Clinical trials: Hypertensive Disorder of Pregnancy
Hypertension, Pregnancy-Induced, Hypertension in Pregnancy
Meditation as Complementary Treatment for Chronic Hypertension in Pregnancy
Pregnancy relates to arterial hypertension; it is an aggravating factor for pre-existing chronic arterial hypertension or a trigger for preeclampsia in normotensive women.
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension in Pregnancy, Hypertension
- Trial name
- NCT03873194
- Testing
- Meditation, conventional treatment
- Where
- Brazil
- Volunteers
- 47 people
- Sponsor
- University of Sao Paulo General Hospital
Hypertension ,Pregnancy, Diabetes During Pregnancy
Impact of Exercise Prescription on Obstetric and Neonatal Outcomes
The aim of this study is to assess the impact of structured physical activity with smartwatch remote monitoring on glycemic control, blood pressure control, obstetric complications and neonatal outcomes in women with GDM, chronic…
- Conditions
- Hypertension ,Pregnancy, Diabetes During Pregnancy, Obesity (BMI>30)
- Trial name
- NCT07678944
- Testing
- Physical activity plan, Women who received information but did not engaged in a physical activity routine
- Where
- Portugal
- Volunteers
- 310 people
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Preeclampsia
Different Schemes of Magnesium Sulfate for Preeclampsia
Eclampsia is an obstetric emergency capable of prophylaxis. To prevent and control seizures, there is no doubt that the magnesium sulfate (MgSO4) is the ideal drug. However, there are still questions regarding its use and dose.
- Trial name
- MGSO4 (NCT02396030)
- Testing
- Magnesium sulfate 50% - 1g/h, Magnesium sulfate 50% - 2g/h
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Pregnant Woman
Pilot Trial of Hibiscus Drink During Pregnancy (PTHDDP)
The goal of this phase I pilot clinical trial is to evaluate the acceptability, tolerability and effect on blood pressure and biomarkers of Hibiscus sabdariffa drink in pregnant women in the second trimester of pregnancy.
- Trial name
- PTHDDP (NCT07175597)
- Testing
- Hibiscus sabdariffa drink
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Victor Eduardo Alcantar Rodríguez
Hypertension in Pregnancy, Hypertension
Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
The diagnosis of hypertensive disease during pregnancy is predicated on strict blood pressure thresholds: 140/90 on at least two occasions measured four hours apart for both gestational hypertension and preeclampsia.
- Conditions
- Hypertension in Pregnancy, Hypertension, Obesity
- Trial name
- NCT06466161
- Testing
- Upper Arm Cylindrical Blood Pressure Cuff, Forearm Conical Blood Pressure Cuff
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Northwestern University
Hypertension, CKD - Chronic Kidney Disease
The Effects of Dietary Nitrate in Patients With Hypertensive Kidney Injury
The study aims to study the effects of diatery nitrate in patients with hypertension and hypertensive kidney injury. The study is a randomized, placebo-controlled, double-blinded crossover trial.
- Trial name
- DINO-CKD (NCT07290842)
- Testing
- Beetroot Juice - Active
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Gødstrup Hospital
Blood Pressure
Evaluation of Target Organs Impairment on Patients Suffering From High Blood Pressure
Evaluation of target organs impairment on patients suffering from high blood pressure without known cardio vascular or renal disease, stratified on blood pressure control.
- Trial name
- PREVENTA (NCT00925470)
- Where
- 369 sites in France
- Volunteers
- 1,200 people
- Sponsor
- AstraZeneca
Preeclampsia
Standard 24-hour Urine Protein vs Shorter Period for Diagnosis of Pre-eclampsia
Background and project rationale: Preeclampsia is a common complication of pregnancy, affecting 6-8% of all pregnancies and constitutes a leading cause of maternal morbidity and mortality.
- Trial name
- PET and urine (NCT01881542)
- Where
- Israel
- Volunteers
- 307 people
- Sponsor
- HaEmek Medical Center, Israel
Hypertension in Pregnancy
STAMPP-HTN in a High-risk Rural Population of Women
The purpose of this study is to determine if monitored blood pressure paired with education reduces maternal mortality and morbidity during the post-partum period in a high-risk rural population of women.
