Clinical trials: Hospital Medicine
Postoperative Recovery
Association of Perioperative Daily Steps and Postoperative Recovery Among Surgical Patients
Walking is the most common, simple and convenient way of exercise with the lowest cost. Studies have shown that daily steps are related to important health outcomes such as cardiovascular events and all-cause mortality.
- Trial name
- NCT04934657
- Testing
- no intervention
- Where
- China
- Volunteers
- 487 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Atelectasis
Application of High Flow Nasal Cannula for Prevention of Post-extubation Atelectasis in Children Undergoing Surgery
postoperative atelectasis observation by ultrasound after application of high flow nasal cannula oxygenation
- Trial name
- NCT03817177
- Testing
- high flow nasal cannula oxygenation, nasal prong
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Sepsis
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis
Sepsis is a life-threatening disease characterized by multi-organ failure due to dysregulated host response to infection, with high global mortality of 30-50%.
- Trial name
- NCT04427371
- Testing
- the levels of pyroptosis
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jianfeng Xie
Non Small Cell Lung Cancer
Low Dose Weekly Docetaxel Versus Pemetrexed in Previously Treated Advanced Non-Small-Cell Lung Cancer
Docetaxel and pemetrexed have been validated for previously treated advanced non-small cell lung cancer (NSCLC); however, tolerability is a concern with the docetaxel (tri-weekly 75 mg/m2 schedule).
- Trial name
- NCT01004601
- Testing
- docetaxel, pemetrexed
- Where
- Taiwan
- Volunteers
- 179 people
- Sponsor
- Chang Gung Memorial Hospital
Delirium - Postoperative, Cardiac Surgery
Lemborexant to Prevent Post-operative Delirium in Cardiac Surgery Patients
Post-operative delirium is a common complication following cardiac surgery and is associated with increased 1 year mortality. Currently there are no drug therapies to prevent delirium.
- Conditions
- Delirium - Postoperative, Cardiac Surgery, Cardiac Surgery Subjects, Orexin Antagonist
- Trial name
- PROTEX (NCT06648681)
- Testing
- Lemborexant 5 mg
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Vasculitis
The Effect of Some Drugs Used in Treatment of Vasculitis on the Complement System in Children
Vasculitis denotes affection of small to medium sized vessels by polyangitis. Antineutrophil cytoplasmic antibodies (ANCA) are immunoglobulin G (IgG) autoantibodies directed against constituents of neutrophil granules leading to…
- Trial name
- NCT03692416
- Testing
- Ibuprofen, Prednisone, Methotrexate
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Safety Issues
Study to Assess the Impact of Medication Reconciliation at Hospital Admission on Healthcare Outcomes
Medication reconciliation is a systematic process by which health care professionals obtain the most complete and accurate information about the drugs regularly taken by patients.
- Trial name
- MedRec (NCT03654963)
- Testing
- Medication reconciliation
- Where
- 2 sites in Switzerland
- Volunteers
- 1,702 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Perioperatoire Medicine, Surgery
Evaluation of a Structured Hospital-Community Care Follow-up Based on Perceived Quality of Care After Surgery, Aimed at Reducing Persistent Opioid Use in Primary Care: a Pragmatic Randomized Controlled Trial
The OPTIMISTE program is based on a structured postoperative follow-up centered on patients' subjective perception of recovery using validated Patient Reported Outcome Measures (PROMs), including the mQoR-15f score.
- Trial name
- OPIOID CITY FR (NCT07659730)
- Testing
- Patient-Reported Outcomes-based perioperative follow-up (QoR-15 focus)
- Volunteers
- 772 people
- Sponsor
- University Hospital, Strasbourg, France
Smoking Cessation
Nicotine Replacement Provided at a Tertiary Care Hospital
The purpose of this study is to show that a patient-centered survey asking about smoking habits, with the option for nicotine replacement therapy (NRT) will increase the prescription rates among health care providers (HCP).
- Trial name
- N-PATCH (NCT01614054)
- Testing
- Survey of patient's smoking habits
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Aging, Polypharmacy
Biological Aging, Medication, Malnutrition and Inflammation Among Acutely Ill and Healthy Elderly.
In this study, the investigators will investigate and characterize acute medical patients in order to optimize patient courses in the acute care departments, especially with regard to polypharmacy and undernourishment.
