Clinical trials: Hypochlorous Acid
Oral Mucosal Disorder
Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa
The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa.
- Trial name
- NCT06942026
- Testing
- Control 1
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Eye Infections, Bacterial
Comparison of Conjunctival Antimicrobial Activity and Patient Comfort Between Topical Hypochlorous Acid (Avenova) and Betadine
The purpose of this research study is to find out how Avenova (0.01 % hypochlorous acid) works compared to Betadine (Povidone iodide) for reducing bacteria and patient discomfort in the eyes.
- Trial name
- NCT04981860
- Testing
- Betadine, Avenova
- Where
- 2 sites in United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dry Eye
Efficacy and Safety of Ocudox Lid Wipes Compared to Traditional Lid Cleaning
The use of povidone iodine solution for prophylaxis of endophthalmitis is well established for intraocular procedures like cataract surgery and for injections of anti-VEGF agents for retinal diseases such as age-related macular…
- Trial name
- NCT03763006
- Testing
- Eyelid cleaning
- Where
- Singapore
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Periodontitis, Periodontitis Stage I
Hypochlorous Acid in Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammatory disease associated with dental plaque and characterized by the progressive destruction of the tooth-supporting tissues.
- Conditions
- Periodontitis, Periodontitis Stage I, Periodontitis Stage II
- Trial name
- NCT07712627
- Testing
- Hypochlorous Acid Application, Scaling and Root Planing (SRP) with Purified Water
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Newborn; Infection, Disinfection
Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used
Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract Aim: Circumcision is one of the most common surgical procedures in all age groups.
- Conditions
- Newborn; Infection, Disinfection, Circumcision
- Trial name
- NCT05175027
- Testing
- hypochlorous acid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Vascular Prosthetic Graft Infection
Prevention of Vascular Graft Infection With Hypochlorous Acid
This is a study of the use of an antibacterial solution, Hypochlorous acid, to prevent infection in vascular surgery bypass grafts.
- Trial name
- NCT07678632
- Testing
- Hypochlorous acid
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Hamilton Health Sciences Corporation
Wound Healing
Efficacy of Hypochlorous Acid as a Postoperative Wound Antiseptic
The aim was to examine the effectiveness of hypochlorous acid on postoperative wound healing in 24 systemically healthy gingivectomy participants aged 12-30.
- Trial name
- NCT06760403
- Testing
- Hypochlorous acid
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Impacted Mandibular Third Molar
Comparison of Chlorhexidine and Hypochlorous Acid Mouthwash After Impacted Third Molar Surgery
Impacted mandibular third molar extraction is one of the most common procedures in oral and maxillofacial surgery and is frequently associated with postoperative complications such as pain, edema, and trismus, which may…
- Trial name
- NCT07466992
- Testing
- Hypochlorous Acid, Chlorhexidine Gluconate Mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
SARS-CoV Infection, Covid19
Use of Hypochlorous Acid as Prophylaxis in Health Personnel at High Risk of Infection by SARS-CoV 2 (COVID19)
The pandemic caused by SARS-CoV-2 is a global emergency present in 6 continents including 66 countries, incurring a shortage of effective and safe therapeutic alternatives that can contribute to reducing the risk of…
- Conditions
- SARS-CoV Infection, Covid19, Infection Viral
- Trial name
- NCT04684550
- Testing
- Stabilized hypochlorous acid
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital Universitario San Ignacio
Surgical Site Infection
Wound Antiseptic Study With Hypochlorous Acid & Iodopovidone
The purpose of this study is to determine whether hypochlorous acid is an effective antiseptic agent to prevent surgical site infection.
- Trial name
- WASH (NCT00692757)
- Testing
- Hypochlorous acid, Iodopovidone
- Where
- Colombia
- Volunteers
- 432 people
- Sponsor
- Universidad Tecnológica de Pereira
SARS CoV 2 Infection
Use of a Hypochlorous Acid Spray Solution in the Treatment of COVID-19 Patients : COVICONTROL Study .
The objective is To evaluate the efficacy and safety of nasal spray and mouth spray application with hypochlorous acid-containing solution versus placebo as a curative treatment for hospitalized SARS-CoV-2 positive patients And…
- Trial name
- COVICONTROL (NCT05862480)
- Testing
- Spray with Hypochlorous Acid Group
- Where
- Tunisia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Dental Plaque
Comparison of the Clinical and Microbiological Effects of CHX and HOCl Containing Mouthwashes
The primary objective of the study is to compare the antiplaque and anti-inflammatory effects of HOCl mouth rinse with those of CHX mouth rinse.
- Trial name
- NCT06589193
- Testing
- HOCl, CHX
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Baskent University
Blepharitis
0.01% Hypochlorous Acid in the Treatment of Blepharitis
This is a multi-center, multidisciplinary, open-label, randomized controlled prospective clinical study.
- Trial name
- NCT05608980
- Testing
- 0.01% hypochlorous acid
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract, Endophthalmitis
Hypochlorous Acid Disinfection Prior to Cataract Surgery
Antibiotics are commonly utilized to reduce the bacterial population of the eye prior to surgery with the assumption that this reduces the risk of endophthalmitis, although it is not clear if this actually occurs.
- Trial name
- NCT04568213
- Testing
- Hypochlorous Acid Gel 0.02%
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Loma Linda University
Fissure Sealant
The Effect of Different Deproteinising Agents on the Clinical Success of Fissure Sealants in Permanent Teeth
Investigation of the effect of deproteinization agents on the clinical success of non-invasive fissure sealant application, which is a non-invasive method used to prevent caries formation or to stop the progression of initial…
- Trial name
- NCT06988098
- Testing
- application of deproteinization agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Diabetic Foot Ulcer
Treating Diabetic Foot Ulcers, Comparing Two Topical Antimicrobial Agents, Dakin´s and Prontosan
202 Diabetic foot ulcers will be cleaned with either Hypochlorous Acid, HClO or Polyhexamethylene biguanide, PHMB twice a week until healed or 24 weeks.
- Trial name
- NCT05132179
- Testing
- Dakins Full Strength Solution, 0.5% Topical Solution, HOCl solution
- Where
- Sweden
- Volunteers
- 202 people
- Sponsor
- Vastra Gotaland Region
Ventilator-Associated Pneumonia
The Effect of Solutions Used in Oral Care on Preventing Ventilator-Associated Pneumonia.
The goal of this clinical trial is to learn about effects of chlorhexidine gluconate, sodium bicarbonate, ozonated water and hypochlorous acid solutions used in oral care of patients on mechanical ventilation support on…
- Trial name
- NCT06118242
- Testing
- Use of oral care solutions
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Aydin Adnan Menderes University
Periodontal Diseases, Chronic Periodontitis
Comparison of the Effectiveness of Hypochlorous Acid and Chlorhexidine as a Post-surgical Antimicrobial Agent
The aim of the study is to evaluate the effectiveness of Hypochlorous Acid and Chlorhexidine as postsurgical antimicrobial agents in the treatment of severe chronic periodontal disease.
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Microbial Colonization
- Trial name
- HOCl-Post-AA (NCT05952921)
- Testing
- Mouthwash, Chlorhexidine
- Where
- Colombia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Periodontal Diseases
Hypochlorous Acid Mouthwash, Oral Bacteria, and Staphylococcus Aureus
Mouthwash is one method of maintain oral health and to reduce the dental plaque and gum inflammation. However, the effects of mouthwash on oral bacteria were not consistent among different brands of them.
- Trial name
- NCT05372835
- Testing
- La Chlogen mouthwash, water, La Chlogen mouthwash and La Chlogen periodontal flosser
- Where
- Taiwan
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University