Clinical trials: Hydroxyapatite
Atrophied Posterior Maxillary Ridge
Open Sinus Lift Technique With Simultaneous Implantation Using Platelet Rich Fibrin (PRF) Versus Nano-crystalline Hydroxyapatite
Evaluation of bone quantity in open sinus lift technique with space maintaining using platelet rich fibrin (PRF) as sole augmentation material versus nano crystalline hydroxyapatite with simultaneous placing of implants.
- Trial name
- NCT02577289
- Testing
- Evaluation of bone quantity in open sinus lift technique with simultaneous implantation ( Nano crystalline hydroxyapatite), Evaluation of bone quantity in open sinus lift technique with simultaneous implantation (PRF)
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Femoral Neck Fractures
Osseointegration of Hydroxyapatite-coated Femoral Stems in Femoral Neck Fractures Over 80 Years
This study aimes to prove that osseointegration of hydroxyapatite coated stem is possible for patients over 80 years with femoral neck fracture, without the risks of cemented stems.
- Trial name
- NCT04773145
- Testing
- Hemiarthroplasty with hydroaxyapatite coated stem
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Maxillary Sinus Lift
Sinus Lift With Hydroxyapatite Nano Particles Versus Tenting Technique
twenty recruited patients indicated for sinus augmentation and immediate implant placement will be divided into two groups (10 in each of the two groups), to compare bone formation and implant stability after shneiderian membrane…
- Trial name
- NCT03177876
- Testing
- sinus lift implant placement Hydroxyapatite Nano particles, sinus lift implant placement tenting
- Volunteers
- 20 people
- Sponsor
- Cairo University
Caries, Dental
Remineralization Effects of Hydroxyapatite Toothpaste
The objective of this in situ clinical study is to determine whether a toothpaste containing hydroxyapatite microclusters is as effective as a fluoridated kid's toothpaste in promoting remineralization of early caries lesions and…
- Trial name
- NCT03681340
- Testing
- Hydroxyapatite toothpaste, Fluoridated toothpaste
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Joachim Enax
Bone Resorption
Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Alendronate in the Preservation of the Tooth Socket
Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in teh research project, which TEMPhas more TEMPthan 20 teeth, are over 18 years old and…
- Trial name
- NCT03980847
- Testing
- Alendronate 20 mg, Nanocrystal hydroxyapatite
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Bone Loss
Freeze-dried Bovine Hydroxyapatite/Secretome Composite for Bone Defects
This clinical trial aims to investigate the efficacy of freeze-dried bovine hydroxyapatite/secretome composite application for the management of long bone defects and other bone healing disorders in the lower extremities.
- Trial name
- NCT04980261
- Testing
- ORIF + autograft, ORIF + FD BHA/Secretome
- Where
- Indonesia
- Volunteers
- 32 people
- Sponsor
- Dr. Soetomo General Hospital
Open Fracture of Foot
In Vivo Clinical Trial of Porous Starch - Hydroxyapatite Composite Biomaterials for Bone Regeneration
Biodegradable scaffold is an accepted and commercialized medical alternative choice for bone regeneration. In this project we will used our new invention, porous starch- hydroxyapatite composite, for in vivo clinical trial.
- Trial name
- NCT02910232
- Testing
- bone void filler
- Where
- Thailand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Periodontal Intrabony Defects, Bone Regeneration
Comparison of Effects of Eggshell Derived Nano Hydroxyapatite and Hydroxyapatite in Management of Periodontal Intrabony Defects
The aim of the study is to evaluate osseous regenerative efficacy of eggshell derived nanohydroxyapatite in comparison with hydroxyapatite The test group includes patients with intrabony defects where flap surgery will be…
- Trial name
- NCT07160101
- Testing
- Eggshell derived nano hydroxyapatite, Hydroxyapatite
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Dr R Viswa Chandra
Bone Loss
Evaluation, the Histomorphometric Study of Nanocrystalline Hydroxyapatite (Nano Bone) Wif Lovastatin in the Preservation of the Tooth Socket
Twenty patients referring to periodontics department of Boroujerd Azad university of dentistry after obtaining consent to participate in the research project, which have more than 20 teeth, are over 18 years old and require…
- Trial name
- NCT03981601
- Testing
- Lovastatin 40 MG, without drug with Bone graft
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Arthropathy of Hip
Study Comparing BoneMaster Hydroxyapatite Coating With Plasma-sprayed Hydroxyapatite Coating on Acetabular Cups
The randomised controlled trial will be carried out on patients that require a total hip replacement (THR) to reduce pain and restore their function.
