Clinical trials: Hypertensive Disorders
Pre-hypertension
A Study to Investigate the Effect of a Nitric Oxide Supplementation on Pre- and Mildly Hypertensive Adults
This study will investigate the effect of a nitric oxide supplementation product, Neo40 Daily®, on blood pressure in pre-hypertensive and mildly hypertensive adults.
- Trial name
- 15NBHN (NCT02679248)
- Testing
- Neo40 Daily®
- Where
- 2 sites in Canada
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Pre-hypertension, Hypertension
The Effects of Polyphenol-rich Berry Juice on Blood Pressure in Hypertensive Subjects
The purpose of this study is to investigate the effects of berry juices containing different levels of polyphenols on blood pressure and other cardiovascular risk factors.
- Trial name
- NCT01568983
- Testing
- Mana-juice, Optijuice
- Where
- Norway
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Pregnancy, Blood Pressure Measurement in Pregnancy
Arm Position and Blood Pressure Measurement Accuracy During Pregnancy
Accurate blood pressure measurement is essential during pregnancy, as blood pressure readings guide clinical decisions related to the diagnosis and management of hypertensive disorders of pregnancy.
- Conditions
- Pregnancy, Blood Pressure Measurement in Pregnancy, Hypertensive Disorder of Pregnancy
- Trial name
- NCT07405723
- Testing
- Arm Supported at Heart Level, Arm Supported on Lap, Arm Unsupported at Side
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Abruptio Placentae; Affecting Fetus or Newborn
Normotensive and Hypertensive Placental Abruptions
Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process.
- Trial name
- NCT04449601
- Testing
- clinical assesment
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Hatice Akkaya
Hypertension,Essential, Exercise Activity
Effect of High-Intensity Interval Training Compared to Hydrochlorothiazide on Ambulatory Blood Pressure
The number of persons with hypertension is increasing and with it the number of related cardiovascular events and related functional or cognitive declines.
- Trial name
- DIISCCO (NCT04103411)
- Testing
- 24h-Ambulatory Blood Pressure
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Anil Nigam
Microvascular Angina, Hypertension
Effects of Intensive Long-Term Vasodilation in Hypertensive Patients With Microvascular Angina Pectoris
The purpose of this study is to determine if long-term vasodilatory treatment is more effective than the standard treatment in hypertensive patients with microvascular angina pectoris
- Trial name
- NCT00424801
- Testing
- Lercanidipine, Valsartan, Nicorandil
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Depression, Hypertension
Treatment Effects on Platelet Calcium in Hypertensive and Depressed Patients
This study aims to determine if treatment with an SSRI antidepressant medication, paroxetine, is associated with cellular calcium response to serotonin, platelet serotonin receptors, and improvement in mood in depressed patients…
- Trial name
- NCT00018759
- Testing
- paroxetine, ongoing psychological screening
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hypertension, Pregnancy-Induced
Hemodynamic Assessment of Healthy and Hypertensive Pregnant Women by Non-Invasive Bio-Reactance
The purpose of this study is to determine whether a noninvasive method of measuring certain aspects of blood circulation (e.g., blood pressure, cardiac output) is an accurate and reliable method to detect changes in pregnant…
- Trial name
- NCT00949260
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hypertension
The Effect of Hibiscus Sabdariffa L. Tea on Blood Pressure
The goal of this study is to find out whether the plant compounds present in Hibiscus sabdariffa, a plant commonly used in herbal tea blends and other beverages, will have a beneficial effect on blood pressure in people with…
- Trial name
- NCT00175110
- Testing
- herbal therapy/botanical therapy (Hibiscus sabdariffa)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Tufts University
Thoracic Aortic Aneurysm (TAA), Aortic Dissection
POCUS Screening for TAA in Hypertensive Patients in the ED
The investigators are going to recruit hypertensive patients in the emergency department of Prince of Wales Hospital. Point-of-care ultrasound of the aorta and measurements of the aortic diameter will be obtained.
- Trial name
- NCT06854588
- Testing
- Point-of-care ultrasound
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,483 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Uveitic Glaucoma, Anterior Uveitis
Aqueous Humor Dynamics and Hypertensive Uveitis
Uveitis is a disease that affects over 2 million people around the globe, and can ultimately lead to blindness. The proportion of patients with uveitis who become blind has not been reduced over the past 30 years, and this is…
- Trial name
- NCT02765308
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Preeclampsia (PE), Hypertension ,Pregnancy
Retinal and Choroidal Microcirculation in Preeclampsia: An OCTA Study
Preeclampsia is a multisystemic and multifactorial disorder that complicates pregnancy and is characterized by new-onset hypertension after the 20th week of gestation accompanied by proteinuria or systemic findings such as renal…
- Conditions
- Preeclampsia (PE), Hypertension ,Pregnancy, Retinal Microvascular Changes, Hypertensive Disorders of Pregnancy
- Trial name
- PE-OCTA (NCT07874191)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Heart Failure With Preserved Ejection Fraction, Hypertrophic Cardiomyopathy
Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Heart scarring, also known as fibrosis, plays a major role in a lot of heart muscle abnormalities. These abnormalities of the heart muscle can lead to major issues such as symptoms of heart failure, dangerous heart rhythm…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Hypertrophic Cardiomyopathy, Cardiac Sarcoidosis, Hypertensive Heart Disease
- Trial name
- CHIEFTain (NCT06409585)
- Testing
- 68Ga-FAPI or 18F-AlF-FAPI cardiac PET-MR, Echocardiogram, Cardiac MRI
- Where
- United Kingdom
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Asymptomatic Atrial Fibrillation
Subclinical Atrial Fibrillation Home Monitoring in Hypertensive Patients
Atrial fibrillation is a highly prevalent and incidental arrhythmia, often asymptomatic, and frequently detected incidentally or in association with a stroke.
- Trial name
- NCT07058831
- Testing
- Home ECG monitoring
- Where
- Argentina
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Research Center Rosario British Sanatorium
Hypertension, Kidney Transplant
Melatonin and Adiponectin in Hypertensive Kidney Transplant
Recently we have shown that melatonin secretion is impaired in rats with metabolic syndrome. We have also demonstrated that exogenic melatonin supplementation can improve blood pressure profile in nondipper patients.
- Trial name
- NCT00498576
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Preeclampsia (PE), Hypertensive Disorder of Pregnancy
Endothelial Dysfunction for Prognosis In Patients With preeClampSia
Preeclampsia is a pregnancy-specific hypertensive disorder and can progress rapidly to severe adverse outcomes affecting both the mother and the fetus.
- Trial name
- EPICS (NCT06912477)
- Testing
- Hyperspectral imaging, Further markers of endothelial dysfunction
- Where
- Germany
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Hypertension, Menopause
8 Weeks of L-CIT Supplementation and LIRET on Vascular Function in Hypertensive Postmenopausal Women
The overall objective of this project is to bring forth evidence that L-Citrulline (L-CIT) supplementation and low intensity resistance exercise training (LIRET) alone and combined will improve vascular function and muscle…
- Trial name
- NCT05227781
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Hypertension
Acute Effects of Beet Juice Intake on the Vascular Function of Hypertensive Patients
To assess the acute effects of only one dose of beet juice on hypertensive subjects treated with vascular endothelial function parameters, using the microvascular reactivity method.
- Trial name
- NCT04020796
- Testing
- Beetroot juice
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Pedro Ernesto
Hypertension, Cardiovascular Disease
Nurse-led Reminder Program for the Prevention of Cardiovascular Diseases
A number of strategies have been evaluated to improve the prevention and control of the main cardiovascular (CVD) risk factors. Nursing telephonic and tele-counseling individualized lifestyle educational programs were found to…
- Trial name
- NCT01823588
- Testing
- Nurse-led reminder through email.
- Where
- 2 sites in Italy
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Hypertension, Pregnancy Induced, Preeclampsia
Blood Pressure Variability Effect on Right Ventricular Strain in Women With Hypertensive Disorders With Pregnancy
The goal of this observational study is to learn about the potential effect of blood pressure variability changes on right ventricular strain in pregnant women with gestational hypertension or pre-eclampsia
- Trial name
- NCT06100484
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aswan University