Clinical trials: Hip Replacement, open to volunteers
Arthroplasties, Hip Replacement
Comparison of Functional Results of ADM X3-MoP Cup (Stryker) and a CoC Cup (Zimmer) in Young Patients
A Single-Center Randomized, Patient-Blinded, Prospective Five-Year Study to Compare the Functional Results after Insertion of ADM X3-MoP Cup (Stryker) and a CoC Cup (Zimmer) in Primary THA.
- Trial name
- NCT02301182
- Testing
- ADM X3-MoP Cup, CoC Cup
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Joint (Knee or Hip Replacement)
The Impact of Extending Sleep Before Joint-replacement Surgery on Post-surgical Pain
This study will evaluate the impact of sleep banking on joint replacement surgery recovery.
- Trial name
- NCT07383584
- Testing
- Sleep banking
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Hip Osteoarthritis, Knee Osteoarthritis
The WHERE Study: Waiting for Hip and KneE REplacement
Total hip and knee replacements (TJR) for osteoarthritis are common orthopaedic procedures performed in Canada. Waits for these procedures are already common and lengthy, and the COVID-19 pandemic has resulted in the further of…
- Trial name
- WHERE (NCT06074900)
- Testing
- prospective cohort study
- Where
- Canada
- Volunteers
- 3,008 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Post Operative Pain, Acute, Sedation Score
Patient Control Epidural Versus Conventional Epidural.
As one of the complications of THR is post operative pain, which usually requires epidural catheter insertion. We are comparing the effect of patient control epidural versus conventional epidural for patient's satisfaction.
- Conditions
- Post Operative Pain, Acute, Sedation Score, Degree of Motor Block, Length of Hospital Stay
- Trial name
- NCT06721000
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Degenerative Joint Disease, Osteoarthritis, Hip
Safety and Effectiveness of the HIT Reverse HRS
The purpose of this study is to determine if the use of the HIT Reverse Hip Replacement System is safe and effective in patients undergoing total hip replacement.
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Hip, Avascular Necrosis of Hip, Traumatic Arthropathy-Hip
- Trial name
- NCT05357378
- Testing
- Hip Innovation Technology Reverse Hip Replacement System, Already-marketed semi-constrained uncemented hip systems using a metal-on-XLPE or ceramic-on-XLPE bearing combination.
- Where
- 6 sites in United States
- Volunteers
- 288 people
- Sponsor
- Hip Innovation Technology
Arthroplasty Complications, Muscle Weakness
Achilles Tendon for the Treatment of Gluteus Medius Insufficiency
Residual limping after total hip arthroplasty is a serious complication that lacks effective treatment. The purpose of this study is to evaluate a surgical treatment for residual limping and compare its results with non-surgical…
- Conditions
- Arthroplasty Complications, Muscle Weakness, Muscle Atrophy, Muscle Tear
- Trial name
- HLS (NCT05206838)
- Testing
- Surgical reconstruction of gluteus medius with Achilles tendon allograft
- Where
- Sweden
- Volunteers
- 44 people
- Sponsor
- Sahlgrenska University Hospital
Total Knee Arthroplasty
Biological Link Between Anxiety and Outcomes Post Knee Arthroplasty
This is a single-site, observational pilot study that aims to understand whether there is a biological explanation for why some patients with anxiety or depression experience poorer outcomes after total knee or hip replacement…
- Trial name
- NCT07102563
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Arthroplasty Complications
Are Elastic Restraints Still Necessary in Improved Rehabilitation Programs After Hip and Knee Prosthetic Surgery?
Venous thrombosis and pulmonary embolism are considered serious and potentially preventable complications of hip and knee replacement surgery.
- Trial name
- NCT06563531
- Testing
- Pharmacological thromboprophylaxis and elastic compression, Pharmacological thromboprophylaxis without elastic compression
- Where
- France
- Volunteers
- 1,274 people
- Sponsor
- Clinique Pasteur Lanroze
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
PENG Block
Efficacy of Dexmedetomidine As an Adjuvant to Bupivacaine in Pericapsular Nerve Group Block in Hip Replacement Surgeries
Our aim will be to investigate the efficacy of dexmedetomidine as an adjuvant to bupivacaine in ultrasound guided pericapsular nerve group (PENG) block for postoperative analgesia in hip replacement surgeries.
- Trial name
- NCT06736392
- Testing
- Ultrasound guided Pericapsular Nerve Group Block, Isobaric Bupivacaine 0. 25%, 20 ml isobaric bupivacaine 0.25% and 1.5μg/kg dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Surgical Wound
PICO 7 vs PICO 14 in Revision Hip and Revision Knee Surgery.
