Clinical trials: Hyperkalemia
Hyperkalemia
Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns
The purpose of this study is to find out whether there is a correlation (link) between the level of potassium in blood samples drawn from a vein and those drawn from a heel stick in infants scheduled for elective surgery.
- Trial name
- PS (NCT01349218)
- Testing
- Blood sample drawn from a vein, Blood sample drawn from a heel stick
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hyperkalemia
Assessment of Hyperkalemia's Illness and Treatment Burden in Chronic Kidney Disease and Heart Failure Patients: HK Registry Pilot Study
Overall study aim of this study is to analyse descriptive statistics of Patient-Reported Outcome（PROs） which will be used in the Hyperkalemia（HK） registry study in hyperkalemia patients with Chronic Kidney Disease（CKD） or Heart…
- Trial name
- HKRegistrypilo (NCT04466969)
- Where
- 5 sites in Japan
- Volunteers
- 146 people
- Sponsor
- AstraZeneca
Hyperkalemia
ZS Ph2/3 Dose-response Study in Japan
To assess efficacy of 5 g three times daily (TID) and 10 g TID ZS versus placebo in Japanese patients with hyperkalemia (serum potassium [S-K] ≥ 5.1 mmol/L and ≤ 6.5 mmol/L).
- Trial name
- NCT03127644
- Testing
- Sodium Zirconium Cyclosilicate (ZS) 5g, Sodium Zirconium Cyclosilicate (ZS) 10g
- Where
- 25 sites in Japan
- Volunteers
- 103 people
- Sponsor
- AstraZeneca
Hyperkalaemia
Safety of Oral Resin for Treatment of Hyperkalemia in Chinese Patients With Renal Insufficiency
It is a multicenter, prospective, non-interventional cohort study, in order to evaluate the safety of oral resin for treatment of hyperkalemia in Chinese patients with renal insufficiency.
- Trial name
- SCRUTINIZE (NCT05462119)
- Where
- 16 sites in China
- Volunteers
- 887 people
- Sponsor
- AstraZeneca
Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5
Healthy Diet Rich in Potassium to Chronic Kidney Disease With Sodium Zirconium Cyclosilicate: A Feasibility Study
This is a descriptive single arm open-label interventional trial lasting 6 weeks aiming to test if a low protein healthy K-rich diet with fruits, vegetables, whole grains, and nuts with concomitant use of new potassium binder…
- Conditions
- Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Hyperkalemia
- Trial name
- HELPFUL (NCT04207203)
- Testing
- sodium zirconium cyclosilicate and healthy diet
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Karolinska Institutet
Hyperkalaemia
AI-Enabled ECG Stratification and Timing of Potassium-Lowering Therapy in Patients With Hyperkalemia: A Target Trial Emulation Study
Hyperkalemia is a common and potentially life-threatening electrolyte disorder, yet there is limited evidence guiding the optimal timing of potassium-lowering therapy in routine clinical practice.
- Trial name
- AIDE-K (NCT07307729)
- Testing
- Timely treatment, Delayed treatment
- Volunteers
- 5,000 people
- Sponsor
- National Defense Medical Center, Taiwan
Hyperkalemia Elevated Plasma K+ Cardiovascular Disease (CVD)
Retrospective Study to Describe Prevalence of Hyperkalemia in Russian Population Based on Large Laboratory Network (HEKATE)
This is a cross-sectional retrospective study of laboratory records of patients who take electrolytes blood tests containing the data of the serum potassium level.
- Trial name
- NCT03657875
- Where
- Russia
- Volunteers
- 53,940 people
- Sponsor
- AstraZeneca
Hyperkalaemia, Heart Failure with Reduced Ejection Fraction
Hyperkalaemia and Its Impact on Therapy with RAASi
Renin-angiotensin-aldosterone system inhibitors (RAASi) have transformed prognosis of patients with heart failure with reduced ejection fraction, diabetic nephropathy and chronic kidney disease.
- Conditions
- Hyperkalaemia, Heart Failure with Reduced Ejection Fraction, Left Ventricular Systolic Dysfunction
- Trial name
- REVIEW (NCT04249648)
- Where
- United Kingdom
- Volunteers
- 651 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Hyperkalemia
Effect of Patiromer in Children Under 12 Years of Age With High Blood Potassium Levels
A study to evaluate the pharmacodynamic effects, safety, and tolerability of patiromer in children under 12 years of age with hyperkalaemia.
- Trial name
- EMERALD2 (NCT05766839)
- Testing
- Patiromer
- Where
- 37 sites in United States, Australia and 13 more
- Volunteers
- 36 people
- Sponsor
- Vifor Pharma, Inc.
Hemodialysis Complication
Retrospective Survey of Hyperkalemia in Hemodialysis
This study aim to describe hyperkalemia clinical burden and investigate the risk factors associated with the burden on HD facility level.
- Trial name
- Visualize-HD (NCT05020717)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
Chronic Kidney Disease, Hyperkalemia
A Multicenter Study to Evaluate the Nutritional Suitability of Renastart
A multicenter, open label, uncontrolled study to evaluate the acceptability, tolerability, and nutritional suitability of a medical food (Renastart, Vitaflo International Ltd) specially formulated to meet the unique nutritional…
- Trial name
- Renastart (NCT02825784)
- Testing
- Renastart
- Where
- 3 sites in Germany
- Volunteers
- 12 people
- Sponsor
- Vitaflo International, Ltd
Hyperkalemia, Chronic Kidney Disease (Stages 4 and 5)
Safety of a Healthy Plant-based Diet With Higher Potassium Content, Compared to a Healthy Plant-based Diet With Limited Potassium Content in Patients With Chronic Kidney Disease: A Pilot Study
For many years, people with moderate to advanced chronic kidney disease (CKD) have been advised to limit their intake of potassium, a mineral found in many foods such as fruit, vegetables, legumes, whole grains, and nuts.
- Trial name
- SAFE-K (NCT07494266)
- Testing
- Healthy plant-based diet (healthy-PBD), Potassium-restricted plant-based diet
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Hyperkalemia
Patiromer for the Management of Hyperkalemia in Subjects Receiving RAASi Medications for the Treatment of Heart Failure (DIAMOND)
The purpose of this study is to assess the effects of patiromer compared with placebo on serum K+ in HF patients.
- Trial name
- DIAMOND (NCT03888066)
- Testing
- Patiromer
- Where
- 415 sites in United States, Argentina and 19 more
- Volunteers
- 1,195 people
- Sponsor
- Vifor Pharma, Inc.
Hemodialysis
Dietary Phosphorus Load and Postprandial Serum Phosphate in HD Patients
This study is to investigate the acute postprandial effect of a modified versus standard low phosphorus diet on serum phosphate, potassium and intact parathyroid levels in prevalent hemodialysis (HD) patients
- Trial name
- NCT04845724
- Testing
- Standard Diet, Modified Diet
- Volunteers
- 8 people
- Sponsor
- University College Cork
Hyperkalemia
Clinical Potassium Pilot Study
In this pilot study, 30 prevalent hemodialysis patients will undergo three regular hemodialysis sessions during which various potassium assessments will be performed.
- Trial name
- NCT04251468
- Testing
- GEPII, Ion-selective electrodes
- Where
- Austria
- Volunteers
- 33 people
- Sponsor
- Medical University of Graz
Hyperkalemia
IMpact of hyPeRkalaemia on thErapy With Renin angiotenSin aldoSterone System Inhibitors
There are limited data regarding the burden of hyperkalaemia in patients attending emergency departments (ED) or who are hospitalised (excluding those already receiving dialysis).
- Trial name
- IMPRESS (NCT04510792)
- Testing
- No intervention
- Where
- United Kingdom
- Sponsor
- Portsmouth Hospitals NHS Trust
Hyperkalemia, Hypokalemia
Description of the Clinical Outcomes of Hospitalized Patients With Heart Failure With Different Serum Potassium Levels
China National Heart Failure Registration Study (CN-HF) is a nationwide, hospital-based, multicentre, prospective registry study sponsored by Ministry of Science and Technology of the People's Republic of China.
- Conditions
- Hyperkalemia, Hypokalemia, Heart Failure
- Trial name
- SPLENDID (NCT05184998)
- Where
- China
- Volunteers
- 6,950 people
- Sponsor
- AstraZeneca
Hyperkalemia
Tracking Treatment Pathways in Adult Patients With Hyperkalemia.
This study aims to increase the understanding of Hyperkalemia (HK) management, treatment patterns, and the treatment decision-making process for the management of patients with HK over a period of up to 12 months.
- Trial name
- TRACK (NCT05408039)
- Where
- 74 sites in United States, Germany and 3 more
- Volunteers
- 1,331 people
- Sponsor
- AstraZeneca
Sodium Zirconium Cyclosilicate, Hyperkalemia
Sodium Zirconium Cyclosilicate Lowers Hyperkalemia After Parathyroidectomy
Sodium zirconium cyclosilicate (SZC) has been demonstrated for its serum potassium-lowering efficacy and safety in hyperkalemia hemodialysis patients. However, the effects of SZC during the perioperative period remained unknown.
- Conditions
- Sodium Zirconium Cyclosilicate, Hyperkalemia, Hyperparathyroidism, Secondary
- Trial name
- SZC (NCT05382988)
- Testing
- Sodium zirconium cyclosilicate
- Volunteers
- 62 people
- Sponsor
- Guangdong Provincial People's Hospital
Chronic Kidney Disease 5D, Hyperkalemia
Nurse-Led Nutritional Education for Moroccan Dialysis Patients
Why was this study done? Many dialysis centers in Morocco lack dietitians to provide proper, individualized dietary support to patients.
- Conditions
- Chronic Kidney Disease 5D, Hyperkalemia, Hemodialysis
- Trial name
- NCT07277530
- Testing
- Nutritional Education Intervention
- Where
- Morocco
- Volunteers
- 30 people
- Sponsor
- HASSAN 1st university