Clinical trials: Hyperbilirubinemia
Cholangitis Acute, Biliary Tract Diseases
Antimicrobial Resistance in Acute Cholangitis
This study prospectively explores antimicrobial resistance in patients with acute cholangitis undergoing ERCP procedures. By analyzing patient profiles, microbial cultures, and treatment outcomes, the current study seeks to…
- Conditions
- Cholangitis Acute, Biliary Tract Diseases, Jaundice; Malignant, Jaundice, Obstructive
- Trial name
- ARISE (NCT06197984)
- Testing
- ERCP
- Where
- Romania
- Volunteers
- 1,435 people
- Sponsor
- Emergency County Hospital Pius Brinzeu; Timisoara, Romania
Distal Bile Duct Obstruction
Covered vs Uncovered Metal Stents for Palliative Biliary Decompression in Inoperable Malignant Distal Bile Duct Obstruction
The purpose of this study is to compare the rate of long-term stent failure, defined as need for repeat biliary intervention following placement of C-SEMS vs U-SEMS for palliation of inoperable malignant distal bile duct…
- Trial name
- NCT01905384
- Testing
- Covered Self-expanding metal biliary stents (C-SEMS), Uncovered Self-expanding metal biliary stents (U-SEMS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Vanderbilt University Medical Center
Bile Duct Neoplasms, Jaundice, Obstructive
A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles
The goal of this observational study is to detect the methylation characteristics of cfDNA in the bile and plasma of patients with bile duct stricture.
- Conditions
- Bile Duct Neoplasms, Jaundice, Obstructive, Bile Duct Diseases
- Trial name
- NCT06115655
- Testing
- cfDNA methylation detection
- Where
- China
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Obstructive Jaundice, Cholangitis
Cholangioscopic Assessment of Occluded Biliary Stent and Role of Biliary Radiofrequency Ablation
Primary Objective: To document state-of- the-art multi-modality management of occluded biliary SEMS aiming to minimize number of reinterventions while providing symptom relief without procedure-related serious adverse events.
- Trial name
- NCT03133026
- Testing
- Single operator cholangioscopy, Endoscopic biliary RFA
- Where
- India
- Volunteers
- 4 people
- Sponsor
- Asian Institute of Gastroenterology, India
Hyperbilirubinemia, Neonatal
Transcutaneous Bilirubin Levels From Covered Skin
The aim of this study was to evaluate the levels of total serum bilirubin and transcutaneous bilirubin in newborns, measured in both covered and exposed areas, before phototherapy, 24th hour of phototherapy and 8 hours after…
- Trial name
- NCT06105879
- Testing
- covered or open skin
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara Training and Research Hospital
Obstructive Jaundice
Outcome of Carbon Dioxide Versus Air Insufflations During Endoscopic Retrograde Cholangiopancreatography (ERCP)
To assess the safety and efficacy of CO2 insufflations during ERCP 1. Primary objective: To assess the patient's symptoms, abdominal pain and abdominal distension post procedure (ERCP) in the study group. 2.
- Trial name
- NCT01321203
- Where
- India
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Neonatal Jaundice
Comparing the Effect of Vimala Massage Versus Hydrotherapy on the Clinical Outcomes of Neonatal Hyperbilirubinemia
The aim of this study is to evaluate the effect of Vimala massage versus hydrotherapy on the clinical outcomes of neonatal hyperbilirubinemia.
- Trial name
- NCT06595368
- Testing
- Vimala massage, Hydrotherapy
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Obstructive Jaundice, Pancreatic Head Cancer
Impact of Intraoperative PTCD Catheter Retention Versus Removal on Postoperative Short-term Outcomes After Pancreaticoduodenectomy in Obstructive Jaundice
Pancreaticoduodenectomy (PD) is a complex surgical procedure commonly performed for tumors of the pancreatic head and periampullary region.
- Conditions
- Obstructive Jaundice, Pancreatic Head Cancer, Periampullary Neoplasms, Biliary Tract Neoplasms
- Trial name
- NCT07532759
- Testing
- PTCD Catheter Removal, PTCD Catheter Retention
- Volunteers
- 100 people
- Sponsor
- Xu'an Wang
Newborn Jaundice
Influence of Breast Milk Smell on Newborns Bilirubin Level, Duration of Time Phototherapy and Comfort in Newborns Receiving Phototherapyv
ABSTRACT Purpose: This research was done for the purpose of determining the impact of breast milk smell administered to term infants hospitalized in neonatal intensive care units (NICU) due to physiological jaundice on their…
- Trial name
- NCT05167474
- Testing
- breast milk smell
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Neonatal Jaundice, Neonatal Hyperbilirubinemia
Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Population in Botswana
This project aims to test a novel smartphone application, Picterus, which provides a cheaper, patient-friendly, and more readily means of neonatal jaundice detection.
