Clinical trials: Hypertension, Resistant
Hypertension
Milk Proteins, Ambulatory Blood Pressure and Vascular Function
Epidemiological studies demonstrated an inverse associations between cardiovascular events and milk and dairy product consumption.
- Trial name
- NCT02090842
- Testing
- Ca-caseinate, Maltodextrin, Whey protein isolate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hypertension, Resistant to Conventional Therapy
MANP in African Americans With Hypertension
Evaluate the cardiovascular properties of MANP in AA with Hypertension
- Trial name
- MANP-2 (NCT04542681)
- Testing
- MANP - 1st Cycle, MANP - 2nd Cycle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Hypertriglyceridemia
Effects of Omega-3 Fatty Acids on Markers of Inflammation
The major purpose of this study is to examine the effect of two sources of dietary omega-3 fatty acids, each given at two doses, on potential health benefits related to cardiovascular disease prevention.
- Conditions
- Obesity, Hypertriglyceridemia, Insulin Resistance, Hypertension
- Trial name
- NCT01129050
- Testing
- Fish Oil, Flaxseed Oil
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cardiovascular Risk Factor, Metabolic Syndrome
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk
This cross-over study investigates health effects of dietary intake of whole walnuts towards cardiovascular risk factors in adults under low cardiovascular risk.
- Conditions
- Cardiovascular Risk Factor, Metabolic Syndrome, Hypertension
- Trial name
- FitALA (NCT03227497)
- Testing
- Whole Walnuts
- Where
- Serbia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Hypertension, Hyperglycemia
Effect of Dietary Fiber on Metabolic Syndrome, Gastrointestinal Function, Mood and Sleep Quality in Obese People
Metabolic syndrome includes hypertension(high blood pressure), hyperglycemia(high blood suger), dyslipidemia(abnormal blood lipid level) and obesity.
- Conditions
- Hypertension, Hyperglycemia, Dyslipidemia, Obesity
- Trial name
- NCT06626867
- Testing
- Dietary Fiber Supplementation
- Where
- Taiwan
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Chien-Wen Hou
Hyperlipidemia, Diabetes Mellitus
Baseline Physiology Studies in Carriers of Gene Variant X Conferring Major Risk of CVD-prone Metabolic Disorders
The purpose of the present study is to conduct a thorough and relevant physiology study of carriers and non-carriers of the gene variant X in order to determine the effect of the genetic variant on various metabolic parameters.
- Conditions
- Hyperlipidemia, Diabetes Mellitus, Metabolic Syndrome, Arterial Hypertension
- Trial name
- NCT01571609
- Testing
- first phase insulin secretion (FPIR), Hyperinsulinemic euglycemic clamp (HEC), glucose tracer, and palmitate tracer
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension, Obesity
Renal Response to Lower Body Negative Pressure in Pre-hypertensive States
The purpose of this study is to determine whether in pre-hypertensive and hypertensive states such as white coat hypertension, obesity related hypertension or resistant hypertension, renal function is more sensitive to…
- Conditions
- Hypertension, Obesity, White Coat Hypertension, Resistant Hypertension
- Trial name
- NCT01734096
- Testing
- Lower body negative pressure (LBNP), Candesartan cilexetil
- Where
- 2 sites in Switzerland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- PD Dr. Grégoire Wuerzner
Metabolic Syndrome X, Insulin Resistance
Physical Inactivity and Insulin Resistance in Skeletal Muscle.
The purpose of this study is to determine how a decline in physical activity acutely leads to a decrease in insulin sensitivity in skeletal muscle.
- Conditions
- Metabolic Syndrome X, Insulin Resistance, Hypertension, Hypercholesterolemia
- Trial name
- NCT00536211
- Testing
- Exercise, Metformin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Abdominal Obesity, Metabolic Syndrome
WAVE Study- Walking and Aging in VErona Study
Monocentric unblinded two parallel-group randomized controlled trial to evaluate the effect of diet with or without Nordic Walking on weight loss, physical performance and cardiovascular risk factors in overweight and obese…
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Disability Physical, Sarcopenic Obesity
- Trial name
- WAVE (NCT03212391)
- Testing
- Diet, Walking, Nordic Walking
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Hypertension
Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow
The overall objective of this proposal is to examine the contribution of changes in total body fat, enhancement in insulin-mediated vasodilatation and enhancement in endothelium-derived nitric oxide production to the improvements…
- Trial name
- NCT00018304
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Abdominal Obesity, Metabolic Syndrome
Aldosterone, Microvascular Function and Salt-sensitivity
Currently, the incidence of obesity and obesity-related disorders is reaching epidemic proportions, which entails an increasing burden for health care systems.
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Sodium-sensitivity, Insulin Resistance
- Trial name
- NCT02068781
- Testing
- Low-sodium diet, High-sodium diet
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Vascular Resistance, Hypertension
Resveratrol and Cardiovascular Health in the Elderly
Background: Resveratrol is a compound found in the skin of red grapes. It is being tested to see if it can have positive effects on human health.
- Trial name
- NCT01842399
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Hypertension, Metabolic Syndrome
Diva - The Effects Of 12 Weeks Of Treatment With High Dose Valsartan (320 Mg) To Amlodipine On Endothelial Function In Hypertensive Subjects With The Metabolic Syndrome
A STUDY ON WHETHER AN ANTIHYPERTENSIVE MEDICATION PREVENTS DAMAGE TO WALLS OF VEINS IN FEMALE PATIENTS WITH THE METABOLIC SYNDROME (OVERWEIGHT AND OTHER DISORDERS).
- Trial name
- NCT00241150
- Testing
- VALSARTAN
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novartis
Cardiovascular Diseases, Vascular Diseases
Influence of Age, Weight and Ethnic Background on Blood Pressure
Hypertension, also known as high blood pressure, is a chronic medical condition, in which the blood pressure is elevated. This is a common condition, which can lead to severe complications such as cardiovascular disease, heart…
- Conditions
- Cardiovascular Diseases, Vascular Diseases, Hypertension
- Trial name
- AWE (NCT03014791)
- Testing
- Brief lifestyle/medical history questionnaire, Anthropometric measures, Blood pressure and arterial stiffness
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Dyslipidemia, Insulin Resistance Syndrome
Prescription of Step Counts for Targeted Changes in Body Composition and Cardiometabolic Risk in Overweight/Obese Adults
The prevalence of overweight and obesity remains epidemic in the United States, with some of the highest rates seen in older adults.
- Conditions
- Dyslipidemia, Insulin Resistance Syndrome, Hypertension, Inflammation Chronic
- Trial name
- NCT07221279
- Testing
- Step counts for predictable changes in body weight/compositon and cardiometabolic risk
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Diabetes, Hypertension
Survey of Thai-Muslim Health Status
The purpose of this study was to determine the prevalence and risk factors of diabetes, hypertension, hyperlipidemia among Thai muslim population aged 35-75 years.
- Conditions
- Diabetes, Hypertension, Hyperlipidemia
- Trial name
- NCT00701454
- Testing
- No intervention
- Where
- Thailand
- Volunteers
- 1,488 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hypertension, Diabetes
Free Fatty Acids-Induced Hypertension in Obese Subjects (Aim #2)
The purpose of this study is to see if salsalate, an Nuclear factor-kappaB (NF-κB) mediated inflammation inhibitor, or carvedilol, an α- and β-blocker, will protect against free fatty acid induced hypertension, insulin…
- Trial name
- FFAADA (NCT02406586)
- Testing
- Salsalate, Carvedilol, Intralipid 20%
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypertension
Post-Exercise Hypotension in Elderly Hypertensive Men
The purpose of this study is to compare the effects of two exercise protocols on post-exercise blood pressure versus a control group in elderly hypertensive men.
- Trial name
- HPE (NCT02415582)
- Testing
- Aerobic exercise, Combined exercises, Control
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Metabolic Syndrome X, Obesity
The Metabolic Effects of Different Weight Loss Diets
Current estimates suggest that 65% of American adults are overweight or obese. Excess body weight has been associated with an increased risk of a number of metabolic abnormalities, including high blood sugar, high blood pressure…
- Conditions
- Metabolic Syndrome X, Obesity, Insulin Resistance, Hypertension
- Trial name
- NCT00422630
- Testing
- The DASH diet, The low glycemic Index Diet, Reduced calorie American Diet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rockefeller University