This is a single-site trial, and it has been designed to compare a revision hip cohort with a revision knee cohort. All consecutive eligible patients, under the care of participating Co-Investigator Orthopaedic Surgeons, are…
- Trial name
- NCT05389410
- Testing
- PICO 7, PICO 14
- Where
- United Kingdom
- Volunteers
- 164 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Surgical, Anxiety
Virtual Reality Therapy to Improve Arthroplasty Outcomes
Virtual reality (VR) has recently emerged as a non-medication-based method to manage anxiety. The patient wears a VR headset and is offered an immersive environment with hypnotic components with sound and imagery in a 3D…
- Conditions
- Surgical, Anxiety, Pain Management, Joint (Knee or Hip Replacement)
- Trial name
- VROOM (NCT07872670)
- Testing
- Virtual Reality Headset, Blood Samples, Questionnaires
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- NHS Highland Research, Development and Innovation Organisation
Knee Pain Chronic, Knee Pain Swelling
Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial
The goal of this clinical investigation is to evaluate the effectiveness on pain of arterial occlusion (embolization) of neovessels by microparticle in a double-blind sham controlled randomised trial in patients with persistent…
- Trial name
- EPROGE (NCT06466330)
- Testing
- microparticles, embolization
- Where
- 11 sites in France
- Volunteers
- 112 people
- Sponsor
- Societe Francaise de Rhumatologie
Perioperative Analgesia, Hip Replacement, Total
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty
The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach.
- Conditions
- Perioperative Analgesia, Hip Replacement, Total, Postoperative Pain, Hip Disease
- Trial name
- NCT07449585
- Testing
- PNEG block, Spinal anesthesia with opioid, Spinal anesthesia without opioid
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
Total Hip Replacement
Post-Market Observational Study of the HARMONY® Evolution Implants and Instruments
The purpose of this study is to evaluate the safety and performance of the HARMONY® Evolution implants in a series of operated subjects treated in THR.
- Trial name
- NCT06628336
- Testing
- HARMONY EVOLUTION
- Where
- 5 sites in France
- Volunteers
- 264 people
- Sponsor
- Symbios Orthopedie SA
Hip Disease
ACE Acetabular Cup Spanish PMCF Study
A total hip replacement is one of the most successful and cost-effective surgical procedures in orthopaedics, involving the replacement of both the hip ball and socket.
- Trial name
- NCT07115732
- Testing
- Total Hip Replacement
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- JRI Orthopaedics
Anesthesia for Hip Surgery
PENG Block vs ESPB in Elderly Undergoing Hip Surgeries
To our knowledge, the comparison between the ultrasound-guided lumbar erector spinae plane block and the pericapsular nerve group block has not been investigated before in previous literature.
- Trial name
- NCT06993376
- Testing
- PENG block, ESPB
- Volunteers
- 56 people
- Sponsor
- Cairo University
Virtual Reality, Hip Arthropathy
VR Effects After Hip Replacement Surgery Pain
Total Hip Arthroplasty (THA), a procedure performed to enhance the quality of life, is accompanied by postoperative challenges such as pain and anxiety that adversely affect patient comfort.
- Conditions
- Virtual Reality, Hip Arthropathy, Comfort, Anxiety
- Trial name
- THA (NCT07689461)
- Testing
- cognitive intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University
Hip Osteoarthritis, Knee Osteoarthritis
FitJoints: Getting Fit for Hip and Knee Replacement
Total hip or knee replacement is an important and cost-effective surgical intervention to relieve pain and improve independence and function in patients with osteoarthritis.
- Trial name
- NCT05100966
- Testing
- FitJoints Multi-modal Intervention
- Where
- 4 sites in Canada
- Volunteers
- 192 people
- Sponsor
- McMaster University
Fracture Femur, Hip Arthroplasty Replacement
Cognitive and Physical Recovery After Hip Fracture in Frail Patients Using Digital Rehabilitation Technology
The aim of this study is to evaluate whether integrating a technology-based rehabilitation approach with conventional therapies in the rehabilitation of patients with proximal femoral fracture may be advantageous compared with…
- Conditions
- Fracture Femur, Hip Arthroplasty Replacement, Total Hip Arthroplasty (THA)
- Trial name
- FEWF (NCT07392515)
- Testing
- Experimental intervention - integrated treatment with a sensor-based device, Conventional rehabilitation intervention
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- C.O.T. Cure Ortopediche Traumatologiche S.p.A.