Clinical trials: Hospice Care
Advance Care Planning
Advance Care Planning With Formerly Homeless Older Adults Residing in Permanent Supportive Housing
The homeless population is aging, with an increasing proportion of individuals over age 50 who experience accelerated aging, high rates of mortality, and a high risk of not having their wishes honored at the end of life.
- Trial name
- ACP-PSH (NCT06239896)
- Testing
- Facilitated Group ACP Session, Facilitated one-on-one ACP visits
- Where
- 6 sites in United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Caregiver, Disabled Veterans
Helping Invested Families Improve Veterans Experiences Study
The purpose of this study is to evaluate a caregiver skill training program (HI-FIVES), offered as a part of a randomized control trial to caregivers of Veterans referred to home and community-based long-term care.
- Conditions
- Caregiver, Disabled Veterans, Referred to Long-term Care, Residing at Home
- Trial name
- HI-FIVES (NCT01777490)
- Testing
- Helping Invested Families Improve Veterans Experiences - Control, Helping Invested Families Improve Veterans Experiences - HI FIVES
- Where
- United States
- Volunteers
- 484 people
- Sponsor
- VA Office of Research and Development
Frail Elderly Syndrome
Implementing, Evaluating, and Scaling Up of the Strengthening a Palliative Approach in Long Term Care (SPA-LTC) Program
This study will evaluate the implementation of the Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) program using a cross-jurisdictional, effectiveness-implementation type II hybrid design (dual testing of clinical…
- Trial name
- NCT03935997
- Testing
- Strengthening a Palliative Approach in Long-Term Care (SPA-LTC) Program
- Where
- 4 sites in Canada
- Volunteers
- 594 people
- Sponsor
- McMaster University
Dementia
The Hospice Advanced Dementia Symptom Management and Quality of Life Trial (HAS-QOL)
The Aliviado Dementia Care Program (formerly known as the Dementia Symptom Management at Home Program, or DSM-H) was developed to implement dementia friendly care for persons with Dementia and their caregivers living in the…
- Trial name
- NCT04175977
- Testing
- Aliviado Dementia Care-Hospice Edition QAPI program, Usual Care
- Where
- United States
- Volunteers
- 44,143 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Aging Problems
Enhancing Care of the Aged and Dying in Prisons Ph II
The mission of corrections is to provide custody, control and care for incarcerated individuals. United States prisons are required by constitutional law to provide adequate care for growing numbers of older inmates who will…
- Trial name
- NCT03055429
- Testing
- Full Scale Unit
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Critical Illness
Multi-component Family Support Tool Intervention (FST)
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive…
- Trial name
- FST (NCT05019261)
- Testing
- Multi-component Family Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
End of Life Care, Cancer
Serious Illness Communication Project
The purpose of the study is to evaluate the impact of implementing a "Serious Illness Conversation Guide" to guide patient/family-clinician discussions and planning about end-of-life care decisions.
- Trial name
- NCT01786811
- Testing
- Training
- Where
- United States
- Volunteers
- 994 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Heart Failure, Heart-assist Devices
PCORI-1310-06998 Trial of a Decision Support Intervention for Patients and Caregivers Offered Destination Therapy Heart Assist Device
The left ventricular assist device (LVAD) is growing rapidly among people dying from end-stage heart failure who are unable to get a heart transplant.
- Trial name
- DECIDE-LVAD (NCT02344576)
- Testing
- DT LVAD Decision Support Intervention
- Where
- 6 sites in United States
- Volunteers
- 445 people
- Sponsor
- University of Colorado, Denver
Terminal Illness, Xerostomia
A Randomized Controlled Trial Evaluating the Effectiveness of a Salvia-based Mouthwash in Palliative Care
This study examines the effectiveness of an herbal mouthwash made from salvia in maintaining good oral health among patients in palliative care.
- Trial name
- NCT02067572
- Testing
- Saline mouthwash, Salvia mouthwash
- Where
- Norway
- Volunteers
- 88 people
- Sponsor
- Lovisenberg Diakonale Hospital
Hospice, End of Life
Tandem VR: Synchronized Nature-Based Experiences in Virtual Reality for Hospice Patients and Their Caregivers
Background: Nature-based virtual reality (VR) and other outdoor experiences in head-mounted displays (HMDs) offer powerful, non-pharmacological tools for hospice teams to help patients undergoing end-of-life (EOL) transitions.
- Conditions
- Hospice, End of Life, Palliative Care, Pain
- Trial name
- NCT06186960
- Testing
- Tandem Virtual Reality
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Upstate
Advanced Cancer, Terminal Malignant Tumors
Nurses' Competence and Role in Survival Prediction and Prognostic Communication
[Background] Nurses' roles in survival prediction and prognostic communication have historically been limited due to role delineation, lack of formal training, and cultural norms.
- Conditions
- Advanced Cancer, Terminal Malignant Tumors, Hospices
- Trial name
- NCT06962553
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cancer
Palliative Care Yields Cancer Wellbeing Support
The goal of this study is to evaluate the effectiveness of a programme for transitional palliative cancer care (Pal-Cycles) in seven countries (the Netherlands, Germany, United Kingdom, Hungary, Poland, Romania and Portugal) and…
- Trial name
- Pal-Cycles (NCT06259136)
- Testing
- A transitional palliative care intervention
- Where
- Netherlands
- Volunteers
- 1,050 people
- Sponsor
- Radboud University Medical Center
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Ovarian Cancer, Cervical Cancer
Ensuring Communication in Hospice by Oncology Study (ECHO)
The goal of this study is to determine if scheduled communication with the oncology team through phone calls is helpful to caregivers with the transition to hospice care.
- Conditions
- Ovarian Cancer, Cervical Cancer, Uterine Cancer, Head and Neck Cancer
- Trial name
- NCT02069769
- Testing
- communication with oncology team
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Advance Care Planning, End of Life Care
Advance Care Planning for Critical Care - A Prelude to Breaking Barriers
Advance Care Planning (ACP) is a process of 'reflection and communication, in which a person with decision-making capacity makes decisions regarding their future health and/or personal care in the event that they become incapable…
- Trial name
- NCT02797444
- Testing
- semi-structured interviews
- Where
- 2 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Mitochondrial Diseases
EPI-743 for Mitochondrial Respiratory Chain Diseases
This study will evaluate the safety and efficacy of EPI-743 in participants with severe mitochondrial respiratory chain diseases who are considered to be within 90 days of end-of-life care.
- Trial name
- NCT01370447
- Testing
- EPI-743
- Where
- 16 sites in United States
- Sponsor
- PTC Therapeutics
Metastatic Cancer
A Trial Investigating the Effect of Specialised Palliative Care on Symptoms, Survival, Economical Factors and Satisfaction
Specialised palliative care (SPC) seeks to relieve suffering and improve quality of life in patients with a life threatening disease such as advanced cancer. Many patients with advanced cancer are not in contact with SPC.
- Trial name
- DanPaCT (NCT01348048)
- Testing
- Specialised palliative care (SPC)
- Where
- 6 sites in Denmark
- Volunteers
- 306 people
- Sponsor
- Bispebjerg Hospital
Pain
The ACTIVE Intervention to Improve Hospice Care
The ACTIVE Intervention to Improve Hospice Caregiver Pain Management The major goal of this project is to implement and test this promising intervention in three hospice programs.
- Trial name
- NCT01211340
- Testing
- ACTIVE
- Where
- 2 sites in United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Palliative Care
Improving Palliative Care Through Teamwork
One in three Americans dies in a nursing home (NH) or in a hospital, shortly following transfer from a long-term care facility. The proportion of deaths occurring in NHs is projected to increase to 40% by 2020.
- Trial name
- IMPACTT (NCT01990742)
- Testing
- Palliative Care Team (PCTeam)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Terminal Illness
iLIVE Volunteer Study
The aim of this study is to develop and evaluate the implementation of an international volunteer training programme to support patients dying in the hospital setting and their families. It has the following objectives: 1.
- Trial name
- NCT04678310
- Testing
- Support from the hospital palliative and end of life care volunteer service (developed for this study).
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- University of Liverpool