Clinical trials: Hypoventilation
Slow Breathing
Assessing the Acute Effects of Virtual Reality Interventions on Stress
A Four-Arm RCT, testing the acute effects of a Virtual Reality (VR)- based slow-paced breathing intervention on subjective and physiological markers of stress.
- Trial name
- VR_Stress_25 (NCT07191288)
- Testing
- VR (VR-Breathing+Mystical), VR (VR-Mystical), Computer (Non-VR-Breathing)
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Obstructive Sleep Apnoea (OSA), Hypoventilation Syndrome
Sleep-disordered Breathing Database
The goal of this study is to collect clinical data on patients who have had a sleep study and are given a diagnosis of a sleep related breathing disorder such as obstructive sleep apnoea.
- Trial name
- NCT07402603
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Normobaric Hypoxia, Hypoventilation
Influence of Hypoxic, Normobaric and Hypobaric Training on the Immunometabolism of Post-covid-19 Athletes
COVID-19 has significantly impacted sports globally, with event postponements, training disruptions, and wide-ranging concerns. SARS-CoV-2 infection can result in hyperinflammation and cardiopulmonary changes, with hypoxia as an…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06128941
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Hypoventilation, Hyperventilation
Investigating the Effect of Yoga-based Breathing Styles on the Human Brain, With a Focus on Memory
The goal of this clinical trial is to learn if yoga-based breathing styles could improve memory performance in adult persons without relevant prior experience in yoga, meditation or similar disciplines and without existing health…
- Trial name
- NCT05846425
- Testing
- Nose-breathing training, Mouth-breathing training
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Sleep Wake Disorders
The Effectiveness of Lavender Aromatherapy Combined With Slow Breathing Exercises in Improving Occupational Burnout and Sleep Disorders Among Nursing Staff
This study investigates the effects of breathing exercises combined with lavender essential oil inhalation on occupational burnout and sleep disturbances in rotating shift nurses.
- Trial name
- NCT06914167
- Testing
- Slow Breathing Exercises, Lavender Essential Oil Inhalation, linalyl acetate essential oil Inhalation
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Anxiety, Stress
Breathing for Adolescent Stress Reduction Feasibility RCT
The purpose of this study was to test a simple slow breathing curriculum for reducing stress among high school students. The curriculum was developed by the Health and Human Performance Foundation and implemented for this study…
- Trial name
- NCT05266833
- Testing
- Slow diaphragmatic breathing
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Health and Human Performance Foundation
Morbid Obesity, Bariatric Surgery
Study to Determine Incidence of Hypoventilation in Patients Who Have Undergone Gastric Bypass
The purpose of this study is to determine if gastric bypass patients experience hypoventilation in the immediate postoperative period, and to what degree.
- Trial name
- NCT00316446
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Heart Failure
Short Term Hemodynamic Effects of Controlled Slow Breathing With Biofeedback in Patients With Heart Failure
Heart failure is associated with faster breathing, which has a negative impact on the functioning of the heart. This leads to fatigue, shortness of breath, and exercise intolerance.
- Trial name
- NCT00971386
- Testing
- Slow breathing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Stress, Stress, Psychological
Interactive Effects of Mindfulness and Slow-paced Breathing
The purpose of this study is to better understand specific stress-management practices on mood, sleep, and physiology. Participants will be assigned to one of three interventions (they all active interventions - none are a…
- Conditions
- Stress, Stress, Psychological, Stress Physiology, Sleep
- Trial name
- NCT04866901
- Testing
- Slow-Paced Breathing (SPB), Mindfulness (M), Yogic Breathing (SPB+M)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Congenital Central Hypoventilation Syndrome
Late-onset Congenital Central Hypoventilation Syndrome and the Mutation of Phox2B Gene
Congenital central hypoventilation syndrome (CCHS) is a rare disorder of respiratory control characterized by ventilatory impairment that results in arterial hypoxemia.
- Trial name
- CCHS (NCT01225679)
- Testing
- positive airway pressure, Non-invasive mechanic ventilation
- Where
- Brazil
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Gastrostomy, Ventilatory Failure
Concomitant Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy
The goal of this research study is to assess the FDA approved technique for inserting a feeding tube (gastrostomy) along with a breathing tube (tracheostomy) for patients that cannot breathe or eat on their own in the ICU…
- Conditions
- Gastrostomy, Ventilatory Failure, Respiratory Failure
- Trial name
- TPUG (NCT05955534)
- Testing
- TPUG, PEG, PRG
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Alveolar Hypoventilation Resulting in Hypoxemia
Capnography During Nurse Administered Propofol Sedation
Rationale: The current standard of respiratory monitoring for patients during deep sedation is continuous pulse oximetry with visual assessment of the patient.
- Trial name
- NCT01220765
- Testing
- Capnography
- Where
- Netherlands
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Sleep
Influence of Yogic Breathwork on Sleep
The purpose of this research study is to determine the influence of a regular yogic breathing practice on sleep, and to find out primarily if a regular practice of 8-week yogic breathing would enhance sleep quality as well as if…
- Trial name
- NCT05756686
- Testing
- Breathing Group 1, Breathing Group 2
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypoventilation
Positive Pressure and Gravity Affect Volumetric Capnography
Volumetric capnography is an interesting and non-invasive tool for monitoring ventilation in mechanically ventilated patients. The aim of this study was to test the effect of positive pressure ventilation and different body…
- Trial name
- NCT03853057
- Testing
- body positions
- Where
- Argentina
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Drug Overdose, Opioid-Related Disorders
Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose
RTM Vital Signs, LLC is developing a miniature wearable tracheal sound sensor that communicates with a cell phone containing a machine-learning diagnostic algorithm designed to detect and predict the onset of mild, moderate, and…
- Trial name
- NCT03845699
- Testing
- Diagnostic algorithms that detects/predicts hypoventilation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RTM Vital Signs, LLC
Ventilatory Failure
Neo RQI: The Effect of Neonatal Resuscitation Quality Improvement Cart Booster Training Skills Retention
This is a prospective multicenter randomized control trial to assess percentage mask leak six months post instructor led positive pressure ventilation skills training in providers who undergo booster training compared to those…
- Trial name
- NCT05147922
- Testing
- Booster Training with the Neonatal Resuscitation Quality Improvement Cart
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Congenital Central Hypoventilation Syndrome (CCHS)
Identifying Biomarkers & Dysregulated Biological Pathways in Blood and Urine of Congenital Central Hypoventilation Syndrome (CCHS) Patients
The CCHS study is a prospective, open-label, monocentric, interventional study with diagnostic and prognostic objectives, conducted in two phases.
- Trial name
- CCHSBiomarkers (NCT06997146)
- Testing
- Blood and Urine Sampling, Polysomnography, lung function tests
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Slow Breathing, Acute Myocardial Infarction
The Effect of Slow Breathing Exercise Applied to Patients on Pulse, Blood Pressure and Quality of Life
This study was designed as a randomized controlled experimental type in order to determine the effect of slow breathing exercise applied after the procedure on heart rate, blood pressure and quality of life in patients who…
- Trial name
- NCT06098222
- Testing
- Slow breathing exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi