Clinical trials: Hip Osteoarthritis
Osteoarthritis
Efficacy of Intravenous Versus Topical Tranexamic Acid in Primary Total Hip Arthroplasty
Bleeding during and after total hip replacement surgery is a primary concern to the surgical and anaesthetic team. Tranexamic acid is a commonly-used drug that helps blood clotting and decreases surgical bleeding.
- Trial name
- TeACH-R (NCT02056444)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Orthopedic, Osteo Arthritis Knee
Energy Status and Protein Intake As Prognostic Indicators of Rehabilitative Outcomes
The proposed project is novel in its goal to establish a foundation for evidence-based rehabilitative nutrition guidelines to enhance perioperative patient care and improve post-operative rehabilitative outcomes specific to…
- Conditions
- Orthopedic, Osteo Arthritis Knee, Hip Osteoarthritis, Protein-Energy Malnutrition
- Trial name
- ESPI-PRO (NCT06734845)
- Testing
- Total Knee Arthroplasty, Total Joint Arthroplasty
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Unilateral Primary Osteoarthritis of Hip
Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
The aim of this study is to investigate the clinical outcome of the two different, but widely used, surgical approaches (Posterior approach and Lateral approach) of primary total hip arthroplasty in patients diagnosed with…
- Trial name
- COMPALA (NCT01616667)
- Testing
- Total hip arthroplasty
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Osteoarthritis, Hip Osteoarthritis
Wharton's Jelly-derived Mesenchymal Stem Cells in Osteoarthritis
This phase I/II study will enroll 100 subjects with mild to moderate osteoarthritis of the hip/knee/ glenohumeral joint will be enrolled according to strict inclusion and exclusion criteria.
- Conditions
- Osteoarthritis, Hip Osteoarthritis, Knee Osteoarthritis, Glenohumeral Osteoarthritis
- Trial name
- NCT03866330
- Testing
- Intraarticular injection of WJMSC
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Osteoarthritis, Hip
Unrestricted Rehabilitation Following Primary THA
The purpose of this study is to determine whether the form of rehabilitation following primary total hip arthroplasty has an influence on patient satisfaction or functional performance in the eighteen weeks following surgery.
- Trial name
- NCT02079467
- Testing
- Unrestricted rehabilitation, Standard rehabilitation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Osteoarthritis of Hip
Investigation to Determine Safety of Taperloc Stems With BioGuard Coating When Used in Cementless Total Hip Arthroplasty
Prospective clinical investigation to determine the safety of Taperloc stems with BioGuard coating and Exceed ABT Taperfit acetabular cups with BioGuard coating when used in cementless total hip arthroplasty
- Trial name
- NCT02263209
- Testing
- Bioguard Group, Control Group
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Hip Osteoarthritis, Hip Pain Chronic
Dexamethasone With Ropivacaine for PENG Block in Total Hip Arthroplasty
Does adding Dexamethasone to the Periarticular Nerve Group Block in Patients undergoing Total Hip Arthroplasty reduce the dose of ropivacaine?
- Conditions
- Hip Osteoarthritis, Hip Pain Chronic, Hip Arthritis
- Trial name
- NCT06470334
- Testing
- Ropivacaine, Ropivacaine+Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Hip Osteoarthritis
Platelet Rich Plasma vs Hyaluronic-Acid in Hip OA (Osteoarthritis)
The objective of this study is to compare the clinical efficacy of intra-articular injections of autologous platelet rich plasma (PRP) vs hyaluronic acid (HA) for symptomatic early osteoarthritis (OA) of the hip.
- Trial name
- NCT01920152
- Testing
- PRP, Hyaluronic Acid
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Colorado, Denver
Hip Osteoarthritis, Arthropathy of Hip
PENG Block vs PENG Plus Periarticular Injection vs Periarticular Injection in Older Adults
Pain after hip surgery is common in older adults and may limit early mobilization, increase the need for opioid medications, and contribute to complications such as delirium, nausea, or prolonged hospital stay.
- Trial name
- NCT07327892
- Testing
- Pericapsular Nerve Group (PENG) Block, Periarticular Injection (PAI)
- Where
- Poland
- Volunteers
- 108 people
- Sponsor
- Poznan University of Medical Sciences
Osteoarthritis
A Randomized Controlled Trial of Long Versus Short Wait For Primary Total Hip and Knee Arthroplasty
The primary research question is: Does expedited hip and knee replacement result in improved lower-extremity function at 36 months post randomization as measured by the Western Ontario McMaster Universities Osteoarthritis Index…
- Trial name
- NCT00138892
- Testing
- Waiting time (access time to Total joint replacement)
- Where
- Canada
- Volunteers
- 236 people
- Sponsor
- University of British Columbia
Hip Osteoarthritis, Hip Arthropathy
Dexamethasone for PENG Block in Total Hip Arthroplasty
Effect of adding Dexamethasone to Periarticular Nerve Group Block in Patients undergoing Total Hip Arthroplasty
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Pain Chronic
- Trial name
- NCT06470139
- Testing
- Ropivacaine 0.2% Injectable Solution, Ropivacaine 0.2% Injectable Solution + 4mg Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Total Hip Arthroplasty, Osteoarthritis
Improving Rehabilitation Outcomes After Total Hip Arthroplasty
This study plans to learn more about the effects of physical therapy (PT) following a total hip arthroplasty (THA). The purpose of this study is to compare standard of care PT after THA with a physical therapy program…
- Trial name
- NCT02920866
- Testing
- Functional Strength Integration (FSI), Control Group (CON)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- VA Office of Research and Development
Osteoarthritis, Hip, Hip Disease
Multicenter Study for Robotic Arm-assisted THA 4.0 System: Hip Spine Relationship
The current study is a multi-center study to assess precision and accuracy of the robotic system with new software.
- Trial name
- NCT04646096
- Testing
- MAKO THA 4.0 System
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- American Hip Institute
Dislocation, Hip
Dual Mobility Cup Versus Unipolar Cup
The general purpose of this study is to examine whether the dual mobility cup (Novae® Serf) reduces the number of hip dislocations after total hip replacement, both early dislocation (≤1 year) and late dislocation (>1 year) after…
- Trial name
- NCT04685239
- Testing
- dual mobility cup, unipolar cup
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Insomnia, Pain
Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
This study aims to evaluate behavioral interventions in conjunction with medical rehabilitation to promote functional health in patients recovering from orthopedic surgery.
- Conditions
- Insomnia, Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- HH (NCT04269239)
- Testing
- Healthy Habits, Sleep Habits
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- Baylor College of Medicine
Hip Osteoarthritis
Effectiveness of Total Hip Arthroplasty for Patients With Osteoarthritis, a Target Trial Emulation Study
The aim of this study is to assess the effect of total hip arthroplasty on hip disability and pain compared to non-surgery in patients with hip osteoarthritis, using target trial emulation to emulate a randomized controlled trial.
- Trial name
- EAGLE (NCT06263569)
- Testing
- Total hip arthroplasty
- Where
- Netherlands
- Volunteers
- 156 people
- Sponsor
- JointResearch
Hip Dysplasia, Hip Pain Chronic
Psychosocial Interventions for Young Adults With Hip Pain
Psychosocial conditions are common in young adults with hip pain including depression, anxiety, pain catastrophizing, and narcotic use. The incidence of these conditions is not well defined.
- Conditions
- Hip Dysplasia, Hip Pain Chronic, Hip Osteoarthritis, Hip Arthritis
- Trial name
- NCT04039386
- Testing
- Cell Phone Based Cognitive Based Therapy (Pacifica App), Control
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Michael C Willey
Total Hip Arthroplasty, Computer-Assisted Surgery
Pre-Op THA Modelling
Replacing diseased hip joints with prosthetic implants in a procedure called total hip arthroplasty (THA) is associated with high rates of patient satisfaction, pain relief, and functional improvement when the implant is…
- Trial name
- NCT05221554
- Testing
- Imageless computer-navigated THA surgery, Standard of care THA surgery, CT-based Computer-navigated THA surgery
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis, Hip
Early Rehabilitation After Total Hip Replacement
The purpose of this study is to determine whether supervised progressive resistance training is effective in the early phase after Total Hip Replacement.
- Trial name
- NCT01214954
- Testing
- Supervised progressive resistance training, Control group
- Where
- Denmark
- Volunteers
- 73 people
- Sponsor
- University of Aarhus
Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA)
Study to Evaluate the Safety and Efficacy of OR3O™ Dual Mobility System vs. Conventional Single Bearing Design Total Hip System
The purpose of this study is to compare OR3O™ Dual Mobility System to a conventional, single-bearing design Total Hip System in subjects who undergo Primary THA.
- Conditions
- Degenerative Hip Joint Disease, Rheumatoid Arthritis (RA), Femoral Neck Fractures, Avascular Necrosis of Femoral Head
- Trial name
- OR3O (NCT04941729)
- Testing
- OR3O™ - Dual Mobility System, Conventional
- Where
- 4 sites in China
- Volunteers
- 24 people
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
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