Clinical trials: Hypertensive Disorders
Hypertension Complicated, Hypertrophy, Left Ventricular
Efficacy and Safety of Valsartan and Nebivolol/Valsartan in Hypertensive Patients With LVH
To assess the efficacy of Left Ventricular Hypertrophy (LVH) reduction and 24-hour blood pressure control of Valsartan 80mg or Nebivolol/Valsartan 5/80mg once daily as replacement therapy for currently treated or untreated…
- Conditions
- Hypertension Complicated, Hypertrophy, Left Ventricular, Blood Pressure
- Trial name
- BVreduce (NCT03180593)
- Testing
- Valsartan 80 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trinity Hypertension & Metabolic Research Institute
Hypertension, Potassium Imbalance
Occurrence of Dyskalemia With Treatment for Hypertension
Hypertension is a major public health issue associated with significant morbidities and mortality. Fixed-dose combination (FDC) pills, combining 2 or more classes of antihypertensive medications have considerable appeal because…
- Trial name
- OK (NCT05155436)
- Testing
- Fixed Dose Combination pill of Telmisartan 40mg and Amlodipine 5 mg
- Where
- Bangladesh
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- National Heart Foundation of Bangladesh
Hypertensive Retinopathy
Assessment of Hypertensive Retinopathy Using Neural Network "RetinAIcheck"
The current study is aimed at estimating the diagnostic effectiveness of a developed neural network "RetinAIcheck" in grading the severity of hypertensive retinopathy in patients of the Russian population.
- Trial name
- NCT07471971
- Testing
- Convolutional neural network "RetinAIcheck"
- Where
- Russia
- Volunteers
- 755 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Aging Well, Training Group, Sensitivity
Effect of Distance Physical Exercise on Mobility and Sleep Quality of Hypertensive Elderly Women
The objective of the present study was to verify the impact of physical exercise at a distance (EFAD) on the level of mobility and quality of sleep of hypertensive elderly women.
- Trial name
- NCT05991505
- Testing
- Physical exercise
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hypertension
Early-Warning Intervention for Heat and Cold in Older Hypertensive Patients: Impact on Sleep Quality
This cluster-randomized trial, conducted in Tianjin, China, aims to evaluate the effectiveness of integrating a digital health risk early warning tool for heat with self-monitoring.
- Trial name
- NCT06045403
- Testing
- Issuing health risk warning for a heat or cold, A digital heat or cold health risk early warning tool, Perform daily self-monitoring of their BP and ECG
- Where
- China
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Tiantian Li
Retinal Disease, Retinal Detachment
High Resolution Optical Coherence Tomography
Comparison of high-resolution optical coherence tomography (High-Res-OCT) to conventional imaging modalities for the diagnosis of eye diseases
- Conditions
- Retinal Disease, Retinal Detachment, Retinal Vein Occlusion, Retinal Dystrophy
- Trial name
- NCT05130385
- Testing
- High-resolution optical coherence tomography (High-Res-OCT), Standard spectral domain OCT (SD-OCT)
- Where
- Switzerland
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Elderly, Hypertension
Unsupervised Physical Activity in Elderly
To evaluate safety and the effects of a unsupervised physical activity program (USPAP) over blood pressure (BP), physical fitness (PF) and quality of life (QL) of elderly hypertensive patients.
- Conditions
- Elderly, Hypertension, Physical Conditioning
- Trial name
- NCT02976506
- Testing
- Unsupervised exercise program, Physical fitness and quality of life
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Hypertension
Effect of Motivational Interview as a Strategy in the Reduction of Blood Pressure.
This randomized clinical trial was designed to test the effectiveness of Motivational Interviewing in lowering blood pressure during six months follow-up.
- Trial name
- NCT02892929
- Testing
- Motivational interviewing, Prescriptive Consultation
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pre-Eclampsia
Prospective Case-Control Study of Cardiovascular Changes in Pregnancy Related Hypertensive Disorders
This is a research study to understand the changes in the heart and the cardiovascular system that may occur in women who develop high blood pressure during pregnancy.
- Trial name
- ARTSEN (NCT04713228)
- Testing
- ARTSENS Pen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Preeclampsia, Hypertensive Disorder of Pregnancy
Progesterone Preeclampsia
This randomized controlled trial evaluates whether nightly vaginal micronized progesterone (400 mg) initiated before 12 weeks' gestation reduces the incidence of preeclampsia in low-risk pregnant individuals.
- Trial name
- NCT07448597
- Testing
- Progesterone supplementation
- Where
- United States
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pre-Eclampsia, Eclampsia
Catestatin and Hypertension in Pregnancy
Catestatin is a kind of protein involved with cardiovascular disease. Accumulated evidence shows that Catestatin may be a predictor of primary hypertension, but whether it plays the same role in pregnant hypertensive disorders…
- Conditions
- Pre-Eclampsia, Eclampsia, Hypertension, Pregnancy-Induced, Hypertension in Pregnancy
- Trial name
- NCT03200743
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yuchen Pan
Hypertension
NSAID Use in Postpartum Hypertensive Women
Women who have the diagnosis of hypertension (pre-pregnancy and pregnancy induced) and deliver an infant via vaginal delivery will be placed into two groups in the postpartum period.
- Trial name
- NCT02902172
- Testing
- Acetaminophen, NSAID
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Preeclampsia (PE), Hypertensive Disorder of Pregnancy
Endothelial Dysfunction for Prognosis In Patients With preeClampSia
Preeclampsia is a pregnancy-specific hypertensive disorder and can progress rapidly to severe adverse outcomes affecting both the mother and the fetus.
- Trial name
- EPICS (NCT06912477)
- Testing
- Hyperspectral imaging, Further markers of endothelial dysfunction
- Where
- Germany
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Cardiovascular Diseases, Hypertension
Vascular Dysfunction in Hypertensive Postmenopausal Women
The purpose of this study is to investigate the role of ET-1 in mediating vasoconstrictor tone in hypertensive postmenopausal women (PMW) alone and in combination with a commonly prescribed Angiotensin II (ANG II) antagonist.
- Trial name
- NCT03371823
- Testing
- Normotensive, Hypertensives
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Hypertension, Patient Engagement
Roy Adaptation Model in Hypertensive Patients
The aim of this study was to determine the effect of training given according to the Roy Adaptation Model on medical treatment and physiological, psychological and social adaptation to the disease in individuals with hypertension.
- Conditions
- Hypertension, Patient Engagement, Nurse-Patient Relations
- Trial name
- NCT05221424
- Testing
- Patient Education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Hypercholesterolemia, Hypertension
Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients
In this study, Amlodipine has been used to study its effects in newly diagnosed hypertensive patients.
- Conditions
- Hypercholesterolemia, Hypertension, Cholesterol Deposition
- Trial name
- NCT05467384
- Testing
- Amlodipine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ayub Teaching Hospital
Obese, Hypertension
Effect of Green Tea in Obese Pre-hypertensive Women
The purpose of this study is to evaluate the effects of green tea on body weight, waist circumference, metabolic profile, inflammation, blood pressure and endothelial function in obese pre-hypertensive women.
- Trial name
- NCT01861171
- Testing
- Green Tea
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Hypertensive Disease, Pain, Postoperative
Effect of Acute Arterial Hypertension on Morphine's Requirements and Postsurgical Pain.
The purpose of this randomized clinical trial is to evaluate the effect of acute arterial hypertension maintained during surgery on morphine's requirements in patients undergoing laparoscopic cholecystectomy
- Trial name
- NCT01897155
- Testing
- SBP 20-30% over baseline, SBP 20-30% under baseline
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Blood Pressure, Hypertension
Community-based Implementation of Adapted STAC
This study is being done to adapt the Staying Healthy After Childbirth (STAC) intervention for implementation among Black Women and Birthing Persons (WBP).
- Conditions
- Blood Pressure, Hypertension, Pregnancy Related, Health Equity
- Trial name
- NCT06689930
- Testing
- PDSA Cycles
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Hypertension, Kidney Transplant
Melatonin and Adiponectin in Hypertensive Kidney Transplant
Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients.
- Trial name
- NCT00498576
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center