- Conditions
- Aging, Polypharmacy, Malnutrition, Inflammation
- Trial name
- FAM-CPH (NCT03052192)
- Where
- Denmark
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Medical Cannabis
Evaluation of Interprofessional Relations Between Primary Care and Hospital Centers in the Experimentation of Medical Cannabis in France Carried Out by the ANSM (ECIPCanna)
An observational study to explore inter-professional relations and perceptions around the experimentation of medical cannabis, conducted by the French National Agency for Safety and Health.
- Trial name
- ECIPCanna (NCT06597097)
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Brest
Substance Use Disorders, Infection, Soft Tissue
Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) for Invasive Infections Related to Opioid Use
Standard of care for patients with opioid use disorder and complicated infections is discharge to subacute nursing facilities on IV antibiotics until completion of treatment course.
- Conditions
- Substance Use Disorders, Infection, Soft Tissue, Bacteremia, Osteomyelitis Acute
- Trial name
- AIM-STOP (NCT05521880)
- Testing
- Oritavancin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Maryland, Baltimore
Hepatitis C
Registry-based HCV Care Cascade Navigation at Atlanta's Grady Memorial Hospital
This study seeks to implement and evaluate a data-driven case navigation system for hepatitis C virus (HCV) treatment among persons who are either actively injecting drugs or who are receiving opioid substitution therapy (OST).
- Trial name
- EZ-C (NCT03441542)
- Testing
- Data-assisted Case Navigation, Standard of Care
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Opinion Research Center
Cataract, Surgery
Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population
The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the…
- Conditions
- Cataract, Surgery, Compliance, Patient, Compliance, Medication
- Trial name
- NCT05157113
- Testing
- Dropless Regimen, Standard Regimen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Francisco
Appointments and Schedules, Outpatient Clinics, Hospital
Causes of Nonattendance at Scheduled Outpatient Appointments
Our aim was to identify the causes non-attendance at scheduled appointments at the Clinical Medicine Outpatient care system at the Italian Hospital of Buenos Aires (HIBA).
- Trial name
- AU2 (NCT02113488)
- Where
- Argentina
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Disease, Delivery of Healthcare
Interprofessional Collaborative Communication in Acute Care Hospital Teams
Collaborative practice may improve patient outcomes in specific disease conditions and health care settings. The SCRIPT Programme is an intervention to implement informal, but structured, communication etiquette between members…
- Trial name
- SCRIPT (NCT00466297)
- Testing
- Face-to-face communication interactions
- Where
- 2 sites in Canada
- Volunteers
- 1,000 people
- Sponsor
- Sunnybrook Health Sciences Centre
Attendance
Impact of Automated Calls on Pediatric Patient Attendance in Chile
Missed health care appointments present a serious challenge to patient care. Especially in government funded health systems like that of Chile, missed appointments can lead to delayed care, wasted resources, and escalating costs.
- Trial name
- Health Call (NCT02442089)
- Testing
- Health Call
- Where
- Chile
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pneumonia
M-ROSE Combined With mNGS in Severe Hospital-acquired Pneumonia
The purpose of this study is to determine the value of M-ROSE（microbiological rapid on-site evaluation）in severe hospital-acquired pneumonia.
- Trial name
- NCT05300776
- Testing
- M-ROSE analysis
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Chinese PLA General Hospital
Multi Drug Resistant Organisms
Infection Risk Associated With Digestive MDRO Carriage in Hospitalized Patients
This study aims to evaluate the impact of digestive carriage of multidrug-resistant organisms (MDRO) on the risk of healthcare-associated infections in hospitalized adult patients.
- Trial name
- NCT07134270
- Testing
- MDRO Rectal Screening, 30-Day Telephone Follow-Up
- Where
- Romania
- Volunteers
- 400 people
- Sponsor
- Valeriu Gheorghita
Total Knee Arthroplasty; Total Hip Arthroplasty
Health Partner Evaluation at Princeton
This is a prospective, single-center, randomized, comparative, controlled study. Penn Medicine Princeton Medical Center will enroll a total of 296 subjects (18 years or older) who are electing to have total knee or hip…
- Trial name
- NCT03386786
- Testing
- Health Partner, Standard Care
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- DePuy Orthopaedics