- Trial name
- NCT04570124
- Testing
- Home Blood Pressure Telemonitoring
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Mississippi Medical Center
Renal Pelvis Cancer, Restless Legs Syndrome
Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in the Adverse Events…
- Conditions
- Renal Pelvis Cancer, Restless Legs Syndrome, Epilepsy, Neuropathic Pain
- Trial name
- NCT01138124
- Testing
- Gabapentin prescriptions
- Volunteers
- 54,202 people
- Sponsor
- GlaxoSmithKline
Pre-Eclampsia, Fetal Growth Retardation
Doppler and Biological Second Trimester Placental Insufficiency Screening
To assess the role of uterine artery and maternal serum leptin and lipids and their combination in screening for pre-eclampsia and small-for-gestational-age (SGA) fetuses at 20-24 weeks of gestation
- Conditions
- Pre-Eclampsia, Fetal Growth Retardation, Placental Insufficiency
- Trial name
- ARTULEP (NCT00465634)
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Tours
Preeclampsia
Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care
Pre-eclampsia (PE) is a pregnancy-associated syndrome of variable severity, classically defined by the combination of hypertension and proteinuria in a previously non-hypertensive or proteinuric patient.
- Trial name
- PRECEDE (NCT05056701)
- Testing
- annual follow-up during 10 years
- Where
- 2 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier le Mans
Preeclampsia, Periodontal Diseases
Maternal Periodontal Status and Cytokines in Preeclampsia
Background: The purpose of this study is to examine the relationship between maternal preeclampsia and periodontal parameters and the correlation of these two disorders with maternal gingival crevicular fluid levels (GCF) of…
- Trial name
- NCT03088228
- Testing
- gingival crevicular fluid collection
- Volunteers
- 80 people
- Sponsor
- Hacer Sahin Aydinyurt
Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia
Lasix for the Prevention of De Novo Postpartum Hypertension
Primary objective: To evaluate whether oral furosemide can help prevent de novo postpartum hypertension (new-onset high blood pressure after delivery) by reducing blood pressure after delivery in high-risk women.
- Conditions
- Postpartum Pregnancy-Induced Hypertension, Postpartum Preeclampsia, Hypertension, Pregnancy-Induced, Hypertension
- Trial name
- LAPP (NCT04752475)
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Columbia University
Preeclampsia, Pregnancy
Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases
At the moment, most of efforts to prevent non-transmissible chronic diseases at population level have been centered in promoting healthful behaviors like physical activity, consumption of fruits and vegetables, and discouraging…
- Conditions
- Preeclampsia, Pregnancy, Micronutrients, Exercise
- Trial name
- NCT00872365
- Testing
- Regular aerobic physical exercise, Micronutrients
- Where
- Colombia
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia
Anemia in Pregnancy, Pre-eclampsia
A Retrospective Analysis of Neevo® and NeevoDHA® Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
This study is a multi-site, retrospective chart review to determine the effect of Neevo® or NeevoDHA® (with higher folate and B12) versus standard prenatal vitamins on hemoglobin (Hgb) levels in pregnant women throughout the…
- Trial name
- NCT01193192
- Testing
- Neevo®, Prenatal vitamins
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pamlab, L.L.C.
Healthy Lifestyle, Preeclampsia
Efficiency of the Web-Based Support Program Based on the Health Promotion Model in Pregnant Women With Preeclampsia
In the literature, it has been reported that health promotion model-based care approaches are beneficial in gaining positive healthy lifestyle behaviors, taking responsibility for the individual's health and increasing the…
- Conditions
- Healthy Lifestyle, Preeclampsia, Pregnancy; Renal Disease
- Trial name
- preeclampsia (NCT05021692)
- Testing
- Web-based support program for pregnant women with preeclampsia based on the Health Promotion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Kidney Disease, Hypertension
Alpha-Adrenoceptor Vascular Function In Chronic Kidney Disease Focus On The Role Of Endothelial Nitric Oxide
The purpose of this study is to learn more about why most patients with early stages of kidney disease have high blood pressure.
- Trial name
- NCT00356265
- Testing
- Procedure: Regional phenylephrine arterial infusion
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hypertension, Pregnancy-Induced, Hypertension
Wearables to Define Postpartum Blood Pressure Trajectories and Facilitate Evidence-based Monitoring Guidelines
To better understand postpartum blood pressure changes, the investigators are proposing a study to monitor blood pressure after delivery in 100 patients who the investigators expect to have normal blood pressure (i.e.
- Conditions
- Hypertension, Pregnancy-Induced, Hypertension, Postpartum Preeclampsia, Postpartum Complication
- Trial name
- NCT06576544
- Testing
- BP Watch
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of California, San Diego
Intraocular Pressure, Delivery
The Effect of Labor on Intraocular Pressure Fluctuation in Healthy Eyes
Glaucoma is a multifactorial disease, an important risk factor of which is increased intraocular pressure. Fluctuations in intraocular pressure are often associated with vaginal birth, although intraocular pressure during active…
- Trial name
- ELIPFHE (NCT06016712)
- Testing
- SENSIMED Triggerfish Eye Lenses
- Where
- Czechia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady