Clinical trials: Hot Flashes
Vasomotor Symptoms Associated With Menopause
Herbal Alternatives for Menopause Symptoms (HALT Study)
Surveys indicate that 25 to 33% of women have moderate to severe menopausal symptoms including hot flashes, night sweats, and disturbed sleep.
- Trial name
- NCT00169299
- Testing
- Black cohosh, Multibotanical preparation, Multibotanical preparation + dietary soy counseling
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hot Flashes
A Study to Assess Long-term Safety of Fezolinetant Given to Japanese Women Going Through Menopause
Hot flashes are the most common reason women going through menopause seek medical attention. Hormone replacement therapy, or HRT, is most often prescribed to treat hot flashes.
- Trial name
- Starlight 3 (NCT06206421)
- Testing
- Fezolinetant
- Where
- 24 sites in Japan
- Volunteers
- 277 people
- Sponsor
- Astellas Pharma Inc
Hot Flashes, Heart Rate
Influence of Nebivolol on Postmenopausal Women
After menopause the coronary artery disease (CAD) risk increases rapidly to an equivalent risk of men with the same age. The rising incidence of CAD could be a subsequent decline of endogenous estrogen blood levels after the…
- Conditions
- Hot Flashes, Heart Rate, Blood Pressure, Endostatin
- Trial name
- NCT01161823
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Hot Flashes
Efficacy and Safety of a Topical Estradiol Gel for Treatment of Postmenopausal Symptoms
The purpose of this study is to determine the efficacy and safety of a topical estradiol gel for the treatment of hot flushes in postmenopausal women.
- Trial name
- NCT00391417
- Testing
- estradiol gel
- Volunteers
- 431 people
- Sponsor
- BioSante Pharmaceuticals
Hot Flashes
Study of Gabapentin Extended Release (G-ER)in the Treatment of Vasomotor (Hot Flashes/Hot Flushes) Symptoms in Postmenopausal Women.
Depomed's Gabapentin Extended Release is an investigational, extended release formulation of gabapentin that is being studied for the treatment of hot flashes in postmenopausal women
- Trial name
- NCT00777023
- Testing
- Gabapentin Extended-Release (G-ER) 1200 mg, Gabapentin Extended-Release (G-ER) 1800 mg
- Where
- 45 sites in United States
- Volunteers
- 565 people
- Sponsor
- Depomed
Breast Cancer
Study Evaluating Hot Flashes in Hormone Sensitive Breast Cancer
The validation of the HFRDIS questionnaire in French will allow the use in common practice of this questionnaire in consultation in order to have a concrete and reproducible assessment of the impact of hot flashes on the daily…
- Trial name
- HOTSHOT (NCT04775043)
- Testing
- HFRDIS questionnaire completion
- Where
- France
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Institut Curie
Menopause, Hot Flashes
Gabapentin for Insomnia Symptoms and Nighttime Vasomotor Symptoms (VMS) in Peri- and Postmenopausal Women
The broad goal of this study is to obtain pilot data to determine the tolerability and preliminary efficacy of the non-hormonal agent gabapentin for insomnia symptoms and nighttime vasomotor Symptoms (VMS) when open-label…
- Conditions
- Menopause, Hot Flashes, Vasomotor Disturbance
- Trial name
- NCT02040532
- Testing
- Gabapentin
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Menopause, Menopausal Hormone Therapy
A Retrospective and Prospective Clinical Registry for Data Collection of Perimenopausal, Menopausal and Premature Ovarian Insufficiency Women
This study is designed as on observational, retrospective, and prospective clinical registry aimed at collecting comprehensive real-world data on women in perimenopause, menopause, and with premature ovarian insufficiency (POI)…
- Conditions
- Menopause, Menopausal Hormone Therapy, Menopause Surgical, Menopause Related Conditions
- Trial name
- NCT07606326
- Volunteers
- 5,000 people
- Sponsor
- IRCCS San Raffaele
Breast Cancer, Hot Flashes
Hormone Replacement Therapy in Relieving Menopausal Symptoms in Postmenopausal Women With Previous Stage I or Stage II Breast Cancer
RATIONALE: Hormone replacement therapy may be effective in relieving symptoms of menopause, such as hot flashes, night sweats, and vaginal dryness, without causing a recurrence of breast cancer.
- Conditions
- Breast Cancer, Hot Flashes, Menopausal Symptoms, Osteoporosis
- Trial name
- NCT00079248
- Testing
- therapeutic progesterone, conjugated estrogens
- Where
- United Kingdom
- Sponsor
- Institute of Cancer Research, United Kingdom