Clinical trials: Hypertonia
Muscle Spasticity, Hypertonia, Muscle
Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals
To assess the safety and tolerability of single and multiple doses of MTR-601 in normal healthy volunteers under fed and fasted conditions. To evaluate the plasma and urine pharmacokinetics (PK) of MTR-601.
- Conditions
- Muscle Spasticity, Hypertonia, Muscle, Cerebral Palsy, Multiple Sclerosis
- Trial name
- NCT06117020
- Testing
- MTR-601
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Motric Bio
Fat Reduction, Muscle Tone Increased
Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.
Multi-center, three-arm, randomized, evaluator-blinded study of electrical muscle stimulation (EMS) and/or 1064 nm diode laser, pulsed electromagnetic field (PEMF) and vacuum assisted radio frequency (RF) using the Venus Bliss…
- Trial name
- NCT05256771
- Testing
- EMS, 1064 nm diode laser, RF/PEMF
- Where
- 3 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Stroke, Spasticity
Efficacy of Shock Wave Therapy in Post-Stroke Muscle Spasticity Management
The goal of this clinical trial is to evaluate the efficacy and safety of shock wave therapy (SWT) in reducing muscle spasticity in patients who have suffered a stroke.
- Conditions
- Stroke, Spasticity, Post-stroke, Muscle Hypertonia
- Trial name
- SWT-PI (NCT06815328)
- Testing
- Shock Wave Therapy (SWT), Active Comparator - Conventional Therapy
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Stroke, Muscle Hypertonia
Antagonist Activation Measurement at the Ankle Using High-density and Bipolar Surface EMG in Chronic Hemiparesis
In chronic hemiparesis, abnormal antagonist muscle activation in the paretic lower limb contributes to impair ambulation capacities.
- Conditions
- Stroke, Muscle Hypertonia, Spasticity, Muscle
- Trial name
- CC2017 (NCT06099132)
- Testing
- Electromyographic measurements
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Henri Mondor University Hospital
Muscle Hypertonia, Rib Syndrome
Reactibility of Muscle Volume to Ribs Mobilization According to Mojžíšová
The goal of this study is to evaluate a top-rated Prague rehabilitation school´s method. Part of Prague rehabilitation school is called Mojžíšová Method, which is mainly used for the treatment of back pain and woman´s…
- Trial name
- NCT04685785
- Where
- Czechia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Muscle Hypertonia, Postural Scoliosis
Load During Sweep Rowing and the Influence on the Posture
The aim is to assess the influence of asymmetric training on the locomotor system in sweep rowers. To analyse possible changes objectively, the axial position of the hull will be assessed using Moiré topography, and the symmetry…
- Conditions
- Muscle Hypertonia, Postural Scoliosis, Postural; Defect
- Trial name
- NCT05685563
- Testing
- DIERS formetic 4D
- Where
- Czechia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Pain, Temporomandibular Joint Disorders
Effectiveness of Physiotherapy Treatments in Temporomandibular Joint Dysfunction
The study will determinate the influence of four selected physiotherapeutic procedures on the pain intensity, the bioelectrical activity of the masseter muscle, and the range of mandibular mobility in patients with TMDs…
- Conditions
- Pain, Temporomandibular Joint Disorders, Muscle Hypertonia, Myofacial Pain
- Trial name
- NCT05619380
- Testing
- physiotherapy treatment
- Where
- Poland
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Mobility Limitation, Stiffness of Right Ankle, Not Elsewhere Classified
The Relation of Ankle Mobility and Achilles Tendon, Plantar Fascia and Iliotibial Band Mechanical Properties
The myotonometric assessment is becoming popular and important in athletic population. It is mentioned an alternate method than expensive methods, and it is easy and reliable assessment.
- Conditions
- Mobility Limitation, Stiffness of Right Ankle, Not Elsewhere Classified, Stiffness of Left Ankle, Not Elsewhere Classified, Tone Increased, Muscle
- Trial name
- NCT04737226
- Testing
- myotonometric assessment, Ankle mobility assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Pain, Stomatognathic Diseases
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
- Conditions
- Pain, Stomatognathic Diseases, Muscle Hypertonia, Myofacial Pain Syndromes
- Trial name
- NCT05021874
- Testing
- Four different physiotherapy treatment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Muscle Tone Increased, Ultrasonography
Quantitative Evaluation of Muscle Tone Using Elastic Ultrasound
The test subjects were selected from patients with clinical manifestations in muscle tone and healthy volunteers. Elbow flexor is the main target muscle.
- Trial name
- NCT04275401
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Muscle Tone Increased
HIFEM for Arms, Lower Limbs, and Oblique Muscles
Evaluation of HIFEM treatments for strengthening and toning of arms, lower limbs and oblique muscles.
- Trial name
- NCT04426526
- Testing
- BTL 799-2
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Muscle Tone Increased
High-Intensity Focused Electromagnetic (HIFEM) Field Device in Women After Childbirth
Evaluation of use of the High-Intensity Focused Electromagnetic (HIFEM) Field Device in women after childbirth.
- Trial name
- NCT03758690
- Testing
- High-Intensity Focused Electromagnetic (HIFEM) Field Device
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Muscle Tone Increased
MRI Evaluation of Change in Gluteal Muscles Following the Treatment With HIFEM Device
This study will use magnetic resonance imaging (MRI) to evaluate changes in gluteal muscle following the treatment with HIFEM stimulation for aesthetic improvement of buttocks.
- Trial name
- NCT03815747
- Testing
- High-Intensity Focused Electromagnetic (HIFEM) Field Device
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Vaginismus, Sexual Dysfunctions
Evaluation and Comparison of Women Pelvic Floor With and Without Sexual Dysfunction (Vaginismus)
Sexuality is considered one of the pillars of quality of life, an integral part of the personality of each individual. Being a basic human being need, it cannot be separated from other aspects of life.
- Conditions
- Vaginismus, Sexual Dysfunctions, Muscular Hypertonicity, Muscle Tone Poor
- Trial name
- NCT03176069
- Testing
- Evaluation and Comparison of women pelvic floor with and without sexual dysfunction, The physiotherapeutic treatment
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Muscle Hypertonia, Reflex, Abnormal
Optimal Interstimulus Interval For Consecutive H-Reflex Responses In Patients With Spasticity
This study evaluates the optimal interstimulus interval for consecutive H-reflex responses in patients with spasticity.
- Trial name
- NCT04005937
- Testing
- H-reflex
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Hamstring Injury, Muscle Tone Increased
Cranial Laser Reflex Technique for Hamstring Function
Purpose: To conduct a pilot study of the effect of Cranial Laser Reflex Technique (CLRT) compared with sham laser on hamstring muscle flexibility, strength, and pain pressure threshold.
- Conditions
- Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
- Trial name
- CLRTHam (NCT03044106)
- Testing
- CLRT
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Spasticity, Muscle, Muscular Diseases
Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity
The purpose of this study is to improve spasticity diagnosis through development of a simple physical examination guide for primary care providers to identify patients who would benefit from being referred to a movement disorders…
- Conditions
- Spasticity, Muscle, Muscular Diseases, Musculoskeletal Disease, Muscle Hypertonia
- Trial name
- NCT03209960
- Testing
- Bedside Referral Tool, Neurological Examination
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Spasticity, Muscle, Muscular Diseases
Using Telemedicine to Improve Spasticity Diagnosis Rates
The purpose of this study is to test the reliability of using telemedicine so a neurologist can remotely identify residents of a long-term care facility who should be referred to a neurologist for an in-person spasticity…
- Conditions
- Spasticity, Muscle, Muscular Diseases, Musculoskeletal Disease, Muscle Hypertonia
- Trial name
- NCT03211390
- Testing
- Neurological Examination, Teleneurological Examination
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Spasticity, Muscle, Muscular Diseases
Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility
The purpose of this study is to improve spasticity diagnosis through exploration of potential new diagnostic markers for spasticity that can assist in diagnosis and referral.
- Conditions
- Spasticity, Muscle, Muscular Diseases, Musculoskeletal Disease, Muscle Hypertonia
- Trial name
- NCT03250988
- Testing
- Neurological Examination
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Cerebral Palsy, Muscle Hypertonia
Hypertonia in Patients With Cerebral Palsy
This study will classify types of hypertonia in patients with cerebral palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension.
- Trial name
- NCT00123708
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)