Clinical trials: Hydroxyapatite
Dentin Hypersensitivity, Fluoride
Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs. Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin Hypersensitivity
compare the effectiveness of Eggshell derived nano-Hydroxyapatite with and without fluoride and conventional fluoride containing tooth paste versus conventional desensitizing fluoride containing tooth paste on dentinal tubule…
- Conditions
- Dentin Hypersensitivity, Fluoride, Nano-hydroxy Apatite
- Trial name
- NCT06493500
- Testing
- Eggshell derived Nano-hydroxyapatite (n-HAp) with a Fluoride containing toothpaste, Eggshell derived Nano-hydroxyapatite (n-HAp) without a Fluoride containing toothpaste
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Volunteers, Discoloration of Teeth
Evaluation of Tooth Sensitivity and Whitening Effects of Different Content Teeth Whitening Agents
The goal of this clinical study is to evaluate the success of different whitening agents in whitening teeth in healthy volunteers aged 18-50. Also, patients' tooth sensitivity will be assessed after application.
- Conditions
- Healthy Volunteers, Discoloration of Teeth, Bleaching Sensitivity
- Trial name
- NCT06855940
- Testing
- Bleaching Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Betül Tokat
Molar Incisor Hypomineralization
Remineralization of Molar Incisor Hypomineralization (MIH) With a Hydroxyapatite Toothpaste
This study tests the remineralization of donor teeth (donorMIH) in situ in participants using 10% hydroxyapatite (HAP) toothpaste and sodium fluoride toothpaste.
- Trial name
- NCT05485662
- Testing
- Hydroxyapatite toothpaste, Sodium Fluoride Toothpaste
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Alveolar Bone Loss
Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation
This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic…
- Trial name
- SYNBIO (NCT03077867)
- Testing
- sinus floor augmentation with bone graft
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Cleft
Assessment of Nanocrystalline Hydroxyapatite Versus Autogenous Bone Grafts : A Comparative Clinical Study in Alveolar Cleft Grafting
This work aims to evaluate Nanocrystalline Hydroxyapatite versus Autogenous bone grafts in alveolar cleft grafting
- Trial name
- NCT04693559
- Testing
- secondary alveolar bone graft, harvesting of the autogenous bone graft, Nanocrystalline Hydroxyapatite
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intrabony Periodontal Defect
Regeneration of Intrabony Defects With Nano Hydroxyapatite Graft, and Periosteum as Barrier Membrane Under Magnification
The prospective study is a interventional study to evaluate and compare the effectiveness of periosteal pedicle as grafting technique and egg shell derived nano hydroxyapatite as regenerative graft material for regeneration of…
- Trial name
- NCT04195295
- Testing
- Regeneration of Intrabony Defects with Nano Hydroxyapatite Graft, Derived from Egg Shell along with Periosteum as Barrier Membrane, Regeneration of intrabony defects using Egg shell derived nano hydroxyapatite (EnHA) as regenerative graft material, Open flap debridement procedure in intrabony defects.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Effects of the Elements
Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions
recruited patients with periapical lesions will be divided into three groups and surgically treated with three types of bone graft (hydroxyappatite, nanohydroxyappatite and PRF WITH NANOHYDROXTAPPATITE) and then evaluated for…
- Trial name
- NCT05100615
- Testing
- surgery
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Minia University
Osseointegration Failure of Dental Implant
Effectiveness of Hydroxyapatite Reinforced Chitosan Hydrogel in Modulation of Osseointegration
Dental implant treatments have now become indispensable in clinical dental practice. The survival rate exceeds 90%; Modern oral implantology uses different devices, in terms of size, shape, length, thickness and composition, from…
- Trial name
- NCT06758440
- Testing
- chitosan
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minia University
Volume Loss to Dorsum of Hands
A Single-Center Investigator-Initiated Evaluator-Bilateral-Comparison Pilot Study of Injectable Calcium Hydroxylapatite With and Without Triamcinolone Acetate for the Treatment of Volume Loss to Dorsum Areas of the Hands
This will be a single-center, investigator-initiated, double-blinded, randomized, bilateral-comparison pilot study of injectable Calcium hydroxylapatite with and without Triamcinolone acetate for the treatment of volume loss to…
- Trial name
- NCT02454088
- Testing
- Calcium Hydroxylapatite and Triamcinolone acetate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Gingival Inflammation and Loss the Orthodontic Mini-screws
Strontium-Hydroxyapatite Coated Mini-Screws: Antibacterial Effect and Stability
This randomized controlled clinical trial aims to evaluate the antibacterial efficacy and stability of strontium-incorporated hydroxyapatite (Sr-HA) coated orthodontic mini-screws (OMSs) used for maxillary canine retraction.
- Trial name
- NCT07105969
- Testing
- Strontium Incorporated Hydroxyapatite [Sr-HA] coated mini-screws purchased from Dentarum company
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Open Fracture of Foot
In Vivo Clinical Trial of Porous Starch - Hydroxyapatite Composite Biomaterials for Bone Regeneration
Biodegradable scaffold is an accepted and commercialized medical alternative choice for bone regeneration. In this project we will used our new invention, porous starch- hydroxyapatite composite, for in vivo clinical trial.
- Trial name
- NCT02910232
- Testing
- bone void filler
- Where
- Thailand
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Periodontal Diseases, Hypersensitivity Dentin
Clinical Efficacy of Vector Paro With Hydroxyapatite in the Supportive Therapy of Periodontitis
Enamel is the most calcified tissue in the body and is composed of 92-96% by organic substances in particular hydroxyapatite. Hydroxyapatite nanoparticles are similar to the morphology and structure of tooth enamel apatite…
- Conditions
- Periodontal Diseases, Hypersensitivity Dentin, Hydroxyapatite
- Trial name
- PAROXY (NCT07482280)
- Testing
- hydroxyapatite debridment, ultrasonic debridment
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Wrinkles
Injectable Filler for Facial Soft Tissue Augmentation
The purpose of this study is to assess the safety and performance of Hydroxytite in all subjects who have received sub dermal or deep dermal injections.
- Trial name
- NCT02218788
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Panaxia Ltd
Caries
The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children.
The aim of this RCT was to verify the caries preventive efficacy of toothpastes containing biomimetic hydroxyapatite (H.A.) complex in children compared to traditional fluoridated toothpastes.
- Trial name
- NCT04906291
- Testing
- Toothpaste use
- Where
- Italy
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Intrabony Periodontal Defect
Efficacy of Titanium Granules in the Treatment of Periodontal Intrabony Defects
The ideal goal of the periodontal treatment is not only to prevent the progression of the disease, but also the regeneration and reconstruction of lost tissues.
- Trial name
- NCT04932161
- Testing
- Titanium Granules, Hydroxyapatite
- Where
- India
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Dental Caries Class II
A Clinical Assessment of Glass Carbomer Cement
This study will evaluate the clinical performance of glass carbomer cement restorations in restoring proximal lesions in primary molars compared to that of resin modified glass ionomer cement and composite resin restorations.
- Trial name
- NCT03030690
- Testing
- Glass Carbomer Cement, Composite Resin, Resin Modified Glass Ionomer Cement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Implant Failed
Immediate Implant Placement With Provisionalization Using Different Bone Grafts as a Space Filling Material in the Maxillary Esthetic Zone
compare autogenous bone graft, xenograft and nanohydroxyapatite in immediate implant w placement in maxillary esthetic zone with provisionalization
- Trial name
- NCT03741036
- Testing
- Autogenous bone graft as space filling in immidiate implant placment, Deprotinized bovien as space filling in immidate implant placement, Nano-hydroxiapatite alloplast in immidiate implant placement
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mohamed tarek mohamed youssif omar
Dentinal Hypersensitivity
Treatment of Tooth Sensitivity With the Use of Biorepair Toothpaste
The purpose of this clinical study is to evaluate the effect of desensitizing toothpaste containing zinc-carbonate hydroxyapatite nanocrystals in reducing or controlling DH after 8 weeks of treatment
- Trial name
- NCT04091256
- Testing
- Single arm clinical study
- Where
- Saudi Arabia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Qassim University
Dental Caries
Effects of a Hydroxyapatite-based Mouth Gel on Calcium Content of Plaque
The aim of this pilot study is to analyze if a hydroxyapatite-containing mouth gel has an influence on the calcium content of plaque.
- Trial name
- NCT03956992
- Testing
- Mouth gel
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dr. Joachim Enax
Primary Total Hip Arthroplasty
Clinical Observation Study of the Hydroxylapatite-coated SLPLUS™MIA Hip Shaft
Summary from initial protocol Goal: Validation of the HA (hydroxylapatite) coated SLPLUS ™ MIA stem within an observation study Study design: prospective, multicenter, observational, noncomparative study Study population: 300…
- Trial name
- SL-Plus HA MIA (NCT04036071)
- Testing
- Total Hip Arthroplasty
- Where
- 3 sites in Austria
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew Orthopaedics AG