Clinical trials: Hypertonic Disorder
Nephropathy
Effect of Hypertonic Sodium Chloride on Urinary Biomarkers in Healthy Subjects and Patients With Chronic Kidney Disease
Patients with chronic kidney disease (CKD) have a defect in the tubular reabsorption of sodium, and therefore the ability to excrete a sodium load is diminished compared to healthy subjects.
- Trial name
- CASE (NCT01623661)
- Testing
- hypertonic saline
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Temporomandibular Joint Disorders
Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection
Dysfunction of the jaw, associated with pain in the jaw or about the jaw in the face can be quite long lasting and debilitating.
- Trial name
- NCT01617356
- Testing
- Injection of 20% dextrose/ 0.2% lidocaine, Injection of 1 ml of 0.8 SW/0.2% lidocaine
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Frusso, Ricardo, M.D.
Nephropathy
The Effects of Isotonic and Hypertonic Saline Infusion on Renal Biomarkers in Healthy Young Subjects
The kidneys have numerous salt and water channels and play a major role in the regulation of sodium and water. We do not know how these channels work in certain water and sodium accumulating medical conditions.
- Trial name
- NARA (NCT01414088)
- Testing
- isotonic saline 0,9 mg/ml, hypertonic saline 2,9 mg/ml, glucose 5%
- Where
- Denmark
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Dehydration
Biomarkers for Noninvasive Assessment of Human Hydration
Low levels of dehydration (the loss of body water corresponding to 2% of the body weight), deteriorate physical and cognitive performance and may also be linked to a number of chronic diseases.
- Trial name
- NCT01507129
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Gaia Medical Institute