Clinical trials: Hip Replacement Surgery, open to volunteers
Compassion
Electrocoagulation vs. Cold Knife Cutting in Joint Arthroplasty (Electrocoagulation vs Scalpel)
Comparison of clinical outcomes of electrocoagulation and non-electrocoagulation techniques in total hip and knee arthroplasty surgery
- Trial name
- evs (NCT06251869)
- Testing
- total hip arthroplasty with electrocoagulation, total hip arthroplasty without electrocoagulation, total knee arthroplasty with electrocoagulation
- Where
- Romania
- Volunteers
- 700 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Coxarthrosis
Comparison of Complication Rate, Functional Outcome and Quality of Life Between Standard Therapy Versus Fast-track Therapy in Patients Following Hip Replacement Surgery
The fast track group vs. control group will be compared with regard to hospitalization time and the non-inferiority of the fast track group vs. control group with regard to HOOS will be assessed.
- Trial name
- NCT07199751
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Technical University of Munich
Perioperative Neurocognitive Disorders
Mechanistic Study of PK2 Pathway in Alleviating Perioperative Neurocognitive Disorders by Improving Neurometabolic Uncoupling
The term perioperative neurocognitive disorders (PND) is derived from postoperative cognitive dysfunction (POCD), and has been renamed as PND in recent years in accordance with the latest international consensus.
- Trial name
- NCT07652008
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Virtual Reality, Hip Arthropathy
VR Effects After Hip Replacement Surgery Pain
Total Hip Arthroplasty (THA), a procedure performed to enhance the quality of life, is accompanied by postoperative challenges such as pain and anxiety that adversely affect patient comfort.
- Conditions
- Virtual Reality, Hip Arthropathy, Comfort, Anxiety
- Trial name
- THA (NCT07689461)
- Testing
- cognitive intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Adiyaman University
Osteoarthritis, Arthroplasty
Heidelberg Registry for Hip and Knee Joint Implants and Revisions
The Endoprosthesis Registry Heidelberg (EPR-HD) is a clinical registry designed to systematically collect and analyze data from patients undergoing primary implantation or revision surgery of artificial hip and knee joints.
- Trial name
- EPR-HD (NCT06850818)
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- University Hospital Heidelberg
Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis
Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty
This long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
- Conditions
- Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis, Femur Head Necrosis, Congenital Dislocations
- Trial name
- NCT02230826
- Where
- 13 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Corin
Total Hip Replacement, Total Knee Replacement
Dressing-related Experiences and Surgical Site Self-care in Hip and Knee Replacement: an Observational Cohort Study
The goal of this prospective observational cohort study is to investigate dressing-related experiences and surgical site self-care in patients who are undergoing a total hip or knee replacement.
- Trial name
- DRESS-X (NCT07471243)
- Testing
- Wound Dressing Material
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Bournemouth University
Surgical Education, Operating Room Nursing
Digital Gamification vs. Traditional Training for Hip Replacement Instrument Table Setup (ORNurse)
This randomized controlled trial aims to compare the effectiveness of a digital gamification-based training method and a traditional training method on instrument table layout skills in total hip replacement surgery.
- Conditions
- Surgical Education, Operating Room Nursing, Educational Technology
- Trial name
- ORNurse (NCT07194148)
- Testing
- Gamified Digital Education (ORNurse: Steril Setup 1.0), Traditional Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- DERYA ESENKAYA
Analgesics, Opioid, Anesthesia, Spinal
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Pain management after total hip replacement is one of the most important aspects of postoperative care for patients and clinicians alike.
- Conditions
- Analgesics, Opioid, Anesthesia, Spinal, Total Hip Replacement, Adverse Anesthesia Outcome
- Trial name
- NCT06878014
- Testing
- Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone
- Where
- 3 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Silesia
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Hip Osteoarthritis, Hip Arthroplasty Replacement
Post-Operative Spinal Block Duration and Pain Relief After Hip Replacement Surgery: Comparing Single-Shot Spinal Ropivacaine and Bupivacaine
This study aims to determine whether isobaric ropivacaine is more suitable than isobaric bupivacaine for spinal anesthesia in outpatient total hip arthroplasty (THA).
