Clinical trials: Hypertensive Disorders
Dyslipidemia, Oxidative Stress
Brazil Nut Consumption in Microvascular Endothelial Function, Oxidative Stress and Metabolic Abnormalities
The purpose this research is to check the effect of Brazil Nuts consumption in oxidative stress, metabolic abnormalities and microvascular endothelial function dyslipidemic and hypertensive patients.
- Trial name
- NCT01990391
- Testing
- Brazil nut flour
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Hypertension
Changes in Central Arterial Pressure When Comparing ACOG Hypertensive Urgency Protocols
The investigators plan to monitor the central blood pressure in women with severely elevated blood pressures (160/110) in pregnancy in the acute setting.
- Trial name
- NCT02933593
- Testing
- Labetalol, Hydralazine, nifedipine
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Louis University
Preeclampsia, Maternal
A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women
Primary Endpoint: Quantify the hemodynamic changes in preeclampsia using the non-invasive Nexfin device. Secondary Endpoint: Determine if measurable hemodynamic changes are statistically correlated with B-type natriuretic peptide…
- Conditions
- Preeclampsia, Maternal, Hypertension, Pregnancy
- Trial name
- NCT02527018
- Testing
- Sphygmomanometer
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Hypertension
Reduction Of Dietary Salt Intake To Control Systolic Blood Pressure In Hypertensive Older Patients
REPRESS is an open label, pragmatic, multicenter, randomized controlled phase III trial with blinded endpoint with 1:1 (intervention to control arm) allocation ratio.
- Trial name
- REPRESS (NCT05976477)
- Testing
- educational intervention
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pre-Eclampsia, Pregnancy Induced Hypertension
Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies
Study background High blood pressure during pregnancy is a worldwide health problem that can be dangerous to mothers and commonly causes premature birth and small babies.
- Conditions
- Pre-Eclampsia, Pregnancy Induced Hypertension, Pregnancy Related
- Trial name
- CAREFOL-HT (NCT05434195)
- Testing
- Arcofolin® 5-Methyltetrahydrofolate
- Where
- 2 sites in United Kingdom
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Obesity, Pre-hypertension
Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure
Obesity is a major risk factor for premature arterial abnormalities including high blood pressure and increased stiffness. Previous studies have shown that weight loss via lifestyle modifications is associated with a decrease in…
- Conditions
- Obesity, Pre-hypertension, Hypertension
- Trial name
- NCT01371370
- Testing
- Resistance exercise training, Hypocaloric diet, Resistance exercise training & diet
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Florida State University
Gout
Effect of Aquatic Exercise and Traditional Physical Therapy on Gout in Hypertensive Menopausal Women With Hyperuricemia
Aquatic Exercise and traditional physical therapy are effective methods of treatment for gout and hypertension in menopausal women.
- Trial name
- NCT05454423
- Testing
- the Aquatic exercises +Traditional physical therapy programs +anti-hyperuricemia medication, traditional physical therapy + anti-hyperuricemia medication
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Merit University
Hypertension
Cognitive Dysfunction in Hypertensive Patients Having Spine Surgery
While hypotension during general anesthesia has routinely been considered to be a tolerable abnormality with little clinical consequence, the proposed study takes the innovative approach of defining hypotensive events within the…
- Trial name
- HTN (NCT01140854)
- Testing
- Lumbar spine surgery, Neurologic/neuropsychometric examinations
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hypertension, Metabolic Syndrome
Diva - The Effects Of 12 Weeks Of Treatment With High Dose Valsartan (320 Mg) To Amlodipine On Endothelial Function In Hypertensive Subjects With The Metabolic Syndrome
A STUDY ON WHETHER AN ANTIHYPERTENSIVE MEDICATION PREVENTS DAMAGE TO WALLS OF VEINS IN FEMALE PATIENTS WITH THE METABOLIC SYNDROME (OVERWEIGHT AND OTHER DISORDERS).
- Trial name
- NCT00241150
- Testing
- VALSARTAN
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Novartis
Hypertension
Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients
Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfort such as adequate…
- Trial name
- NCT06927726
- Testing
- 4% Articaine HCL With 1:100,000 Epinephrine, 3% plain mepivacaine HCL
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Hypertension, Menopause
The Effects of Stair Climbing on Arterial Stiffness, Blood Pressure and Leg Strength in Stage-1 Postmenopausal Women
We used a parallel experimental design. Following an initial screening and familiarization session of study tests and procedures, eligible postmenopausal women were randomly assigned to a stair climbing (SC) group or…
- Trial name
- NCT03254251
- Testing
- Stair climbing
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Pusan National University
Hypertensive Disease
Activating Media for Salt Reduction
Mass media plays more and more important role in health education, especially in some chronic diseases which related closely with the behavior and habits.
- Trial name
- NCT03074851
- Testing
- low sodium salt, informational intervention
- Where
- China
- Volunteers
- 516 people, healthy volunteers welcome
- Sponsor
- The George Institute for Global Health, China
Hypertensive Disorder of Pregnancy, Vitamin D Deficiency
Vitamin D Deficiency With Selected Vitamin D Receptor Gene Polymorphism in Gestational Hypertension
This study aim to look into the prevalence of Vitamin D deficiency among Malaysian pregnant women and its associated risk factors.
- Trial name
- NCT05659173
- Testing
- Blood taking
- Where
- Malaysia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Hypertensive Retinopathy
Non-invasive Measurement of Retinal Blood Flow Based on Vessel Analysis and Fourier Domain Optical Coherence Tomography in Patients With Hypertensive Retinopathy
Recently, a new and sophisticated method for assessment of retinal blood flow and retinal blood flow velocity profiles has become available.
- Trial name
- NCT01753648
- Testing
- Dynamic Vessel Analyzer, FDOCT, Ocular perfusion pressure
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hypertension
Acute Effect of Agiotensin-(1-7) in Healthy and Hypertensive Subjects
In the modern concept of Renin-angiotensin System, Angiotensin-(1-7) plays a key role and demonstrates promising therapeutic potential due to it is generally opposite effects to Angiotensin II.
- Trial name
- Ang-(1-7) (NCT03001271)
- Testing
- Angiotensin 1-7
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Hypertension
Acute Effects of Different Exercises on Blood Pressure in Hypertensive Subjects
Lifestyle changes might reduce cardiovascular risk due to the decrease in blood pressure (BP). However, whether combining aerobic and resistance exercises affect BP and hemodynamic parameters, as well as arterial stiffness and…
- Trial name
- NCT02987452
- Testing
- aerobic exercise, resistance exercise, combined exercise
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heitor Moreno Junior
Hypertension, Diabetes
Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance Arteries
This study will be performed only at the Jewish General Hospital. It will investigate the effect of treatment with aliskiren, an inhibitor of renin, a substance produced by the kidney that constricts arteries and raises blood…
- Trial name
- NCT01480791
- Testing
- Aliskiren vs. hydrochlorothiazide, Hydrochlorothiazide
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Hypertrophic Cardiomyopathy, Hypertensive Heart Disease
Differentiation HHD From HCM (EARLY-MYO-HHD)
Differentiating hypertrophic cardiomyopathy (HCM) from hypertensive heart disease (HHD) unavoidably encounters diagnostic challenges especially in patient of suspected HCM with history of hypertension.
- Trial name
- NCT03271385
- Testing
- evaluated by the predetermined differentiating formula
- Where
- China
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Diabetes Mellitus, Type 2
Pharmacist-led Intervention in Treatment Non-adherence in Southwestern Nigeria
Summary of the Research Medication non-adherence has a huge economic impact on the patient and the society at large. World Health Organization (WHO) has suggested that noncompliance with medication is a common problem which often…
- Trial name
- NCT04712916
- Testing
- Health education
- Where
- Nigeria
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Hypertension, Insulin Resistance
Treatment of Insulin Resistance in Hypertensive, Obese Adolescents
In this study, we propose using telmisartan, an angiotensin II receptor antagonist with PPAR-gamma modulating activity, for a 12-week period to decrease blood pressure and insulin levels in obese, hypertensive children.
- Conditions
- Hypertension, Insulin Resistance, Dyslipidemia
- Trial name
- NCT00185705
- Testing
- Telmisartan
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University