Clinical trials: Hydroxyapatite
Tooth Hypersensitivity
Hypersensitivity and Color Changes of Bleached Teeth Using Different Remineralizing Agents
The aim of this in vivo study is to evaluate the post-bleaching enamel hypersensitivity and the possible color changes following the application of arginine and nano-hydroxyapatite remineralizing solutions after enamel bleaching…
- Trial name
- NCT04875000
- Testing
- Remineralizing agent I application, Remineralizing agent II application, Remineralizing agent III application
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Periodontitis
Evaluation of Advanced PRF Combined With Nano-crystalline Hydroxyapatite for Management of Grade II Furcation Defects
this study is to evaluate the use of advanced platelet rich fibrin (A-PRF) + nano-crystalline hydroxyapatite bone substitute combined with open flap debridement (OPD) versus open flap debridement alone in the management of…
- Trial name
- NCT03804086
- Testing
- Advanced PRF (A-PRF) + nano-crystalline hydroxyapatite bone substitute combined with open flap debridement, Open flap debridement
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hadeer Ashraf Hassan Roushdy
Gingival Inflammation and Loss the Orthodontic Mini-screws
Strontium-Hydroxyapatite Coated Mini-Screws: Antibacterial Effect and Stability
This randomized controlled clinical trial aims to evaluate the antibacterial efficacy and stability of strontium-incorporated hydroxyapatite (Sr-HA) coated orthodontic mini-screws (OMSs) used for maxillary canine retraction.
- Trial name
- NCT07105969
- Testing
- Strontium Incorporated Hydroxyapatite [Sr-HA] coated mini-screws purchased from Dentarum company
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Caries
The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children.
The aim of this RCT was to verify the caries preventive efficacy of toothpastes containing biomimetic hydroxyapatite (H.A.) complex in children compared to traditional fluoridated toothpastes.
- Trial name
- NCT04906291
- Testing
- Toothpaste use
- Where
- Italy
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Caries,Dental
Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries
Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone.
- Trial name
- NCT04147091
- Testing
- ApaCare & Repair
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Tooth Decay, Hydroxyapatite
Hydroxyapatite-toothpaste and Enamel Caries in the Primary Dentition
This multicenter, non-inferiority trial randomized, double-blind, active controlled parallel group study evaluates the hypothesis that the home regular use of a toothpaste containing microcrystalline hydroxylapatite (HAP) (test…
- Conditions
- Tooth Decay, Hydroxyapatite, Tooth Demineralization, Tooth Diseases
- Trial name
- ECIPDEN17 (NCT03553966)
- Testing
- Prophylactic, Cleaning teeth, Restorative dentistry
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Kurt Wolff GmbH & Co. KG
Chitosan, Nano-hydroxyapatite Hydrogel
Chitosan Nano-hydroxyapatite Hydrogel in Non-Surgical Treatment of Intrabony Defect
The aim of this study was to evaluate the clinical effect of Chitosan with nano-hydroxyapatite hydrogel in the treatment of periodontal intrabony defects.
- Conditions
- Chitosan, Nano-hydroxyapatite Hydrogel, Intrabony Defect
- Trial name
- NCT06373757
- Testing
- Nano-HAP/Chitosan hydrogel
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- October 6 University
Dental Implant Failed
Immediate Implant Placement With Provisionalization Using Different Bone Grafts as a Space Filling Material in the Maxillary Esthetic Zone
compare autogenous bone graft, xenograft and nanohydroxyapatite in immediate implant w placement in maxillary esthetic zone with provisionalization
- Trial name
- NCT03741036
- Testing
- Autogenous bone graft as space filling in immidiate implant placment, Deprotinized bovien as space filling in immidate implant placement, Nano-hydroxiapatite alloplast in immidiate implant placement
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mohamed tarek mohamed youssif omar
Teeth Color, Teeth Staining
A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control
To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for…
- Trial name
- NCT07214038
- Testing
- toothpaste
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Marginal Integrity of Hydroxyapatite Nanofiber Reinforced Flowable Composite
Evaluation of Marginal Integrity of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional Resin-Based Flowable Composite in Initially Demineralized Pits and Fissure: A One Year, Randomized Clinical Trial
This study will be conducted to evaluate the Marginal integrity of Hydroxyapatite Nanofiber reinforced flowable composite compared to a conventional resin-based flowable composite during management of initial carious lesion in…
- Trial name
- NCT03242291
- Testing
- Conventional resin-based flowable composite, Hydroxyapatite Nanofiber reinforced flowable composite
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wrinkles
Injectable Filler for Facial Soft Tissue Augmentation
The purpose of this study is to assess the safety and performance of Hydroxytite in all subjects who have received sub dermal or deep dermal injections.
- Trial name
- NCT02218788
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Panaxia Ltd
Osseointegration Failure of Dental Implant
Effectiveness of Hydroxyapatite Reinforced Chitosan Hydrogel in Modulation of Osseointegration
Dental implant treatments have now become indispensable in clinical dental practice. The survival rate exceeds 90%; Modern oral implantology uses different devices, in terms of size, shape, length, thickness and composition, from…
- Trial name
- NCT06758440
- Testing
- chitosan
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minia University
Dentin Sensitivity
Effect of Nano-hydroxyapatite and LASER on Dentin Hypersensitivity
The aim of this study was to evaluate the effect of nanohydroxyapatite associated with low potency laser therapy in eliminating or reducing dentin hypersensitivity in a randomized placebo-controlled clinical trial.
- Trial name
- NCT03637426
- Testing
- Laser, nano-hydroxyapatite, Laser + nano-hydroxyapatite
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Randomized Clinical Trial
Clinical and Radiographic Outcome of Regeneration in Immature Permanent Human Teeth Using a New Scaffold
This study aimed to evaluate clinical and radiographic outcome of regeneration in immature permanent human teeth using two different types of scaffolds: 1. Collagen-hydroxyapatite scaffold (Osteon III collagen) after blood clot.
- Trial name
- NCT06812351
- Testing
- Osteon III collagen, Blood clot
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Dentinal Hypersensitivity
Treatment of Tooth Sensitivity With the Use of Biorepair Toothpaste
The purpose of this clinical study is to evaluate the effect of desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals in reducing or controlling DH after 8 weeks of treatment
- Trial name
- NCT04091256
- Testing
- Single arm clinical study
- Where
- Saudi Arabia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Qassim University
Tooth Extraction
Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
After the removal of a tooth, a bone graft is often placed in the socket to try to keep the volume of bone that was there when the tooth was present so that the bone does not "shrink".
- Trial name
- NCT07154693
- Testing
- Combination 70% FDBA and 30% DFDBA, OsteoGen Plug
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Intrabony Periodontal Defect
Efficacy of Titanium Granules in the Treatment of Periodontal Intrabony Defects
The ideal goal of the periodontal treatment is not only to prevent the progression of the disease, but also the regeneration and reconstruction of lost tissues.
- Trial name
- NCT04932161
- Testing
- Titanium Granules, Hydroxyapatite
- Where
- India
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Caries, Dental
Remineralization Effects of Hydroxyapatite Toothpaste
The objective of this in situ clinical study is to determine whether a toothpaste containing hydroxyapatite microclusters is as effective as a fluoridated kid's toothpaste in promoting remineralization of early caries lesions and…
- Trial name
- NCT03681340
- Testing
- Hydroxyapatite toothpaste, Fluoridated toothpaste
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Joachim Enax
Alveolar Bone Loss
Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation
This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic…
- Trial name
- SYNBIO (NCT03077867)
- Testing
- sinus floor augmentation with bone graft
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Open Fracture of Foot
In Vivo Clinical Trial of Porous Starch - Hydroxyapatite Composite Biomaterials for Bone Regeneration
Biodegradable scaffold is an accepted and commercialized medical alternative choice for bone regeneration. In this project we will used our new invention, porous starch- hydroxyapatite composite, for in vivo clinical trial.
- Trial name
- NCT02910232
- Testing
- bone void filler
- Where
- Thailand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University