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Postoperative Pain After Ambulatory Surgery
- Trial name
- ROBUTHA (NCT07631091)
- Testing
- Spinal Anesthesia with Ropivacaine 15 mg (5 mg/ml), Spinal Anesthesia with Bupivacaine 11 mg (5 mg/ml)
- Volunteers
- 176 people
- Sponsor
- University of Turku
Osteoarthritis, Osteoarthritis (OA) of the Knee
Feasibility of Choose to Move Replacement Ready
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis, Hip, Total Knee Arthroplasty; Total Hip Arthroplasty
- Trial name
- CTM-RR (NCT07069179)
- Testing
- Choose to Move Replacement Ready
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Osteo Arthritis Knee and Hip
Total Hip Replacement: an Investigation of Robotic-assisted Versus conVentional Surgery and Patient-centred outcomEs
Hip replacement is highly effective for severe osteoarthritis, but some patients continue to experience symptoms or complications.
- Trial name
- THRIVE (NCT07907185)
- Testing
- MAKO Robotic System (Stryker, USA), Conventional Total Hip Arthroplasty
- Volunteers
- 90 people
- Sponsor
- Hamilton Health Sciences Corporation
Anesthesia for Hip Surgery
PENG Block vs ESPB in Elderly Undergoing Hip Surgeries
To our knowledge, the comparison between the ultrasound-guided lumbar erector spinae plane block and the pericapsular nerve group block has not been investigated before in previous literature.
- Trial name
- NCT06993376
- Testing
- PENG block, ESPB
- Volunteers
- 56 people
- Sponsor
- Cairo University
PENG Block
Efficacy of Dexmedetomidine As an Adjuvant to Bupivacaine in Pericapsular Nerve Group Block in Hip Replacement Surgeries
Our aim will be to investigate the efficacy of dexmedetomidine as an adjuvant to bupivacaine in ultrasound guided pericapsular nerve group (PENG) block for postoperative analgesia in hip replacement surgeries.
- Trial name
- NCT06736392
- Testing
- Ultrasound guided Pericapsular Nerve Group Block, Isobaric Bupivacaine 0. 25%, 20 ml isobaric bupivacaine 0.25% and 1.5μg/kg dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Assiut University
Prehabilitation, Preoperative Care
Preoperative Optimization Before Total Hip or Knee Replacement Surgery
Preoperative Optimisation prior to Hip and Knee Arthroplasty (PrOpE) Many patients scheduled for planned hip or knee replacement surgery have health conditions that may affect recovery, such as reduced physical fitness…
- Trial name
- PrOpE (NCT07394582)
- Testing
- Prehabilitation
- Where
- Austria
- Volunteers
- 180 people
- Sponsor
- Medical University Innsbruck
Arthroplasty Replacement, Knee, Arthroplasty Total Hip Replacement
A Prospective, Single-arm, Trial to Determine Contamination Rates When Using an Antibacterial Incise Drape During Orthopedic Surgery
The goal of this clinical study is to generate data on the intended use of a chlorhexidine gluconate (CHG)-impregnated antimicrobial incise drape.
- Trial name
- NCT07356323
- Testing
- 3M™ Ioban™ CHG Chlorhexidine Gluconate Incise Drape (2% w/w CHG)
- Where
- 2 sites in United States
- Volunteers
- 179 people
- Sponsor
- Solventum US LLC
Pain Management, Arthroplasty
Effect of Preoperative Pain Education on Anxiety, Pain, and Analgesic Use in Total Knee and Hip Replacement Patients
This randomized controlled trial evaluates whether a standardized preoperative pain education session delivered by a nurse reduces postoperative pain intensity and surgical anxiety among adult elective orthopedic surgery patients…
- Conditions
- Pain Management, Arthroplasty, Knee Replacement, Hip Replacement
- Trial name
- Pain-Anxiety (NCT07362589)
- Testing
- Pain education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Yeditepe University
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Hip Replacement Surgery, Hip Replacement, Total
OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study
Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis.
- Conditions
- Hip Replacement Surgery, Hip Replacement, Total, Hip Pain, Hip Arthroplasty
- Trial name
- NCT07017192
- Testing
- SIFI Block, ESP block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza