Clinical trials: Hypertension, Pregnancy Induced
Pre-Eclampsia
L-Arginine and Antioxidant Vitamins During Pregnancy to Reduce Preeclampsia
This study is intended to assess the efficacy of L-arginine supplementation with antioxidant vitamins delivered in a medical food in reducing the incidence of preeclampsia in a high-risk population.
- Trial name
- L-Arg (NCT00469846)
- Testing
- L-arginine supplementation in a medical food, Vitamin C and E supplementation in a medical food
- Where
- 2 sites in United States, Mexico
- Volunteers
- 585 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Apnea, Obstructive Sleep, Pregnancy Complications
Sleep Apnea Syndrome in Obese Women During Pregnancy
Excess weight or obesity is associated with an increased risk of health disorders: high blood pressure, diabetes, cardiovascular risks, dyslipidemia and sleep apneas.
- Conditions
- Apnea, Obstructive Sleep, Pregnancy Complications, Pre-Eclampsia, Obesity
- Trial name
- NCT03509805
- Testing
- polysomnography
- Where
- France
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Preeclampsia Severe
Transorbital Ultrasound of Optic Nerve Sheath Diameter Between Healthy Pregnant Women and Those With Severe Preeclampsia.
The neurological alterations associated with preeclampsia depend on cerebral autoregulation, a theory that outlines the mechanisms by which the nervous system controls cerebral perfusion.
- Trial name
- NCT05594056
- Testing
- Transorbital ultrasound of the optic nerve sheet
- Where
- Panama
- Volunteers
- 100 people
- Sponsor
- Saint Thomas Hospital, Panama
Gestational Diabetes, Gestational Hypertension
Preventing Obstetric Complications With Dietary Intervention
The goal of this study is to learn whether access to healthy and fresh food, health coaching, and nutrition support intervention can reduce adverse birth outcomes in pregnant women.
- Conditions
- Gestational Diabetes, Gestational Hypertension, High Risk Pregnancy, Preeclampsia
- Trial name
- PLATE (NCT06320054)
- Testing
- Maternal Health Management Program
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
High Risk Pregnancy
Impact of the NO-donor Pentaerythrithyltetrantrate on Perinatal Outcome in High-risk Pregnancies
Pregnancies resulting in IUGR and also in preeclampsia are strongly associated with typical underlying placental pathology revealing small placentas and maldevelopment of the decidual blood vessels, suggesting under-perfusion…
- Trial name
- NCT01355822
- Testing
- PETN
- Where
- Germany
- Volunteers
- 111 people
- Sponsor
- University of Jena
Preeclampsia
sFlt-1:PlGF Ratio in Diagnosing Superimposed Preeclampsia
Preeclampsia: associated with poor placentation, incomplete uteroplacental spiral arteries remodeling. Result: ischemia, re-perfusion injury, oxidative stress.
- Trial name
- NCT03441711
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Tennessee
Simulation Training, Midwifery Students Education
The Effectiveness of Combined Virtual and Clinical Simulation in Midwifery Students
Objective: To evaluate the effectiveness of combined virtual and high-fidelity clinical simulation compared with virtual simulation only on theoretical knowledge and clinical judgment in undergraduate midwifery students managing…
- Conditions
- Simulation Training, Midwifery Students Education, Clinical Competence, Education, Health
- Trial name
- NCT06630143
- Testing
- Combined Virtual and Clinical Simulation, virtual simulation
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- Universidad de los Andes, Chile
Preeclampsia, Preterm Delivery
Ambient Air Pollution, Preeclampsia, and Preterm Delivery
An epidemiologic study of pregnant women in western Washington to measure the relationships between exposure to air pollutants and risks of preeclampsia and preterm delivery.
- Trial name
- NCT00468663
- Volunteers
- 4,200 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Preeclampsia
EV Based Platform for Monitoring Therapeutics Response During Pregnancy (ARISE)
The goal of this prospective observational cohort study of pregnant people at-risk of preeclampsia receiving aspirin as part of clinical care or a planned randomized controlled trial of 81mg vs.
- Trial name
- NCT06249178
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Ohio State University
Preeclampsia
Racial Differences: Nitric Oxide(NO) and Endothelin-1(ET-1) in Preeclampsia (PreE)
The goal of this study is to examine the activation of markers of endothelial and cardiovascular dysfunctions, from women with high-risk pregnancies.
- Trial name
- NCT00653809
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Mississippi Medical Center
Preeclampsia, Periodontal Disease
Association of Periodontitis and Preeclampsia During Pregnancy
Infections affecting the mother during pregnancy may produce alterations in the normal cytokine and hormone-regulated gestation, which could result in preeclampsia, preterm labor, premature rupture of membranes, and preterm…
- Trial name
- NCT00855504
- Where
- India
- Volunteers
- 528 people
- Sponsor
- Maulana Azad Medical College
Breastfeeding, Breastfeeding Initiation
Birth & Breastfeeding Support Study
The goal of this observational study is to learn about the effects of birth practices such as cesarean section and vacuum assisted birth and diseases such as gestational diabetes and preeclampsia on exclusive breastfeeding.
- Conditions
- Breastfeeding, Breastfeeding Initiation, Breastfeeding Duration, Birth
- Trial name
- BABSS (NCT06844019)
- Where
- Denmark
- Volunteers
- 1,628 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Preeclampsia Postpartum
Aspirin for Postpartum Patients With Preeclampsia
The purpose of this research study is to evaluate the effect of low-dose aspirin on recovery from severe preeclampsia (a high blood pressure disorder of pregnancy) among women who have given birth.
- Trial name
- ASAPP (NCT05924971)
- Testing
- Aspirin 81Mg Ec Tab
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- MemorialCare Health System
Pre-Eclampsia, Pregnancy Complications
Preeclampsia Sequential Screening Using Angiogenic Factors During First Trimester of Pregnancy
Preeclampsia (PE) affects from 2 to 8% of pregnant women. Recent studies show that prevention is the best strategy to improve perinatal outcomes.
- Trial name
- CRISP (NCT04767438)
- Testing
- Pregnant women
- Volunteers
- 6,560 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Pregnancy Related, Hypertension in Pregnancy
Deep Breathing Techniques (Pranayama) in Pregnancy
Slow deep breathing actives the vagal nerve and leads to a natural reduction in physiological parameters such as blood pressure, heart rate and digestion. The effects of these techniques have not been assessed in pregnancy.
- Conditions
- Pregnancy Related, Hypertension in Pregnancy, Blood Pressure
- Trial name
- NCT05341921
- Testing
- Alternate Nostril Breathing, Bhramari Breathing, Sheetali Breathing
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Preeclampsia, Pregnancy Complications
Berlin-Brandenburg Pregnancy Cohort
This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications.
- Conditions
- Preeclampsia, Pregnancy Complications, Diabetes Mellitus in Pregnancy
- Trial name
- BBPC (NCT03313024)
- Where
- Germany
- Volunteers
- 1,580 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Eclampsia
Point-of-care Ultrasound Abnormalities in Eclampsia
Preeclampsia (PE) and eclampsia remain leading causes of maternal morbidity and mortality, in both high-, low-and-middle-income countries.
- Trial name
- NCT05678062
- Testing
- Point-of-care ultrasound
- Where
- South Africa
- Volunteers
- 70 people
- Sponsor
- University of Cape Town
Preeclampsia
LMWH to Prevent Preeclampsia and Fetal Growth Restriction
The objective of this trial will be to determine whether prophylactic low-molecular weight heparin therapy in pregnant women with the heterozygous Factor V Leiden and G20210A prothrombin gene mutations thrombophilia and a history…
- Trial name
- NCT00260520
- Testing
- Dalteparin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florence
Pre-Eclampsia
Low Dose Aspirin for Prevention of Early Pregnancy Loss
Preeclampsia is a pregnancy-specific, multisystem disorder affecting 3% to 8% of pregnancies and remains a significant cause of maternal and neonatal morbidity and mortality worldwide.
- Trial name
- NCT06261203
- Testing
- Aspirin
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Egymedicalpedia
Postpartum Infection
Trends in Pregnancy Outcomes Beyond Twenty Weeks Gestational Age in Assisted Reproductive Technology Conceived Pregnancies in British Columbia
Examining outcomes beyond 20 weeks gestational age in pregnancies conceived by ART compared to spontaneously conceived pregnancies 1.
- Trial name
- NCT06726603
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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