- Trial name
- BILIAPPBOT (NCT06399146)
- Testing
- Picterus App
- Where
- Botswana
- Volunteers
- 150 people
- Sponsor
- Hillerod Hospital, Denmark
Failure in Endovascular Therapy, Splanchnic Aneurysm
Salvage Surgeries for Splanchnic Artery Aneurysms After Failed Endovascular Therapies: Cases Series
A retrospective review was performed for consecutive patients (from 2019 to 2021) who underwent salvage surgeries following failed endovascular therapies for splanchnic artery aneurysms in a tertiary referral center.
- Conditions
- Failure in Endovascular Therapy, Splanchnic Aneurysm, Mass Effect, Surgery
- Trial name
- NCT05727956
- Testing
- Aneurysmectomy
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- China Medical University Hospital
Neonatal Jaundice, Phototherapy Complication
Continuous Versus Intermittent Phototherapy in Treatment of Neonatal Jaundice
One of the most common diseases in the neonatal period is indirect hyperbilirubinemia (IHB). After phototherapy was discovered accidentally in 1958, it has been used as the most effective treatment method for IHD for more than 60…
- Trial name
- NCT06386731
- Testing
- Intermittent Phototherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Indirect Hyperbilirubinemia
Efficacy of Bifidobacterium Animalis Subsp. Lactis in the Treatment of Indirect Hyperbilirubinemia in Term Neonates
This study aims to evaluate the effectiveness of adjunctive oral Bifidobacterium animalis subsp. lactis in term neonates with indirect hyperbilirubinemia receiving phototherapy.
- Trial name
- NCT07773012
- Testing
- Bifidobacterium animalis subsp. lactis, Standard Phototherapy
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Hyperbilirubinemia, Neonatal
Role of Fenofibrate in Indirect Neonatal Hyperbilirubinemia: a Randomized Control Trial
Fenofibrate accelerates bilirubin conjugation and excretion, decreasing the side effects of prolonged unconjugated hyperbilirubinemia in neonates.
- Trial name
- NCT04868019
- Testing
- Fenofibrate Capsules
- Volunteers
- 60 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Jaundice, Obstructive
Biliary Cannulation During Endoscopic Retrograde Cholangiopancreatography: Precut Versus Conventional Cannulation
Endoscopic sphincterotomy is now an established method for removal of common bile duct calculi and treatment of papillary stenosis, the sump syndrome and certain cases of ampullary carcinoma.
- Trial name
- ERCP (NCT02477228)
- Testing
- conventional ERCP, Precut ERCP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Hepatocellular Carcinoma, Bilirubinemia
Safety of Transarterial Chemoembolization (TACE) in the Setting of an Elevated Bilirubin
The aim of this study is to evaluate the safety of selective transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) in the setting of an elevated total bilirubin, but relatively normal direct bilirubin.
- Trial name
- NCT03259581
- Testing
- Transarterial chemoembolization
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Minnesota
Jaundice, Neonatal
Associations of Nighttime Light Exposure During Pregnancy With Neonatal Jaundice：a Multi-centre Prospective Study in China
Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.
- Trial name
- jaundice (NCT03805165)
- Where
- China
- Volunteers
- 2,977 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Obstructive Jaundice, Pancreatic Cancer
Endoscopic Ultrasound-guided Biliary Drainage for Malignant Biliary Obstruction After Failed ERCP
In this study the investigators retrospectively report outcomes of direct transluminal EUS-BD in a series of patients with malignant biliary obstruction after failed ERCP as the experience of a single Italian center
- Trial name
- (EUS-BD) (NCT03510754)
- Testing
- Eus guided biliary drainage
- Volunteers
- 36 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Education
The Effect of Neonatal Jaundice Education on Mothers' Knowledge Level and the Incidence of Jaundice Development
This study was a randomised controlled trial conducted to determine the effect of the training given to mothers who gave birth by caesarean section in the obstetrics and gynaecology service clinic of Sultanbeyli State Hospital on…
- Trial name
- NCT07187622
- Testing
- examine the impact of education
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Okan University
Neonatal Hyperbilirubinemia
Neonatal Hyperbilirubinaemia in the Democratic Republic of Congo
Neonatal hyperbilirubinaemia (NH) is common among healthy neonates and normally resolves within a week. Untreated pathological hyperbilirubinaemia, however, can result in long-term neurological sequelae, which compromise…
- Trial name
- NCT03880591
- Where
- Democratic Republic of the Congo
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Oxford