- Trial name
- NCT00859976
- Testing
- BoneMaster coated acetabular shell., Plasma Coated Acetabular Shell
- Where
- United Kingdom
- Volunteers
- 167 people
- Sponsor
- Zimmer Biomet
Orbital Implants
A Modified Orbital Implantation Technique in Enucleation
To assess the functional and cosmetic outcomes of enucleation with rectus end-to-end suturing surgical technique in hydroxyapatite orbital implants
- Trial name
- NCT01207713
- Volunteers
- 45 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
TEETH EXTRACTION
Ridge Preservation Using a Ossix™ Bone vs Bio-Oss® Collagen
This randomized, parallel design, controlled study will assess the histologic healing of this Ossix™ Bone in humans and compare it to a Bio-Oss® Collagen that is well researched. Subjects will be enrolled into 2 groups.
- Trial name
- NCT04338516
- Testing
- Ossix™ Bone, Bio-Oss® Collagen
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Datum Dental LTD
Hypersensitivity Dentin
Effectiveness of the Use of Desensitizing Dentifrices Based on Nanocrystals of Hydroxyapatite / 5% Potassium Nitrate / 1450ppm Sodium Monofluorophosphate and Potassium Nitrate 5% / 1426ppm Sodium Floride in the Treatment of Dentine Hypersensitivity. Test Randomized Clinical
Background: Currently, periodontal treatment, both surgical and non-surgical, leaves sequelae in the vast majority of patients, dentine hypersensitivity (HSD) is one of the most important.
- Trial name
- NCT04156152
- Testing
- DEENSIBILIZING TOOTHPASTE BASED ON NANOCRISTALS OF HYDROXIAPATITA / 5% POTASSIC NITRATE / SODIUM MONOFluORPHOSPHATE 1450 PARTS PER MILLION, 5% POTASSIC NITRATE / SODIUM FLUORIDE 1426 PARTS PER MILLION TOOTHPASTE
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Bone Atrophy, Edentulism
Pilot Study on the Effectiveness of a Flexible Hydroxyapatite-Based Composite for Jaw Bone Regeneration
Following a review of the scientific literature, it was found that there are no clinical studies but only in vitro and in vivo studies, which show promising results in terms of bone formation and integration.
- Conditions
- Bone Atrophy, Edentulism, Bone Regeneration
- Trial name
- Flexi2024 (NCT06552715)
- Testing
- Placement of resorbable HAp-based composite
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Bologna
Alveolar Ridge Preservation
Alveolar Ridge Preservation Procedures
Tooth loss is accompanied by different patterns of bone loss. Up to 50% loss of alveolar crestal bone width will likely occur 1 year after tooth loss, especially in the anterior maxilla.
- Trial name
- NCT05419778
- Testing
- Osteogen plug®, MInerOss®
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Dentin Sensitivity
Use of Biomaterials as Desensitizer Agents
Aim: to investigate the clinical effectiveness over 12 weeks of three different biomaterials, nano-hydroxyapatite based, in the therapy of the dental sensitivity.
- Trial name
- NCT02770573
- Testing
- Cavex Bite&White ExSense, Kuraray Teethmate™ Desensitizer, Ghimas Dentin Desensitizer
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Università degli Studi di Sassari
Cerebral Decompression Injury, Cranioplasty
Controlled Study in Cranioplasty Reconstruction
Multicenter, prospective, comparative, observational study with regular follow-up visits. The project's aim is long-term follow-up of patients affected by large and complex craniolacuniae treated, in standard clinical practice…
- Trial name
- NCT01641523
- Testing
- CustomBone Service
- Volunteers
- 91 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Dental Caries, Hydroxyapatite
Study of People's Profile Living in France Who Could be Interested in the Use of a Nanohydroxyapatite Toothpaste
Nano-hydroxyapatite is an interesting candidate to be a substitute for fluor in toothpastes or a complement to fluorides in order to prevent caries.
- Trial name
- NCT05234060
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Gout, Chondrocalcinosis
CRYSTALILLE Cohort: Getting the Whole Picture of Crystal-related Arthropathies
The objective of this research is to collect data to create an observatory of microcrystalline rheumatism (gout and calcium-crystal rheumatism) in patients treated at the Groupement des Hôpitaux de l'Institut Catholique de Lille…
- Conditions
- Gout, Chondrocalcinosis, Hydroxyapatite
- Trial name
- CRYSTALILLE (NCT04695028)
- Testing
- Data collection
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Lille Catholic University
Alveolar Bone Loss
Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation
This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic…
- Trial name
- SYNBIO (NCT03077867)
- Testing
- sinus floor augmentation with bone graft
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy