Clinical trials: Hydrocephaly
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Developing the ABEP-H, Determining the Effect of ABEP-H
The Effect of an Avatar-Based Education Program on Shunt Complications and Parents' Knowledge and Care Skills
Hydrocephalus is a common childhood neurosurgical disease. Ventriculoperitoneal (VP) shunt is usually used in the treatment of hydrocephalus. However, VP shunt may have some complications.
- Trial name
- NCT05370131
- Testing
- Avatar-Based Education Program in Hydrocephalus (ABEP-H)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Hydrocephalus, Alzheimer Disease
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
The Researchers are trying to test a MR imaging method for detection of Cerebral Spinal Fluid (CSF) flow in the brain to help diagnosis and better understand diseases that affect brain function.
- Trial name
- NCT04099823
- Testing
- MRI screening form, Urine pregnancy test, MR brain
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
The iNPH Patients Scheduled for VP or LP Shunt Procedures
Factors Associated With Post-induction Hypotension in iNPH Patient Undergoing VP and LP Shunt
This study is a retrospective work involving the review of patients who were scheduled for VP or LP shunt in Siriraj Hospital, Mahidol University, Thailand.
- Trial name
- NCT05183061
- Testing
- Ehedrine Norepineprine
- Where
- Thailand
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Idiopathic Normal Pressure Hydrocephalus (INPH), Gait Disorders, Neurologic
Unsteady Gait in Older People May be a Common and Treatable Neurological Disease Associated With Increased Mortality
We live in an aging population and a third of the older population has a gait disorder that may cause institutionalization, and increased mortality.
- Conditions
- Idiopathic Normal Pressure Hydrocephalus (INPH), Gait Disorders, Neurologic, Gait Disorders in Old Age
- Trial name
- VESPR2 (NCT07137403)
- Where
- Sweden
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University
Hydrocephalus, Idiopathic Normal Pressure Hydrocephalus
Clinical Outcome in Patients With INPH
The aim of this study is to determine the clinical spectrum and natural progression of idiopathic normal pressure hydrocephalus （iNPH ) and related disorders in a prospective single center study, identify digital, imaging and…
- Conditions
- Hydrocephalus, Idiopathic Normal Pressure Hydrocephalus, CSF, Glympathic System
- Trial name
- NCT06428734
- Testing
- hydrocephalus group, normal group
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Educational, Simulation
Simulation Efficacy in Neurosurgical Education
This study aims to investigate the efficacy of simulation in neurosurgical training.
- Conditions
- Educational, Simulation, Hydrocephalus, Intraventricular Hemorrhage
- Trial name
- SENSE (NCT02988154)
- Testing
- Simulation training, ''See one, do one'' approach
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Intracranial Hemorrhages, Acute Ischemic Stroke
AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction
- Trial name
- AI-REACT (NCT06018545)
- Testing
- Ground truthing, Reading
- Where
- 4 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Spina Bifida With Hydrocephalus
Impact of a Standing Program in a Child With Spina Bifida: A Case Report
The purpose of this case study is to investigate a child with MMC who has significant knee and hip flexion contractures to answer the following research questions: 1) Is a home standing program effective in reducing hip and knee…
- Trial name
- NCT05251740
- Testing
- Altimate Medical EasyStand Bantam
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of St. Augustine for Health Sciences
Hydrocephalus, Normal Pressure, Ventriculomegaly, Cerebral
Volumetrics and Proteomics in Shunted Normal Pressure Hydrocephalus
Idiopathic normal pressure hydrocephalus (=iNPH) is a condition with disturbed circulation of cerebrospinal fluid (=CSF) causing symptoms such as balance and gait disorders, urinary incontinence and cognitive impairment in…
- Conditions
- Hydrocephalus, Normal Pressure, Ventriculomegaly, Cerebral, Shunt; Complications, Hydrocephalus Acquired
- Trial name
- LiNPH (NCT04785560)
- Testing
- Initial shunt setting post-operatively of the Certas Plus shunt valve.
- Where
- Sweden
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Normal Pressure Hydrocephalus
The Brain Structure and Neural Network Changing the Before and After Ventriculo-peritoneal Shunting in the Normal Pressure Hydrocephalus Patients
With the advent of the aging society, dementia becomes the focus of common people. As for the neurodegeneration dementia, no disease modifying treatments have been discovered.
- Trial name
- NCT03092804
- Testing
- ventriculo-peritoneal shunting
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cerebral Ventriculomegaly
Prospective Follow-up of a Multicentric Cohort of Children With Prenatal Discovery of Mild Isolated Cerebral Ventriculomegaly. Evaluation at 2 and 5 Years.
Isolated uni or bilateral mild cerebral ventriculomegaly represents the most frequent "minor" cerebral anomalies discovered by antenatal echography.
- Trial name
- NCT00421772
- Where
- 2 sites in France
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Hydrocephalus
Caregiver Burden and Anxiety in Mothers of Children With Hydrocephalus
This study is being conducted in randomized controlled trial design to determine the effect of the education given to the mothers of children with hydrocephalus on caregiver burden and anxiety levels.
- Trial name
- NCT05544279
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Hydrocephalus
Formative Usability Assessment of Wireless Thermal Anisotropy Devices
Measurements of shunt flow will be performed non-invasively. This study will generate usability data via observed tasks and comprehension questions to enable future device design improvements.
- Trial name
- NCT06040697
- Testing
- Thermal Anisotropy
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Rhaeos, Inc.
Hydrocephalus, Parkinson Disease
Characterization of Dynamic Stability in Normal Pressure Hydrocephalus and Parkinson's Disease
This study aims to characterize dynamic stability disorders in two conditions mainly affecting the elderly and with similar walking deficits: hydrocephalus at normal pressure and Parkinson's disease, to provide the most relevant…
- Conditions
- Hydrocephalus, Parkinson Disease, Walking, Difficulty, Movement Disorders
- Trial name
- HPGAIT (NCT05998473)
- Testing
- Dynamic stability measurement
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Normal Pressure Hydrocephalus
White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)
Idiopathic Normal Pressure Hydrocephalus (iNPH) is a progressive condition of the elderly that results in severe disability. iNPH can dramatically respond to Cerebral spinal fluid(CSF)-shunting where excess ventricular fluid is…
- Trial name
- OWN-NPH (NCT07103681)
- Testing
- Ventriculoperitoneal Shunt (VP), Brain and Skin Biopsy, MRI Brain
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Idiopathic Normal Pressure Hydrocephalus
Gait Pattern and Experienced Global Change After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus
Part 1 Patients with idiopathic Normal Pressure Hydrocephalus (iNPH) have variable disabilities regarding gait, balance, cognition and continence.
- Trial name
- NCT04795089
- Testing
- Shunt surgery
- Where
- Sweden
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Idiopathic Normal Pressure Hydrocephalus (INPH)
Walking Pattern Characteristics in Normal Pressure Hydrocephalus
20 patients who are diagnosed with NPH receive a set of 5 wearable gyroscopes (IMUs, ZurichMove sensors) for a period of 3 days for measurement and characterization of their walking in an ambulatory setting.
- Trial name
- NPH wearables (NCT04702035)
- Testing
- Characterization of walking pattern characteristics in an ambulatory setting using wearable IMUs (ZurichMOVE sensors)
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hemorrhage, Premature Infants
NIRS Monitoring in Premature Infants
This study uses frequency domain near-infrared spectroscopy coupled with diffuse correlation spectroscopy (FDNIRS-DCS) technology for monitoring cerebral blood flow (CBF) and cerebral oxygen metabolism (CMRO2) at the bedside for…
- Conditions
- Hemorrhage, Premature Infants, Newborn, Hydrocephalus
- Trial name
- NCT02601339
- Testing
- ETV/CPC
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Parkinson Disease, Multiple System Atrophy
A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies
This will be an observational study looking at clinical and biomarker characteristics in patients with Parkinson's Disease (PD), Multiple System Atrophy (MSA), Rapid Eye Movement Sleep Behavior Disorder (RBD), Normal Pressure…
- Conditions
- Parkinson Disease, Multiple System Atrophy, Rapid Eye Movement Sleep Behavior Disorder, Normal Pressure Hydrocephalus
- Trial name
- NCT04020198
- Testing
- Biomarker assay
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stony Brook University