wear used with CoCr and Biolox Delta…
- Trial name
- NCT01883492
- Testing
- Femoral Stem, Acetabular Cup, Acetabular Liner
- Where
- 5 sites in Japan
- Volunteers
- 153 people
- Sponsor
- Zimmer Biomet
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Osteoarthritis
A Five-Year Metal-on-Metal Retrospective Clinical Study
This retrospective study will review the Anderson Orthopaedic Institute's initial experience among a consecutive series of 126 patients who had primary total hip arthroplasty using a metal-on-metal articulation consisting of a…
- Trial name
- NCT01481896
- Testing
- Metal-on-metal primary total hip arthroplasty (DePuy )
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Anderson Orthopaedic Research Institute
Knee Osteoarthritis, Hip Osteoarthritis
Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties
Barbed sutures offer several potential advantages in layered wound closure of hip and knee replacement surgeries. It use is gaining increased acceptance across many of the other surgical disciplines at this time.
- Trial name
- NCT00834483
- Testing
- Knotless suture for wound closure, Layered traditional wound closure (monocryl)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoarthritis of the Hip
The MONOVISC Hip Osteoarthritis Study
This study is being done to determine the effectiveness of MONOVISC for the relief of pain and symptoms of osteoarthritis of the hip.
- Trial name
- NCT02698865
- Testing
- MONOVISC, Saline
- Where
- 27 sites in United States
- Volunteers
- 220 people
- Sponsor
- DePuy Mitek
Chronic Low-back Pain, Hip Impairments
Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Older adults with chronic low back pain (LBP) are at a greater risk for disability, loss of independence, and lower quality of life.
- Conditions
- Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
- Trial name
- MASH (NCT04009837)
- Testing
- Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Delaware
Hip Osteoarthritis, Knee Osteoarthritis
Comparative Effectiveness of Decision Support Strategies for Joint Replacement Surgery
This study is a 2X2 factorial randomized trial that will the examine the comparative effectiveness of two patient decision aids for hip and knee osteoarthritis (OA) as well as the impact of a surgeon-focused intervention.
- Trial name
- NCT02729831
- Testing
- Interactive decision aid, Video decision aid, Provider Report
- Where
- 3 sites in United States
- Volunteers
- 1,220 people
- Sponsor
- Massachusetts General Hospital
Hip Osteoarthritis
Platelet Rich Plasma vs Hyaluronic-Acid in Hip OA (Osteoarthritis)
The objective of this study is to compare the clinical efficacy of intra-articular injections of autologous platelet rich plasma (PRP) vs hyaluronic acid (HA) for symptomatic early osteoarthritis (OA) of the hip.
- Trial name
- NCT01920152
- Testing
- PRP, Hyaluronic Acid
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Colorado, Denver
Total Hip Arthroplasty, Osteoarthritis
Improving Rehabilitation Outcomes After Total Hip Arthroplasty
This study plans to learn more about the effects of physical therapy (PT) following a total hip arthroplasty (THA). The purpose of this study is to compare standard of care PT after THA with a physical therapy program…
- Trial name
- NCT02920866
- Testing
- Functional Strength Integration (FSI), Control Group (CON)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- VA Office of Research and Development
Insomnia, Pain
Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery.
- Conditions
- Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- HH (NCT04269239)
- Testing
- Healthy Habits, Sleep Habits
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- Baylor College of Medicine
Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA)
Study to Evaluate the Safety and Efficacy of OR3O™ Dual Mobility System vs. Conventional Single Bearing Design Total Hip System
The purpose of this study is to compare OR3O™ Dual Mobility System to a conventional, single-bearing design Total Hip System in subjects who undergo Primary THA.
- Conditions
- Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA), Femoral Neck Fractures, Avascular Necrosis of Femoral Head
- Trial name
- OR3O (NCT04941729)
- Testing
- OR3O™ - Dual Mobility System, Conventional
- Where
- 4 sites in China
- Volunteers
- 24 people
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
Osteoarthritis, Hip, Osteoarthritis, Knee
Study of the Analgesic Efficacy and Safety of Subcutaneous Tanezumab in Subjects With Osteoarthritis of the Hip or Knee.
Tanezumab is a monoclonal antibody that binds to and inhibits the actions of nerve growth factor (NGF). The Nerve Growth Factor Inhibitor (NGFI) class may offer an important breakthrough in the treatment of chronic pain and is…
- Trial name
- NCT02709486
- Testing
- Tanezumab
- Where
- 148 sites in Austria, Bulgaria and 13 more
- Volunteers
- 849 people
- Sponsor
- Pfizer
Arthropathy of Hip
Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
The goal of this retrospective chart review is to evaluate if the implementation of lumbar plexus block placement for postoperative pain have improved conditions in the postoperative period for patients undergoing total hip…
- Trial name
- NCT02493621
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Osteoarthritis
Open-Label Study of Diclofenac Capsules to Treat Osteoarthritis Pain
The purpose of this study is to evaluate the safety of Diclofenac [Test] Capsules for the treatment of osteoarthritis pain of the knee or hip.
- Trial name
- NCT01510912
- Testing
- Diclofenac
- Where
- 40 sites in United States
- Volunteers
- 602 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Arthritis
Aquatic Exercise and Efficacy Enhancement to Decrease Fall Risk in Older Adults With Hip Osteoarthritis
The objective of this project is to determine the effect of aquatic exercise and aquatic exercise combined with an education program on decreasing fall risk in older adults with hip osteoarthritis.
- Trial name
- NCT00289458
- Testing
- exercise, 2, Control
- Where
- Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Arthropathy of Hip, Arthropathy of Knee
Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash
Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block.
- Trial name
- NCT02619409
- Testing
- Bupivacaine Only, EPI25, EPI50 group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Osteoarthritis
Study of Meloxicam Capsules to Treat Osteoarthritis Pain
The purpose of this study is to determine whether Meloxicam [Test] Capsules are safe and effective for the treatment of osteoarthritis pain of the knee or hip.
- Trial name
- NCT01787188
- Testing
- Meloxicam Test Capsules
- Where
- 40 sites in United States
- Volunteers
- 403 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain
The purpose of this study is to evaluate the safety profile of tapentadol (CG5503) PR at doses of 100 mg - 250 mg administered twice daily over a maximum one year period to patients with at least a 3-month history of low back…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Knee, Lower Back Pain, Pain
- Trial name
- NCT00361504
- Testing
- Oxycodone CR, Tapentadol (CG5503) ER
- Where
- 52 sites in United States, Canada
- Volunteers
- 1,123 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Femoroacetabular Impingement Syndrome, Acetabular Labral Tear
Postoperative Hip Bracing After Hip Arthroscopy
Hip arthroscopy for treatment of femoroacetabular impingement syndrome (FAIS) involves reshaping of the osseous sources of impingement ("osteoplasty") and treatment of impingement-associated labral tears with labral repair.
- Trial name
- NCT04599296
- Testing
- Hip brace
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Washington
Muscular Atrophy
A Study of LY2495655 in Older Participants Undergoing Elective Total Hip Replacement
The primary objective of this study is to test the hypothesis that appendicular lean body mass (aLBM) will increase after 12 weeks of LY2495655 treatment versus placebo in older participants undergoing elective total hip…
- Trial name
- NCT01369511
- Testing
- LY2495655
- Where
- 45 sites in United States, Austria and 9 more
- Volunteers
- 400 people
- Sponsor
- Eli Lilly and Company