Clinical trials: Hip Surgeries, open to volunteers
Hip Fracture Surgeries, Intertrochanteric Fracture
Monitored Anesthesia Care and Soft Tissue Infiltration With Local Anesthesia Feasibility Trial
The purpose of this study is to establish preliminary efficacy of Monitored Anesthesia Care and Soft Tissue Infiltration with Local Anesthesia (MAC-STILA) on severity of post operative delirium and secondary outcomes in patients…
- Conditions
- Hip Fracture Surgeries, Intertrochanteric Fracture, Femoral Hip Fracture
- Trial name
- MAC-STILA (NCT07897656)
- Testing
- Monitored Anesthesia Care (MAC), Soft Tissue Infiltration with Local Anesthetic (STILA), General Anesthesia
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- NYU Langone Health
Juvenile; Scoliosis, Scoliosis Idiopathic
Studying Melatonin and Recovery in Teens
The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgerySMART (NCT06093477)
- Testing
- Fast-Dissolve Melatonin Pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Cerebral Palsy, Hip Surgery Corrective
Tranexamic Acid to Reduce Blood Loss After Varus Derotation Osteotomy
TABLO (Tranexamic Acid to reduce Blood Loss after varus derotation Osteotomy) is a clinical trial of postoperative tranexamic acid vs placebo in non-ambulatory children with cerebral palsy (CP) undergoing reconstructive hip…
- Conditions
- Cerebral Palsy, Hip Surgery Corrective, Tranexamic Acid Use, Blood Loss, Surgical
- Trial name
- TABLO (NCT07672158)
- Testing
- Tranexamic Acid (IV)
- Where
- Australia
- Volunteers
- 52 people
- Sponsor
- Murdoch Childrens Research Institute
Total Hip Arthroplasty, Computer-Assisted Surgery
Pre-Op THA Modelling
Replacing diseased hip joints with prosthetic implants in a procedure called total hip arthroplasty (THA) is associated with high rates of patient satisfaction, pain relief, and functional improvement when the implant is…
- Trial name
- NCT05221554
- Testing
- Imageless computer-navigated THA surgery, Standard of care THA surgery, CT-based Computer-navigated THA surgery
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Sarcopenia in Elderly, Osteoarthritis (OA)
Impact of Pre-operative Sarcopenia on Functional Recovery After Hip Arthroplasty in Older Adults
This single-centre, exploratory study at Montpellier University Hospital will investigate whether having low muscle mass and strength before hip-replacement surgery, a condition called sarcopenia, impact the return to everyday…
- Conditions
- Sarcopenia in Elderly, Osteoarthritis (OA), Hip Fracture Surgeries
- Trial name
- HIP-REGEN (NCT07429955)
- Testing
- Total hip replacement, Blood sampling, Muscle biopsies
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Hip Surgery, Hip Arthroplasty
The Quadro-Iliac Plane (QIP) Block in Hip Surgery
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including…
- Trial name
- QIP in hip (NCT07591311)
- Testing
- Fascia iliaca block (FIB)
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- San Giovanni di Dio Hospital
Surgery, Knee Arthropathy
Evaluation of Arthroplasty Treatment
The aim of the study is to examine patients after knee and hip endoprosthesis in the longitudinal section and to evaluate the surgical outcome.
- Conditions
- Surgery, Knee Arthropathy, Hip Arthropathy, Prosthetic-joint Infection
- Trial name
- Endo-GEP (NCT07799818)
- Testing
- Joint replacement
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bonn
Hip Replacement Surgery, Hip Replacement, Total
OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study
Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis.
- Conditions
- Hip Replacement Surgery, Hip Replacement, Total, Hip Pain, Hip Arthroplasty
- Trial name
- NCT07017192
- Testing
- SIFI Block, ESP block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Femoral Neck Fractures, Geriatric Hip Fracture
Efficacy of Oral Nutritional Supplement in Femoral Neck Fracture Patients Undergoing Hip Arthroplasty
This study aim to compare the efficacy of oral nutritional supplementation (ONS) in femoral neck fracture patients undergoing hip arthroplasty compared with placebo.
- Conditions
- Femoral Neck Fractures, Geriatric Hip Fracture, Hip Fracture, Post Surgery Recovery, Muscle Resilience
- Trial name
- NCT07780006
- Testing
- Oral nutritional supplementation
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Fascia Iliaca Block, Liposomal Bupivacaine
Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Surgery
Patients after hip surgery often suffer from severe pain. Inadequate analgesia increases the risk of postoperative delirium, myocardial injury, and other complications.
- Conditions
- Fascia Iliaca Block, Liposomal Bupivacaine, Postoperative Pain, Hip Surgery
- Trial name
- NCT07643792
- Testing
- Liposomal bupivacaine (LB), Plain bupivacaine
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Peking University First Hospital
Hip Fracture, Perioperative Myocardial Injury
Nerve Block and Perioperative Myocardial Injury in Elderly Hip Fracture
This single-center, retrospective cohort study evaluates whether a single preoperative peripheral nerve block can reduce the risk of perioperative myocardial injury in elderly patients undergoing delayed hip fracture surgery…
- Conditions
- Hip Fracture, Perioperative Myocardial Injury, Myocardial Injury After Noncardiac Surgery
- Trial name
- PNB-CARD (NCT07751146)
- Testing
- PNB, Non-PNB
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\)
Suzetrigine in Total Hip Arthroplasty
Total hip and knee joint replacements are among the most common and painful orthopedic procedures performed worldwide, often requiring intensive analgesia to support early ambulation and recovery.
- Conditions
- Total Hip Arthroplasty (THA), Total Hip Arthroplasty \(THA\), Total Hip Replacement, Total Hip Replacement Surgery
- Trial name
- NCT07226700
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hip-fracture, Surgery
Intravenous vs Oral Acetaminophen in Postoperative Hip Fracture Adult Patients
The INTACT-HIP trial study will evaluate feasibility of conducting a randomized, double-blinded controlled trial comparing postoperative treatment with intravenous (IV) acetaminophen versus oral acetaminophen, in older adults…
- Trial name
- INTACT-HIP (NCT05425355)
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University Health Network, Toronto
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Hip Fracture Surgeries
Comparative Study Between Pericapsular Nerve Group Block (PENG) And Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block for Positioning Analgesia Prior to Spinal Anesthesia in Hip Fracture Patients
To evaluate and compare the effectiveness of the Pericapsular Nerve Group (PENG) block alone versus the PENG block combined with the Lateral Femoral Cutaneous Nerve (LFCN) block in providing adequate analgesia for patient…
- Trial name
- NCT07687290
- Testing
- PENG Block, LCFN block, bupivacaine 0.25%.
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Hip Fractures (ICD-10 72.01-72.2)
Improving Shared DECISion-making in oldEr Hip Fracture Patients Living With Frailty
Title Improving shared decision-making in older hip fracture patients living with frailty Aim To use routinely information normally collected by the NHS, and interviews with patients, families, and healthcare professionals, to…
- Conditions
- Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Hip Fractures (ICD-10 72.01-72.2), Hip Fracture, Hip Fracture, Post Surgery Recovery, Muscle Resilience
- Trial name
- DECIDE-HIP (NCT07687108)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Southampton
Patients Undergoing Orthopedic Hip Surgery Under Spinal Anesthesia, Orthopedic Hip Sugery in Eldely Patients
Comparison of Norepinehrine Versus Phenylepherine Infusion for Prevention of Post-spinal Hypotension
This prospective randomized double-blinded clinical trial aims to compare the efficacy and hemodynamic effects of prophylactic norepinephrine infusion versus phenylephrine infusion for prevention of spinal anesthesia-induced…
- Trial name
- NCT07662408
- Testing
- Norepinephrine, Phenylephrine
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hip Surgery, Rehabilitation Program
Digitally Assisted Rehabilitation at Home for Older Adults After Hip Surgery (GRIMSEL)
The goal of this clinical trial is to learn if a 12-week digitally supported, multimodal home rehabilitation program using the medical application Akina is as effective compared to routine care regarding functional independence…
- Conditions
- Hip Surgery, Rehabilitation Program, Geriatrics Rehabilitation, Digital Health Intervention
- Trial name
- GRIMSEL (NCT07658664)
- Testing
- Digitally supported multimodal rehabilitation program, routine care
- Volunteers
- 66 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern