Clinical trials: Hyperthyroidism
Thyroid Eye Disease (TED), Graves' Disease
Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye Disease
The primary objective of study is to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ETHY-001 in healthy volunteers and participants with Thyroid Eye Disease after single subcutaneous doses.
- Conditions
- Thyroid Eye Disease (TED), Graves' Disease, Eye Diseases, Hereditary, Eye Diseases
- Trial name
- NCT07885605
- Testing
- ETHY-001
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ethyreal Bio, Inc.
Graves' Orbitopathy, Graves' Disease
Microbiota and Immune SignatureS of Graves' Disease and Orbitopathy
Graves' disease (GD) is the commonest cause of hyperthyroidism, characterised by anti-thyrotropin receptor autoantibodies (TRAb) persistently stimulating the thyroid gland.
- Conditions
- Graves' Orbitopathy, Graves' Disease, Graves' Ophthalmopathy, Basedow Disease
- Trial name
- MISS:GO (NCT07870161)
- Testing
- Aspiration 0
- Where
- Italy
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Hypothyroidism, Hypertension
The Effect of SPU on Hormonal and Cardiometabolic Factors
The study examines the immediate effect of soleus pushup exercise on cardiometabolic and hormonal functions among hypothyroid patients.
- Conditions
- Hypothyroidism, Hypertension, Healthy Adult, Diabete Mellitus
- Trial name
- NCT07688824
- Testing
- Soleus pushup exercise
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Graves Orbitopathy, Hyperthyroidism
Development of a Non-Invasive Prognostic Test for Graves Orbitopathy
The aim of this research project is to develop a non-invasive, simple, robust, and sensitive prognostic test that can identify hyperthyroidism patients who are at risk of developing Graves' Orbitopathy.
- Trial name
- GoPro (NCT07472062)
- Testing
- Schirmer's test
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Hyperthyroidism, Autoimmune, Cardiovascular Abnormalities
Clinical Application of Al18F-NOTA-FAPI-04 PET/CT or PET/MRI Imaging in Malignant Tumor,Cardiovascular or Immune Disease
This prospective, single-center study investigates the biodistribution, dosimetry, safety, diagnostic performance of Al18F-NOTA-FAPI PET imaging in patients with malignant tumor,cardiovascular or immune disease.
- Conditions
- Hyperthyroidism, Autoimmune, Cardiovascular Abnormalities, Malignant Tumor
- Trial name
- NCT07400224
- Testing
- Al18F-NOTA-FAPI PET/CT(or PET/MRI)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Hyperthyroidism
Evaluation of Renal Function in Patients With Hyperthyroidism
To evaluate the effect of subclinical and overt Hyperthyroidism in renal function
- Trial name
- NCT06591858
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hyperthyroidism/Thyrotoxicosis
LIthium as Bridging thErapy Prior to Radioactiveiodine in hyperThYroidism
A prospective randomised controlled open label, single centre study. subjects will be randomised into lithium or carbimazole arms in a 1:1 ratio.
- Trial name
- LIBERTY (NCT05512715)
- Testing
- radioactive iodine
- Where
- Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Central Hypothyroidism, Hypothyroidism
Metabolomics of Thyroid Hormones
The aim of this study is to develop a metabolome signature of thyroid hormone status. The metabolome signature could be useful in diagnosis and treatment of thyroid dysfunction diseases, especially in cases where TSH cannot be…
- Conditions
- Central Hypothyroidism, Hypothyroidism, Hyperthyroidism
- Trial name
- MATcH (NCT03823859)
- Testing
- Indirect calorimetry, Dual energy X-ray Absorptiometry (DXA), Blood sampling
- Where
- Switzerland
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Hyperthyroidism
Exercise Capacity, Physical Activity Levels in Patients With Hyperthyroid
The primary aim of the study is to evaluate physical activity level and functional exercise capacity in patients with hyperthyroid.
- Trial name
- NCT04825964
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Melasma, Hyperthyroidism
Comparative Study of mMASI Before and After Hyperthyroid Therapy in Hyperthyroid Subjects With Melasma
Study's objectives are to determine proportion of melasma cases in hyperthyroid patients and to compare severity of melasma before and after medications of three months hyperthyroid therapy using modified melasma area and…
- Trial name
- NCT04346901
- Testing
- Thiamazol
- Where
- Indonesia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Pregnancy Related, Hypothyroidism
TSHβX1 and D2 THR92ALA in Pregnancy
Thyroid diseases are pathologies that frequently affect pregnant women causing serious complications. This current research aims to find out whether the expression of TSHβX1 splice variant and D2 Thr92Ala polymorphism in the DIO2…
- Conditions
- Pregnancy Related, Hypothyroidism, Hyperthyroidism
- Trial name
- NCT03612908
- Where
- Mexico
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
Hyperthyroid
Assessment of Intellectual, Psychological and Behavioural Developments Between 6 and 9 Years of the Children Born to Hyperthyroid Mothers During Their Pregnancy
1. MAIN OBJECTIVE : To assess the consequences of a maternal hyperthyroïd during pregnancy on intellectual development of the child from 6 to 9 years 2. SECONDARY OBJECTIVES : 1.
- Trial name
- EDIEMHYPER (NCT01779817)
- Testing
- Assessment of intellectual development, capacities of attention, learning process and degree of hyperactivity of the children between 6 and 9 years.
- Where
- 13 sites in France
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Hypothyroidism, Subclinical Hypothyroidism
Thyroid Disorders in Malaysia: A Nationwide Multicentre Study
This will be a population based study looking at the prevalence of thyroid disorders in Malaysia (including hypo- and hyperthyroidism, subclinical hypo- or hyperthyroidism) and its association with different ethnicity and iodine…
- Conditions
- Hypothyroidism, Subclinical Hypothyroidism, Hyperthyroidism, Subclinical Hyperthyroidism
- Trial name
- MyEndo-Thyroid (NCT02190214)
- Volunteers
- 2,498 people, healthy volunteers welcome
- Sponsor
- International Islamic University Malaysia
Hyperthyroidism
Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism
Clustering of various metabolic parameters including abdominal obesity, hyperglycaemia, low high-density lipoprotein cholesterol, elevated triglycerides and hypertension have been used worldwide as metabolic syndrome to predict…
- Trial name
- NCT02812888
- Testing
- thionamide treatment for 3 months
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hu Hao
Hyperthyroidism, Tomography
Comparison of SUV Using SPECT/CT Between Grave's Disease Patients and Normal Humans
The purpose of this study is to find out the capacity of standardized uptake value (SUV) using single-photo emission computed tomography and computed tomography (SPECT/CT) in diagnosing Grave's Disease (hyperthyroidism).
- Conditions
- Hyperthyroidism, Tomography, Emission-Computed, Single-Photon
- Trial name
- NCT02772705
- Where
- 9 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West China Hospital