Clinical trials: Hypertension Emergency
Headache, Acute, Focal Neurologic Disease
Digital Ocular Fundus Photography in the Emergency Department: A New Application for Telemedicine?
The purpose of this study is to determine if non-dilated retinal photography in the emergency room improves the diagnosis of papilledema (optic nerve swelling) in patients with neurologic disease compared to direct ophthalmoscopy.
- Conditions
- Headache, Acute, Focal Neurologic Disease, Severely Elevated Blood Pressure, Acute Visual Loss
- Trial name
- NCT00873613
- Testing
- Use of Non-dilated retinal photography
- Where
- United States
- Volunteers
- 705 people
- Sponsor
- Emory University
Abdominal Compartment Syndrome
Relation Between Intrabdominal Pressure and Collapsibility Index of Inferior Vena Cava Before and After Fluid Therapy
This study assess the relation between intra abdominal pressure and collapsibility index of inferior vena cava in emergency bedside ultrasonography before and after fluid therapy.
- Trial name
- NCT01553422
- Testing
- Fluid therapy (Saline Normal)
- Where
- Iran
- Volunteers
- 82 people
- Sponsor
- Isfahan University of Medical Sciences
Hypertensive Emergency
a Study Evaluating the Safety and Efficacy of Clevidipine for Patients Who With Hypertensive Emergency and Sub-emergency
A Multicentre, Randomized, Double-blind, Parallel Design Phase III Study to Evaluate the efficacy and safety of QLG2071 Versus Cleviprex® in the Treatment of Hypertensive Emergency and Sub-emergency
- Trial name
- NCT05922436
- Testing
- QLG2071, Cleviprex®
- Volunteers
- 378 people
- Sponsor
- Qilu Pharmaceutical (Hainan) Co., Ltd.
Malignant Hypertension
Determinants of Malignant Hypertension Onset and Related Target Organ Damages: the HAMA Biobank
The HAMA bank is an initiative aimed at collecting, preparing, and storing biological samples from patients treated for malignant hypertension and included in the HAMA cohort.
- Trial name
- HAMABANK (NCT06629363)
- Testing
- biobank
- Where
- 11 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier de PAU
Hypertension
Reach Out: Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health Systems
This study evaluates a health theory based mobile health behavioral intervention to reduce blood pressure (BP) among hypertensive patients evaluated in a community Emergency Department (ED) setting.
- Trial name
- ReachOut ED (NCT03422718)
- Testing
- Healthy Behavior Texts, No healthy behavior texts, BP Monitoring Daily Via Text Messaging
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Michigan
Hypertensive Emergency
Safety and Efficacy Study of Clevidipine Butyrate Injection in Hypertensive Emergencies
The purpose of this study was to determine the efficacy and safety of clevidipine for treating Hypertensive emergencies（defined as systolic blood pressure >180 mmHg and/or diastolic blood pressure >120 mmHg, accompanied by acute…
- Trial name
- NCT04670809
- Testing
- Clevidipine Butyrate Injection, Ncardipine Hydrochloride Injection
- Where
- 2 sites in China
- Volunteers
- 262 people
- Sponsor
- Nanjing Yoko Biomedical Co., Ltd.
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Hypertension
Emergency Department Home Blood Pressure Monitoring and BpTRU Study
The purpose of this study is to evaluate the Congruence of Emergency Department (ED) Attendings' Predictions of Hypertension with Results of Home Blood Pressure Monitoring.
- Trial name
- NCT02217059
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Hypertensive Emergency, Papilledema
Optic Nerve Sheath Diameter in Hypertensive Emergency
This prospective observational study investigates the potential of point-of-care ultrasonography of the optic nerve sheath diameter (ONSD) to rule out papilledema in patients with suspected hypertensive emergency.
- Conditions
- Hypertensive Emergency, Papilledema, Hypertension
- Trial name
- OpticUS (NCT06286696)
- Testing
- Optic Nerve Sheath Diameter
- Volunteers
- 375 people
- Sponsor
- Leiden University Medical Center
Hypertensive Urgency
Effect of Pursed-Lip Breathing on Blood Pressure and Heart Rate
Hypertensive urgency (HT urgency) is an alarm sign of uncontrolled hypertension. It can be aggravated by nonadherent to medication and psychosocial stress.
- Trial name
- NCT04572672
- Testing
- Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Khon Kaen University
Digestive Diseases, Adrenal Insufficiency
Adrenal Insufficiency in Critical Emergencies in Digestive Diseases
Observational study about the incidence of relative adrenal insufficiency in patients with cirrhosis and acute variceal bleeding; in patients with acute peptic gastrointestinal bleeding and without liver disease; and in patients…
- Conditions
- Digestive Diseases, Adrenal Insufficiency, Gastrointestinal Bleeding, Variceal Bleeding
- Trial name
- NCT00562445
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Postpartum Hypertension Study
The purpose of this study is to assess which blood pressure medication (intravenous labetalol or oral nifedipine) works better in treating severely elevated blood pressure in women who have just delivered a baby.
- Conditions
- Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Pregnancy-Induced Hypertension in Postpartum, Hypertensive Emergency
- Trial name
- NCT05139238
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Blood Pressure, Hypertension
Blood Pressure in the Emergency Department
This is a cohort study based on a large sample (> 600 000) of emergency department (ED) visits from two university hospital EDs.
- Conditions
- Blood Pressure, Hypertension, Emergencies
- Trial name
- PREBPED (NCT03954119)
- Volunteers
- 300,272 people
- Sponsor
- Karolinska Institutet
Suspected Placental Dysfunction, Ruled Out, Pregnancy Complications
Interest of sFlt1/PlGF Ratio at Obstetric Emergencies
In patients with suspected placental vascular disease who do not require hospitalization, the use of the sFlt-1 (Soluble FMS like tyrosin-kinase-1)/PlGF (Placental Growth Factor)/ assay can most likely help teams to define the…
- Conditions
- Suspected Placental Dysfunction, Ruled Out, Pregnancy Complications, Pre-Eclampsia
- Trial name
- AngioCHIC (NCT04170660)
- Testing
- Diagnostic test
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Hypertension, Blood Pressure
Monitoring Blood Pressure at Home and Pharmacy Telehealth
The overall goal of this project is to determine if measuring blood pressure at home and staying in contact with a team of pharmacists and physicians to manage participants' blood pressure is useful.
- Trial name
- REMAP-BP (NCT07623291)
- Testing
- Remote Blood Pressure Monitoring + Telehealth
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- University of Alabama at Birmingham
Systemic Inflammatory Response Syndrome (SIRS), Sepsis
IMproved PREdiction of Severe Sepsis in the Emergency Department
The purposes of this study is to determine whether Heparin Binding Protein (HBP) can be used as a marker of severe sepsis (including septic shock) in patients presenting to the emergency department with suspected infection.
- Conditions
- Systemic Inflammatory Response Syndrome (SIRS), Sepsis, Severe Sepsis, Septic Shock
- Trial name
- IMPRESSED (NCT01392508)
- Where
- 5 sites in United States, Sweden
- Volunteers
- 759 people
- Sponsor
- Axis Shield Diagnostics Ltd
Medication Adherence, Hypertension
Pharmaceutical Care in Emergency Department
The purpose of this study is to evaluate the effectiveness of pharmaceutical care, compared to usual care, in patient discharge in an emergency department in patients with hypertension and/or diabetes mellitus type 2.
- Conditions
- Medication Adherence, Hypertension, Diabetes Mellitus
- Trial name
- AMPaRAR (NCT01978925)
- Testing
- Pharmaceutical care
- Where
- Brazil
- Volunteers
- 380 people
- Sponsor
- Hospital Moinhos de Vento
Hypertension, Adolescent Behavior
Youth-Led Intervention to Improve Blood Pressure
The proposed study will develop, test, and collect implementation data on a youth-led hypertension (HTN) education intervention, which will act as an electronic tool to guide youth through learning and then teaching adults on how…
- Conditions
- Hypertension, Adolescent Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05029687
- Testing
- Youth-Led Hypertension Education Digital Intervention
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Stroke, Ischemic Attack
An Intervention for Elderly in Emergency Services
-Can a scheme based on inter geriatricians visiting nurse consultants and reduce negative impacts on the health of elderly over 70 years ?
- Conditions
- Stroke, Ischemic Attack, Diabetes Mellitus, Hypertension
- Trial name
- NCT01706133
- Testing
- Factors associated with the use of emergency departments
- Where
- Mexico
- Volunteers
- 1,400 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Hypertension, High Blood Pressure
Pre-clinical Cardiac Dysfunction Among Asymptomatic Hypertensive Patients
This project will evaluate the clinical and cost effectiveness of a novel, multidisciplinary approach to identify and treat pre-clinical cardiac dysfunction (PCCD) in asymptomatic hypertensive patients identified in a single…
- Conditions
- Hypertension, High Blood Pressure, Ventricular Hypertrophy, Diastolic Dysfunction
- Trial name
- NCT00689819
- Testing
- Exercise, Weight Loss, Low Sodium Diet
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Wayne State University