Clinical trials: Hypertrophy
Proteomics, Exercise
Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading
Skeletal muscle plays several different roles in the promotion and maintenance of health and well-being. The loss of muscle mass that occurs with aging, chronic muscle wasting diseases, and physical inactivity puts people at an…
- Conditions
- Proteomics, Exercise, Atrophy, Disuse, Hypertrophy
- Trial name
- HYPAT (NCT04514744)
- Testing
- Knee bracing, Unilateral Resistance Exercise Training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster University
Muscle Hypertrophy in Healthy Young Men
Effects of Deloading Periods in Resistance Training on Muscular Strength and Hypertrophy
This study investigates the effects of deloading periods (short breaks or reductions in training volume) in a 8-week resistance training program on muscle strength and hypertrophy in young, untrained individuals.
- Trial name
- DPRT (NCT06825052)
- Testing
- Resistance Training with Deloading Periods, Continuous Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy
Non-Invasive Evaluation of Myocardial Stiffness by Elastography in Pediatric Cardiology (Elasto-Pédiatrie)
First, investigators must determine the physiological standards across age classes of myocardial stiffness estimated by Elastography in ultrafast (estimated right ventricular stiffness [VD] and left ventricular [LV]).
- Trial name
- NCT02619825
- Testing
- Echography, Elastography
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Prostatic Hyperplasia, Prostatic Hypertrophy, Benign
Medical Therapy of Prostatic Symptoms
The Medical Therapy of Prostatic Symptoms (MTOPS) is a clinical research study sponsored by the National Institutes of Health (NIH).
- Trial name
- MTOPS (NCT00021814)
- Testing
- Doxazosin, Finasteride
- Where
- 17 sites in United States
- Volunteers
- 3,407 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Lingual Tonsil Hypertrophy, Dysphagia
Lingual Tonsil Hypertrophy Grading and Its Relation to Sociodemographic Factors and Clinical Symptoms
The aim of this research was to evaluate the lingual tonsil hypertrophy (LTH) grading of patients with dysphagia using videolaryngoscopy and determine the relation of LTH grades to sociodemographic factors and clinical symptoms.
- Trial name
- NCT02926014
- Testing
- Videolaryngoscopy, Reflux Symptom Index Questionnaire, Dysphagia Screening Questionnaire
- Where
- Lithuania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Modified Ridge Splitting Technique Using Autogenous Bone Blocks (MRS)
In this clinical study ridge splitting procedures are preformed using autogenous bone blocks. After a 3-month healing, at the time of dental implant placement bone core biopsy samples are harvested.
- Trial name
- MRS (NCT05005858)
- Testing
- Alveolar ridge splitting, Creating osteotomies with piezoelectric device
- Where
- Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Fabry Disease
FASHION Fabry Disease Hypertrophic Cardiomyopathy and Infammation
In Fabry disease (FD) and hypertrophic cardiomyopathy (HCM) systemic inflammation recently gained attention as a possible key pathophysiologic process involved in the development of cardiac hypertrophy and progression of the…
- Trial name
- FASHION (NCT05761834)
- Testing
- Sample blood and 2D-echocardiography with Doppler
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hypertrophic Cardiomyopathy
A Trial of HRS-1893 in Healthy Volunteers
The purpose of this study is to assess the safety and PK characteristics of a single oral dose of HRS-1893 in healthy voluunters.
- Trial name
- NCT07033455
- Testing
- HRS-1893
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Atridia Pty Ltd.
Benign Prostate Hypertrophy(BPH)
A Clinical Trial to Compare and Evaluate Evaluate the Pharmacokinetics and Safety of CKD-846
A Clinical trial to compare and evaluate evaluate the pharmacokinetics and safety of CKD-846
- Trial name
- NCT06110923
- Testing
- CKD-846, D091
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Focus of Study
Can the Hypertrophy of Contralateral Testis Predict the Absence of the Non-palpable Testis in the Boys Aged From 6months to 18months of Age ?
The aim of this study is to verify whether the hypertrophy of contralateral testis may predict the absence of the non-palpable testis in the boys younger than 24months of age.
- Trial name
- NCT02203318
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Scar, Cicatrix
Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2.
The study will investigate the safety and effectiveness of daily post surgical scar management, using a moisture-balancing base product containing different amounts of a novel (NCE) antifibrogenic compound FS2, a natural…
- Conditions
- Scar, Cicatrix, Hypertrophic Scar, Skin Graft Scar
- Trial name
- FS2 (NCT04186273)
- Testing
- Fibrosis-Inhibiting-Compound-FS2, Vehicle moisture balancing base
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cicatrix, Hypertrophic
Fractional CO2 Laser Treatment of Hypertrophic Scars
Executive Summary Hypertrophic scars are irregular, raised scars that can cause debilitating symptoms including pain, pruritus, and restricted movement in nearby joints.
- Trial name
- NCT04236167
- Testing
- Fractional CO2 laser treatment -
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Left Ventricular Hypertrophy
Impact of Physical Activity on Left Ventricular Mass and Lipid Metabolism
Prospective study on the structural and functional changes in the heart of adult women assessed by echocardiogram and in lipid metabolism that occur in response to physical training.
- Trial name
- NCT01199211
- Testing
- Exercise training, women, marathon
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aging, Muscular Atrophy
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults
Resistance training has shown the most promise among interventions aimed to combat aging muscle atrophy as it enhances strength, power, and mobility function, but induces varying degrees of skeletal muscle hypertrophy as the…
- Trial name
- NCT02442479
- Testing
- resistance training
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hypertrophic Obstructive Cardiomyopathy
Mitral Valve in Hypertrophic Cardiomyopathy
The purpose of the study is to assess the role of mitral valve apparatus in the development of outflow tract obstruction in patients with hypertrophic cardiomyopathy and to identify the best surgical treatment modality to relieve…
- Trial name
- NCT03877731
- Testing
- isolated septal myectomy, septal myectomy + edge-to-edge mitral valve repair, septal myectomy + posterior leaflet sliding plasty
- Where
- Russia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Healthy
Plant-based Dietary Protein and Resistance-training Adaptations
Dietary protein consumption maximizes the anabolic response during resistance training (RT) by triggering muscle protein synthesis and providing the indispensable amino acids for a net positive protein balance.
- Trial name
- NCT03907059
- Testing
- whey protein, soy protein
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hypertension
Salt-sensitive Hypertension Study in Lantian County
Essential hypertension is a complex trait which results from interaction between environmental factors and genetic factors. Our study aimed to detect the differential expression of LncRNAs and epigenetic changes such as DNA…
- Trial name
- SHSL (NCT02915315)
- Testing
- salt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Breast Reduction
Reduction of Breast Hypertrophy by Means of Coelioscopique Surgery
The objective of this interventional study is based on the hypothesis that coelioscopique surgery could be used to reduce breast hypertrophy.
- Trial name
- R-HTM-R (NCT05822115)
- Testing
- Reduction of breast hypertrophy by means of laparoscopic
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier Nord-Essonne
Sarcopenia, Cardiovascular Disease
Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy
The purpose of this study is to examine the effect of dietary cholesterol administered as whole egg or egg white (control)on muscle mass gain with resistance training in a young old population of men and women (age 50-69).
- Trial name
- NCT00260442
- Testing
- Resistance Training, Sedentary
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Hypertrophic Scar
A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars
The purpose of this study is to determine the effectiveness of RXI-109 in reducing the recurrence of hypertrophic scar formation following elective revision of a pre-existing hypertrophic scar.
- Trial name
- NCT02246465
- Testing
- RXI-109
- Where
- 6 sites in United States, Honduras
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.