Clinical trials: Hip and Knee Replacement Surgeries
Total Knee Replacement Surgery, Total Hip Replacement Surgery
Xperience™ vs Normal Saline Irrigation Solution for Decreasing Bioburden After Primary Total Hip and Knee Arthroplasty
The purpose of this study is to evaluate the effectiveness of Xperience, a no rinse antimicrobial solution, on joint infection rates in patients undergoing total hip (THA) and total knee (TKA) arthoplasty surgery.
- Trial name
- NCT05577936
- Testing
- XPERIENCE Advanced Surgical Irrigation, Standard of Care Irrigation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Postoperative Cognitive Dysfunction
Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up
The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (>60y) after total hip or knee replacement surgery.
- Trial name
- NCT01103752
- Testing
- no intervention, descriptive study
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Lene Krenk
Arthroplasty Complications, Amputation
Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings
Negative pressure dressings are currently widely used in wound management. Their use is gradually being extended to surgical scars.
- Conditions
- Arthroplasty Complications, Amputation, Prosthesis-Related Infections
- Trial name
- BERLYTZ (NCT04520841)
- Testing
- Prevena TM, Dry dressing
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Orthopedic Procedure
Implementation of Fast-track Surgery Program for Total Hip and Knee Replacement and the Evaluation of the Risks and Benefits for the Patient
Implementation of Fast-track surgery for total hip replacement and total knee replacement and evaluation of the risks and benefits for the patients.
- Trial name
- NCT03028779
- Testing
- Fast-track Total Hip and knee arthroplasty
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients
Hip and knee replacement surgery is commonly performed in older adults. After surgery, many patients experience pain, limited movement, and sleep problems.
- Trial name
- NCT07354542
- Testing
- Virtual Reality-Based Relaxation, Traditional Relaxation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Metallosis, Pain
Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty
The purpose of this research is to understand whether patients who previously had total hip or total knee replacement experience memory, thinking or heart problems.
- Conditions
- Metallosis, Pain, Total Hip Replacement, Total Knee Replacement
- Trial name
- NCT04166539
- Testing
- Questionnaires, Interviews, Blood draw
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoarthritis
Pain Expectations in Subjects With Osteoarthritis
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat…
- Trial name
- NCT02155257
- Testing
- Modafinil, Gabapentin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pulmonary Embolism
Prophylaxis Against DVTs After Primary Hip and Knee Replacement Surgery
The purpose of this research is to find a better way to prevent the post operative development of clots in the deep veins of the legs (also called Deep Vein Thrombosis or DVT).
- Trial name
- DVT (NCT00767559)
- Testing
- warfarin, Fondaparinux:
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- The New England Baptist Hospital
Spinal Anesthesia
Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone
In the current healthcare system, a short length of stay is paramount, for medical, functional, and financial reasons. Most patients undergoing hip and knee replacement at Hôpital Montfort institution receive spinal anesthetic…
- Trial name
- NCT04280939
- Testing
- spinal anesthesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hopital Montfort
Pain, Spinal Surgeries, Hip and Knee Joint Replacement, Adverse Events
RAHM Foundation Retrospective Study of Various Diseases
This is a retrospective data collection on treatment of various disorders. This registry will include a variety of different products, implants, technologies and procedures.
- Trial name
- NCT02359786
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rahm Foundation
MYOCARD INFARCTUS, Non Cardiac Surgery
Myocardial Injury After Noncardiac Surgery (MINS) in Patients Undergoing Knee and Hip Arthroplasty
The aim of this study is to determine the incidence of myocardial injury after noncardiac surgery (MINS) in patients undergoing elective total knee or hip arthroplasty, and to identify the demographic, clinical, laboratory, and…
- Conditions
- MYOCARD INFARCTUS, Non Cardiac Surgery, ARTHROPLASTY, REPLACEMENT; ANESTHESIA
- Trial name
- MINS (NCT07098468)
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Staphylococcal Infections
StaphVAX Immunogenicity and Safety in Orthopaedic Joint Surgery
Staphylococcus aureus (S. aureus) is the most common pathogen encountered in infections associated with orthopedic surgery. StaphVAX® is a bivalent S.
- Trial name
- NCT00211965
- Testing
- S. aureus Types 5 and 8 Capsular Polysaccharide Conjugate
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Nabi Biopharmaceuticals